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المؤلفون: Gloria Gutiérrez-Venegas, Berenice Fernández-Rojas, José Pedraza-Chaverri, Gustavo Ignacio Vázquez-Cervantes
المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 101-108 (2020)مصطلحات موضوعية: Antioxidant, Health, Toxicology and Mutagenesis, medicine.medical_treatment, ERK, extracellular signal-regulated kinases, 010501 environmental sciences, Toxicology, medicine.disease_cause, 01 natural sciences, GPx-1, glutathione peroxidase-1, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, chemistry.chemical_compound, 0302 clinical medicine, Carboxy-H2DCFDA, 6-carboxy-2´,7´ dichlorodihydrofluorescein diacetate, LTA, lipoteichoic acid, GSH, glutathione, ROS production, NOS, nitric oxide synthase, chemistry.chemical_classification, biology, Chemistry, OH•, hydroxyl radical, Glutathione peroxidase, Regular Article, respiratory system, IE, infective endocarditis, Catalase, H2O2, hydrogen peroxide, O2•¯, superoxide radical, Antioxidant enzymes, lipids (amino acids, peptides, and proteins), Lipoteichoic acid, FDA, fluorescein diacetate, JNK, c-jun N-terminal kinases, SOD-1, superoxide dismutase-1, AKT, protein kinase B, ONOO¯, peroxynitrite anion, Microbiology, RNS, reactive nitrogen species, Superoxide dismutase, 03 medical and health sciences, ROS, reactive oxygen species, lcsh:RA1190-1270, medicine, Nrf2, nuclear factor (erythroid-derived 2)-like 2, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, NO, nitric oxide, Reactive oxygen species, Glutathione, Oxidative stress, biology.protein, CAT, catalase, Infective endocarditis, DHE, dihydroethidium, MAPK, mitogen-activated protein kinase, 030217 neurology & neurosurgery
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المصدر: Virus Research
Pieretti, J C, Rubilar, O, Weller, R B, Tortella, G R & Seabra, A B 2020, ' Nitric oxide (NO) and nanoparticles – Potential small tools for the war against COVID-19 and other human coronavirus infections ', Virus Research, vol. 291, pp. 198202 . https://doi.org/10.1016/j.virusres.2020.198202مصطلحات موضوعية: Cancer Research, Coronavirus disease 2019 (COVID-19), NOx, Nitrogen Reactive Species, Potential candidate, SARS-CoV-2, Severe Acute Respiratory Syndrome Corona Virus 2, Review, Biology, Bioinformatics, Nitric Oxide, Antiviral Agents, WHO, World Health Organization, Nitric oxide, No donors, 03 medical and health sciences, chemistry.chemical_compound, Drug Delivery Systems, Virology, Administration, Inhalation, Humans, In patient, RNA, Ribonucleic acid, Antiviral, 030304 developmental biology, No release, ComputingMethodologies_COMPUTERGRAPHICS, 0303 health sciences, O2•-, Superoxide, 030306 microbiology, FDA, US Food and Drug Administration, AgNPs, Silver Nanoparticles, COVID-19, SARS-CoV, Clot formation, Human coronavirus, NO, Nitric Oxide, UVA, Ultraviolet radiation A, COVID-19 Drug Treatment, iNOS, Inducible NO Synthase, ONOO-, Peroxynitrite, Infectious Diseases, chemistry, IDO, Indoleamine 2,3–dioxygenase, Nanoparticles, SNAP, S-nitroso-N-acetylpenicillamine, CuNPs, Copper Nanoparticles, Coronavirus Infections, Inhaled nitric oxide
وصف الملف: application/vnd.openxmlformats-officedocument.wordprocessingml.document
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المؤلفون: Yuanyuan Hu, Beiwei Zhu, Yulin Peng, Guanhua Zhao, Fereidoon Shahidi, Zhenlong Yu, Zhong-Yuan Liu, Fa-Wen Yin, Da-Yong Zhou, Xiaochi Ma
المصدر: Redox Biology, Vol 34, Iss, Pp 101577-(2020)
Redox Biologyمصطلحات موضوعية: 0301 basic medicine, GSSG, Oxidized glutathione, eNOS, Endothelial nitric oxide synthase, Bcl-2, B-cell lymphoma 2, p-ERK1/2, p-eNOSSer1177, Clinical Biochemistry, MAPK, Mitogen-activated protein kinase, Apoptosis, medicine.disease_cause, Biochemistry, Endothelial nitric oxide synthase serine 1177 phosphorylation, p-VASP, Umbilical vein, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, O2−, Superoxide, Reactive oxygen species, SMT, Endothelial dysfunction, Trans, Mesenteric arteries, lcsh:QH301-705.5, reproductive and urinary physiology, lcsh:R5-920, Phosphorylation of vasodilator-stimulated phosphoprotein, ROS, food and beverages, Trans, trans-2,4-decadienal, medicine.anatomical_structure, JNK, c-Jun N-terminal kinase, embryonic structures, Blood pressure, NADPH, Nicotinamide adenine dinucleotide phosphate, lcsh:Medicine (General), Peroxynitrite, Research Paper, medicine.medical_specialty, endocrine system, Bax, BCL-2 associated X protein, Sodium nitroprusside, tt-DDE, GSH, Reduced glutathione, trans-2,4-decadienal, 03 medical and health sciences, Internal medicine, medicine, Animals, MMP, Mitochondrial membrane potential, Endothelium, l-NAME, Nω-nitro-l-arginine methylester, LDH, Lactate dehydrogenase, Aldehydes, ACh, Acetylcholine, organic chemicals, Organic Chemistry, medicine.disease, ONOO−, Peroxynitrite, iNOS, Inducible nitric oxide synthase, Rats, 030104 developmental biology, Endocrinology, chemistry, lcsh:Biology (General), Oxidative stress, Pathophysiology of hypertension, HUVECs, Human umbilical vein endothelial cells, LDL, Low-density lipoprotein, S-methylisothiourea, SNP, Endothelium, Vascular, Nitrative stress, 030217 neurology & neurosurgery
