المؤلفون: Steven W. Jin, Nirmin Alsahafi, Xiaomei T. Kuang, Shayda A. Swann, Mako Toyoda, Heinrich Göttlinger, Bruce D. Walker, Takamasa Ueno, Andrés Finzi, Zabrina L. Brumme, Mark A. Brockman

المصدر: Cell Reports, Vol 29, Iss 6, Pp 1449-1457.e5 (2019)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719313002; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/165b49a277584f7aa63f416ef63bfe38

المؤلفون: Jonathan Richard, Beatriz Pacheco, Neelakshi Gohain, Maxime Veillette, Shilei Ding, Nirmin Alsahafi, William D. Tolbert, Jérémie Prévost, Jean-Philippe Chapleau, Mathieu Coutu, Manxue Jia, Nathalie Brassard, Jongwoo Park, Joel R. Courter, Bruno Melillo, Loïc Martin, Cécile Tremblay, Beatrice H. Hahn, Daniel E. Kaufmann, Xueling Wu, Amos B. Smith III, Joseph Sodroski, Marzena Pazgier, Andrés Finzi

المصدر: EBioMedicine, Vol 12, Iss C, Pp 208-218 (2016)

مصطلحات موضوعية: HIV-1, Envelope glycoproteins, CD4, Non-neutralizing antibodies, ADCC, CD4-mimetics, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396416304121; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/ee6c30dcd51740f589ceca78a336e2ea

المؤلفون: Jonathan Richard, Maxime Veillette, Shilei Ding, Daria Zoubchenok, Nirmin Alsahafi, Mathieu Coutu, Nathalie Brassard, Jongwoo Park, Joel R. Courter, Bruno Melillo, Amos B. Smith III, George M. Shaw, Beatrice H. Hahn, Joseph Sodroski, Daniel E. Kaufmann, Andrés Finzi

المصدر: EBioMedicine, Vol 3, Iss C, Pp 122-134 (2016)

مصطلحات موضوعية: HIV-1, Envelope glycoproteins, gp120, CD4, CD4-bound conformation, Non-neutralizing antibodies, ADCC, CD4-mimetics, Bystander killing, Medicine, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396415302383; https://doaj.org/toc/2352-3964

URL الوصول: https://doaj.org/article/cfaf156d6da54776b9c398895534db11

المؤلفون: Nirmin Alsahafi, Olfa Debbeche, Joseph Sodroski, Andrés Finzi

المصدر: PLoS ONE, Vol 10, Iss 4, p e0122111 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4388519?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/251e335f37914d188baba4c734db2d76

المؤلفون: Bethany L. MacLeod, W. Xu, Giselle Boukhaled, Sabelo Lukhele, Diala Abd-Rabbo, Mengdi Guo, Laura M. Snell, Sara Nejat, Heidi Elsaesser, Tracy L. McGaha, Slava Epelman, Kebria Hezaveh, David G. Brooks, Ramanandan Prabhakaran, Nirmin Alsahafi

المصدر: Nature Immunology. 22:1524-1537

مصطلحات موضوعية: T cell, Immunology, Cell, Biology, Blockade, Cell biology, Chronic infection, medicine.anatomical_structure, Immunity, Interferon, PD-L1, biology.protein, medicine, Immunology and Allergy, Cytotoxic T cell, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4003e48e6cfcf2bf99d001784cba3781
https://doi.org/10.1038/s41590-021-01060-7

المؤلفون: Heinrich G. Göttlinger, Mark A. Brockman, Bruce D. Walker, Zabrina L. Brumme, Shayda A. Swann, Steven W. Jin, Takamasa Ueno, Xiaomei T. Kuang, Nirmin Alsahafi, Mako Toyoda, Andrés Finzi

