المؤلفون: Gurjeet Kaur, Manisha Prajapat, Harvinder Singh, Phulen sarma, Sanjay kumar Bhadada, Nishant Shekhar, Saurabh Sharma, Shweta Sinha, Subodh kumar, Ajay Prakash, Bikash Medhi

المصدر: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/f56c1979ed3246f2af3786d009ae6bfc

المؤلفون: Subodh Kumar, Harvinder Singh, Manisha Prajapat, Phulen Sarma, Anusuya Bhattacharyya, Hardeep Kaur, Gurjeet Kaur, Nishant Shekhar, Karanveer Kaushal, Kalpna Kumari, Seema Bansal, Saniya Mahendiratta, Arushi Chauhan, Ashutosh Singh, Rahul Soloman Singh, Saurabh Sharma, Prasad Thota, Pramod Avti, Ajay Prakash, Anurag Kuhad, Bikash Medhi

المصدر: Bioinformatics and Biology Insights, Vol 17 (2023)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1177-9322

URL الوصول: https://doaj.org/article/2c0327e2c57741fabb747521630aafd2

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

المصدر: PLoS ONE, Vol 18, Iss 11 (2023)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10627473/?tool=EBI; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/15913059ba8448fe8a955236b29334c0

المؤلفون: Anupam Raja, Nishant Shekhar, Harvinder Singh, Ajay Prakash, Bikash Medhi

المصدر: PLoS ONE, Vol 17, Iss 7, p e0268139 (2022)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/fbd6f5d84a544331a98ce4133c7033a7

المؤلفون: Manisha Prajapat, Phulen Sarma, Nishant Shekhar, Hardeep Kaur, Sanjay Singh, Subodh Kumar, Harpinder Kaur, Saniya Mahendiratta, Amit Raj Sharma, Sukhmandeep Kaur, Vidya M Mahalmani, Bikash Medhi

المصدر: Journal of Advanced Pharmaceutical Technology & Research, Vol 11, Iss 4, Pp 194-201 (2020)

مصطلحات موضوعية: glycogen synthase kinase 3 beta, in silico, molecular docking, molecular dynamics, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.japtr.org/article.asp?issn=2231-4040;year=2020;volume=11;issue=4;spage=194;epage=201;aulast=Prajapat; https://doaj.org/toc/2231-4040; https://doaj.org/toc/0976-2094

URL الوصول: https://doaj.org/article/e4c4b27ebcea40d7943279a08faa033e

المؤلفون: Nishant Shekhar, Phulen Sarma, Manisha Prajapat, Pramod Avti, Hardeep Kaur, Anupam Raja, Harvinder Singh, Anusuya Bhattacharya, Saurabh Sharma, Subodh Kumar, Ajay Prakash, Bikash Medhi

المصدر: mSystems, Vol 5, Iss 5 (2020)

مصطلحات موضوعية: severe acute respiratory syndrome coronavirus 2, fusion peptide, molecular dynamics simulation, molecular mechanics/generalized Born model and solvent accessibility, S2 fusion peptide-containing domain, coronavirus, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2379-5077

URL الوصول: https://doaj.org/article/fc81ab84c980417386b1d92ad1e80a48

المؤلفون: Singh, Jaya, Pavan Kotha, Bhojani, Neha, Nishant Shekhar, Mayur Saini, Pandey, Juhi, Ruthvik Bobba

الاتاحة: https://dx.doi.org/10.13140/rg.2.2.29474.85449
https://rgdoi.net/10.13140/RG.2.2.29474.85449

المؤلفون: Arushi Chauhan (11667535), Pramod K. Avti (327018), Nishant Shekhar (8855216), Manisha Prajapat (8688486), Phulen Sarma (8688480), Namrata Sangwan (11667538), Jitender Singh (595478), Anusuya Bhattacharyya (11667541), Subodh Kumar (1597564), Hardeep Kaur (721458), Saurabh Sharma (281820), Ajay Prakash (8688492), Bikash Medhi (3908917)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Pharmacology, Immunology, Hematology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Dimer structural integrity, molecular dynamics simulations (MD), nucleocapsid C terminal domain, radius of gyration (Rgyr), severe acute respiratory syndrome coronavirus 2 (SARS CoV-2)

Relation: https://figshare.com/articles/journal_contribution/An_insight_into_the_simulation_directed_understanding_of_the_mechanism_in_SARS_CoV-2_N-CTD_dimer_integrity_and_RNA-binding_Identifying_potential_antiviral_inhibitors/16961674

الاتاحة: https://doi.org/10.6084/m9.figshare.16961674.v1

المؤلفون: Lipika Singhal, Swati Kaushik, Rajendra Kumar Panda, Yashpal Singh Malik, Rahul K Verma, Deepa Ghosh, Navdeep Singh, Paviter Kaur, Priyam Batra, Siddhant Khare, Vipul Thakur, Rajesh Kumar, Nishant Shekhar, Surajit Chakraborty, Shalmoli Bhattacharya, Inderjeet Singh, Karan Vasisht, Ashish Sharma, Kanwar Arshjot Singh, Vikas Gautam

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5b759c3033ea3577e193902b67279178
https://doi.org/10.21203/rs.3.rs-2885471/v1

