نتائج البحث - "Niessner, Heike"

المصدر: Sinnberg, Tobias; Lichtensteiger, Christa; Hasan Ali, Omar; Pop, Oltin T; Jochum, Ann-Kristin; Risch, Lorenz; Brugger, Silvio D; Velic, Ana; Bomze, David; Kohler, Philipp; Vernazza, Pietro; Albrich, Werner C; Kahlert, Christian R; Abdou, Maire-Therese; Wyss, Nina; Hofmeister, Kathrin; Niessner, Heike; Zinner, Carl; Gilardi, Mara; Tzankov, Alexandar; . (2023). Pulmonary Surfactant Proteins are Inhibited by IgA Autoantibodies in Severe COVID-19. American journal of respiratory and critical care medicine, 207(1), pp. 38-49. American Lung Association 10.1164/rccm.202201-0011OC

مصطلحات موضوعية: 610 Medicine & health

وصف الملف: application/pdf

Relation: https://boris.unibe.ch/171756/

الاتاحة: https://boris.unibe.ch/171756/1/rccm.202201-0011oc.pdf
https://boris.unibe.ch/171756/

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5

Academic Journal

BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS‐mutant melanoma cells: Insights into mode of action and resistance mechanisms

المؤلفون: Dinter, Lisa, Karitzky, Paula C., Schulz, Alexander, Wurm, Alexander A., Mehnert, Marie‐Christin, Sergon, Mildred, Tunger, Antje, Lesche, Mathias, Wehner, Rebekka, Müller, Anja, Käubler, Theresa, Niessner, Heike, Dahl, Andreas, Beissert, Stefan, Schmitz, Marc, Meier, Friedegund, Seliger, Barbara, Westphal, Dana

المساهمون: Bundesministerium für Bildung und Forschung, Deutsche Forschungsgemeinschaft, Deutsche Krebshilfe, EKFS

المصدر: International Journal of Cancer ; volume 154, issue 6, page 1057-1072 ; ISSN 0020-7136 1097-0215

الاتاحة: https://doi.org/10.1002/ijc.34807
https://onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.34807

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6

Academic Journal

Inhibition of p90 ribosomal S6 kinases disrupts melanoma cell growth and immune evasion

المؤلفون: Kosnopfel, Corinna, Wendlinger, Simone, Niessner, Heike, Siewert, Johannes, Sinnberg, Tobias, Hofmann, Angelika, Wohlfarth, Jonas, Schrama, David, Berthold, Marion, Siedel, Claudia, Sauer, Birgit, Jayanthan, Aarthi, Lenz, Georg, Dunn, Sandra E., Schilling, Bastian, Schittek, Birgit

المساهمون: Deutsche Krebshilfe, Medizinischen Fakultät, Eberhard Karls Universität Tübingen, Hiege-Stiftung gegen Hautkrebs, Deutsche Forschungsgemeinschaft, Westfälische Wilhelms-Universität Münster, Universitätsklinikum Münster

المصدر: Journal of Experimental & Clinical Cancer Research ; volume 42, issue 1 ; ISSN 1756-9966

الاتاحة: http://dx.doi.org/10.1186/s13046-023-02755-5
https://link.springer.com/content/pdf/10.1186/s13046-023-02755-5.pdf
https://link.springer.com/article/10.1186/s13046-023-02755-5/fulltext.html

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7

Academic Journal

Features and Long-Term Outcomes of Stage IV Melanoma Patients Achieving Complete Response Under Anti-PD-1-Based Immunotherapy

المؤلفون: Chatziioannou, Eftychia, Leiter, Ulrike, Thomas, Ioannis, Keim, Ulrike, Seeber, Olivia, Meiwes, Andreas, Boessenecker, Isabell, Gonzalez, Stephanie Sanchez, Torres, Francisco Merraz, Niessner, Heike, Sinnberg, Tobias, Forschner, Andrea, Flatz, Lukas, Amaral, Teresa

