المؤلفون: Jansson, Anna, 1979, Więckowska, Anna, Björkelid, Christofer, Yahiaoui, Samir, Sooriyaarachchi, Sanjeewani, Lindh, Martin, Bergfors, Terese, Dharavath, Shyamraj, Desroses, Matthieu, Suresh, Surisetti, Andaloussi, Mounir, Nikhil, Rautela, Sreevalli, Sharma, Srinivasa, Bachally R., Larhed, Mats, Jones, T. Alwyn, Karlén, Anders, Mowbray, Sherry L.

المصدر: Journal of Medicinal Chemistry. 56(15):6190-6199

مصطلحات موضوعية: Mycobacterium tuberculosis, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, DXR, Biologi med inriktning mot strukturbiologi, Biology with specialization in Structural Biology, Medicinal Chemistry, Läkemedelskemi

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-196616
https://uu.diva-portal.org/smash/get/diva2:610506/FULLTEXT02.pdf

المؤلفون: Sapna Morayya, Pavithra Viswanath, Achyut Sinha, Nikhil Rautela

المصدر: Acta parasitologica. 61(4)

مصطلحات موضوعية: 0301 basic medicine, Drug, media_common.quotation_subject, Plasmodium falciparum, Drug Evaluation, Preclinical, Diamines, Parasite load, 03 medical and health sciences, chemistry.chemical_compound, Antimalarials, Inhibitory Concentration 50, medicine, Benzothiazoles, Artemisinin, Organic Chemicals, Mode of action, IC50, media_common, biology, Dose-Response Relationship, Drug, Drug discovery, Optical Imaging, biology.organism_classification, 030104 developmental biology, Biochemistry, chemistry, SYBR Green I, Quinolines, Parasitology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7360835fb8fac9b673f9564314d90450
https://pubmed.ncbi.nlm.nih.gov/27787213

المؤلفون: Shridhar Narayanan, Laura M. Sanz, Sreenivasaiah Menasinakai, Kevin Hickling, Abhishek Srivastava, Sapna Morayya, Anandkumar Raichurkar, Vikas Patil, Stefan Kavanagh, María Belén Jiménez-Díaz, Ramanatha Saralaya, Vijender Panduga, Gajanan Shanbag, Eknath V. Bellale, Lyn Rosenbrier-Ribeiro, K.R. Prabhakar, Anisha Ambady, David Waterson, Nikhil Rautela, Kannan Murugan, Pavithra Viswanath, Peter Warner, Pamela Magistrado, Pravin Iyer, Dyann F. Wirth, Jayashree Puttur, Krishna Koushik, Sowmya Bharath, Nilanjana Roy Choudhury, Philipp P. Henrich, Olivia Coburn-Flynn, Suresh Solapure, Radha Nandishaiah, Balachandra Bandodkar, Kakoli Mukherjee, María Santos Martínez, Suresh Rudrapatna, David A. Fidock, Shahul Hameed P, Vinayak Hosagrahara, Monalisa Chatterji, Vasan K. Sambandamurthy, V. Balasubramanian, Sudhir Landge, Jitendar Reddy, Robert E. McLaughlin, Amanda K. Lukens, Adam Jeston Dudley, Disha Awasthy

المصدر: Nature Communications

مصطلحات موضوعية: Phenotypic screening, Guinea Pigs, Plasmodium falciparum, Drug Evaluation, Preclinical, General Physics and Astronomy, Drug resistance, Pharmacology, Article, General Biochemistry, Genetics and Molecular Biology, Antimalarials, In vivo, medicine, Animals, Amines, Multidisciplinary, biology, ATP synthase, Drug Resistance, Microbial, General Chemistry, medicine.disease, biology.organism_classification, Rats, 3. Good health, Pyrimidines, Long acting, Mechanism of action, biology.protein, medicine.symptom, Malaria, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039caecc0852bb3bd72abf0265b59ccf
https://doi.org/10.1038/ncomms7715

المؤلفون: K.R. Prabhakar, Iñigo Angulo-Barturen, Sandra Duffy, Ramachandran Sreekanth A, Shridhar Narayanan, Francisco-Javier Gamo, Laura M. Sanz, Santiago Ferrer, Anandkumar Raichurkar, María Belén Jiménez-Díaz, Vijender Panduga, Sreenivasaiah Menasinakai, Gajanan Shanbhag, Robert Nanduri, Marcus C. S. Lee, Nikhil Rautela, Sapna Morayya, Vinayak Hosagrahara, Disha Awasthy, Olivia Coburn-Flynn, María Santos Martínez, Sowmya Bharath, Jitendar Reddy, Vicky M. Avery, David Waterson, Abhishek Srivastava, Vasan K. Sambandamurthy, Ramanatha Saralaya, Vijayashree Achar, Pravin Iyer, Stefan Kavanagh, David A. Fidock, Shahul Hameed P

المصدر: Journal of medicinal chemistry. 57(15)

