المؤلفون: Carole G. Campion, Kossay Zaoui, Thomas Verissimo, Suzanne Cossette, Hiroyuki Matsuda, Nicolas Solban, Pavel Hamet, Johanne Tremblay

المصدر: Cell Reports, Vol 24, Iss 3, Pp 670-684.e7 (2018)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124718309835; https://doaj.org/toc/2211-1247

URL الوصول: https://doaj.org/article/c9937679ce4c4966842e67bbacc9541a

المؤلفون: Brett Hopkins (11291030), Hongjun Zhang (1350582), Indu Bharathan (2125537), Derun Li (1792951), Qinglin Pu (7456739), Hua Zhou (50017), Theodore A. Martinot (1479601), Xavier Fradera (2585029), Alfred Lammens (411252), Charles A. Lesburg (1834624), Ryan D. Cohen (1458091), Jeanine Ballard (2245573), Ian Knemeyer (1398904), Karin Otte (7456745), Stella Vincent (2369365), J. Richard Miller (1648261), Nicolas Solban (7456751), Mangeng Cheng (411194), Prasanthi Geda (1412485), Nadya Smotrov (8575140), Xuelei Song (1463755), David Jonathan Bennett (7456754), Yongxin Han (1235268)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Pharmacology, Biotechnology, Developmental Biology, Hematology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, Metabolite identification, Low-Dose IDO 1 Inhibitors Herein, dose, Structural Data, cyclopropyl compounds, 9 mg, QD, cyclopropane rings, tetrahydronaphthyridine series, Guide Design, IDO 1 inhibitors, blood potency

Relation: https://figshare.com/articles/journal_contribution/Utilization_of_Metabolite_Identification_and_Structural_Data_to_Guide_Design_of_Low-Dose_IDO1_Inhibitors/15190091

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00265.s001

المؤلفون: Tayyaba Hasan, Nicolas Solban, Imran Rizvi, Sung K. Chang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7705a5186528e6c8c095b97b25734e05
https://doi.org/10.1158/1078-0432.22439799

المؤلفون: Ravindra Kumar, Jasbir Seehra, Kathryn W. Underwood, R. Scott Pearsall, Jeffrey A. Ucran, Nicolas Solban, Travis E. Monnell, Roselyne Castonguay, Asya V. Grinberg, Aaron W. Mulivor, Eileen G. Pobre, Dianne Mitchell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d62b66268345b52b0f0b8aa7db8311c
https://doi.org/10.1158/1535-7163.c.6532256

المؤلفون: Ravindra Kumar, Jasbir Seehra, Kathryn W. Underwood, R. Scott Pearsall, Jeffrey A. Ucran, Nicolas Solban, Travis E. Monnell, Roselyne Castonguay, Asya V. Grinberg, Aaron W. Mulivor, Eileen G. Pobre, Dianne Mitchell

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c5eebbcf9ce0bdb38c2a3af3223ee68
https://doi.org/10.1158/1535-7163.22486142

المؤلفون: Tayyaba Hasan, Nicolas Solban, Imran Rizvi, Sung K. Chang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c38d4b09616cf5115d5a112d36b483f
https://doi.org/10.1158/1078-0432.c.6517215

المؤلفون: Charles P. Lin, Tayyaba Hasan, Xunbin Wei, William L. Rice, John Novak, Nicolas Solban, Irene Georgakoudi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09781a8a8601d92b02792fe81bd71a98
https://doi.org/10.1158/0008-5472.22363218.v1

المؤلفون: Charles P. Lin, Tayyaba Hasan, Xunbin Wei, William L. Rice, John Novak, Nicolas Solban, Irene Georgakoudi

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f57d0a42b93caf113d612c9a5ebb8ce4
https://doi.org/10.1158/0008-5472.c.6493608

المؤلفون: Nicolas Solban, Alexander Pasternak, Qinglin Pu, Amy C. Doty, David Jonathan Bennett, Charles A. Lesburg, Wensheng Yu, Prasanthi Geda, Nunzio Sciammetta, J. Richard Miller, Hua Zhou, Xuelei Song, Yongxin Han, Lars Neumann, David L. Sloman, Mangeng Cheng, Heidi Ferguson, Karin M. Otte, Liangqin Guo, Hongjun Zhang, Alfred Lammens, Xavier Fradera, Meredeth A. McGowan

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Bicyclic molecule, 010405 organic chemistry, Chemistry, Stereochemistry, Organic Chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Pentane, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Amide, Drug Discovery, Moiety, Potency, Bioisostere, Indoleamine 2,3-dioxygenase, Benzamide

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc457a333eeebf89280777405619540
https://doi.org/10.1021/acsmedchemlett.0c00195

المؤلفون: Lu Zhang, Brian Long, Nicolas Solban, Razvan Cristescu, I‑Ming Wang, Gefei Zeng