المساهمون: Universitätsklinikum Tübingen

المصدر: American Journal of Clinical Dermatology ; volume 24, issue 3, page 453-467 ; ISSN 1175-0561 1179-1888

الاتاحة: http://dx.doi.org/10.1007/s40257-023-00775-7
https://link.springer.com/content/pdf/10.1007/s40257-023-00775-7.pdf
https://link.springer.com/article/10.1007/s40257-023-00775-7/fulltext.html

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8

Academic Journal

Deep learning-based scoring of tumour-infiltrating lymphocytes is prognostic in primary melanoma and predictive to PD-1 checkpoint inhibition in melanoma metastases

المصدر: eBioMedicine ; volume 93, page 104644 ; ISSN 2352-3964

الاتاحة: http://dx.doi.org/10.1016/j.ebiom.2023.104644
https://api.elsevier.com/content/article/PII:S2352396423002098?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2352396423002098?httpAccept=text/plain

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9

Academic Journal

Identification of stage I/II melanoma patients at high risk for recurrence using a model combining clinicopathologic factors with gene expression profiling (CP-GEP)

المؤلفون: Amaral, Teresa, Sinnberg, Tobias, Chatziioannou, Eftychia, Niessner, Heike, Leiter, Ulrike, Keim, Ulrike, Forschner, Andrea, Dwarkasing, Jvalini, Tjien-Fooh, Félicia, Wever, Renske, Flatz, Lukas, Eggermont, Alexander, Forchhammer, Stephan

المساهمون: SkylineDx

المصدر: European Journal of Cancer ; volume 182, page 155-162 ; ISSN 0959-8049

الاتاحة: http://dx.doi.org/10.1016/j.ejca.2022.12.021
https://api.elsevier.com/content/article/PII:S0959804922018329?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0959804922018329?httpAccept=text/plain

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10

Academic Journal

Zirkulierende Tumor‐DNA (ctDNA) bei der Entdeckung von Rezidiven bei Melanompatienten mit adjuvanter Anti‐PD‐1‐Therapie

المؤلفون: Forschner, Andrea, Niessner, Heike, Sinnberg, Tobias, Eigentler, Thomas, Amaral, Teresa, Seith, Ferdinand, Garbe, Claus, Biskup, Saskia, Battke, Florian

المصدر: JDDG: Journal der Deutschen Dermatologischen Gesellschaft ; volume 20, issue 6, page 867-871 ; ISSN 1610-0379 1610-0387

الاتاحة: http://dx.doi.org/10.1111/ddg.14766_g
https://onlinelibrary.wiley.com/doi/pdf/10.1111/ddg.14766_g

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11

Academic Journal

Circulating tumor DNA (ctDNA) in the detection of relapse in melanoma patients with adjuvant anti‐PD‐1 therapy

المؤلفون: Forschner, Andrea, Niessner, Heike, Sinnberg, Tobias, Eigentler, Thomas, Amaral, Teresa, Seith, Ferdinand, Garbe, Claus, Biskup, Saskia, Battke, Florian

المصدر: JDDG: Journal der Deutschen Dermatologischen Gesellschaft ; volume 20, issue 6, page 867-871 ; ISSN 1610-0379 1610-0387

الاتاحة: http://dx.doi.org/10.1111/ddg.14766
https://onlinelibrary.wiley.com/doi/pdf/10.1111/ddg.14766

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12

Academic Journal

Augmenting MEK inhibitor efficacy in BRAF wild-type melanoma: synergistic effects of disulfiram combination therapy

المؤلفون: Niessner, Heike, Riel, Simon, Casadei, Nicolas, Kneilling, Manfred, Schaller, Martin, Flatz, Lukas, Macek, Boris, Garbe, Claus, Amaral, Teresa, Sinnberg, Tobias, Meraz Torres, Francisco, Plöger, Sarah, Schörg, Barbara F., Rieß, Olaf

