المؤلفون: Villa-Morales, María, Pérez-Gómez, Laura, Pérez Gómez, Eduardo, López-Nieva, Pilar, Fernández-Navarro, Pablo, Santos, Javier

مصطلحات موضوعية: 577.1, 577.2, T-cell acute lymphoblastic leukaemia (T-ALL), NRF2 (nuclear factor erythroid 2-related factor 2), prognostic biomarker, Ciencias, 23 Química

وصف الملف: application/pdf

Relation: https://hdl.handle.net/20.500.14352/104813; Villa-Morales, M.; Pérez-Gómez, L.; Pérez-Gómez, E.; López-Nieva, P.; Fernández-Navarro, P.; Santos, J. Identification of NRF2 Activation as a Prognostic Biomarker in T-Cell Acute Lymphoblastic Leukaemia. Int. J. Mol. Sci. 2023, 24, 10350. https://doi.org/10.3390/ijms241210350; https://doi.org/10.3390/ijms241210350; https://www.mdpi.com/1422-0067/24/12/10350

الاتاحة: https://hdl.handle.net/20.500.14352/104813
https://doi.org/10.3390/ijms241210350
https://www.mdpi.com/1422-0067/24/12/10350

المؤلفون: Christina Thanas, Panos G. Ziros, Dionysios V. Chartoumpekis, Cédric O. Renaud, Gerasimos P. Sykiotis

المصدر: Antioxidants; Volume 9; Issue 11; Pages: 1082

مصطلحات موضوعية: thyroid, Nrf2 (nuclear factor erythroid 2-related factor 2), Keap1 (Kelch-like ECH-associated protein 1), thyroglobulin, oxidative stress, goiter, antioxidant

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/antiox9111082

الاتاحة: https://doi.org/10.3390/antiox9111082

المؤلفون: Cedric O. Renaud, Panos G. Ziros, Dionysios V. Chartoumpekis, Massimo Bongiovanni, Gerasimos P. Sykiotis

المصدر: Frontiers in Endocrinology, Vol 10 (2019)

مصطلحات موضوعية: thyroid, Nrf2 (nuclear factor erythroid 2-related factor 2), Keap1 (Kelch-like ECH-associated protein 1), thyroglobulin, oxidative stress, goiter, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fendo.2019.00510/full; https://doaj.org/toc/1664-2392

URL الوصول: https://doaj.org/article/868e5804eeca46b2b28347b866639367

المؤلفون: Wenbin Huang, Lei Cai, Guolin He, Liang Zhao, Yishi Lu, Mingxin Pan, Donghui Zhang, Yuan Cheng, Hangyu Liao, Weimei Huang, Yujun Tang, Liuran Li, Kunling Chen

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 12, Pp 1227-1239 (2021)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: Sorafenib, Original article, Cancer Research, Carcinoma, Hepatocellular, Amino Acid Transport System y+, Hepatocellular carcinoma, Regulator, ABCC5, SLC7A11, urologic and male genital diseases, ROS, reactive oxygen species, In vivo, Cell Line, Tumor, GSH, glutathione, Humans, Medicine, Ferroptosis, IF, immunofluorescence, heterocyclic compounds, Protein kinase B, neoplasms, PI3K/AKT/mTOR pathway, RC254-282, biology, SLC7A11, solute carrier family 7 member 11, business.industry, 5-Fu, 5-fluorouracil, Liver Neoplasms, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, female genital diseases and pregnancy complications, digestive system diseases, ABCC5, ATP binding cassette subfamily C member 5, Drug Resistance, Neoplasm, NRF2, nuclear factor erythroid 2-related factor 2, GPx4, glutathione peroxidase 4, biology.protein, Cancer research, qRT-PCR, quantitative RT-PCR, Acquired resistance, Multidrug Resistance-Associated Proteins, HCC, hepatocellular carcinoma, business, IHC, immunohistochemistry, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7546a05995e276bc0a627d79310110
http://www.sciencedirect.com/science/article/pii/S1476558621000919

المؤلفون: Hai-Yong Chen, Yibin Feng, Cheng Zhang, Ning Wang, Sha Li, Guoyi Tang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 9, Pp 2749-2767 (2021)