المصدر: Molecular Medicine Reports

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, B-cell receptor, Immunoglobulin Variable Region, Receptors, Antigen, T-Cell, Receptors, Antigen, B-Cell, Spleen, Biology, Biochemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Mutation Rate, Cell Line, Tumor, Neoplasms, Genetics, medicine, Animals, Tissue Distribution, Framework region, Immune Checkpoint Inhibitors, Molecular Biology, Lymph node, B cell receptor, murine anti-PD-1, T-cell receptor, breakpoint cluster region, Antibodies, Monoclonal, Cancer, Articles, medicine.disease, Complementarity Determining Regions, Mice, Inbred C57BL, Transplantation, Isogeneic, MC38, 030104 developmental biology, medicine.anatomical_structure, Oncology, Immunoglobulin J-Chains, 030220 oncology & carcinogenesis, Cancer research, Molecular Medicine, Immunoglobulin heavy chain, Female, Lymph Nodes, T cell receptor, Immunoglobulin Heavy Chains, clonotype

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69f14361e3b6a3857bc93341c689211
https://doi.org/10.3892/mmr.2020.11169

المؤلفون: Derun Li, David L. Sloman, Abdelghani Achab, Hua Zhou, Meredeth A. McGowan, Catherine White, Craig Gibeau, Hongjun Zhang, Qinglin Pu, Indu Bharathan, Brett Hopkins, Kun Liu, Heidi Ferguson, Xavier Fradera, Charles A. Lesburg, Theodore A. Martinot, Ji Qi, Zhiguo J. Song, Jingjun Yin, Huangguang Zhang, Licheng Song, Baoqiang Wan, Suzanne DAddio, Nicolas Solban, J. Richard Miller, Beata Zamlynny, Alan Bass, Elizabeth Freeland, Bridget Ykoruk, Catherine Hilliard, Jude Ferraro, Jin Zhai, Ian Knemeyer, Karin M. Otte, Stella Vincent, Nunzio Sciammetta, Alexander Pasternak, David Jonathan Bennett, Yongxin Han

المصدر: Journal of medicinal chemistry. 65(8)

مصطلحات موضوعية: Cyclization, Ethers, Cyclic, Drug Discovery, Molecular Medicine, Indoleamine-Pyrrole 2,3,-Dioxygenase, Enzyme Inhibitors, Amides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65de888aa90fb7088ca022d5b5ddf12
https://pubmed.ncbi.nlm.nih.gov/35239336

المؤلفون: Theodore A. Martinot, Xavier Fradera, Meredeth A. McGowan, Wensheng Yu, Heidi Ferguson, Purakattle J Biju, H. Zhou, Nicolas Solban, Qinglin Pu, Yongxin Han, Xiao Wang, Kun Liu, Ravi Kurukulasuriya, Yu-hong Lam, Abdelghani Achab, Karin M. Otte, Michael J. Ardolino, Amy C. Doty, Charles A. Lesburg, J. Richard Miller, Yongqi Deng, Mangeng Cheng, Hongjun Zhang, Ian Knemeyer, Nunzio Sciammetta, David Jonathan Bennett

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Standard of care, Combination therapy, 010405 organic chemistry, Chemistry, Drug candidate, medicine.medical_treatment, Immune checkpoint inhibitors, Organic Chemistry, Computational biology, Metabolic stability, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Overall response rate, Cancer immunotherapy, Drug Discovery, medicine, Indoleamine 2,3-dioxygenase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c30fa3b8f261ace5c7d56e064b7047fa
https://doi.org/10.1021/acsmedchemlett.9b00344

المؤلفون: Derun Li, Hongjun Zhang, Hua Zhou, Xuelei Song, Theodore A. Martinot, Prasanthi Geda, Brett A. Hopkins, Jeanine E. Ballard, Stella H. Vincent, Yongxin Han, Nicolas Solban, Karin M. Otte, Mangeng Cheng, J. Richard Miller, Qinglin Pu, Indu Bharathan, Charles A. Lesburg, Ryan D. Cohen, Ian Knemeyer, David Jonathan Bennett, Xavier Fradera, Alfred Lammens, Nadya Smotrov

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: Oral dose, Chemistry, Metabolite, Organic Chemistry, Low dose, Pharmacology, Metabolic stability, Biochemistry, Chemical synthesis, chemistry.chemical_compound, Pharmacokinetics, Drug Discovery, Potency, Whole blood

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83daf5d6fb5e002887daecc8d7be71ff
https://pubmed.ncbi.nlm.nih.gov/34531952

المؤلفون: Milind D. Chalishazar, Nicolas Solban, Johnny Kopinja, Doug Linn, Razvan Cristescu, Heather Zhou, Thomas Rosahl, Brian Long, Weisheng Zhang, Eric Hostetler