Time: 610

Relation: http://dx.doi.org/10.1186/s13046-023-02941-5; http://hdl.handle.net/10900/157140; http://dx.doi.org/10.15496/publikation-98472

الاتاحة: http://hdl.handle.net/10900/157140
https://doi.org/10.15496/publikation-98472

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13

Academic Journal

BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS-mutant melanoma cells: Insights into mode of action and resistance mechanisms

المؤلفون: Niessner, Heike

Time: 610

Relation: http://dx.doi.org/10.1002/ijc.34807; http://hdl.handle.net/10900/156181; http://dx.doi.org/10.15496/publikation-97513

الاتاحة: http://hdl.handle.net/10900/156181
https://doi.org/10.15496/publikation-97513

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14

Academic Journal

Early disappearance of tumor antigen-reactive T cells from peripheral blood correlates with superior clinical outcomes in melanoma under anti-PD-1 therapy

المساهمون: Klaus Tschira Foundation, Bristol-Myers Squibb, Medical Faculty of the University of Tübingen, Merck Sharp & Dohme

المصدر: Journal for ImmunoTherapy of Cancer ; volume 9, issue 12, page e003439 ; ISSN 2051-1426

الاتاحة: http://dx.doi.org/10.1136/jitc-2021-003439
https://syndication.highwire.org/content/doi/10.1136/jitc-2021-003439

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15

Academic Journal

Case Report: Combined CDK4/6 and MEK Inhibition in Refractory CDKN2A and NRAS Mutant Melanoma

المؤلفون: Forschner, Andrea, Sinnberg, Tobias, Mroz, Gabi, Schroeder, Christopher, Reinert, Christian Philipp, Gatidis, Sergios, Bitzer, Michael, Eigentler, Thomas, Garbe, Claus, Niessner, Heike, Röcken, Martin, Roggia, Cristiana, Armeanu-Ebinger, Sorin, Riess, Olaf, Mattern, Sven, Nann, Dominik, Bonzheim, Irina

المصدر: Frontiers in Oncology ; volume 11 ; ISSN 2234-943X

الاتاحة: http://dx.doi.org/10.3389/fonc.2021.643156
https://www.frontiersin.org/articles/10.3389/fonc.2021.643156/full

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16

Academic Journal

BRAF and MEK inhibitor combinations induce potent molecular and immunological effects in NRAS‐mutant melanoma cells: Insights into mode of action and resistance mechanisms.

المؤلفون: Dinter, Lisa, Karitzky, Paula C., Schulz, Alexander, Wurm, Alexander A., Mehnert, Marie‐Christin, Sergon, Mildred, Tunger, Antje, Lesche, Mathias, Wehner, Rebekka, Müller, Anja, Käubler, Theresa, Niessner, Heike, Dahl, Andreas, Beissert, Stefan, Schmitz, Marc, Meier, Friedegund, Seliger, Barbara, Westphal, Dana

المصدر: International Journal of Cancer; Mar2024, Vol. 154 Issue 6, p1057-1072, 16p

مصطلحات موضوعية: MITOGEN-activated protein kinases, BRAF genes, MELANOMA, PROTEIN kinases, IPILIMUMAB, GENE expression

17

Academic Journal

Tumour progression stage-dependent secretion of YB-1 stimulates melanoma cell migration and invasion

المؤلفون: Kosnopfel, Corinna, Sinnberg, Tobias, Sauer, Birgit, Niessner, Heike, Muenchow, Alina, Fehrenbacher, Birgit, Schaller, Martin, Mertens, Peter R., Garbe, Claus, Thakur, Basant Kumar, Schittek, Birgit

مصطلحات موضوعية: ddc:610

وصف الملف: application/pdf

Relation: https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/21120; urn:nbn:de:bvb:20-opus-211206; https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-211206; https://doi.org/10.3390/cancers12082328; https://opus.bibliothek.uni-wuerzburg.de/files/21120/cancers-12-02328-v2.pdf