مصطلحات موضوعية: LOX1, lectin-like oxidized LDL receptor 1, BUN, blood urea nitrogen, TGBM, thickness of glomerular basement membrane, NQO1, NAD(P)H:quinone oxidoreductase 1, STAT, signal transducers and activators of transcription, N/O, not observed, p62, sequestosome 1 protein, p-IRS1, phospho-IRS1, Review, NOX-4, nicotinamide adenine dinucleotide phosphate-oxidase-4, OCP, oxidative carbonyl protein, Traditional Chinese medicine, AGEs, advanced glycation end-products, N/A, not applicable, TRAF5, tumor-necrosis factor receptor-associated factor 5, Health problems, 0302 clinical medicine, ESRD, end-stage renal disease, LDL, low-density lipoprotein, BMP-7, bone morphogenetic protein-7, TGFβR-I/II, TGF-β receptor I/II, Medicine, P70S6K, 70-kDa ribosomal protein S6 kinase, General Pharmacology, Toxicology and Pharmaceutics, SOCS, suppressor of cytokine signaling proteins, HO-1, heme oxygenase-1, 0303 health sciences, TG, triglyceride, BW, body weight, HDL-C, high density lipoprotein-cholesterol, RASI, renin-angiotensin system inhibitor, ATK, protein kinase B, TBARS, thiobarbituric acid-reactive substance, BCL-XL, B-cell lymphoma-extra large, Gαq, Gq protein alpha subunit, GCK, glucokinase, PI3K, phosphatidylinositol 3 kinases, Systematic review, TLR-2/4, toll-like receptor 2/4, IR, insulin receptor, PERK, protein kinase RNA-like eukaryotic initiation factor 2A kinase, 030220 oncology & carcinogenesis, CRP, C-reactive protein, IRS, insulin receptor substrate, AM, mesangial area, JAK, Janus kinase, FBG, fasting blood glucose, ETAR, endothelium A receptor, LDL-C, low density lipoprotein-cholesterol, CD2AP, CD2-associated protein, eIF2α, eukaryotic initiation factor 2α, RM1-950, mTOR, mammalian target of rapamycin, CHOP, C/EBP homologous protein, STZ, streptozotocin, 03 medical and health sciences, ADE, adverse event, PKC, protein kinase C, LC3, microtubule-associated protein light chain 3, ORP150, 150-kDa oxygen-regulated protein, PGE2, prostaglandin E2, IL-1β/6, interleukin 1β/6, Diabetic kidney disease, IGF-1, insulin-like growth factor 1, EP, E-prostanoid receptor, FN, fibronectin, eGFR, estimated GFR, MDA, malondialdehyde, Chinese medicine, MMP-2, matrix metallopeptidase 2, XBP-1, spliced X box-binding protein 1, TGF-β, tumor growth factor β, GRB 10, growth factor receptor-bound protein 10, medicine.disease, Clinical trial, GRP78, glucose-regulated protein 78, UP, urinary protein, IGF-1R, insulin-like growth factor 1 receptor, ACEI, angiotensin-converting enzyme inhibitor, BCL-2, B-cell lymphoma 2, EMT, epithelial-to-mesenchymal transition, MAPK, mitogen-activated protein kinase, MYD88, myeloid differentiation primary response 88, PBG, postprandial blood glucose, RCT, randomized clinical trial, N/R, not reported, COL-I/IV, collagen I/IV, PINK1, PTEN-induced putative kinase 1, UACR, urinary albumin to creatinine ratio, C, control group, Diabetic nephropathy, GPX, glutathione peroxidase, ICAM-1, intercellular adhesion molecule-1, Bioinformatics, VCAM-1, vascular cell adhesion molecule-1, AMPKα, adenosine monophosphate-activated protein kinase α, DM, diabetes mellitus, TFEB, transcription factor EB, TNF-α, tumor necrosis factor α, Molecular target, IKK-β, IκB kinase β, Signaling pathway, GLUT4, glucose transporter type 4, BAX, BCL-2-associated X protein, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, PARP, poly(ADP-Ribose) polymerase, SMURF-2, SMAD ubiquitination regulatory factor 2, AREs, antioxidant response elements, MD, mean difference, SMAD, small mothers against decapentaplegic, MCP-1, monocyte chemotactic protein-1, VEGF, vascular endothelial growth factor, cAMP, cyclic adenosine monophosphate, ARB, angiotensin receptor blocker, PAI-1, plasminogen activator inhibitor-1, SMD, standard mean difference, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, IκB-α, inhibitory protein α, Herbal medicine, TCM, traditional Chinese medicine, DG, glomerular diameter, GSK-3, glycogen synthase kinase 3, SIRT1, sirtuin 1, D, duration, HbA1c, glycosylated hemoglobin, WMD, weight mean difference, CTGF, connective tissue growth factor, ER, endoplasmic reticulum, DN, diabetic nephropathy, ROS, reactive oxygen species, CCR, creatinine clearance rate, SOD, superoxide dismutase, Diabetes mellitus, PGC-1α, peroxisome proliferator-activated receptor gamma coactivator 1α, ET-1, endothelin-1, UMA, urinary microalbumin, SCr, serum creatinine, IRE-1α, inositol-requiring enzyme-1α, 030304 developmental biology, TII, tubulointerstitial injury index, RAGE, receptors of AGE, business.industry, GFR, glomerular filtration rate, PTEN, phosphatase and tensin homolog, CI, confidence interval, TC, total cholesterol, SD-rat, Sprague–Dawley rat, UAER, urinary albumin excretion rate, DKD, diabetic kidney disease, T, treatment group, Molecular targets, Therapeutics. Pharmacology, α-SMA, α smooth muscle actin, SD, standard deviation, business, DAG, diacylglycerol, GCLC, glutamate-cysteine ligase catalytic subunit, Kidney disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d8ab4193adc39b242fa3c089b4f517
https://doi.org/10.1016/j.apsb.2020.12.020