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المؤلفون: Hegedűs, Csaba, Kovács, Katalin, Polgár, Zsuzsanna, Regdon, Zsolt, Szabó, Éva, Robaszkiewicz, Agnieszka, Forman, Henry Jay, Martner, Anna, Virág, László
المصدر: Redox Biology, Vol 16, Iss, Pp 59-74 (2018)
Redox Biologyمصطلحات موضوعية: PARP1, Poly (ADP-ribose) polymerase 1, TGFβ, Transforming growth factor beta, GFR, growth factor receptor, NQO1, NAD(P)H:quinone oxidoreductase 1, DAMP, damage-associated molecular pattern, MAP, mitogen-activated protein, MAPKKK, mitogen-activated protein kinase kinase kinase, NAC, N-acetylcysteine, Free radicals, Review Article, PD-L1, Programmed death-ligand 1, Nrf2, nuclear factor erythroid 2-related factor 2, Antioxidants, Her/hER, human Estrogen Receptor, HDC, histamine dihydrochloride, ADCC, antibody-dependent cell-mediated cytotoxicity, ERK, extracellular signal-regulated kinase, HIF-1 α, hypoxia inducible factor 1α, IL-2, Interleukin-2, DCFH 2', 7'-dichlorodihydrofluorescein, GSH, glutathione, Elméleti orvostudományok, NOS, nitric oxide synthase, AML, acute myeloid leukemia, LPS, Lipopolysaccharide, lcsh:QH301-705.5, Cancer, FAS, first apoptosis signal, PBMC, Peripheral blood mononuclear cell, MΦ, macrophage, EGF, Epidermal growth factor, lcsh:Medicine (General), ImC, immaturemyeloid cell, PhGPx, phospholipid hydroperoxide glutathione peroxidase, PDGF, Platelet-derived growth factor, Chemotherapeutics, Antineoplastic Agents, PI3K, Phosphatidylinositol 3-kinase, DDR, DNA damage response, TAMs, tumor-associated macrophages, Humans, ILT, immunoglobulin like transcripts, KIR, killer immunoglobulin-like receptor, DDB, Biphenyl Dimethyl Dicarboxylate, CAF, cancer-associated fibroblast, CLs, cytotoxic lymphocytes, NO, nitric oxide, APE1, apurinic/apyrimidinic endonuclease 1, TRAIL, TNF-related apoptosis-inducing ligand, TrxR1, thioredoxin reductase 1, CTL, cytotoxic T lymphocyte, PD1, Programmed cell death protein 1, ASK-1, apoptosis signal-regulated kinase 1, HMGB1, high mobility group box 1, Redox regulation, PK, pyruvate kinase, Reactive Oxygen Species, ADCP, antibody-dependent cancer cell phagocytosis, eNOS, Endothelial NOS, cPLA, cytosolic phospholipase A, GST, Glutathione transferase, NSCLC, Non-Small Cell Lung Cancer, LOOH, lipid hydroperoxide, NFκB, nuclear factor kappa-light-chain-enhancer of activated B cells, VEGF, Vascular endothelial growth factor, ABC transporters, ATP-binding cassette transporters, PEDF, pigment epithelium derived factor, PGE2, Prostaglandin E2, MHC-I, major histocompatibility complex type I, M-CSF, macrophage colony-stimulating factor, Neoplasms, PDT, Photodynamic therapy, NK, Natural Killer cells, TNF, tumor necrosis factor, lcsh:R5-920, GPx, glutathione peroxidase, TCR, T cell receptor, Orvostudományok, MnTBAP, Mn(III)tetrakis (4-benzoic acid) porphyrin, Natural killer cells, DCs, dendritic cells, Oxidation-Reduction, Signal Transduction, MDSC, myeloid derived suppressor cell, TLR, Toll-like receptor, CTLA-4, cytotoxic T-lymphocyte-associated protein 4, EMT, epithelial mesenchymal transition, ER, Endoplasmic reticulum, Cytotoxic lymphocytes, Dox, doxorubicin, CAR-T cells, Chimeric Antigen Receptor T-Cell, SOD, superoxide dismutase, EGFR, Epidermal growth factor receptor, MDR, multiple drug resistance, DUOX, nicotinamide adenine dinucleotide phosphate (NADPH) dual oxidase, nNOS, Neuronal NOS, LPO, lipid peroxidation products, NADPH, nicotinamide adenine dinucleotide phosphate, NCR, natural cytotoxicity receptor, CLL, chronic lymphoid leukemia, Oxidative Stress, NOX, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, lcsh:Biology (General), GM-CSF, Granulocyte-macrophage colony-stimulating factor, ETO, etoposide, ONOO-, peroxynitrite
وصف الملف: application/pdf
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المؤلفون: Irene Stafford, Sujith Chacko, B. Raman, Matthew Chapman, Giovanni Licari, John D. Horowitz, Michael P. Frenneaux, Sven Y. Surikow, Thanh H Nguyen, Doan T.M. Ngo, S. Chua, Yuan Zhang, Darren J. Kelly, Mark T. Waddingham, Alexander P. Bate, Kuljit Singh
المصدر: JACC: Basic to Translational Science, Vol 3, Iss 2, Pp 213-226 (2018)
JACC: Basic to Translational Scienceمصطلحات موضوعية: 0301 basic medicine, Cardiac function curve, ISO, isoproterenol, medicine.medical_specialty, lcsh:Diseases of the circulatory (Cardiovascular) system, PARP, poly(ADP-ribose) polymerase, 3AB, 3-aminobenzamide, Poly ADP ribose polymerase, poly(ADP-ribose) polymerase-1, 030204 cardiovascular system & hematology, medicine.disease_cause, Nitric oxide, PRECLINICAL RESEARCH, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, oxidative stress, O2–, superoxide, NOS, nitric oxide synthase, LV, left ventricular, ANOVA, analysis of variance, TS, Takotsubo syndrome, NT, nitrotyrosine, myocardial inflammation, NO, nitric oxide, biology, Nitrotyrosine, TXNIP, thioredoxin-interacting protein, Nitric oxide synthase, 030104 developmental biology, Endocrinology, chemistry, 3-Aminobenzamide, lcsh:RC666-701, NFκB, nuclear factor kappa B, biology.protein, Takotsubo cardiomyopathy, PAR, poly(ADP-ribose), ONOO–, peroxynitrite, Cardiology and Cardiovascular Medicine, Oxidative stress, Peroxynitrite