الاتاحة: https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/21120
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-211206
https://doi.org/10.3390/cancers12082328
https://opus.bibliothek.uni-wuerzburg.de/files/21120/cancers-12-02328-v2.pdf

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18

Academic Journal

An open-label, single-arm, phase II trial of buparlisib in patients with melanoma brain metastases not eligible for surgery or radiosurgery—the BUMPER study

المؤلفون: Amaral, Teresa, Niessner, Heike, Sinnberg, Tobias, Thomas, Ioannis, Meiwes, Andreas, Garbe, Claus, Garzarolli, Marlene, Rauschenberg, Ricarda, Eigentler, Thomas, Meier, Friedegund

المساهمون: University Hospital Tübingen, Novartis Pharma GmbH

المصدر: Neuro-Oncology Advances ; volume 2, issue 1 ; ISSN 2632-2498

الاتاحة: https://doi.org/10.1093/noajnl/vdaa140
http://academic.oup.com/noa/advance-article-pdf/doi/10.1093/noajnl/vdaa140/33983340/vdaa140.pdf
http://academic.oup.com/noa/article-pdf/2/1/vdaa140/34675342/vdaa140.pdf

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19

Academic Journal

Expression of DNA Methyltransferase 1 Is a Hallmark of Melanoma, Correlating with Proliferation and Response to B-Raf and Mitogen-Activated Protein Kinase Inhibition in Melanocytic Tumors

المؤلفون: Gassenmaier, Maximilian, Rentschler, Maximilian, Fehrenbacher, Birgit, Eigentler, Thomas K., Ikenberg, Kristian, Kosnopfel, Corinna, Sinnberg, Tobias, Niessner, Heike, Bösmüller, Hans, Wagner, Nikolaus B., Schaller, Martin, Garbe, Claus, Röcken, Martin

المساهمون: Novartis Pharma

المصدر: The American Journal of Pathology ; volume 190, issue 10, page 2155-2164 ; ISSN 0002-9440

الاتاحة: http://dx.doi.org/10.1016/j.ajpath.2020.07.002
https://api.elsevier.com/content/article/PII:S0002944020303357?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0002944020303357?httpAccept=text/plain

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20

Academic Journal

Exploring the In Vitro and In Vivo Therapeutic Potential of BRAF and MEK Inhibitor Combination in NRAS-Mutated Melanoma.

المؤلفون: Niessner, Heike^1,2 (AUTHOR) anna_huesch@web.de, Hüsch, Anna¹ (AUTHOR), Kosnopfel, Corinna³ (AUTHOR) corinnaveronica.kosnopfel@ukmuenster.de, Meinhardt, Matthias^4,5 (AUTHOR) dana.westphal@uniklinikum-dresden.de, Westphal, Dana^5,6 (AUTHOR) friedegund.meier@uniklinikum-dresden.de, Meier, Friedegund^5,6,7 (AUTHOR), Schilling, Bastian⁸ (AUTHOR) schilling_b@ukw.de, Sinnberg, Tobias^1,2,9 (AUTHOR) heike.niessner@med.uni-tuebingen.de

المصدر: Cancers. Dec2023, Vol. 15 Issue 23, p5521. 23p.

مصطلحات موضوعية: *THERAPEUTIC use of antineoplastic agents, *DRUG efficacy, *IN vitro studies, *GENETIC mutation, *COMBINATION drug therapy, *IN vivo studies, *XENOGRAFTS, *ONCOGENES, *MELANOMA, *PROTEIN kinase inhibitors, *ANIMAL experimentation, *ENDOPLASMIC reticulum, *INDIVIDUALIZED medicine, *APOPTOSIS, *METASTASIS, *CELL physiology, *CANCER patients, *TRANSFERASES, *CHALONES, *CELL lines, *PATIENT safety, *MICE, *EVALUATION

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