المؤلفون: Tadahito Yasuda, Hideo Baba, Takatsugu Ishimoto

المصدر: Regenerative Therapy, Vol 17, Iss, Pp 8-12 (2021)
Regenerative Therapy

مصطلحات موضوعية: 0301 basic medicine, Medicine (General), OXPHOS, oxidative phosphorylation, 0302 clinical medicine, Glycolysis, NRF2, nuclear factor erythroid 2–related factor 2, LSCs, leukemia stem cells, education.field_of_study, EVs, extracellular vesicles, mTORC1, mammalian target of rapamycin complex 1, ROS, GP6, glucose-6-phosphate, IncRNAs, long noncoding RNAs, Original Article, Stem cell, IMP2, insulin-like growth factor 2, EMT, epithelial–mesenchymal transition, ATP, adenosine triphosphate, Stromal cell, CSCs, cancer stem cells, Population, TCA, tricarboxylic acid, Biomedical Engineering, PPP, pentose phosphate pathway, FBP1, fructose-1,6-biphosphatase 1, GLUT1, glucose transporter 1, Oxidative phosphorylation, Biology, Stromal niche, Biomaterials, 03 medical and health sciences, ROS, reactive oxygen species, R5-920, Cancer stem cell, PDK1, pyruvate dehydrogenase kinase 1, medicine, education, HIF1a, hypoxia inducible factor 1a, TICs, tumor initiating stem-like cells, SOD2, superoxide dismutase 2, QH573-671, Cancer, medicine.disease, Mitochondrial OXPHOS, CD44v, CD44 variant isoform, Metabolic pathway, ALDH, aldehyde dehydrogenase, 030104 developmental biology, Cancer research, CSCs, HCC, hepatocellular carcinoma, Cytology, FAO, fatty acid oxidation, 030217 neurology & neurosurgery, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6e792e0488411d444bcff6479bbf43
https://doi.org/10.1016/j.reth.2021.01.005

المؤلفون: Ding Yuan, Chengfu Yuan, Liyue Gai, Yan Gao, Yue Shi, Yumin He, Chaoqi Liu, Xuelian Wu, Gang Zhou, Changcheng Zhang

المصدر: Journal of Ginseng Research
Journal of Ginseng Research, Vol 45, Iss 3, Pp 408-419 (2021)

مصطلحات موضوعية: 0301 basic medicine, Aging, Cys C, cystatin C, SPJ-L, low-dose of SPJ, TIMPs, tissue inhibitors of metalloproteinases, SMAD, Matrix metalloproteinase, medicine.disease_cause, TNF-α, tumor necrosis factor-α, Nrf2, nuclear factor erythroid 2-related factor 2, α-SMA, α-smooth muscle aorta, 0302 clinical medicine, Renal fibrosis, Fibrosis, HO-1, human heme oxygenase 1, TGF-β1, tumor growth factor-β1, IL-6, interleukin-6, IκB, inhibitor of NF-κB, biology, NQO1, recombinant NADH dehydrogenase quinone 1, Total saponins of panax japonicus, MCP-1, monocyte chemoattractant protein-1, ECM, extracellular matrix, UA, uric acid, SPJ-H, high-dose of SPJ, 030220 oncology & carcinogenesis, medicine.symptom, Research Article, Biotechnology, medicine.medical_specialty, SPJs, saponins from panax japonicus, ARE, antioxidant response element, Inflammation, Biochemistry, Genetics and Molecular Biology (miscellaneous), 03 medical and health sciences, Internal medicine, medicine, PJ, Panax japonicas, COX2, cyclooxygenase-2, LPO, lipid peroxides, business.industry, TGF-β1/Smad, Botany, SD, Sprague-Dawley, medicine.disease, NF-κB, nuclear factor kappa-B, 030104 developmental biology, Endocrinology, Complementary and alternative medicine, Cystatin C, QK1-989, Nrf2-ARE signaling pathways, biology.protein, MMPs, matrix metalloproteinases, β2-MG, β2-microglobulin, business, Oxidative stress, Transforming growth factor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92217cdd10e9c934df2aec2229c0abbf
https://doi.org/10.1016/j.jgr.2020.08.005

المؤلفون: Maged S. Abdel-Kader, Gamal A. Soliman, Ahmed I. Foudah, Abdulaziz S. Saeedan, Reham M. Abd-Elsalam, Hanan A. Ogaly, Rehab F. Abdel-Rahman

المصدر: Saudi Journal of Biological Sciences, Vol 28, Iss 3, Pp 1713-1722 (2021)
Saudi Journal of Biological Sciences

مصطلحات موضوعية: Nrf2, Nuclear factor erythroid 2-related factor 2, medicine.medical_treatment, medicine.disease_cause, SOD, Superoxide dismutase, Follicle-stimulating hormone, DC, Diabetic control, EDTA, Ethylenediamine tetraacetic acid, Medicine, GSH-Px, Glutathione peroxidase, lcsh:QH301-705.5, Testosterone, Diabetes, LH, Luteinizing hormone, H&E, Hematoxylin and eosin, Original Article, RT-PCR, Real time polymerase chain reaction, HO-1, Heme oxygenase-1, TST, Testosterone, General Agricultural and Biological Sciences, Luteinizing hormone, HPTLC, High-performance thin layer chromatography, medicine.medical_specialty, endocrine system, Testicular Disorder, FSH, Follicle stimulating hormone, FBG, Fasting blood glucose, HO-1, Nrf2, Artemisia judaica, GSH, Reduced glutathione, Downregulation and upregulation, LPO, Lipid peroxidation, Internal medicine, MDA, Malondialdehyde, ComputingMethodologies_COMPUTERGRAPHICS, AJ, Artemisia judaica L, business.industry, Insulin, STZ, Streptozotocin, PCNA, Proliferating cell nuclear antigen, CAT, Catalase, Endocrinology, Fertility, lcsh:Biology (General), ELISA, ELISA: Enzyme-linked immunosorbent assay, HbA1c, Glycosylated hemoglobin, business, NC, Negative control, Oxidative stress, ROS, Reactive oxygen species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cddef32683deddd75fdedb6dda4e14ed
http://www.sciencedirect.com/science/article/pii/S1319562X20306689

المؤلفون: Chang Jia, Jian Xiao, Abdullah Al Mamun, Fahad Munir, Ilma Monalisa, Kailiang Zhou, Yanqing Wu