المصدر: Cancer Research. 82:2455-2455

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7cffc9627c7426a05efd87e2e1b445aa
https://doi.org/10.1158/1538-7445.am2022-2455

المؤلفون: Amy Loughlin, Lisa LaFranco-Scheuch, Heather Vu, Tara Grady Styring, Nianyu Li, Stephen Pacchione, Warren E. Glaab, Alan S. Bass, Nicolas Solban, J. Richard Miller, Ivy Garfinkel, Heather Zhou, Bhavana Bhatt, Amy G. Aslamkhan, Qiuwei Xu, Kara Pearson, Spencer Reynolds

المصدر: Toxicology and applied pharmacology. 406

مصطلحات موضوعية: 0301 basic medicine, Male, Serotonin, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Animals, Indoleamine-Pyrrole 2,3,-Dioxygenase, Metabolomics, ortho-Aminobenzoates, Indoleamine 2,3-dioxygenase, Kynurenine, Pharmacology, Mice, Knockout, Nicotinamide, Catabolism, Tryptophan, Wild type, Molecular biology, Tryptophan Oxygenase, 030104 developmental biology, chemistry, Liver, 030220 oncology & carcinogenesis, Knockout mouse, Female, Metabolic Networks and Pathways, Spleen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08c237f8a3695db28c4ce9aee4f1a171
https://pubmed.ncbi.nlm.nih.gov/32871117

المؤلفون: Nicolas Solban, Selbo K. Pål, Sinha K. Alok, Contact The Aacr, Selbo K. Pa˚l, Chang K. Sung, Tayyaba Hasan

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://cancerres.aacrjournals.org/content/66/11/5633.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.322.1306; http://cancerres.aacrjournals.org/content/66/11/5633.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.322.1306
http://cancerres.aacrjournals.org/content/66/11/5633.full.pdf

المؤلفون: Brian Long, Adam Procopio, Sheila Ranganath, Sachin Mittal, Yun Wang, Clayton T. Larsen, Robert Saklatvala, Allen C. Templeton, Heidi Ferguson, Jun Xu, Mingmei Cai, Ernest G. Schutt, Ken Lin, Miller Paul, Rhodemann Li, Samanthi A. Perera, Nicolas Solban

المصدر: Advanced Therapeutics. 4:2170031

مصطلحات موضوعية: Pharmacology, Agonist, business.industry, medicine.drug_class, Biochemistry (medical), Pharmaceutical Science, Medicine (miscellaneous), Immune modulation, Sting, Tumor regression, Cancer research, Medicine, Pharmacology (medical), business, Sonoporation, Genetics (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23eb9134502a5e9e2801109409844426
https://doi.org/10.1002/adtp.202170031

المؤلفون: Sheila Ranganath, Ernest G. Schutt, Jun Xu, Mingmei Cai, Ken Lin, Heidi Ferguson, Nicolas Solban, Adam Procopio, Brian Long, Clayton T. Larsen, Rhodemann Li, Sachin Mittal, Robert Saklatvala, Yun Wang, Allen C. Templeton, Miller Paul, Samanthi A. Perera

المصدر: Advanced Therapeutics. 4:2100154

مصطلحات موضوعية: Pharmacology, Agonist, business.industry, medicine.drug_class, Biochemistry (medical), Pharmaceutical Science, Medicine (miscellaneous), Immune modulation, Sting, Drug delivery, Cancer research, Tumor regression, Medicine, Pharmacology (medical), business, Sonoporation, Genetics (clinical)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::37fa70dd5a9fe332721d6b37ae7bde83
https://doi.org/10.1002/adtp.202100154

المؤلفون: Razvan Cristescu, Brian Long, Douglas Linn, Nicolas Solban, Cai Li

المصدر: Cancer Research. 79:4615-4615

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Hematology, business.industry, Cancer, Inflammation, medicine.disease, Systemic inflammation, Cachexia, Metastasis, Immune system, Oncology, Tumor progression, Internal medicine, Cancer research, Medicine, medicine.symptom, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::889d26e6110e93eb8957edcd30a4d868
https://doi.org/10.1158/1538-7445.am2019-4615

المؤلفون: Jonathan P. Celli, Alvin Liang, Nicolas Solban, Tayyaba Hasan, Stephen P. Pereira

المصدر: Lasers in Surgery and Medicine. 43:565-574

مصطلحات موضوعية: Pathology, medicine.medical_specialty, business.industry, medicine.medical_treatment, Photodynamic therapy, Dermatology, medicine.disease, Verteporfin, eye diseases, Gemcitabine, chemistry.chemical_compound, chemistry, Apoptosis, Cell culture, Pancreatic cancer, medicine, Cancer research, Surgery, Deoxycytidine, Ovarian cancer, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::65f0485e6234de374a69c5370d897f25
https://doi.org/10.1002/lsm.21093