وصف الملف: application/pdf
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المؤلفون: Reinaldo Marín, Flor H. Pujol, Deliana Rojas, Luis Sobrevia
المصدر: Biochimica et Biophysica Acta. Molecular Basis of Disease
مصطلحات موضوعية: TNF-α, tumour necrosis factor-alpha, Placenta, TMPRSS2, transmembrane serine protease type 2, HIF-1α, hypoxia-inducible factor 1 alpha, Ang 1–7, angiotensin 1-7, IL-8, interleukin 8, TNF, tumour necrosis factor, HIF-2α, hypoxia-inducible factor 2 alpha, AT1, angiotensin receptor 1, Pre-Eclampsia, Pregnancy, reproductive and urinary physiology, COVID-19, coronavirus disease 2019, loPE, late-onset preeclampsia, PlGF, placental growth factor, VEGF, vascular endothelial growth factor, IL-6, interleukin 6, sFlt-1, soluble fms-like tyrosine kinase-1, H2O2, hydrogen peroxide, Molecular Medicine, Female, 1O2, singlet oxygen, Human, ACE, angiotensin-converting enzyme, NADH, nicotinamide adenine dinucleotide reduced form, CTB, cytotrophoblast, ACE2, angiotensin-converting enzyme 2, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, Article, ROS, reactive oxygen species, •OH, hydroxyl radicals, SOD, superoxide dismutase, •O2−, superoxide anion, Animals, Humans, STB, syncytiotrophoblast, Molecular Biology, Ang II, angiotensin II, eoPE, early-onset preeclampsia, NF-κB, nuclear transcription factor-kappa B, SARS-CoV-2, COVID-19, RAS, renin-angiotensin system, NADPH, nicotinamide adenine dinucleotide phosphate, Preeclampsia, ONOO−, peroxynitrite, Oxidative Stress, NO•, nitric oxide, IL-10, interleukin 10, ADAM17, a disintegrin and metalloprotease 17, CAT, catalase
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المؤلفون: Chuan Han Jonathan Foo, Shazib Pervaiz
المصدر: Redox Biology, Vol 25, Iss, Pp-(2019)
Redox Biologyمصطلحات موضوعية: GSSG, Glutathione disulfide, DUOX, Dual oxidase, FOXO3A, Forkhead box O3a, Rac, Ras-related C3 botulinum toxin substrate, Biochemistry, GAP, GTPase-activating protein, 0302 clinical medicine, Fe2+, Iron (II) ion, TNF-α, Tumor necrosis factor-α, NSCLC, Non-small cell lung cancer, NOS, Nitric oxide synthase, lcsh:QH301-705.5, Cancer, Mutation, Trx, Thioredoxin, ERK, Extracellular signal-regulated kinase, miR, Micro-Ribonucleic acid, FMN, Flavin mononucleotide, GSR, Glutathione disulfide reductase, Keap1, Kelch-like ECH-associated protein 1, TRAF, TNFR-associated factor, IMM, Inner mitochondrial membrane, MnSOD/SOD2, Manganese superoxide dismutase, NF-κB, Nuclear factor kappa-light-chain-enhancer of B cell, EGF, Epidermal growth factor, ATP, Adenosine triphosphate, NADPH, Nicotinamide adenine dinucleotide phosphate, RNS, Reactive nitrogen species, GTP, Guanosine triphosphate, lcsh:Medicine (General), PPP, Pentose Phosphate Pathway, SESN, sestrin, Ca2+, Calcium (ii) ion, DRP1, Dynamin-related protein 1, GEF, GTP exchange factors, NO, Nitric oxide, Article, ECSOD/SOD3, Extracellular superoxide dismutase, 03 medical and health sciences, Atg, Autophagy-related, Humans, Cell Lineage, TrxR, Thioredoxin reductase, O2, Oxygen, PTEN, Phosphatase and tensin homolog, MPK, MAPK phosphatase, mTOR, Mammalian target of rapamycin, RAF, Rapidly Accelerated Fibrosarcoma, Zn2+, Zinc (II) ion, mTORC1, Mammalian target of rapamycin complex 1, medicine.disease, SASP, Senescence-associated secretory phenotype, 030104 developmental biology, ONOO-, Peroxynitrite, CuZnSOD/SOD1, Copper Zinc superoxide dismutase, Cancer cell, ras Proteins, Prx, Peroxiredoxin, Carcinogenesis, Reactive Oxygen Species, Neuroscience, 030217 neurology & neurosurgery, RAS, 0301 basic medicine, MKLK, Mixed lineage kinase domain like pseudokinase, Clinical Biochemistry, MAPK, Mitogen-activated protein kinase, H2O2, Hydrogen peroxide, medicine.disease_cause, PI3K, phospoinositide-3-kinase, PDI, Protein disulfide isomerase, SOD, Superoxide dismutase, DNA, Deoxyribonucleic acid, Neoplasms, GAPDH, Glyceraldehyde-3-phosphate dehydrogenase, GDP, Guanosine diphosphate, TCA cycle, Citric acid cycle, GSH, Glutathione, lcsh:R5-920, HOCl, Hypochlorous acid, AKT, Protein kinase B, Nrf2, Nuclear factor erythroid-related factor 2, NOX, NADPH oxidase, JNK, c-Jun N-terminal Kinase, RIPK, Receptor interacting protein kinase, GPx, Glutathione peroxidase, Pim1, Proto-oncogene serine/threonine-protein kinase Pim-1, Cu2+, Copper (II) ion, Oxidation-Reduction, PTP, protein tyrosine phosphatase, SH2, Src homology 2, Signal Transduction, GLUT1, Glucose transporter 1, Cellular functions, O2•-, Superoxide anion, Biology, •HO, Hydroxyl radical, Dual role, ER, Endoplasmic reticulum, TNFR, Tumor necrosis factor receptor, MEK, Mitogen-activated protein kinase kinase, RAS, Rat sarcoma, medicine, Animals, Mn3+, Manganese (III) ion, G6PD, Glucose-6-phosphate dehydrogenase, BAX, Bcl-2-associated X protein, Cell growth, Organic Chemistry, ASK1, Apoptosis signal-regulating kinase 1, ETC, Electron transport chain, lcsh:Biology (General), DPI, Diphenyleneiodonium, •NO2, Nitrogen dioxide, ROS, Reactive Oxygen Species
