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المؤلفون: Iwao Ojima, Matthew W. Elmes, Monaf Awwa, Joseph M. Sweeney, Martin Kaczocha, Jerome Falcone, Simon Tong, Yunrong Jing, Diane Bogdan, Brian P. Ralph, Dale G. Deutsch, Joyce Che, Longfei Wei, Gregory Carbonetti, Robert C. Rizzo, Liqun Wang, Norbert Smietalo, Huilin Li, Yuchen Zhou, Kongzhen Hu, Timothy Clement, Matthew Freitag, Olivia M. Joseph, Qianwen Gan, Hao-Chi Hsu, Su Yan, Gary Y.H. Teng
المصدر: European Journal of Medicinal Chemistry. 154:233-252
مصطلحات موضوعية: Male, 0301 basic medicine, Fatty Acid-Binding Proteins, Chemical synthesis, Article, Fatty acid-binding protein, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Antinociceptive Agents, Animals, Humans, Mice, Knockout, Pharmacology, Analgesics, Dose-Response Relationship, Drug, Molecular Structure, Truxillic acid, Organic Chemistry, Esters, General Medicine, Anandamide, AutoDock, FABP7, Mice, Inbred C57BL, Molecular Docking Simulation, 030104 developmental biology, chemistry, Biochemistry, Docking (molecular), Drug Design, Computer-Aided Design, Cyclobutanes
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المؤلفون: Yong Lu, Keith M. Studholme, Iwao Ojima, Martin Kaczocha, Jerome Falcone, Diane Bogdan, Martha P. Kanjiya, Su Yan, Maria Adelaida Gomez, Michelino Puopolo, Sang Hoon Park, Gregory Carbonetti, Norbert Smietalo, Matthew W. Elmes
المصدر: The Journal of biological chemistry. 293(14)
مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, THP-1 Cells, medicine.medical_treatment, Interleukin-1beta, Immunology, Prostaglandin, Inflammation, Pharmacology, Fatty Acid-Binding Proteins, Biochemistry, Fatty acid-binding protein, Dinoprostone, Proinflammatory cytokine, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Microsomes, medicine, Animals, Humans, Prostaglandin E2, Molecular Biology, Prostaglandin-E Synthases, Mice, Knockout, biology, Chemistry, Macrophages, NF-kappa B, Cell Biology, Neoplasm Proteins, Up-Regulation, Mice, Inbred C57BL, 030104 developmental biology, Cytokine, Eicosanoid, A549 Cells, Cyclooxygenase 2, biology.protein, Cytokines, lipids (amino acids, peptides, and proteins), Cyclooxygenase, medicine.symptom, 030217 neurology & neurosurgery, medicine.drug