المصدر: Journal of Advanced Research, Vol 28, Iss, Pp 97-109 (2021)
Journal of Advanced Research

مصطلحات موضوعية: 0301 basic medicine, CO, Carbon monoxide, Nrf2, Nuclear factor erythroid 2-related factor 2, IL-1β, Interleukin-1 beta, H2O2, Hydrogen peroxide, CCK-8, Cell Counting Kit-8, 0302 clinical medicine, Neuroinflammation, Medicine, LPS, Lipopolysaccharide, JOA, Japanese orthopedics association, lcsh:R5-920, Multidisciplinary, Pyroptosis, Inflammasome, GSDMD, Gasdermin D, PRRs, Pattern recognition receptors, 030220 oncology & carcinogenesis, Caspase-1, ATP, Adenosine triphosphate, DAMPs, Damage-associated molecular patterns, Signal transduction, HO-1, Heme oxygenase-1, lcsh:Medicine (General), Intracellular, ECH, Echinacoside, medicine.drug, ASC, apoptosis-associated speck-like protein, Therapeutic implications, Programmed cell death, PAMPs, Pathogen-associated molecular patterns, CORM-3, Carbon monoxide releasing molecle-3, Caspase 1, Spinal cord injury, CNS, central nervous system, Article, IL-18, Interleukin-18, 03 medical and health sciences, NLRP3, OPCs, Oligodendrocyte progenitor cells, lcsh:Science (General), ComputingMethodologies_COMPUTERGRAPHICS, DRD1, Dopamine Receptor D1, business.industry, Mechanism (biology), Cx43, Connexin 43, NLRP1, NOD-like receptor protein 1, BBG, Brilliant blue G, TLR4, Toll-like receptor 4, NF-κB, Nuclear factor-kappa B, NLRP1b, NOD-like receptor protein 1b, Gal-3, Galectin-3, AIM2, Absent in melanoma 2, IRE1, Inositol requiring enzyme 1, 030104 developmental biology, NDI, Neck data index, double stranded DNAIR, Ischemia reperfusion, si-RNA, Small interfering RNA, NLRP3, Nucleotide-binding domain-like receptor protein 3, business, Neuroscience, ROS, Reactive oxygen species, TXNIP, Thioredoxin-interacting protein, lcsh:Q1-390

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58aaa585b7dc4e7f4e03b92a67b2a015
http://www.sciencedirect.com/science/article/pii/S2090123220301880

المؤلفون: Grace L. Guo, Xiaoyun Chen, Zheng Dong, Bilon Khambu, Xiao Ming Yin, Shengmin Yan

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 973-997 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, Gut Dysbiosis, OST-β, organic solute transporter subunit-β, SQSTM1, sequestosome-1, FGF15, CK19, cytokeratin 19, Gut flora, FEX, fexaramine, SHP, small heterodimer partner, 0302 clinical medicine, ERK, extracellular signal-regulated kinase, AST, aspartate transaminase, MCA, muricholic acid, CYP8B1, cytochrome p450 family 8b1, BLU, Blu-9931, TCDCA, taurochenodeoxycholic acid, Original Research, FGFR4, fibroblast growth factor receptor 4, TBA, total bile acid, Liver injury, CA, cholic acid, biology, Bile acid, Gastroenterology, qRT-PCR, quantitative real-time polymerase chain reaction, Liver, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, NRF2, nuclear factor erythroid 2-related factor 2, BA, bile acid, 030211 gastroenterology & hepatology, TDCA, taurodeoxycholic acid, medicine.drug, medicine.medical_specialty, GM, gut microbiota, ALT, alanine transaminase, medicine.drug_class, TCA, taurocholic acid, PBS, phosphate-buffered saline, IBABP, ileal bile acid-binding protein, OST-α, organic solute transporter subunit-α, Liver Injury, ASBT (SLC10A2), apical sodium–bile acid transporter, CDCA, chenodeoxycholic acid, Bile Acids and Salts, CYP7A1, cytochrome p450 7a1, 03 medical and health sciences, FXR, farnesoid X receptor, ATG, autophagy-related gene, TUDCA, tauroursodeoxycholic acid, Internal medicine, medicine, Autophagy, BAS, bile acid sequestrants, lcsh:RC799-869, Cholestyramine, ALP, alkaline phosphatase, FGF15, fibroblast growth factor 15, SE, standard error, Hepatology, Fibroblast growth factor receptor 4, biology.organism_classification, medicine.disease, Gastrointestinal Microbiome, 030104 developmental biology, Endocrinology, DCA, deoxycholic acid, PCoA, principal coordinates analysis, BSH, bile salt hydrolase, ABX, antibiotics, TLCA, taurolithocholic acid, TMCA, tauromuricholic acid, Farnesoid X receptor, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5847c5c25a4c55b7146f469ae9e2e369
http://www.sciencedirect.com/science/article/pii/S2352345X20301740

المؤلفون: Liuyi Hao, Haibo Dong, Xinguo Sun, Zhanxiang Zhou, Ruichao Yue, Wei Guo, Wenliang Zhang, Wei Zhong

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 793-811 (2021)
Cellular and Molecular Gastroenterology and Hepatology