مصطلحات موضوعية: Plasmodium berghei, Phenotypic screening, Plasmodium falciparum, Aminopyridines, Mice, SCID, Pharmacology, Antimalarials, Structure-Activity Relationship, Pharmacokinetics, parasitic diseases, Drug Discovery, medicine, Potency, Structure–activity relationship, Animals, Humans, ADME, biology, Chemistry, medicine.disease, biology.organism_classification, Malaria, Rats, Hepatocytes, Microsomes, Liver, Molecular Medicine, Benzimidazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb95443ee2483a372528128662dc1a76
https://pubmed.ncbi.nlm.nih.gov/25007124

المؤلفون: David Waterson, Stefan Kavanagh, V. Balasubramanian, Vijender Panduga, Francisco-Javier Gamo, María Santos Martínez, Shahul Hameed P, Vinayak Hosagrahara, María Belén Jiménez-Díaz, Shubhada Barde, Kakoli Mukherjee, Sandra Duffy, Santiago Ferrer, Vikas Patil, Balachandra Bandodkar, Ramachandran Sreekanth A, K.R. Prabhakar, Suresh Rudrapatna, Praveena Manjrekar, Iñigo Angulo-Barturen, Pravin Iyer, Vasan K. Sambandamurthy, Nikhil Rautela, Pamela Magistrado, Dyann F. Wirth, Sowmya Bharath, Chandan Narayan, Sapna Morayya, Murugan Chinnapattu, Pavithra Viswanath, Anandkumar Raichurkar, Krishna Koushik, Jitender Reddy, Vicky M. Avery, Achyut Sinha, Amanda K. Lukens, Disha Awasthy, Shridhar Narayanan, Laura M. Sanz, Gajanan Shanbag, Sandesh Jatheendranath, Abhishek Srivastava, Ramanatha Saralaya

المصدر: Journal of medicinal chemistry. 57(13)

مصطلحات موضوعية: Cell Survival, Plasmodium falciparum, Biological Availability, Pharmacology, Small Molecule Libraries, Antimalarials, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Pharmacokinetics, Chloroquine, Cell Line, Tumor, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, Antimalarial Agent, Malaria, Falciparum, biology, Chemistry, medicine.disease, biology.organism_classification, Bioavailability, High-Throughput Screening Assays, Mechanism of action, Molecular Medicine, Benzimidazoles, medicine.symptom, Malaria, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4f0771ba5683b3696782fe367bcc4a
https://pubmed.ncbi.nlm.nih.gov/24914738

المؤلفون: R. Kiplin Guy, Santiago Ferrer-Bazaga, Tanya Parkinson, Iñigo Angulo-Barturen, Francisco Javier Gamo-Benito, Michele Connelly, Sandra Duffy, Julie Lotharius, Julie Clark, Balachandra Bandodkar, Nikhil Rautela, Jörg J. Möhrle, Pavithra Viswanath, Timothy N. C. Wells, Sowmya Bharath, Vicky M. Avery

المصدر: Malaria Journal

مصطلحات موضوعية: Male, Drug, Candidate drug re-profiling, medicine.drug_class, Plasmodium berghei, Medicina, media_common.quotation_subject, Plasmodium falciparum, Anti-malarial drugs, Biology, Pharmacology, Antimalarials, Mice, Parasitic Sensitivity Tests, In vitro, In vivo, medicine, Animals, Malaria, Falciparum, Biología y Biomedicina, media_common, Mice, Inbred BALB C, Research, Drug repositioning, in vitro, Protein kinase inhibitor, biology.organism_classification, Malaria, in vivo, Infectious Diseases, Humanized mouse, Parasitology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca663113f92c210767ce7fb50e7460e9
https://hdl.handle.net/10016/37901

المؤلفون: Santiago Ferrer-bazaga, Tanya Parkinson, Pavithra Viswanath, Ra B, Nikhil Rautela, Sowmya Bharath, Ra Duffy, Vicky M Avery, Jörg J Möhrle, R Kiplin Guy, Timothy Wells

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.malariajournal.com/content/pdf/1475-2875-13-143.pdf.

مصطلحات موضوعية: berghei, Candidate drug re-profiling

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.636.5648; http://www.malariajournal.com/content/pdf/1475-2875-13-143.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.636.5648
http://www.malariajournal.com/content/pdf/1475-2875-13-143.pdf

المؤلفون: Jansson, Anna M., Więckowska, Anna, Björkelid, Christofer, Yahiaoui, Samir, Sooriyaarachchi, Sanjeewani, Lindh, Martin, Bergfors, Terese, Dharavath, Shyamraj, Desroses, Matthieu, Suresh, Surisetti, Andaloussi, Mounir, Nikhil, Rautela, Sreevalli, Sharma, Srinivasa, Bachally R., Larhed, Mats, Jones, T. Alwyn, Karlén, Anders, Mowbray, Sherry L.

المصدر: Journal of Medicinal Chemistry; Vol. 56 Issue 15, p6190-6199, 10p