المؤلفون: Niels Böhnke, Markus Berger, Nils Griebenow, Antje Rottmann, Michael Erkelenz, Stefanie Hammer, Sandra Berndt, Judith Günther, Antje M. Wengner, Beatrix Stelte-Ludwig, Christoph Mahlert, Simone Greven, Lisa Dietz, Hannah Jörißen, Naomi Barak, Ulf Bömer, Roman C. Hillig, Uwe Eberspaecher, Jörg Weiske, Anja Giese, Dominik Mumberg, Carl Friedrich Nising, Hilmar Weinmann, Anette Sommer

المصدر: Bioconjugate chemistry. 33(6)

مصطلحات موضوعية: Pharmacology, B7 Antigens, Immunoconjugates, Organic Chemistry, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Antineoplastic Agents, Xenograft Model Antitumor Assays, Mice, Structure-Activity Relationship, Cell Line, Tumor, Neoplasms, Animals, Humans, Nicotinamide Phosphoribosyltransferase, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382f52dbd2ea6891f52b4f7a2d6e442b
https://pubmed.ncbi.nlm.nih.gov/35658441

المؤلفون: Joerg Hueser, Peter Sandner, Hanna Tinel, Frank Wunder, Armin Kern, Sherif El Sheikh, Thomas Mondritzki, Frank Eitner, Eva-Maria Becker-Pelster, Martina Schaefer, Joachim Mittendorf, Hubert Truebel, Focco van den Akker, Dieter Lang, Volker Geiss, Tibor Schomber, Andreas Knorr, Vijay Kumar, Karl-Heinz Schlemmer, Lisa Dietz, Agnès Bénardeau, Michael Gerisch, Johannes-Peter Stasch, Nils Griebenow, Michael G. Hahn, Thomas Lampe, Elisabeth Woltering

المصدر: Journal of medicinal chemistry 64(9), 5323-5344 (2021). doi:10.1021/acs.jmedchem.0c02154

مصطلحات موضوعية: inorganic chemicals, Enzyme Activators, Guanosine, Molecular Dynamics Simulation, Pharmacology, Crystallography, X-Ray, medicine.disease_cause, 01 natural sciences, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Soluble Guanylyl Cyclase, Cinaciguat, Heart Rate, Rats, Inbred SHR, Drug Discovery, medicine, Animals, Cytochrome P-450 CYP3A, Structure–activity relationship, heterocyclic compounds, Mode of action, Tissue homeostasis, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, Activator (genetics), Hemodynamics, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Enzyme, Solubility, chemistry, Drug Design, Hypertension, cardiovascular system, Molecular Medicine, Oxidative stress, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1475bcebe92483f464270393a7d6fa32
https://publications.rwth-aachen.de/record/851676

المؤلفون: Sven Wittrock, Carsten Terjung, Anne-Sophie Rebstock, Nils Griebenow, Anette Sommer, Beatrix Stelte-Ludwig, Hans-Georg Lerchen, Yolanda Cancho-Grande, Christoph Mahlert, Sarah Johannes, Sandra Berndt, Simone Greven

المصدر: Angewandte Chemie International Edition. 57:15243-15247

مصطلحات موضوعية: 0301 basic medicine, Drug, Immunoconjugates, media_common.quotation_subject, Kinesins, Antineoplastic Agents, Computational biology, Catalysis, 03 medical and health sciences, In vivo, Cell Line, Tumor, Neoplasms, Drug Discovery, Humans, Pyrroles, Mode of action, media_common, Bioconjugation, Drug discovery, Payload, Chemistry, technology, industry, and agriculture, General Chemistry, body regions, 030104 developmental biology, Kinesin, Linker

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1540c754f2b5da57e05a920741a4d1
https://doi.org/10.1002/anie.201807619

المؤلفون: Volkhart Mj Li, Eva-Maria Becker-Pelster, Jens Ackerstaff, Michael Gerisch, Klemens Lustig, Armin Kern, Hubert Trübel, Peter Dr Fey, Andreas Knorr, Peter Sandner, Nils Griebenow, Axel Kretschmer, Gorden Redlich, Hanna Tinel, Frank Wunder, Karl-Heinz Schlemmer, Johannes-Peter Stasch, Hartmut Schirok, Rolf Jautelat, Volker Geiss, Thomas Mondritzki, Walter Kroh, Markus Follmann, Alexander Straub, Dieter Lang, Joachim Mittendorf

المصدر: Journal of Medicinal Chemistry. 60:5146-5161

مصطلحات موضوعية: Male, 0301 basic medicine, Administration, Oral, Blood Pressure, Chemistry Techniques, Synthetic, 030204 cardiovascular system & hematology, Pharmacology, Heterocyclic Compounds, 2-Ring, Riociguat, Structure-Activity Relationship, 03 medical and health sciences, Dogs, Soluble Guanylyl Cyclase, 0302 clinical medicine, Drug Discovery, medicine, Animals, Humans, Rats, Wistar, Heart Failure, Oxidative metabolism, Chemistry, Treatment options, medicine.disease, Soluble Guanylate Cyclase Stimulator, Pulmonary hypertension, NG-Nitroarginine Methyl Ester, Pyrimidines, 030104 developmental biology, Heart failure, Hepatocytes, Molecular Medicine, Administration, Intravenous, Vericiguat, Rats, Transgenic, Once daily, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaf62afe14d8764ee24c0ab7c8bc7288
https://doi.org/10.1021/acs.jmedchem.7b00449