مصطلحات موضوعية: 0301 basic medicine, NADH, reduced nicotinamide adenine dinucleotide, Gene Expression, MPO, myeloperoxidase, Dehydrogenase, Apoptosis, AST, aspartate aminotransferase, RC799-869, Pharmacology, Nicotinamide adenine dinucleotide, AH, alcoholic hepatitis, PF, pair-fed, Liver disease, chemistry.chemical_compound, Mice, 0302 clinical medicine, PCR, polymerase chain reaction, Acetamides, Basic Helix-Loop-Helix Transcription Factors, NAD(P)H Dehydrogenase (Quinone), FFA, free fatty acids, ALD, alcohol-related liver disease, NRF2, nuclear factor erythroid 2–related factor 2, Cells, Cultured, Original Research, Liver injury, biology, Chemistry, ACD, acetaldehyde, Gastroenterology, TG, triglycerides, respiratory system, Diseases of the digestive system. Gastroenterology, Organ Specificity, Chemical and Drug Induced Liver Injury, Chronic, Gene Knockdown Techniques, AhR, aryl hydrocarbon receptor, NAD+-to-NADH Ratio, NQO1, 030211 gastroenterology & hepatology, I3C, indole-3-carbinol, Disease Susceptibility, Signal transduction, Chemical and Drug Induced Liver Injury, Oxidation-Reduction, IHC, immunohistochemistry, PBS, phosphate-buffered saline, NAD+, oxidized nicotinamide adenine dinucleotide, ADH, alcohol dehydrogenase, Immunophenotyping, 03 medical and health sciences, cDNA, complementary DNA, ROS, reactive oxygen species, 4-HNE, 4-hydroxynonenal, ALT, alanine aminotransferase, medicine, Animals, Humans, IF, immunofluorescence, AF, alcohol-fed, KD, knockdown, Hepatology, Ethanol, AhR, medicine.disease, Aryl hydrocarbon receptor, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, ALDH, aldehyde dehydrogenase, Receptors, Aryl Hydrocarbon, biology.protein, Hepatocytes, Alcohol-Related Liver Disease, NAD+ kinase, NQO1, NAD(P)H quinone dehydrogenase 1, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15d326a88be99d219c0ba4eb3ebc90e
http://www.sciencedirect.com/science/article/pii/S2352345X21001028

المؤلفون: Pingping Luo, Rui Zhang, Qian Yu, George L. Tipoe, Ming Zheng, Xiaoming Sun, Yingxia Liu, Jia Xiao, Wei Li, Hong Zhang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 3, Pp 668-679 (2021)

مصطلحات موضوعية: Alcoholic liver disease, INSR, insulin receptor, TCF/LEF, T-cell factor/lymphoid enhancer factor, AST, aspartate aminotransferase, Pharmacology, TSA, thermal shift assay, 0302 clinical medicine, WAT, white adipose tissues, HSL, hormone sensitive lipase, FFA, free fatty acids, MTT, 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, General Pharmacology, Toxicology and Pharmaceutics, NF-κB, nuclear factor kappa B, RER, respiratory exchange ratio, 0303 health sciences, LRP6, low-density lipoprotein receptor related protein 6, TNF, tumor necrosis factor, NAS, NAFLD activity score, biology, TG, triglyceride, Chemistry, NIAAA, National Institute on Alcohol Abuse and Alcoholism, Liver cell, CYP2E1, cytochrome P450 2E1, 030220 oncology & carcinogenesis, LDLR, low-density lipoprotein receptor, NRF2, nuclear factor erythroid 2-related factor 2, IRS, insulin receptor substrate, GTT, glucose tolerance test, Original Article, medicine.symptom, Safety, IRTK, insulin receptor tyrosine kinase, GSK3β, glycogen synthase kinase 3 beta, NAFLD, non-alcoholic fatty liver disease, ALD, alcoholic liver disease, SREBP-1c, sterol regulatory element-binding protein 1c, Inflammation, SPR, surface plasmon resonance, AMPK, adenosine 5′-monophosphate (AMP)-activated protein kinase, SAMC, S-allylmercaptocysteine, 03 medical and health sciences, ADIPOQ, adiponectin, Insulin resistance, ORF, open reading frame, PA, palmitate acid, ALT, alanine aminotransferase, medicine, CPT1, carnitine palmitoyltransferase I, IRS-1, GRB14, growth factor receptor-bound protein 14, Protein kinase B, 030304 developmental biology, ATGL, adipose triglyceride lipase, PPARα, peroxisome proliferator-activated receptor alpha, AKT, lcsh:RM1-950, ALDH2, aldehyde dehydrogenase 2, GSK3β, Lipid metabolism, medicine.disease, S-Allylmercaptocysteine, WT, wild-type, IL, interleukin, TC, total cholesterol, Insulin receptor, FDA, U.S. Food and Drug Administration, lcsh:Therapeutics. Pharmacology, biology.protein, NAC, N-acetyl-cysteine, Steatosis, IGF-1, insulin-like growth factors-1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71348640a2921fa24860e2b42b33f51
http://europepmc.org/articles/PMC7982498

المؤلفون: Amany A. Azouz, Amira M. Abo-Youssef, Esraa Abdel-Nassir Abdel-Razek

المصدر: Saudi Pharmaceutical Journal, Vol 28, Iss 11, Pp 1317-1325 (2020)
Saudi Pharmaceutical Journal : SPJ