المصدر: Cell Reports, Vol 29, Iss 6, Pp 1449-1457.e5 (2019)
Cell reports

مصطلحات موضوعية: 0301 basic medicine, T-Lymphocytes, Viral pathogenesis, viruses, Human immunodeficiency virus (HIV), Down-Regulation, HIV Infections, Biology, Virus Replication, medicine.disease_cause, Article, General Biochemistry, Genetics and Molecular Biology, Gene Knockout Techniques, 03 medical and health sciences, 0302 clinical medicine, Downregulation and upregulation, Cell Line, Tumor, medicine, Humans, nef Gene Products, Human Immunodeficiency Virus, Allele, lcsh:QH301-705.5, Alleles, Host restriction, Infectivity, Polymorphism, Genetic, HLA-A Antigens, Virulence, Virion, Membrane Proteins, virus diseases, Virus Internalization, Virology, 3. Good health, CTL, 030104 developmental biology, lcsh:Biology (General), CD4 Antigens, Host-Pathogen Interactions, Mutation, HIV-1, 030217 neurology & neurosurgery, Function (biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2353b482383a5baa7eb947651f764a02
http://www.sciencedirect.com/science/article/pii/S2211124719313002

المؤلفون: Peter D. Kwong, Brennan P. Carman, Andrés Finzi, Dongjun Peng, Walther Mothes, Daniel S. Terry, Joseph Sodroski, Amos B. Smith, Baoshan Zhang, Cameron F. Abrams, Jason Gorman, Michael Farzan, Nick Reichard, Maolin Lu, Utz Ermel, Tongqing Zhou, Luis R. Castillo-Menendez, Akihiro Sugawara, Kevin Wang, Jonathan R. Grover, James Arthos, Scott C. Blanchard, James B. Munro, Michael Chambers, Adrian B. McDermott, Ivana Nikić-Spiegel, Edward A. Lemke, Xiaochu Ma, Matthew R. Gardner, Nirmin Alsahafi

المصدر: Nature

مصطلحات موضوعية: 0301 basic medicine, chemistry.chemical_classification, Mutation, Multidisciplinary, 030102 biochemistry & molecular biology, Strain (chemistry), viruses, HEK 293 cells, virus diseases, Trimer, medicine.disease_cause, Article, Virus, 3. Good health, 03 medical and health sciences, 030104 developmental biology, Förster resonance energy transfer, Protein structure, chemistry, Biophysics, medicine, Glycoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66785f30afa4ad33e5181894467368c
https://doi.org/10.1038/s41586-019-1101-y

المؤلفون: Laura M, Snell, Wenxi, Xu, Diala, Abd-Rabbo, Giselle, Boukhaled, Mengdi, Guo, Bethany L, Macleod, Heidi J, Elsaesser, Kebria, Hezaveh, Nirmin, Alsahafi, Sabelo, Lukhele, Sara, Nejat, Ramanandan, Prabhakaran, Slava, Epelman, Tracy L, McGaha, David G, Brooks

المصدر: Nat Immunol

مصطلحات موضوعية: Cytotoxicity, Immunologic, Programmed Cell Death 1 Receptor, Receptors, Antigen, T-Cell, Lymphocytic Choriomeningitis, Th1 Cells, Lymphocyte Activation, Adoptive Transfer, B7-H1 Antigen, Article, Mice, Inbred C57BL, Disease Models, Animal, Phenotype, Chronic Disease, Animals, Cytokines, Lymphocytic choriomeningitis virus, Female, Gene Regulatory Networks, Transcriptome, Immune Checkpoint Inhibitors, Cell Proliferation, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::828b63e1cb80f691d1a66c712b315fa5
https://pubmed.ncbi.nlm.nih.gov/34795443

المؤلفون: Jonathan Richard, Shilei Ding, Nirmin Alsahafi, Jérémie Prévost, Andrés Finzi

المصدر: Trends in Microbiology. 26:253-265

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, Microbiology (medical), Protein Conformation, viruses, Human Immunodeficiency Virus Proteins, Human immunodeficiency virus (HIV), Epitopes, T-Lymphocyte, HIV Infections, Ligands, medicine.disease_cause, Hiv 1 envelope, Microbiology, 03 medical and health sciences, Antigen, Virology, medicine, Viral Regulatory and Accessory Proteins, Cell-mediated cytotoxicity, chemistry.chemical_classification, Antibody-dependent cell-mediated cytotoxicity, 030102 biochemistry & molecular biology, biology, Antibody-Dependent Cell Cytotoxicity, env Gene Products, Human Immunodeficiency Virus, virus diseases, Antibodies, Neutralizing, In vitro, 3. Good health, 030104 developmental biology, Infectious Diseases, chemistry, NK Cell Lectin-Like Receptor Subfamily K, HIV-1, biology.protein, Antibody, Glycoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2846d6ca0f51a0a5e048a991a3d502d4
https://doi.org/10.1016/j.tim.2017.10.007