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المؤلفون: Sudheer K. Mantena, Kimberly J. Dunham-Snary, Corinne E. Griguer, Claudia R. Oliva, Adrienne L. King, Telisha Millender-Swain, Shannon M. Bailey, Kelly K. Andringa
المصدر: Redox Biology
Redox Biology, Vol 9, Iss C, Pp 188-197 (2016)مصطلحات موضوعية: 0301 basic medicine, Alcoholic liver disease, S-Adenosylmethionine, Bioenergetics, Clinical Biochemistry, Alcohol, Mitochondria, Liver, Mitochondrion, Biochemistry, Mitochondrial Membrane Transport Proteins, chemistry.chemical_compound, 0302 clinical medicine, CsA, cyclosporin A, GSH, glutathione, Hypoxia, lcsh:QH301-705.5, 2. Zero hunger, lcsh:R5-920, Organelle Biogenesis, SAM, S-adenosylmethionine, O2•-, superoxide anion, 3. Good health, Mitochondria, Liver, 030220 oncology & carcinogenesis, iNOS, inducible nitric oxide synthase, medicine.symptom, RCR, respiratory control ratio, lcsh:Medicine (General), HIF1α, hypoxia-inducible factor 1 alpha, Research Paper, Fatty Liver, Alcoholic, medicine.medical_specialty, Cell Respiration, Biology, Nitric Oxide, MPT, mitochondrial permeability transition, Nitric oxide, RNS, reactive nitrogen species, Electron Transport Complex IV, 03 medical and health sciences, ROS, reactive oxygen species, Internal medicine, ALT, alanine aminotransferase, medicine, Animals, NO, nitric oxide, Electron Transport Complex I, Ethanol, Mitochondrial Permeability Transition Pore, Organic Chemistry, Glutathione, Hypoxia (medical), medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Endocrinology, CN-PAGE, clear native polyacrylamide gel electrophoresis, lcsh:Biology (General), chemistry, Mitochondrial permeability transition pore, Reactive Oxygen Species, ONOO-, peroxynitrite, Biomarkers
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المؤلفون: Margaret E. Tome, Ines Batinic-Haberle
المصدر: Redox Biology
Redox Biology, Vol 25, Iss, Pp-(2019)مصطلحات موضوعية: GSSG, glutathione disulfide, S-glutathionylation, MnTE-3-PyP5+, Mn(III) meso-tetrakis(N-ethylpyridinium-3-yl)porphyrin, CuZnSOD, copper, zinc superoxide dismutase (SOD1), Biochemistry, MnTSPP3-, Mn(III) meso-tetrakis(4-sulfonatophenyl)porphyrin, 0302 clinical medicine, SOD mimics, GSH, glutathione, NF-кB, Nuclear factor кB, ProtCys-SH, reduced protein cysteine, Redox biology, lcsh:QH301-705.5, chemistry.chemical_classification, MnT-2-PyP+, Mn(III) meso-tetrakis(N-pyridinium-2-yl)porphyrin, Keap1, Kelch-like ECH-associated protein 1, iNOS, inducible nitric oxide synthase, MnTMOE-3-PyP5+, Mn(III) meso-tetrakis(N-(2′-methoxyethyl)-3-yl)porphyrin, HSP, heat shock protein, lcsh:Medicine (General), MCAO, middle cerebral artery occlusion: MEKK, mitogen-activated protein kinase kinase kinase 1, MnTnOct-2-PyP5+, Mn(III) meso-tetrakis(N-n-octylpyridinium-2-yl)porphyrin, IDH, isocitrate dehydrogenase, MnCl4TE-2-PyP5+, Mn(III) β-tetrachloro-meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, EC-SOD, extracellular superoxide dismutase (SOD3), MnTM-3-PyP5+, Mn(III) meso-tetrakis(N-methylpyridinium-3-yl)porphyrin, Article, MnTnOct-3-PyP5+, Mn(III) meso-tetrakis(N-n-octylpyridinium-3-yl)porphyrin, Txndc 5&9, Thioredoxin domain containing proteins 5&9, MnTBAP3-, Mn(III) meso-tetrakis(4-carboxylatophenyl)porphyrin, 03 medical and health sciences, In vivo, MnTnHex-2-PyP5+, Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, BMX-001, Humans, MnTE-2-PyPhP5+, Mn(III) meso-tetrakis(phenyl-4′-(N-ethylpyridinium-2-yl))porphyrin, •NO, nitric oxide, MnBr8TM-3 or 4-PyP4+, Mn(II) beta-octabromo-meso-terakis(N-methylpyridium-3(or 4)-yl)porphyrin, MnCl5TE-2-PyP5+, Mn(III) β-pentachloro-meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, Mn porphyrins, MnSOD, manganese superoxide dismutase (SOD2), LPx, lipid peroxidase, O2•-, superoxide, 030104 developmental biology, chemistry, Protein cysteines, 030217 neurology & neurosurgery, MAPK, mitogen-activated protein kinase, 0301 basic medicine, MnTnBu-2-PyP5+, Mn(III) meso-tetrakis(N-n-butylpyridinium-2-yl)porphyrin, Clinical Biochemistry, MnTF3Pen-2-PyP5+, Mn(III) meso-tetrakis(N-5′5′,5′-trifluoropentylpyridinium-2-yl)porphyrin, BMX-003, MnTM-4-PyP5+, Mn(III) meso-tetrakis(N-methylpyridinium-4-yl)porphyrin, GST, glutathione S-transferase, polycyclic compounds, S-Glutathionylation, MnTnPr-2-PyP5+, Mn(III) meso-tetrakis(N-n-propylpyridinium-2-yl)porphyrin, lcsh:R5-920, biology, GPx, glutathione peroxidase, MnSOD, Mn superoxide dismutase (SOD2), NOX, NADPH oxidase, PKC, Protein kinase C, MnCl3TE-2-PyP5+, Mn(III) β-trichloro-meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, H2O2, hydrogen peroxide, Thiol, Thermodynamics, MnTE-4-PyP5+, Mn(III) meso-tetrakis(N-ethylpyridinium-4-yl)porphyrin, MnTnBuOE-2-PyP5+, MnBuOE (BMX-001), Mn(III) meso-tetrakis(N-(2′-n-butoxyethyl)pyridinium-2-yl)porphyrin (BMX-001), Oxidation-Reduction, SO32-, sulfite, Cys, Cysteine, TrxR, thioredoxin reductase, MnT-4-PyP+, Mn(III) meso-tetrakis(N-pyridinium-4-yl)porphyrin, Porphyrins, ONOO-, peroxynitrite (stands for both ONOO- and ONOOH), Redox, Catalysis, MnP, manganese porphyrins, Superoxide dismutase, MnTnHex-3-PyP5+, Mn(III) meso-tetrakis(N-n-hexylpyridinium-3-yl)porphyrin, Thiol signaling, ClO-, hypochlorite, Animals, In patient, Sulfhydryl Compounds, MnTnHex-4-PyP5+, Mn(III) meso-tetrakis(N-n-hexylpyridinium-4-yl)porphyrin, Manganese, MnTPhE-2-PyP5+, Mn(III) meso-tetrakis(N-(2′-phenylethyl)pyridinium-2-yl)porphyrin, Superoxide Dismutase, Organic Chemistry, Nrf2, nuclear factor E2-related factor 2, lcsh:Biology (General), MnTE-2-PyP5+, Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin (AEOL10113, BMX-010, MnE), biology.protein, Prx, peroxiredoxin, NHE, normal hydrogen electrode, MnTFE-2-PyP5+, Mn(III) meso-tetrakis(N-fluoroethylpyridinium-2-yl)porphyrn, BMX-002, MnTnHexOE-2-PyP5+, Mn(III) meso-tetrakis(N-(2′-n-hexoxyethyl)pyridinium-2-yl)porphyrin
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المؤلفون: Andrew F, Cumpstey, Magdalena, Minnion, Bernadette O, Fernandez, Monika, Mikus-Lelinska, Kay, Mitchell, Daniel S, Martin, Michael P W, Grocott, Martin, Feelisch
المصدر: Redox Biology
مصطلحات موضوعية: Male, NO2-, nitrite, Short Communication, S2O32-, thiosulfate, cGMP, cyclic guanosine monophosphate, TFT, total free thiols, H2S, hydrogen sulfide, PaO2, arterial partial pressure of oxygen, RNS, reactive nitrogen species, PaCO2, arterial partial pressure of carbon dioxide, LC-ESI-MS/MS, liquid chromatography-electrospray ionization-tandem mass spectrometry, ROS, reactive oxygen species, Thiols, Stress, Physiological, 4-HNE, 4-hydroxynonenal, Humans, Metabolomics, IC-MS, ion chromatography-mass spectrometry, Hypoxia, Exercise, RSS, reactive sulfur species, NO, nitric oxide, CPET, cardiopulmonary exercise testing, EDTA, ethylenediaminetetraacetic acid, Hydrogen sulfide, FRAP, ferric reducing ability of plasma, Altitude, SO42-, sulfate, 8-iso-PG, 8-isoprostaglandin, NO3-, nitrate, RSI, reactive species interactome, Oxygen, Oxidative stress, NEM, N-ethylmaleimide, RSNO, S-nitrosothiol, Female, RXNO, total nitroso species, Blood Gas Analysis, Reactive Oxygen Species, Oxidation-Reduction, ONOO-, peroxynitrite, Biomarkers
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المصدر: Redox Biology
Redox Biology, Vol 13, Iss C, Pp 170-181 (2017)مصطلحات موضوعية: 0301 basic medicine, SIRS, systemic inflammatory response syndrome, STAT3, signal transducer and activator of transcription 3, Clinical Biochemistry, Respiratory chain, DAMP, damage-associated molecular pattern, MAP, mitogen-activated protein, Review Article, Mitochondrion, Bax, BCL2-associated X protein, Biochemistry, 0302 clinical medicine, PCLS, precision cut liver slices, Bcl-xL, B-cell lymphoma-extra large, PK, protein kinase, lcsh:QH301-705.5, SHP1, src homology 1 domain containing protein tyrosine phosphatase, chemistry.chemical_classification, lcsh:R5-920, biology, ATP synthase, TNF alpha, tumor necrosis factor alpha, LD50, median lethal dose, GRIM19, retinoic-interferon-induced mortality, Cell biology, Mitochondria, RIP, receptor-interacting protein, SIR, systemic inflammatory response, TNFR1, TNF receptor type 1, 030220 oncology & carcinogenesis, H2O2, hydrogen peroxide, CLP, cecal ligation and puncture, JNK, c-Jun N-terminal kinase, CyP, cyclophilin, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, Signal transduction, medicine.symptom, lcsh:Medicine (General), JAK, Janus kinase, PAMP, pathogen-associated molecular pattern, Signal Transduction, TLR, Toll-like receptor, MOF, multiple organ failure, ATP, adenosine triphosphate, mPTP, mitochondrial permeability transition pore, Multiple Organ Failure, ANT, adenine nucleotide translocator, Bcl-xL, Inflammation, ER, endoplasmic reticulum, 03 medical and health sciences, ROS, reactive oxygen species, PiC, phosphate carrier, i.v., intravenous, ERK, extracellular-signal regulated, medicine, Animals, Humans, Reactive oxygen species, NO, nitric oxide, Organic Chemistry, Liver failure, ONOO−, peroxynitrite, ADP, adenosine diphosphate, Signaling, IL, interleukin, mtROS, mitochondrial reactive oxygen species, 030104 developmental biology, Mitochondrial permeability transition pore, chemistry, lcsh:Biology (General), Electron Transport Chain Complex Proteins, biology.protein, O2•−, superoxide radical, MODS, multiple organ dysfunction syndrome, MKK4, MAP kinase kinase
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المؤلفون: Ines Batinic-Haberle, Kouros Owzar, Katharina Fleckenstein, Benjamin Gauter-Fleckenstein, Chen Jiang, Júlio S. Rebouças, Artak Tovmasyan, Zeljko Vujaskovic
المصدر: Redox Biology, Vol 2, Iss C, Pp 400-410 (2014)