مصطلحات موضوعية: 0301 basic medicine, Nrf2, Nuclear factor erythroid 2-related factor 2, Anti-oxidant defense, Bcl-2, B-cell lymphoma 2, MAPK, Mitogen-activated protein kinase, NOx, Total nitrate/nitrite, Pharmaceutical Science, Pharmacology, medicine.disease_cause, VCAM-1, vascular cell adhesion molecule-1, Anti-inflammatory response, chemistry.chemical_compound, 0302 clinical medicine, GGT, gamma-glutamyl transpeptidase, Kidney, NADPH oxidase, TNF-α, Tumor necrosis factor-alpha, biology, Chemistry, Keap1, Kelch-like ECH-associated protein 1, H & E, Hematoxylin and eosin, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Original Article, NADPH, Nicotinamide adenine dinucleotide phosphate, HO-1, Heme oxygenase-1, BUN, Blood urea nitrogen, medicine.drug, GGT inhibition, CMC, Carboxymethyl cellulose, NO, Nitric oxide, Nephrotoxicity, GSH, Reduced glutathione, 03 medical and health sciences, medicine, Amlodipine, IL-6, Interleukin-6, Cisplatin nephrotoxicity, MDA, Malondialdehyde, ComputingMethodologies_COMPUTERGRAPHICS, Cisplatin, lcsh:RM1-950, NF-κB, Nuclear factor-kappa B, Glutathione, HGF, Hepatocyte growth factor, Bax, Bcl-2-associated X protein, lcsh:Therapeutics. Pharmacology, 030104 developmental biology, Renal cell survival, Apoptosis, biology.protein, Oxidative stress, ROS, Reactive oxygen species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fef96a292ea1250b476dffc2470193e
https://doi.org/10.1016/j.jsps.2020.08.022

المؤلفون: Eunice Iyanuoluwa Oribamise, Olaposi I Omotuyi, Niyi S. Adelakun, Ojochenemi A Enejoh, Oyekanmi Nash

المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 1421-1427 (2020)

مصطلحات موضوعية: endocrine system diseases, Chromolaena odorata flavonoids (CoF), Health, Toxicology and Mutagenesis, Chromolaena odorata, ARE, Antioxidant response element, 010501 environmental sciences, Pharmacology, Toxicology, 01 natural sciences, SOD, Superoxide dismutase, Anti-oxidant, chemistry.chemical_compound, 0302 clinical medicine, CoF, Chromolaena odorata is rich in flavonoids, Blood urea nitrogen, Nrf2, Nuclear factor-erythroid 2-related factor 2, biology, Regular Article, KIM-1, KidneyInjury Molecule-1, medicine.drug, MCP-1, Monocyte chemoattractant protein 1, CRD, Committee of Centre for Research and Development, Renal function, Nephropathy, Proinflammatory cytokine, 03 medical and health sciences, QoL, Quality of life, lcsh:RA1190-1270, GPx-1, Glutathioneperoxidase, MKK-3, mitogen-activated protein kinase kinase 3, medicine, OCC, Occludin, Tight junction, 0105 earth and related environmental sciences, lcsh:Toxicology. Poisons, ComputingMethodologies_COMPUTERGRAPHICS, Creatinine, business.industry, AKI, Acute kidney injury, Glomerulosclerosis, FLVs, Flavonoids, STZ, Streptozotocin, biology.organism_classification, medicine.disease, Streptozotocin, CAT, Catalase, chemistry, Pro-inflammation, TNF-α-R, Tumour necrosis alpha receptor, business, 030217 neurology & neurosurgery, ROS, Reactive oxygen species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6e8b44d3bc3b23ff7a56b347d6d60f
http://europepmc.org/articles/PMC7578532

المؤلفون: Giovanna Bermano, Derry K. Mercer, Catherine Méplan, John E. Hesketh

المصدر: The British Journal of Nutrition
British Journal of Nutrition

مصطلحات موضوعية: 0301 basic medicine, Medicine (miscellaneous), GPX, glutathione peroxidase, Nrf2, nuclear factor erythroid 2-related factor 2, CVB, coxsackievirus B3, UPR, unfolded protein response, Interferon, Epidemiology, Severe acute respiratory syndrome coronavirus 2, Micronutrients, TXNRD, thioredoxin reductase, Letter to the Editor, COVID-19, coronavirus disease 2019, education.field_of_study, Nutrition and Dietetics, Selenoprotein S, NF-κB, nuclear factor kappa-light-chain-enhancer of activated B cells, Micronutrient, NOX, NADPH oxidase, SELENOS, selenoprotein S, Redox status, Virus Diseases, SELENOF, selenoprotein F, RNA, Viral, IV, influenza virus, Animal studies, medicine.symptom, Oxidation-Reduction, Systematic Review and Meta-Analysis, medicine.drug, medicine.medical_specialty, Population, Nutritional Status, Inflammation, Biology, SARS-CoV-2, severe acute respiratory syndrome coronavirus 2, ER, endoplasmic reticulum, 03 medical and health sciences, Selenium, ROS, reactive oxygen species, Stress, Physiological, medicine, Animals, Humans, IFN, interferon, education, 030109 nutrition & dietetics, SARS-CoV-2, MERS, Middle East respiratory syndrome, COVID-19, medicine.disease, 030104 developmental biology, Viral infection, Immunology, Middle East respiratory syndrome, biology.gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaf9f791d4be7223448b47e450803a1
http://europepmc.org/articles/PMC7503044

المؤلفون: Yajie Wen, Jiahong Sun, Panpan Chen, Wenzhou Li, Tingying Jiao, Huichang Bi, Yanying Zhou, Yixin Chen, Lihuan Guan, Pan Chen, Fan Xiaomei, Yiming Jiang, Min Huang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 89-99 (2021)