المؤلفون: Marta Massanella, Jonathan Richard, Nirmin Alsahafi, Daniel Kaufmann, Nicolas Chomont, Filippos Porichis, Amy E. Baxter, Jean-Pierre Routy, Nathalie Brassard, Julia Niessl, Rémi Fromentin, Andrés Finzi

المصدر: Nature Protocols. 12:2029-2049

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, In situ, viruses, 030106 microbiology, Human immunodeficiency virus (HIV), HIV Infections, Biology, medicine.disease_cause, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Limit of Detection, Hiv infected, medicine, Humans, RNA, Messenger, In Situ Hybridization, Fluorescence, Messenger RNA, virus diseases, RNA, Group-specific antigen, Flow Cytometry, Virology, Fusion Proteins, gag-pol, 030104 developmental biology, Flow-FISH, RNA, Viral, Antibody staining

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c60f698ba27eb09bb191ac347aad08e
https://doi.org/10.1038/nprot.2017.079

المؤلفون: Joseph Sodroski, Hanh T. Nguyen, Nirmin Alsahafi, Andrés Finzi

المصدر: Journal of Virology. 93

مصطلحات موضوعية: Antigenicity, Protein Conformation, viruses, Immunology, HIV Antibodies, HIV Envelope Protein gp120, Genes, env, Microbiology, Dithiothreitol, Virus, Structure-Activity Relationship, chemistry.chemical_compound, Retrovirus, Viral Envelope Proteins, Viral entry, Virology, Humans, Disulfides, chemistry.chemical_classification, Membrane Glycoproteins, biology, Structure and Assembly, env Gene Products, Human Immunodeficiency Virus, virus diseases, Virus Internalization, biology.organism_classification, Antibodies, Neutralizing, HIV Envelope Protein gp41, Cell biology, HEK293 Cells, chemistry, Cytoplasm, Insect Science, HIV-1, Glycoprotein, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91f606abaccf8c4d292176abb996313
https://doi.org/10.1128/jvi.00304-19

المؤلفون: Nathalie Brassard, Jonathan Richard, Tristan J. Markle, Andrés Finzi, Mark A. Brockman, Nirmin Alsahafi, Daniel Kaufmann, Bruce D. Walker, Shilei Ding, George K. Lewis

المصدر: Journal of Virology. 90:2993-3002

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, 0301 basic medicine, viruses, Immunology, chemical and pharmacologic phenomena, HIV Infections, Viremia, HIV Antibodies, Microbiology, Epitope, HIV Long-Term Survivors, 03 medical and health sciences, Immune system, Downregulation and upregulation, Virology, medicine, Humans, nef Gene Products, Human Immunodeficiency Virus, chemistry.chemical_classification, Antibody-dependent cell-mediated cytotoxicity, biology, Antibody-Dependent Cell Cytotoxicity, env Gene Products, Human Immunodeficiency Virus, virus diseases, medicine.disease, 3. Good health, 030104 developmental biology, chemistry, Viral replication, Insect Science, HIV-1, biology.protein, Pathogenesis and Immunity, Antibody, Glycoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e595c748c9e609c9efe3b9f0e959ae0b
https://doi.org/10.1128/jvi.02973-15

المؤلفون: Alon Herschhorn, Arne Schön, Jonathan Richard, Andrés Finzi, Luis R. Castillo-Menendez, Myriam Maude Verly, Bruno Melillo, Jérémie Prévost, Amos B. Smith, Joseph Sodroski, Ernesto Freire, Halima Medjahed, Sai Priya Anand, Nirmin Alsahafi