المؤلفون: Alicia M. Dilmaç, Stefan Bräse, Simone Greven, Nils Griebenow

المصدر: Bioconjugate Chemistry. 27:911-917

مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, 010405 organic chemistry, Stereochemistry, Proton Magnetic Resonance Spectroscopy, Organic Chemistry, Biomedical Engineering, Disulfide bond, Proteins, Pharmaceutical Science, Bioengineering, Peptide, 010402 general chemistry, 01 natural sciences, Mass Spectrometry, Coupling reaction, 0104 chemical sciences, chemistry, Thiol, Proton NMR, Disulfides, Sulfhydryl Compounds, Peptides, Biotechnology, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8995009dd262b73c6173544d25ed7ff
https://doi.org/10.1021/acs.bioconjchem.5b00682

المؤلفون: Christoph Mahlert, Beatrix Stelte-Ludwig, Maria Quanz, Antje Margret Wengner, Sandra Berndt, Markus Berger, Stefanie Hammer, Xiuli Wu, Dominik Mumberg, Zhengzheng Bao, Bertolt Kreft, Lisa Dietz, Hilmar Weinmann, Hannah Joerissen, Andreas Steffen, Anja Giese, Lars Linden, Simone Greven, Niels Boehnke, Anette Sommer, Nils Griebenow

المصدر: Cancer Research. 80:1807-1807

مصطلحات موضوعية: Cancer Research, chemistry.chemical_compound, HaCaT, Oncology, chemistry, Nicotinamide, Cell growth, In vivo, Cell culture, Cancer research, NAD+ kinase, Nicotinamide adenine dinucleotide, In vitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b15fdf3c698600cf6fb773e2e70b786b
https://doi.org/10.1158/1538-7445.am2020-1807

المؤلفون: Judith Günther, Lars Linden, Nils Griebenow, Christoph Mahlert, Antje Rottmann, Markus Berger, Hilmar Weinmann, Anette Sommer, Stefanie Hammer, Carl Friedrich Nising, Niels Böhnke, Bertolt Kreft, Antje Margret Wengner, Dominik Mumber, Anja Giese, Michael Erkelenz, Simone Greven, Beatrix Stelte-Ludwig, Rudolf Beier, Ulf Bömer, Naomi Barak, Hannah Joerissen, Lisa Dietz, Sandra Berndt

المصدر: Cancer Research. 80:2907-2907

مصطلحات موضوعية: Cancer Research, Identification (information), Class (computer programming), Oncology, Computer science, Payload (computing), Cancer therapy, Computational biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d351ca43fee2e2807dad82c27f5a3f5e
https://doi.org/10.1158/1538-7445.am2020-2907

المؤلفون: Sven Wittrock, Hans-Georg Lerchen, Nils Griebenow, Carl-Friedrich Nising

المصدر: Optimizing Antibody-Drug Conjugates for Targeted Delivery of Therapeutics. :56-73

مصطلحات موضوعية: Chemistry, Conjugated system, Combinatorial chemistry, Stoichiometry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6622eb7bd8a575d5293d93421991f68c
https://doi.org/10.4155/fseb2013.13.65

المؤلفون: Nils Griebenow, Hartmut Schirok, Chantal Fürstner, Alicia M. Dilmac

المصدر: Tetrahedron. 71:5597-5601

مصطلحات موضوعية: chemistry.chemical_compound, Trifluoromethyl, chemistry, Block (telecommunications), Organic Chemistry, Drug Discovery, Pyrazolopyridine, Pyridine, Biochemistry, Microwave assisted, Medicinal chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3e444a1c3ab216697420686a9e69a3f9
https://doi.org/10.1016/j.tet.2015.06.050

المؤلفون: Alicia M. Dilmaç, Mario Lobell, Simone Greven, Stefan Bräse, Nils Griebenow

المصدر: RSC Advances. 5:103506-103511

مصطلحات موضوعية: chemistry.chemical_classification, Tetrafluoroborate, General Chemical Engineering, Salt (chemistry), General Chemistry, Combinatorial chemistry, chemistry.chemical_compound, chemistry, Trastuzumab, Hexafluorophosphate, medicine, Organic chemistry, Tyrosine, Selectivity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7fe42ab662e5ce29ac6c8000518e7e07
https://doi.org/10.1039/c5ra18271a

المؤلفون: Alicia M. Dilmaç, Nils Griebenow, Florimond Cumine

المصدر: Synlett. 26:1702-1704

مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Chemistry, Biological profile, Stereochemistry, Allene, Organic Chemistry, Moiety, 2,3-Wittig rearrangement, Amino acid, Stereocenter