مصطلحات موضوعية: GSTα, glutathianone S-transferase α, NAPQI, N-acetyl p-benzoquinone imine, AST, aspartate aminotransferase, Pharmacology, medicine.disease_cause, BrdU, bromodeoxyuridine, CDK4, cyclin-dependent kinase 4, 0302 clinical medicine, AAV, adeno-associated virus, ECL, electrochemiluminescence, GSTμ, glutathione S-transferase μ, GSH, glutathione, General Pharmacology, Toxicology and Pharmaceutics, HO-1, heme oxygenase-1, Liver injury, 0303 health sciences, Gene knockdown, biology, LDH, lactate dehydrogenase, Chemistry, CYP450, cytochromes P450, digestive, oral, and skin physiology, SIRT6, sirtuin 6, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Hepatocyte, Sirtuin, NRF2, nuclear factor erythroid 2-related factor 2, KEAP1, Kelch-like ECH-associated protein 1, Original Article, SIRT6, DNA damage, APAP, acetaminophen, ARE, antioxidant response element, NRF2, ALT, serum alanine aminotransferase, 03 medical and health sciences, H3K9ac, histone H3 Nε-acetyl-lysines 9, CCK-8, cell counting kit-8, ROS, reactive oxygen species, ALF, acute liver failure, Dox, doxorubicin, H3K56ac, histone H3 Nε-acetyl-lysines 56, medicine, Viability assay, 030304 developmental biology, Acetaminophen, P53, CCND1, cyclin D1, lcsh:RM1-950, Hepatotoxicity, medicine.disease, BCA, bicinchoninic acid, lcsh:Therapeutics. Pharmacology, DCF, dichlorofluorescein, siRNA, small interfering RNA, biology.protein, H&E, hematoxylin and eosin, CCNA1, cyclin A1, NQO1, NAD(P)H quinone dehydrogenase 1, Co-IP, co-immunoprecipitation, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bdb116a375dde7c9f1a71079b6d0f0
http://europepmc.org/articles/PMC7838028

المؤلفون: Jephte Y. Akakpo, Qingyun Bai, Xiao Yang, Li Yang, Thomas Rülicke, Lili Ji, Kurt Zatloukal, Wen-Xing Ding, Hong-Min Ni, Hui Qian, Hartmut Jaeschke

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3791-3805 (2021)

مصطلحات موضوعية: WT, wild type, 4EBP-1, translational initiation factor 4E binding protein-1, Macrophage, S6, ribosomal protein S6 kinase, NAC, N-acetylcysteine, Mitochondrion, LC3, microtubule-associated light chain 3, GSH, glutathione, GCL, glutamate cysteine ligase, KEAP1, Kelch-like ECH-associated protein-1, General Pharmacology, Toxicology and Pharmaceutics, Liver injury, KIR, KEAP1-interacting region, medicine.diagnostic_test, biology, digestive, oral, and skin physiology, Platelet, NRF2, nuclear factor erythroid 2-related factor 2, Original Article, DILI, medicine.drug, VWF, von Willebrand factor, medicine.medical_specialty, APAP, acetaminophen, NF-κB, nuclear factor-κB, RM1-950, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, Western blot, Von Willebrand factor, AILI, APAP-induced liver injury, Internal medicine, ALT, alanine aminotransferase, medicine, Autophagy, CYP2E1, cytochrome P450 2E, KC, Kupffer cells, PI3K/AKT/mTOR pathway, NPCs, non-parenchymal cells, Coagulation, APAP-AD, APAP-adducts, KO, knockout, Cell growth, business.industry, NQO1, NADPH quinone dehydrogenase 1, Hepatotoxicity, CLEC-2, C-type lectin-like receptor, medicine.disease, Acetaminophen, Endocrinology, biology.protein, H&E, hematoxylin and eosin, Liver regeneration, Therapeutics. Pharmacology, business, NAPQI, N-acetyl-p-benzoquinone imine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822a9d722ce09297bbb1ac56b38e95ad
https://pubmed.ncbi.nlm.nih.gov/35024307

المؤلفون: Wei Xu, You Jiaojiao, Yong Chen, Yayun Liu, Ting Zhai

المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 4, Pp 745-757 (2019)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Lipid accumulation, AST, aspartate aminotransferase, HO-1, heme oxygenase 1, Pharmacology, Gpat, glycerol-3-phosphate acyltransferase, medicine.disease_cause, PI3K, phosphatidylinositol 3-hydroxy kinase, chemistry.chemical_compound, pIRS1, phosphorylation of insulin receptor substrate 1, 0302 clinical medicine, IR, insulin resistance, Pnpla3, phospholipase domain containing 3, Mttp, microsomal triglyceride transfer protein, General Pharmacology, Toxicology and Pharmaceutics, 0303 health sciences, TG, triglyceride, NASH, CYP2E1, cytochrome P450 2E1, HE, hematoxylin–eosin, CYP2E1, Fabp5, fatty acid-binding proteins 5, pJNK, phosphorylation of c-Jun N-terminal kinase, 030220 oncology & carcinogenesis, JNK, c-Jun N-terminal kinase, NRF2, nuclear factor erythroid 2-related factor 2, IRS1, insulin receptor substrate 1, NF-κB, nuclear factor κB, Pparα, peroxisome proliferator activated receptor α, NASH, nonalcoholic steatohepatitis, Original article, NAFLD, non-alcoholic fatty liver disease, GSH-Px, glutathione peroxidase, MT, Masson–Trichrome, CFLAR, caspase 8 and Fas-associated protein with death domain-like apoptosis regulator, MCS, methionine- and choline-sufficient, Silibinin, Cpt1α, carnitine palmitoyl transferase 1α, CFLAR, PA, palmitic acid, 03 medical and health sciences, In vivo, ALT, alanine aminotransferase, CYP4A, cytochrome P450 4A, medicine, Srebp-1c, sterol regulatory element binding protein-1C, Acox, acyl-coenzyme A oxidase X, Oxidation stress, 030304 developmental biology, MCD, methionine- and choline-deficient, MDA, malondialdehyde, Methionine, lcsh:RM1-950, OA, oleic acid, 2-NBDG, 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amino)-2-deoxyglucose, Lipid metabolism, Scd-1, stearoyl-coenzyme A desaturase-1, medicine.disease, TC, total cholesterol, lcsh:Therapeutics. Pharmacology, chemistry, ORO, oil red O, SD, Sprague–Dawley, CAT, catalase, Steatohepatitis, Akt, serine–threonine protein kinase, MAPK, mitogen-activated protein kinase, Oxidative stress