Redox Biologyمصطلحات موضوعية: HIF-1α, hypoxia inducible factor-1, TF, transcription factor, Radioprotection, Redox-modulators, Clinical Biochemistry, SP-1, specificity protein-1, Pharmacology, Mitochondrion, Infusions, Subcutaneous, medicine.disease_cause, Breathing frequencies, Biochemistry, CO3−, carbonate radical, I/R, ischemia reperfusion, chemistry.chemical_compound, ETC, mitochondrial electron transport chain, GMP, good manufacturing practice, AT, ataxia telangiectasia, ALS, amyotrophic laterial sclerosis, 8-OHdG, 8-hydroxy-2'-deoxyguanosine, Lung, lcsh:QH301-705.5, PI3K, phosphatidylinositide 3-kinase, lcsh:R5-920, O2−, superoxide, Nrf-2, nuclear factor-erythroid-derived 2-like 2, MnTnHex-2-PyP5+, VEGF, vascular endothelial growth factor, Lung injury, Immunohistochemistry, 3. Good health, BBB, blood brain barrier, medicine.anatomical_structure, Toxicity, Female, NF-κB, nuclear factor κB, lcsh:Medicine (General), Oxidation-Reduction, AP-1, activator protein-1, Signal Transduction, medicine.medical_specialty, MnTE-2-PyP5+, Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin (AEOL10113), Metalloporphyrins, HO2−, monodeprotonated hydrogen peroxide, mTOR, mammalian target of rapamycin (mTOR), a serine/threonine protein kinase, Histopathology, Radiation-Protective Agents, CNS, central nervous system, Drug Administration Schedule, Article, NOX4, NADPH oxidase, isoform 4 E1/2, Half-wave metal-centered reduction potential, MnTDE-2-ImP5+, Mn(III) tetrakis[N,N'-diethylimidazolium-2-yl)porphyrin, AEOL10150, GS−, monodeprotonated glutathione, SOD, superoxide dismutase, MnTnBuOE-2-PyP5+, Mn(III) meso-tetrakis(N-(n-butoxyethyl)pyridinium-2-yl)porphyrin, medicine, Animals, MCAO, middle cerebral artery occlusion, NO, nitric oxide, ClO−, hypochlorite, PTEN, phosphoinositide 3-phosphatase, Body Weight, Organic Chemistry, Dose-Response Relationship, Radiation, AKT, protein kinase B (PKB), a serine/threonine-specific protein kinase, ONOO−, peroxynitrite, MnTnHex-2-PyP5+, Mn(III) meso-tetrakis(N-(n-hexyl)pyridinium-2-yl)porphyrin (AEOL10113), Porphyrin, Fischer rats, Rats, Inbred F344, Rats, Staining, Manganese porphyrins, chemistry, lcsh:Biology (General), MnP, Mn porphyrin, MnTE-2-PyP5+, NHE, normal hydrogen electrode, TGF-β1, one of the 3 members of the TGF-β transforming growth factor-β family, SAH, subarachnoid hemorrhage, Oxidative stress
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المؤلفون: Schrammel, Astrid, Mussbacher, Marion, Winkler, Sarah, Haemmerle, Guenter, Stessel, Heike, Wölkart, Gerald, Zechner, Rudolf, Mayer, Bernd
المصدر: Biochimica et Biophysica Acta
مصطلحات موضوعية: pVASP, phosphorylated vasodilator-stimulated phosphoprotein, Mac-2, galectin-3, MnTBAP, Mn(III)tetrakis (4-benzoic acid) porphyrin chloride, Blotting, Western, PBS, phosphate-buffered saline, nNOS, neuronal nitric oxide synthase, (s)GC, (soluble) guanylate cyclase, Adipose triglyceride lipase, Models, Biological, Article, Lipid Metabolism, Inborn Errors, Mice, Muscular Diseases, SOD, superoxide dismutase, FFA, free fatty acid, PKC, protein kinase C, Animals, Molecular Biology, ATGL(−/−), adipose triglyceride lipase knockout, DEA/NO, 2,2-diethyl-1-nitroso-oxyhydrazine, Inflammation, ATGL, adipose triglyceride lipase, NO, nitric oxide, BH4, tetrahydrobiopterin, [(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(1H)-one], NADPH oxidase, Myocardium, BH2, dihydrobiopterin, [2-amino-6-(1,2-dihydroxypropyl)-7,8-dihydro-1H-pteridin-4-one], eNOS, endothelial nitric oxide synthase, Lipase, Cell Biology, NADPH, nicotinamide adenine dinucleotide phosphate, Ichthyosiform Erythroderma, Congenital, MCP-1, monocyte chemotactic protein-1, NOX, NADPH oxidase, ONOO−, peroxynitrite, Mice, Mutant Strains, TG, triacylglycerol, TNFα, tumor necrosis factor α, IL-6, interleukin 6, Cardiac hypertrophy, Disease Models, Animal, Oxidative Stress, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, iNOS, inducible nitric oxide synthase, PPARα, peroxisome proliferator receptor α, DAG, diacylglycerol, VASP, vasodilator-stimulated phosphoprotein
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المؤلفون: Steven Bozinovski, Ross Vlahos
المصدر: Clinical Science (London, England : 1979)
مصطلحات موضوعية: Pathology, PDE, phosphodiesterase, V/Q, ventilation/perfusion, Drug Evaluation, Preclinical, HDAC, histone deacetylation, Review Article, Disease, medicine.disease_cause, Bioinformatics, TNF-α, tumour necrosis factor-α, Mice, Pulmonary Disease, Chronic Obstructive, Fibrosis, Medicine, chronic obstructive pulmonary disease (COPD), Cause of death, COPD, AECOPD, acute exacerbations of COPD, General Medicine, MCP-1, monocyte chemotactic protein-1, Pathophysiology, MMP, matrix metalloproteinase, emphysema, medicine.anatomical_structure, skeletal muscle wasting, BAL, bronchoalveolar lavage, NF-κB, nuclear factor κB, medicine.symptom, PI3K, phosphoinositide 3-kinase, medicine.medical_specialty, LTB4, leukotriene B4, GOLD, Global initiative on chronic Obstructive Lung Disease, acute exacerbations of chronic obstructive pulmonary disease (AECOPD), Inflammation, S8, smoking, ROS, reactive oxygen species, SOD, superoxide dismutase, TGF-β, transforming growth factor-β, Gpx, glutathione peroxidase, TIMP, tissue inhibitor of metalloproteinases, Animals, Humans, NE, neutrophil elastase, SLPI, secretory leucocyte protease inhibitor, Lung, business.industry, medicine.disease, ONOO−, peroxynitrite, RV, rhinovirus, IL, interleukin, respiratory tract diseases, Disease Models, Animal, Oxidative Stress, GM-CSF, granulocyte/macrophage colony-stimulating factor, COPD, chronic obstructive pulmonary disease, Nrf2, nuclear erythroid-related factor 2, O2•−, superoxide radical, BALF, BAL fluid, business, MAPK, mitogen-activated protein kinase, Oxidative stress