المصدر: Journal of Virology. 92

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, viruses, Immunology, HIV Infections, Trimer, HIV Envelope Protein gp120, Biology, Gp41, Microbiology, Virus, 03 medical and health sciences, Virology, Vaccines and Antiviral Agents, Native state, Humans, chemistry.chemical_classification, env Gene Products, Human Immunodeficiency Virus, virus diseases, HIV Envelope Protein gp41, Transmembrane protein, 3. Good health, HEK293 Cells, 030104 developmental biology, chemistry, Insect Science, CD4 Antigens, Mutation, HIV-1, Mutagenesis, Site-Directed, Biophysics, Protein Multimerization, Isoleucine, Leucine, Glycoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a489637b98858d54b2f54f806e931c6
https://doi.org/10.1128/jvi.01080-18

المؤلفون: Maolin, Lu, Xiaochu, Ma, Luis R, Castillo-Menendez, Jason, Gorman, Nirmin, Alsahafi, Utz, Ermel, Daniel S, Terry, Michael, Chambers, Dongjun, Peng, Baoshan, Zhang, Tongqing, Zhou, Nick, Reichard, Kevin, Wang, Jonathan R, Grover, Brennan P, Carman, Matthew R, Gardner, Ivana, Nikić-Spiegel, Akihiro, Sugawara, James, Arthos, Edward A, Lemke, Amos B, Smith, Michael, Farzan, Cameron, Abrams, James B, Munro, Adrian B, McDermott, Andrés, Finzi, Peter D, Kwong, Scott C, Blanchard, Joseph G, Sodroski, Walther, Mothes

المصدر: Nature. 568(7752)

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Protein Stability, env Gene Products, Human Immunodeficiency Virus, Antibodies, Neutralizing, Single Molecule Imaging, HEK293 Cells, Mutation, Fluorescence Resonance Energy Transfer, HIV-1, Animals, Humans, Cattle, Disulfides, Protein Multimerization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c0558bc7273038407774ef7a980f8fab
https://pubmed.ncbi.nlm.nih.gov/31194935

المؤلفون: Marzena Pazgier, Verna Van, Andrés Finzi, William D. Tolbert, Neelakshi Gohain, Shilei Ding, Nirmin Alsahafi, Loïc Martin, Krishanu Ray, George K. Lewis, Chiara Orlandi

المساهمون: Department of Biomolecular Sciences, University of Urbino 'Carlo Bo', Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Università degli Studi di Urbino 'Carlo Bo'

المصدر: Structure
Structure, Elsevier (Cell Press), 2017, 25 (11), pp.1719-1731.e4. ⟨10.1016/j.str.2017.09.009⟩
Structure, 2017, 25 (11), pp.1719-1731.e4. ⟨10.1016/j.str.2017.09.009⟩

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, T-Lymphocytes, Peptide, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, HIV Antibodies, HIV Envelope Protein gp120, Antibodies, Viral, Crystallography, X-Ray, Epitope, Epitopes, Structural Biology, ComputingMilieux_MISCELLANEOUS, chemistry.chemical_classification, Antibody-dependent cell-mediated cytotoxicity, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, Immunogenicity, virus diseases, Antibodies, Monoclonal, 3. Good health, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], CD4 Antigens, [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology, Antibody, Protein Binding, 030106 microbiology, Article, Cell Line, 03 medical and health sciences, Immune system, [CHIM.CRIS]Chemical Sciences/Cristallography, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM], Molecular Biology, Binding Sites, Sequence Homology, Amino Acid, C-terminus, Molecular Mimicry, Vaccine trial, Antibody-Dependent Cell Cytotoxicity, [SDV.IMM.IMM]Life Sciences [q-bio]/Immunology/Immunotherapy, Virus Internalization, Virology, Molecular biology, Immunity, Innate, 030104 developmental biology, chemistry, biology.protein, HIV-1, Protein Conformation, beta-Strand, Peptides, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245158f359d7b03ff546e8a83c6f96a8
https://hal.archives-ouvertes.fr/hal-02531052

المؤلفون: Jérémie Prévost, Nirmin Alsahafi, Matthew S. Parsons, Mathieu Coutu, Nathalie Brassard, Daniel Kaufmann, Mark A. Brockman, Andrés Finzi, Jonathan Richard