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e7ccc826a7d00426fc07ff24e9b917
https://doi.org/10.1016/j.apsb.2019.02.006

المؤلفون: Wen-Xing Ding, Hartmut Jaeschke, David S Umbaugh, Olamide B. Adelusi, Giselle Sanchez-Guerrero, Nga T. Nguyen, Jephte Y. Akakpo, Anup Ramachandran

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3740-3755 (2021)

مصطلحات موضوعية: GSSG, glutathione disulfide, LOOH, lipid hydroperoxides, NQO1, NAD(P)H:quinone oxidoreductase 1, TLR, toll like receptor, HNE, 4-hydroxynonenal, NAC, N-acetylcysteine, Apoptosis, Review, Bioinformatics, SMAC/DIABLO, second mitochondria-derived activator of caspase/direct inhibitor of apoptosis-binding protein with low pI, GSH, glutathione, General Pharmacology, Toxicology and Pharmaceutics, Liver injury, Innate immunity, BSO, buthionine sulfoximine, mTORC1, mammalian target of rapamycin complex 1, MCP-1, monocyte chemoattractant protein-1, Mitochondria, CYP, cytochrome P450 enzymes, GPX4, glutathione peroxidase 4, NRF2, nuclear factor erythroid 2-related factor 2, KEAP1, Kelch-like ECH-associated protein 1, LPO, lipid peroxidation, NF-κB, nuclear factor κB, medicine.drug, DMSO, dimethylsulfoxide, Inflammatory response, Gclm, glutamate–cysteine ligase modifier subunit, HMGB1, high mobility group box protein 1, APAP, acetaminophen, ARE, antioxidant response element, RM1-950, TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling, UGT, UDP-glucuronosyltransferases, Necrotic cell, MPT, mitochondrial permeability transition, Acetaminophen hepatotoxicity, NRF2, ROS, reactive oxygen species, EndoG, endonuclease G, medicine, Autophagy, Injury mechanisms, Ferroptosis, MnSOD, manganese superoxide dismutase, Antipyretic drugs, MDA, malondialdehyde, Drug metabolism, business.industry, ATG, autophagy-related genes, PUFAs, polyunsaturated fatty acids, Liver failure, medicine.disease, CAD, caspase-activated DNase, Gclc, glutamate–cysteine ligase catalytic subunit, Acetaminophen, LC3, light chain 3, AIF, apoptosis-inducing factor, AMPK, AMP-activated protein kinase, DAMPs, damage-associated molecular patterns, JNK, c-jun N-terminal kinase, Therapeutics. Pharmacology, LAMP, lysosomal-associated membrane protein, business, NAPQI, N-acetyl-p-benzoquinone imine, FSP1, ferroptosis suppressing protein 1, MAP kinase, mitogen activated protein kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bde30b76b24a28a9236a78a6ec2b0a30
https://pubmed.ncbi.nlm.nih.gov/35024303

المؤلفون: Satoko Komatsu-Hirota, Yu-shin Sou, Masaaki Komatsu, Mohammad Omar Faruk, Nobuo N. Noda, Shun Kageyama, Yoshinobu Ichimura, Afnan H. El-Gowily, Masato Koike

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: amyotrophic lateral sclerosis, autophagy, NF-E2-Related Factor 2, Mutant, Mutation, Missense, LIR, LC3-interacting region, Biochemistry, NRF2, PDB, Paget’s disease of bone, Mice, Gene expression, Sequestosome-1 Protein, NQO1, NAD(P)H dehydrogenase, quinone 1, medicine, Missense mutation, Animals, Humans, Amyotrophic lateral sclerosis, BRET, bioluminescence resonance energy transfer, NRF2, nuclear factor erythroid 2–related factor 2, Molecular Biology, Gene, Kelch-Like ECH-Associated Protein 1, Transition (genetics), Chemistry, UBA, ubiquitin-associated, Autophagy, p62, liquid droplet, KIR, Kelch-like ECH-associated protein 1–interacting region, Cell Biology, medicine.disease, ALS, amyotrophic lateral sclerosis, GSTM1, Glutathione S-transferase Mu 1, FTD, frontotemporal degeneration, Cell biology, HEK293 Cells, TRAF6, tumor necrosis factor receptor–associated factor 6, mTORC1, mechanistic target of rapamycin complex 1, UGDH, UDP-glucose 6-dehydrogenase, RBP, RNA-binding protein, Intracellular, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9984bac28fcd074c4fc72342ddc213
https://pubmed.ncbi.nlm.nih.gov/34774801