المؤلفون: Xiao-Ping Li (442795), Rajesh K. Harijan (8636538), Bin Cao (186972), Jennifer N. Kahn (8946677), Michael Pierce (56157), Anastasiia M. Tsymbal (11566121), Jacques Y. Roberge (1840720), David Augeri (11566124), Nilgun E. Tumer (226679)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, weight lead compounds, magnitude higher efficiency, four advanced compounds, obtained improved compounds, catalytic site geometry, inhibitors bind remotely, catalytic site, approved inhibitors, structural characterization, ray crystallography, original compound, new strategy, mammalian cells, inhibitory activity, guided approach, first agents, eukaryotic ribosomes, distinctive manner, based methods, acting directly

Relation: https://figshare.com/articles/journal_contribution/Synthesis_and_Structural_Characterization_of_Ricin_Inhibitors_Targeting_Ribosome_Binding_Using_Fragment-Based_Methods_and_Structure-Based_Design/16815050

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01370.s001

المؤلفون: Xiao-Ping Li (442795), Rajesh K. Harijan (8636538), Bin Cao (186972), Jennifer N. Kahn (8946677), Michael Pierce (56157), Anastasiia M. Tsymbal (11566121), Jacques Y. Roberge (1840720), David Augeri (11566124), Nilgun E. Tumer (226679)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, weight lead compounds, magnitude higher efficiency, four advanced compounds, obtained improved compounds, catalytic site geometry, inhibitors bind remotely, catalytic site, approved inhibitors, structural characterization, ray crystallography, original compound, new strategy, mammalian cells, inhibitory activity, guided approach, first agents, eukaryotic ribosomes, distinctive manner, based methods, acting directly

Relation: https://figshare.com/articles/dataset/Synthesis_and_Structural_Characterization_of_Ricin_Inhibitors_Targeting_Ribosome_Binding_Using_Fragment-Based_Methods_and_Structure-Based_Design/16815053

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01370.s002

المؤلفون: Xiao-Ping Li (442795), Rajesh K. Harijan (8636538), Bin Cao (186972), Jennifer N. Kahn (8946677), Michael Pierce (56157), Anastasiia M. Tsymbal (11566121), Jacques Y. Roberge (1840720), David Augeri (11566124), Nilgun E. Tumer (226679)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, weight lead compounds, magnitude higher efficiency, four advanced compounds, obtained improved compounds, catalytic site geometry, inhibitors bind remotely, catalytic site, approved inhibitors, structural characterization, ray crystallography, original compound, new strategy, mammalian cells, inhibitory activity, guided approach, first agents, eukaryotic ribosomes, distinctive manner, based methods, acting directly

Relation: https://figshare.com/articles/dataset/Synthesis_and_Structural_Characterization_of_Ricin_Inhibitors_Targeting_Ribosome_Binding_Using_Fragment-Based_Methods_and_Structure-Based_Design/16815056

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01370.s003

المؤلفون: Xiao-Ping Li (442795), Rajesh K. Harijan (8636538), Bin Cao (186972), Jennifer N. Kahn (8946677), Michael Pierce (56157), Anastasiia M. Tsymbal (11566121), Jacques Y. Roberge (1840720), David Augeri (11566124), Nilgun E. Tumer (226679)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, weight lead compounds, magnitude higher efficiency, four advanced compounds, obtained improved compounds, catalytic site geometry, inhibitors bind remotely, catalytic site, approved inhibitors, structural characterization, ray crystallography, original compound, new strategy, mammalian cells, inhibitory activity, guided approach, first agents, eukaryotic ribosomes, distinctive manner, based methods, acting directly

Relation: https://figshare.com/articles/dataset/Synthesis_and_Structural_Characterization_of_Ricin_Inhibitors_Targeting_Ribosome_Binding_Using_Fragment-Based_Methods_and_Structure-Based_Design/16815059

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01370.s004

المؤلفون: Xiao-Ping Li (442795), Rajesh K. Harijan (8636538), Bin Cao (186972), Jennifer N. Kahn (8946677), Michael Pierce (56157), Anastasiia M. Tsymbal (11566121), Jacques Y. Roberge (1840720), David Augeri (11566124), Nilgun E. Tumer (226679)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, weight lead compounds, magnitude higher efficiency, four advanced compounds, obtained improved compounds, catalytic site geometry, inhibitors bind remotely, catalytic site, approved inhibitors, structural characterization, ray crystallography, original compound, new strategy, mammalian cells, inhibitory activity, guided approach, first agents, eukaryotic ribosomes, distinctive manner, based methods, acting directly

Relation: https://figshare.com/articles/dataset/Synthesis_and_Structural_Characterization_of_Ricin_Inhibitors_Targeting_Ribosome_Binding_Using_Fragment-Based_Methods_and_Structure-Based_Design/16815065

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01370.s006

المؤلفون: Xiao-Ping Li (442795), Rajesh K. Harijan (8636538), Bin Cao (186972), Jennifer N. Kahn (8946677), Michael Pierce (56157), Anastasiia M. Tsymbal (11566121), Jacques Y. Roberge (1840720), David Augeri (11566124), Nilgun E. Tumer (226679)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Chemical Sciences not elsewhere classified, weight lead compounds, magnitude higher efficiency, four advanced compounds, obtained improved compounds, catalytic site geometry, inhibitors bind remotely, catalytic site, approved inhibitors, structural characterization, ray crystallography, original compound, new strategy, mammalian cells, inhibitory activity, guided approach, first agents, eukaryotic ribosomes, distinctive manner, based methods, acting directly

Relation: https://figshare.com/articles/dataset/Synthesis_and_Structural_Characterization_of_Ricin_Inhibitors_Targeting_Ribosome_Binding_Using_Fragment-Based_Methods_and_Structure-Based_Design/16815062

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01370.s005