المؤلفون: Mingliang Lin, Lisa M. Eubanks, Nishant M. Karadkhelkar, Steven Blake, Kim D. Janda

المصدر: ACS Pharmacology & Translational Science. 6:802-811

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cd529a2b91afd46d9417e31165c83ea5
https://doi.org/10.1021/acsptsci.3c00031

المؤلفون: Pranav Gupta, Hai-Ling Gao, Yunali V. Ashar, Nishant M. Karadkhelkar, Sabesan Yoganathan, Zhe-Sheng Chen

المصدر: International Journal of Molecular Sciences; Volume 20; Issue 2; Pages: 268

مصطلحات موضوعية: ciprofloxacin, ABCB1 transporter, paclitaxel, multidrug-resistance

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Toxicology; https://dx.doi.org/10.3390/ijms20020268

الاتاحة: https://doi.org/10.3390/ijms20020268

المؤلفون: Sean M. Cahill, Courtney N. Niland, Agnidipta Ghosh, Nishant M. Karadkhelkar, Vern L. Schramm

المصدر: J Am Chem Soc

مصطلحات موضوعية: Stereochemistry, Crystal structure, Crystallography, X-Ray, Biochemistry, Pyrophosphate, Article, Catalysis, chemistry.chemical_compound, Hydrolysis, Colloid and Surface Chemistry, Nucleophile, Polyphosphates, Catalytic Domain, Humans, Chemistry, Leaving group, Water, Methionine Adenosyltransferase, General Chemistry, Phosphate, Malonate, Models, Chemical, Biocatalysis, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7733a0a7bf0eb56842029b613c7d8cd0
https://doi.org/10.1021/jacs.1c09328

المؤلفون: Agnidipta Ghosh (4825569), Courtney N. Niland (10225379), Sean M. Cahill (2336179), Nishant M. Karadkhelkar (11586280), Vern L. Schramm (198355)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Inorganic Chemistry, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, approximately 2 å, state reconstruction predicts, symmetric nucleophilic displacement, crystallographic analysis reveals, phosphoryl leaving group, departing phosphoryl group, modeled transition state, loose transition state, 0 , state analysis, nucleophilic water, water nucleophile, transfer reactions, product release, nmr demonstrates, malonate filling, kinetic studies, crystal structures, catalytic site, catalytic geometry, >- adenosyl

Relation: https://figshare.com/articles/journal_contribution/Mechanism_of_Triphosphate_Hydrolysis_by_Human_MAT2A_at_1_07_Resolution/16837843

الاتاحة: https://doi.org/10.1021/jacs.1c09328.s001