المؤلفون: Anusuya Bhattacharyya, Bikash Medhi, Nishant Shekhar, Subodh Kumar, Saurabh Sharma, Hardeep Kaur, Arushi Chauhan, Pramod Avti, Jitender Singh, Ajay Prakash, Manisha Prajapat, Namrata Sangwan, Phulen Sarma

المصدر: Journal of Biomolecular Structure and Dynamics. 40:13912-13924

مصطلحات موضوعية: Polymers, Stereochemistry, Dimer, Molecular Dynamics Simulation, Severe Acute Respiratory Syndrome, medicine.disease_cause, Antiviral Agents, chemistry.chemical_compound, Structural Biology, Mole, medicine, Humans, Computer Simulation, Molecular Biology, Coronavirus, SARS-CoV-2, COVID-19, RNA, General Medicine, In vitro, Molecular Docking Simulation, chemistry, Viral replication, Docking (molecular), CTD

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186b9a9affdfa447e6dd2088f58d8bc4
https://doi.org/10.1080/07391102.2021.1996463

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Cell_culture_and_amastigote_assay_workflow-_THP_1_monocyte_were_cultured_and_passaged_every_alternate_day_for_drug_testing_experiments_Day_1_500_l_of_THP_1_PMA_treated_cells_were_inoculated_in_chamber_slide_for_24_hours_at_37_C_for_differen/24513815

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g001
https://figshare.com/articles/figure/Cell_culture_and_amastigote_assay_workflow-_THP_1_monocyte_were_cultured_and_passaged_every_alternate_day_for_drug_testing_experiments_Day_1_500_l_of_THP_1_PMA_treated_cells_were_inoculated_in_chamber_slide_for_24_hours_at_37_C_for_differen/24513815

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Farnesol_cytotoxicity_assay_on_THP_1_macrophages_showing_percentage_viability_of_macrophages_against_different_drug_concentrations_/24513824

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g004
https://figshare.com/articles/figure/Farnesol_cytotoxicity_assay_on_THP_1_macrophages_showing_percentage_viability_of_macrophages_against_different_drug_concentrations_/24513824

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Fig_3_-/24513821

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g003
https://figshare.com/articles/figure/Fig_3_-/24513821

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Fig_2_-/24513818

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g002
https://figshare.com/articles/figure/Fig_2_-/24513818

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Fig_5_-/24513827

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g005
https://figshare.com/articles/figure/Fig_5_-/24513827

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Combination_therapy_of_Farnesol_Paromomycin_on_i_L_i_i_major_i_promastigotes_The_graph_shows_that_Paromomycin_and_Farnesol_capped_each_other_s_killing_activity_as_they_displayed_normal_killing_effects_when_treated_separately_with_Farnesol_a/24513830

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g006
https://figshare.com/articles/figure/Combination_therapy_of_Farnesol_Paromomycin_on_i_L_i_i_major_i_promastigotes_The_graph_shows_that_Paromomycin_and_Farnesol_capped_each_other_s_killing_activity_as_they_displayed_normal_killing_effects_when_treated_separately_with_Farnesol_a/24513830

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Fig_8_-/24513836

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g008
https://figshare.com/articles/figure/Fig_8_-/24513836

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/figure/Ergosterol_synthesis_pathway_and_the_3_key_inhibitors_chosen_for_the_study_26_/24513833

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.g007
https://figshare.com/articles/figure/Ergosterol_synthesis_pathway_and_the_3_key_inhibitors_chosen_for_the_study_26_/24513833

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/dataset/The_table_shows_mean_promastigote_viability_after_drug_treatment_at_various_drug_concentrations_-_No_live_promastigotes_observed_under_light_microscope_/24513839

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.t001
https://figshare.com/articles/dataset/The_table_shows_mean_promastigote_viability_after_drug_treatment_at_various_drug_concentrations_-_No_live_promastigotes_observed_under_light_microscope_/24513839

المؤلفون: Harshita Sharma, Rakesh Sehgal, Nishant Shekhar, Gaurav Shoeran, Upninder Kaur, Bikash Medhi

مصطلحات موضوعية: Biochemistry, Medicine, Microbiology, Cell Biology, Molecular Biology, Pharmacology, Cancer, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, ligand_binding analyses indicated, female phlebotomine sandflies, ergosterol synthesis pathway, ergosterol synthesis machinery, div >< p, attributes suggesting inhibition, conventional synthetic compounds, flow cytometry reveal, leishmania major <, flow cytometry, leishmania major, major <, leishmania <, conventional drugs, vitro <, silico <, l <, zoonotic cl, therapeutic potential, terminal enzyme

Relation: https://figshare.com/articles/dataset/Amastigote_assay_Table_showing_the_mean_no_of_amastigotes_per_100_macrophages_and_the_percentage_of_Macrophages_infected_after_addition_of_drugs_at_different_concentrations_for_72_hours_/24513842

الاتاحة: https://doi.org/10.1371/journal.pone.0293290.t002
https://figshare.com/articles/dataset/Amastigote_assay_Table_showing_the_mean_no_of_amastigotes_per_100_macrophages_and_the_percentage_of_Macrophages_infected_after_addition_of_drugs_at_different_concentrations_for_72_hours_/24513842