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::14af924348e5d975341460148dfb6b79
https://doi.org/10.1055/s-0034-1380740

المؤلفون: Markus Follmann, Franz-Josef Mais, Alexander Straub, Ingo Hartung, Martina Schäfer, Nils Griebenow, Michael G. Hahn, Joachim Mittendorf, Johannes-Peter Stasch, Hartmut Schirok, Friederike Stoll

المصدر: Angewandte Chemie. 125:9618-9639

مصطلحات موضوعية: Chemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8f1267165de32137eba8d994c8f27188
https://doi.org/10.1002/ange.201302588

المؤلفون: Nils Griebenow, Alica M. Dilmac, Stefan Bräse

المصدر: RSC Advances. 5:54301-54303

مصطلحات موضوعية: Reaction conditions, chemistry.chemical_compound, Chemistry, General Chemical Engineering, Batch reactor, Click chemistry, Disulfide bond, General Chemistry, Photochemistry, Derivative (chemistry), Thiol-yne reaction, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b7f379db3c7c278eb3e47a24011fc0a6
https://doi.org/10.1039/c5ra08787b

المؤلفون: Hilmar Bischoff, Jens Schamberger, Peter Kolkhof, Nils Griebenow, Anja Buchmueller

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:3648-3653

مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, Structure-Activity Relationship, Squalene, chemistry.chemical_compound, Biosynthesis, Drug Discovery, medicine, Enzyme Inhibitors, skin and connective tissue diseases, Oxazoles, Molecular Biology, chemistry.chemical_classification, Binding Sites, Molecular Structure, ATP synthase, biology, Chemistry, fungi, Organic Chemistry, In vitro, Enzyme Activation, body regions, Farnesyl-Diphosphate Farnesyltransferase, Enzyme, Enzyme inhibitor, Drug Design, biology.protein, Molecular Medicine, Lapaquistat, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703c648ed73d2200aa116662bd6c634e
https://doi.org/10.1016/j.bmcl.2011.04.092

المؤلفون: Nils Griebenow

المصدر: Amino Acids, Peptides and Proteins in Organic Chemistry: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis, Volume 4

مصطلحات موضوعية: chemistry.chemical_classification, Icofungipen, Alicyclic compound, chemistry, medicine, Organic chemistry, Cispentacin, Tilidine, Amino acid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1e4284f6c78e611488cc47a561ef22ac
https://doi.org/10.1002/9783527631827.ch5

المؤلفون: Anette Sommer, Carsten Terjung, Yolanda Cancho-Grande, Beatrix Stelte-Ludwig, Anne-Sophie Rebstock, Sven Wittrock, Christoph Mahlert, Hans-Georg Lerchen, Sarah Johannes, Simone Greven, Nils Griebenow, Sandra Berndt

المصدر: Angewandte Chemie International Edition. 57:14950-14950

مصطلحات موضوعية: Drug, chemistry.chemical_compound, Bioconjugation, Chemistry, media_common.quotation_subject, Payload (computing), INT, General Chemistry, Combinatorial chemistry, Catalysis, media_common, Pyrrole, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ea796ec937c2947f8cb17c22bb66e2c8
https://doi.org/10.1002/anie.201810987

المؤلفون: Nils Griebenow, Sarah Johannes, Anne-Sophie Rebstock, Carsten Terjung, Anette Sommer, Beatrix Stelte-Ludwig, Simone Greven, Christoph Mahlert, Yolanda Cancho-Grande, Hans-Georg Lerchen, Sven Wittrock, Sandra Berndt

المصدر: Angewandte Chemie. 130:15166-15166

مصطلحات موضوعية: General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6da34b412945ffb7343d23f431d8000e
https://doi.org/10.1002/ange.201810987

المؤلفون: Thorsten Meyer, Nils Griebenow

المصدر: Synlett. 2010:2639-2643

مصطلحات موضوعية: chemistry.chemical_compound, Quinoxaline, Solid-phase synthesis, chemistry, Acetylene, Organic Chemistry, Imidazole, Organic chemistry, Combinatorial synthesis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bc489cd51cdcfdfe11893c6f038aee42
https://doi.org/10.1055/s-0030-1258570

المؤلفون: Hartmut Schirok, Fuerstner Chantal, Alicia M. Dilmac, Nils Griebenow

المصدر: ChemInform. 46

مصطلحات موضوعية: chemistry.chemical_compound, Trifluoromethyl, Chemistry, Block (telecommunications), Pyridine, Organic chemistry, General Medicine, Microwave assisted

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c4d4b4884af4811f97f386981ade7c8e
https://doi.org/10.1002/chin.201549165

المؤلفون: Roger A. Smith, Nils Griebenow

المصدر: High-Throughput Screening in Drug Discovery

مصطلحات موضوعية: Library design, Computer science, Drug discovery, High-throughput screening, Compound management, Combinatorial chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bdb59ea805653f21e396a69c253cb078
https://doi.org/10.1002/9783527609321.ch9