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المؤلفون: Yoshio Kodera, Tsuneo Takenaka, Pamela K. Carmines, Yoshikazu Aoki, Masanori Yokoba, Tadakazu Maeda, Naohito Ishii, Masato Katagiri, Masamichi Oh-Ishi, Tsuyoshi Ichikawa, Hiroyuki Imaizumi, Hideki Ikenagasa
المصدر: Clinical Science (London, England : 1979)
مصطلحات موضوعية: BP, blood pressure, Male, Angiotensin-Converting Enzyme Inhibitors, STZ+ENAL, enalapril-treated STZ rats, urologic and male genital diseases, ACEi, angiotensin-converting enzyme inhibitor(s), Rats, Sprague-Dawley, chemistry.chemical_compound, DM, diabetes mellitus, MS/MS, tandem MS, 3-NT, 3-nitrotyrosine, oxidative stress, MMSDH, methylmalonate-semialdehyde dehydrogenase, biology, LC, liquid chromatography, 2-DE, two-dimensional gel electrophoresis, Chemistry, Superoxide, ACO2, General Medicine, proteomic analysis, NOx, nitrate+nitrite, medicine.anatomical_structure, Glutamate dehydrogenase 1, NNA, Nω-nitro-L-arginine, Sham+ENAL, enalapril-treated Sham rats, medicine.drug, GDH1, glutamate dehydrogenase 1, medicine.medical_specialty, Kidney Cortex, Renal cortex, TCA, tricarboxylic acid, S6, Peptidyl-Dipeptidase A, STZ, streptozotocin, S4, ACO2, aconitase 2, Mitochondrial Proteins, Superoxide dismutase, DN, diabetic nephropathy, nitric oxide, SOD, superoxide dismutase, Internal medicine, medicine, Animals, Humans, Enalapril, 3-nitrotyrosine, Original Paper, NO, nitric oxide, NBT, Nitro Blue Tetrazolium, diabetic nephropathy, GFR, glomerular filtration rate, HBSS, Hank’s balanced salt solution, Angiotensin-converting enzyme, Streptozotocin, O2−, superoxide anion, ONOO−, peroxynitrite, Rats, Disease Models, Animal, Diabetes Mellitus, Type 1, Endocrinology, biology.protein, PEPCK, phosphoenolpyruvate carboxykinase, Tyrosine
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المؤلفون: Keyvan Karimi Galougahi, Edwin Ho, Gemma A. Figtree, Ravi Bhindi, Chia-Chi Liu
المصدر: Redox Biology, Vol 1, Iss 1, Pp 483-491 (2013)
Redox Biologyمصطلحات موضوعية: Pathology, Biomedical Research, Clinical Biochemistry, HOCl, hypochlorous acid, MPO, myeloperoxidase, Review Article, Disease, Bioinformatics, medicine.disease_cause, Biochemistry, lcsh:QH301-705.5, chemistry.chemical_classification, lcsh:R5-920, Glutathionylation, Cardiovascular disease, Prognosis, HO2•, hydroperoxyl radical, Cardiovascular Diseases, H2O2, hydrogen peroxide, Biomarker (medicine), lcsh:Medicine (General), NO2, nitrogen dioxide, medicine.medical_specialty, GSH, glutathione (reduced), Cardiovascular research, Oxidative phosphorylation, CVD, cardiovascular disease, OxLDL, Oxidized low-density lipoprotein, IsoP, isoprostane, ROS, reactive oxygen species, Mediator, Disease severity, medicine, Animals, Humans, MDA, malondialdehyde, Reactive oxygen species, •OH, hydroxyl radical, business.industry, Organic Chemistry, Biomarker, ONOO−, peroxynitrite, chemistry, lcsh:Biology (General), Oxidative stress, business, TBARS, thiobarbituric acid reacting substance, Biomarkers, O2•−, superoxide
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المؤلفون: Balaraman Kalyanaraman
المصدر: Redox Biology
Redox Biology, Vol 1, Iss 1, Pp 244-257 (2013)مصطلحات موضوعية: LOOH, lipid hydroperoxide, Clinical Biochemistry, HOCl, hypochlorous acid, MPO, myeloperoxidase, CO3–, carbonate radical, CO2, carbon dioxide, Biochemistry, Antioxidants, Peroxynitrite, chemistry.chemical_compound, GTP, guanosine triphosphate, LDL, low-density lipoprotein, GSH, glutathione, Disease, Cu2+, cupric ion, eNOS, endothelial nitric oxide synthase or NOS-3, Hydrogen peroxide, lcsh:QH301-705.5, sGC, soluble guanylyl cyclase, 8-OHdG, 8-hydroxy-2-deoxyguanosine, chemistry.chemical_classification, lcsh:R5-920, GPx, glutathione peroxidase, Superoxide, Oxidants, Graphical Review, NOX, NADPH oxidase, Reactive Nitrogen Species, Keap1, Kelch-like ECH-associated protein 1, Reperfusion injury, OS, oxidative stress, PDT, photodynamic therapy, H2O2, hydrogen peroxide, lcsh:Medicine (General), IC, intersystem crossing, Oxidation-Reduction, ATP, adenosine triphosphate, EDRF, endothelial-derived relaxing factor, O2•–, superoxide, ONOOH, peroxynitrous acid, Context (language use), iNOS, inducible nitric oxide synthase or NOS-2, Redox, GSSG, oxidized glutathione disulfide, nNOS, neuronal nitric oxide synthase or NOS-1, ONOOCO2−, nitrosoperoxycarbonate, RNS, reactive nitrogen species, NOS, •NO synthase, ROS, reactive oxygen species, SOD, superoxide dismutase, Detoxification, medicine, Humans, Education, Graduate, MnSOD, manganese superoxide dismutase, •NO, nitric oxide, Reactive nitrogen species, XO, xanthine oxidase, Reactive oxygen species, •OH, hydroxyl radical, cGMP, cyclic GMP, CKD, chronic kidney disease, Organic Chemistry, BH4, tetrahydrobiopterin, CGD, chronic granulomatous disease, medicine.disease, DOX, doxorubicin, ONOO−, peroxynitrite, LOO•, lipid peroxy radical, XD, xanthine dehydrogenase, MC540, merocyanine 540, lcsh:Biology (General), chemistry, 4-HNE, hydroxynonenol, CAT, catalase, Clinical Medicine