المصدر: Journal of Virology. 91

مصطلحات موضوعية: 0301 basic medicine, 030106 microbiology, Immunology, HIV Infections, chemical and pharmacologic phenomena, Biology, Microbiology, Epitope, HIV Long-Term Survivors, 03 medical and health sciences, Downregulation and upregulation, Virology, Humans, nef Gene Products, Human Immunodeficiency Virus, Antibody-dependent cell-mediated cytotoxicity, Antibody-Dependent Cell Cytotoxicity, virus diseases, hemic and immune systems, Ligand (biochemistry), NKG2D, Blockade, Cell biology, 030104 developmental biology, NK Cell Lectin-Like Receptor Subfamily K, Insect Science, Host-Pathogen Interactions, HIV-1, Pathogenesis and Immunity, Elite controllers, Viral load

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf2e3cc401b8ba61e793b4efb04fcd7d
https://doi.org/10.1128/jvi.00109-17

المؤلفون: Bruno Melillo, Jérémie Prévost, Alon Herschhorn, Olfa Debbeche, Jean-Philippe Chapleau, Navid Madani, Amy M. Princiotto, Amos B. Smith, Nirmin Alsahafi, Joseph Sodroski, Youdong Mao, Beatriz Pacheco, Xin Zeng, Andrés Finzi, Shilei Ding, Christopher Gu

المصدر: Journal of Virology. 91

مصطلحات موضوعية: 0301 basic medicine, Immunogen, Anti-HIV Agents, viruses, Amino Acid Motifs, Immunology, Trimer, HIV Envelope Protein gp120, Biology, Gp41, Microbiology, Piperazines, 03 medical and health sciences, Dogs, Virology, Animals, Humans, Coiled coil, chemistry.chemical_classification, virus diseases, HIV Envelope Protein gp41, Transmembrane protein, Heptad repeat, HEK293 Cells, 030104 developmental biology, chemistry, Ectodomain, Insect Science, HIV-1, Biophysics, Pathogenesis and Immunity, sense organs, Glycoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae089a5b6511072e40d813d1284137f
https://doi.org/10.1128/jvi.02219-16

المؤلفون: Shilei Ding, James B. Munro, Joseph Sodroski, Marzena Pazgier, Jonathan Richard, Amos B. Smith, Mohsen Kazemi, Gloria G. Delgado, Sudipta Bhattacharyya, Bruno Melillo, Jérémie Prévost, Hong Lu, Xueling Wu, Nirmin Alsahafi, William D. Tolbert, Daniel Kaufmann, Sai Priya Anand, Sharon Kirk, Nordine Bakouche, Gabrielle Gendron-Lepage, Walther Mothes, Durba Das, Isabelle Rouiller, Halima Medjahed, Andrés Finzi

المصدر: Cell Host & Microbe. 25:578-587.e5

مصطلحات موضوعية: Antibody-dependent cell-mediated cytotoxicity, chemistry.chemical_classification, 0303 health sciences, biology, CD4 antigen, viruses, virus diseases, Plasma protein binding, Microbiology, Epitope, Neutralization, 3. Good health, Cell biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Protein structure, chemistry, Virology, biology.protein, Parasitology, Antibody, Glycoprotein, 030217 neurology & neurosurgery, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e6625fab990b2cc4364ab1d11057aff0
https://doi.org/10.1016/j.chom.2019.03.002

المؤلفون: Olfa Debbeche, Joseph Sodroski, Nirmin Alsahafi, Andrés Finzi

المصدر: PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0122111 (2015)

مصطلحات موضوعية: viruses, lcsh:Medicine, Plasma protein binding, Biology, HIV Envelope Protein gp120, Gp41, Virus, Epitope, Viral entry, Humans, Disulfides, lcsh:Science, Neutralizing antibody, Multidisciplinary, lcsh:R, virus diseases, Correction, Virus Internalization, Virology, Molecular biology, Antibodies, Neutralizing, Transmembrane protein, HIV Envelope Protein gp41, 3. Good health, Protein Structure, Tertiary, HEK293 Cells, Ectodomain, CD4 Antigens, biology.protein, HIV-1, Mutagenesis, Site-Directed, lcsh:Q, Protein Multimerization, Research Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25c18a7edfe05c8939425ee6adeea35
http://europepmc.org/articles/PMC4444099