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المؤلفون: Subramaniam Pennathur, Daryl M. Okamura
المصدر: Redox Biology
مصطلحات موضوعية: Antioxidant, medicine.medical_treatment, Clinical Biochemistry, HOCl, hypochlorous acid, MPO, myeloperoxidase, Review Article, medicine.disease_cause, Kidney, AGEs, advanced glycation end-products, Biochemistry, LDL, low density lipoprotein, Fibrosis, Chronic kidney disease, O2•−, superoxide anion, chemistry.chemical_classification, HODE, hydroxyoctadecadienoic acid, Chemistry, eNOS, endothelial nitric oxide synthase, 3. Good health, medicine.anatomical_structure, ESRD, end stage renal disease, H2O2, hydrogen peroxide, CML, Nε-(carboxymethyl)lysine, medicine.symptom, Signal transduction, RNase, ribonuclease, Oxidation-Reduction, medicine.medical_specialty, Oxidized amino acids, Inflammation, Internal medicine, NO2•, nitrogen dioxide, PUFA, polyunsaturated fatty acid, medicine, Animals, Humans, ALE, advanced lipoxidation end-products, NOX, NAD(P)H oxidase, Renal Insufficiency, Chronic, Reactive oxygen species, Mass spectrometry, RAGE, Receptor for AGE, Organic Chemistry, BH4, tetrahydrobiopterin, medicine.disease, ONOO−, peroxynitrite, HO•, hydroxyl radical, Oxidative Stress, Endocrinology, MS, mass spectrometry, NEFA, non esterified fatty acid, NO•, nitric oxide, Cancer research, Reactive Oxygen Species, Oxidative stress, Kidney disease
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المصدر: Redox Biology, Vol 2, Iss C, Pp 430-435 (2014)
Redox Biologyمصطلحات موضوعية: Aging, Glycosylation, Clinical Biochemistry, Lipoxygenase, ROS, reactive nitrogen species, MPO, myeloperoxidase, Review Article, GPX, glutathione peroxidase, medicine.disease_cause, Endoplasmic Reticulum, Biochemistry, chemistry.chemical_compound, Thioredoxins, GSH, glutathione, Protein Isoforms, FX1, factor XI, Trx, thioredoxin, GRX, glutaredoxin, NOS, nitric oxide synthase, Protein maturation, lcsh:QH301-705.5, chemistry.chemical_classification, lcsh:R5-920, NADPH oxidase, PDI, protein disulphide isomerase, biology, Peroxiredoxin, Blood Proteins, Blood proteins, Reactive Nitrogen Species, NOX, NADPH oxidase, CRP, C-reactive protein, Thioredoxin, Oxidoreductases, lcsh:Medicine (General), Oxidation-Reduction, VWF, von Willebrand factor, Xanthine Oxidase, Nitration, Kupffer Cells, Nitrosation, MIRNA, microRNA, ER, endoplasmic reticulum, RNS, reactive nitrogen species, COX, cyclo-oxygenase, ERO1, endoplasmic reticulum oxidoreductin 1, Oxidation, Extracellular, medicine, Animals, Humans, GPI, glycoprotein 1, EV, extracellular vesicles, Reactive nitrogen species, Peroxidase, Reactive oxygen species, NO, nitric oxide, XO, xanthine oxidase, O2•−, superoxide anion radical, Organic Chemistry, NADPH Oxidases, BH4, tetrahydrobiopterin, Peroxiredoxins, Oxidative Stress, Ageing, chemistry, lcsh:Biology (General), biology.protein, Prx, peroxiredoxin, Nitric Oxide Synthase, Reactive Oxygen Species, Protein Processing, Post-Translational, ONOO-, peroxynitrite, Oxidative stress
وصف الملف: application/pdf
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المؤلفون: Tracy Robson, Marie M. Migaud, Claire H. Ogle, Helen O. McCarthy, David G. Hirst, Ahlam A. Ali, Jonathan A. Coulter
المصدر: Bioscience Reports
Bioscience Reports, Vol 33, Iss 2, p e00031 (2013)مصطلحات موضوعية: FeTPPs, 5,10,15,20-tetrakis(4-sulfonatophenyl)porphyrinato iron (III), TRAIL, TNF (tumour necrosis factor)-related apoptosis-inducing ligand, lcsh:Life, lcsh:QR1-502, Apoptosis, Biochemistry, lcsh:Microbiology, DMEM, Dulbecco’s modified Eagle’s medium, chemistry.chemical_compound, GR, glutathione reductase, HNO, nitroxyl, NOS, nitric oxide synthase, Cytotoxicity, HIF, hypoxia inducible factor, RSNO, S-nitrosothiols, TEMPO-9-AC [4-((9-acridinecarbonyl)amino)-2,2,6,6-tetramethylpiperidin-1-oxyl], NOX, NADPH oxidase, Glutathione, Reactive Nitrogen Species, Cell Hypoxia, Oxygen tension, Cell biology, Hypoxia-inducible factors, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, cytotoxicity, Nitrogen Oxides, Triazenes, Peroxynitrite, Signal Transduction, DAF-2DA, 4,5-diaminofluorescein-diacetate, N2O3, dinitrogen trioxide, Biophysics, Nitric Oxide, S4, Nitric oxide, RNS, reactive nitrogen species, SOD, superoxide dismutase, Cell Line, Tumor, Humans, Nitric Oxide Donors, Molecular Biology, Reactive nitrogen species, Original Paper, hypoxia, Cell Biology, S-Nitrosylation, Hypoxia-Inducible Factor 1, alpha Subunit, ONOO−, peroxynitrite, S-nitrosylation, Oxygen, lcsh:QH501-531, chemistry, DTT, dithiothreitol, Tumor Suppressor Protein p53, O2•−, superoxide