المؤلفون: Arnaud Pillon, Bruno Gomes, Isabelle Vandenberghe, Valérie Cartron, Patrick Cèbe, Jean-Christophe Blanchet, Vincent Sibaud, Nicolas Guilbaud, Laurent Audoly, Laurence Lamant, Anna Kruczynski

المصدر: PLoS ONE, Vol 12, Iss 6, p e0179991 (2017)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5491107?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/9a3be95c1fc441a59b977904332b2515

المؤلفون: Sabrina Pesnel, Arnaud Pillon, Laurent Créancier, Stéphanie Lerondel, Alain Le Pape, Christian Recher, Cécile Demur, Nicolas Guilbaud, Anna Kruczynski

المصدر: PLoS ONE, Vol 7, Iss 1, p e30690 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3267751?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/8c88429517e84eb296d1f31dfea5fdfe

المؤلفون: Marine Chartrain, Joëlle Riond, Aline Stennevin, Isabelle Vandenberghe, Bruno Gomes, Laurence Lamant, Nicolas Meyer, Jean Edouard Gairin, Nicolas Guilbaud, Jean Philippe Annereau

المصدر: PLoS ONE, Vol 7, Iss 5, p e36762 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3360047?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/47c75d2150a74c11a50d82e4a7da4143

المؤلفون: Sonia Chelouah, Caroline Monod-Wissler, Christian Bailly, Jean-Marc Barret, Nicolas Guilbaud, Stéphane Vispé, Emmanuel Käs

المصدر: PLoS ONE, Vol 6, Iss 8, p e23597 (2011)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3154508?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/b1d1912dce004edb85b70ec809d417d7

المؤلفون: Patrick Calsou, Nicolas Guilbaud, Bruno Gomes, Carine Racca, Philippe Frit, Dennis Gomez, Florence Larminat, Oriane Bombarde

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014008e5c625cae9dbcd3afc50deb92e
https://doi.org/10.1158/1535-7163.22508979.v1

المؤلفون: Patrick Calsou, Nicolas Guilbaud, Bruno Gomes, Carine Racca, Philippe Frit, Dennis Gomez, Florence Larminat, Oriane Bombarde

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acd863953ab0031482d892e7d36b0a9
https://doi.org/10.1158/1535-7163.22508985.v1

المؤلفون: Christian Bailly, Jean-Marc Barret, Nicolas Guilbaud, Charles Dumontet, Didier Cussac, Jean-Philippe Annereau, Jesper Q. Svejstrup, David J. Hobson, Sophie Bréand, Jérome Besse, Laurent Créancier, Luc DeVries, Stéphane Vispé

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228be85587ab7332098bd38bdc32658e
https://doi.org/10.1158/1535-7163.c.6531635

المؤلفون: Bruno Gomes, Nicolas Guilbaud, Pierre Ferré, Xavier Thuru, Laurent Nguyen, Thierry Marchal, Stéphane Couffin, Viviane Brel, Aurélie Pétain, Emmanuel Bouchaert, Ingrid Bemelmans, Zacharie Segaoula, François Serres, Dominique Tierny

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de96f28128007b88484bfc316fdf834
https://doi.org/10.1158/1078-0432.22460913.v1

المؤلفون: Christian Bailly, Jean-Marc Barret, Nicolas Guilbaud, Charles Dumontet, Didier Cussac, Jean-Philippe Annereau, Jesper Q. Svejstrup, David J. Hobson, Sophie Bréand, Jérome Besse, Laurent Créancier, Luc DeVries, Stéphane Vispé

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9663a2f107aece705dc218648dcf711d
https://doi.org/10.1158/1535-7163.22484879.v1

المؤلفون: Bruno Gomes, Nicolas Guilbaud, Pierre Ferré, Xavier Thuru, Laurent Nguyen, Thierry Marchal, Stéphane Couffin, Viviane Brel, Aurélie Pétain, Emmanuel Bouchaert, Ingrid Bemelmans, Zacharie Segaoula, François Serres, Dominique Tierny

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7a56b63ce7133a44dd0c33f0c33168
https://doi.org/10.1158/1078-0432.c.6524640.v1

المؤلفون: Toshiyuki Isae, Masabumi Shibuya, Kinya Kubo, Rika Suzuki, Yasunari Fujiwara, Kazuo Kubo, Kazumasa Hasegawa, Nicolas Guilbaud, Francis Bichat, Kazumi Takahashi, Atsushi Yamamoto, Toru Miura, Eri Taguchi, Kazuhide Nakamura

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76e1e571087f5887b568d44c13707f4
https://doi.org/10.1158/0008-5472.22364580.v1

المؤلفون: Christian Bailly, Thierry Imbert, Nicolas Guilbaud, Amélie Lansiaux, Jean-Guy Delcros, Yves Guminski, Viviane Brel, Jean-Philippe Annereau, Stéphane Vispé, Anna Kruczynski, Jean-Marc Barret

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c7427cf4887b47107cce01df03a7440
https://doi.org/10.1158/0008-5472.22377222

المؤلفون: Toshiyuki Isae, Masabumi Shibuya, Kinya Kubo, Rika Suzuki, Yasunari Fujiwara, Kazuo Kubo, Kazumasa Hasegawa, Nicolas Guilbaud, Francis Bichat, Kazumi Takahashi, Atsushi Yamamoto, Toru Miura, Eri Taguchi, Kazuhide Nakamura

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7425b04994428348f885c719ee234b1f
https://doi.org/10.1158/0008-5472.c.6494259.v1

المؤلفون: Marie-Paule Sablin, Christophe Le Tourneau, Nicolas Guilbaud, Carlos Gomez-Roca, Jean-Pierre Delord, Mariya Pavlyuk, Andrea Varga, Aurélie Pétain, Alexandra Leary

المصدر: Investigational New Drugs

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Neutropenia, F14512, Efficacy, Nausea, Platinum Compounds, Gastroenterology, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Ovarian cancer, Phase I Studies, Dose-escalation, Internal medicine, Polyamines, medicine, Humans, Topoisomerase II Inhibitors, Pharmacology (medical), Adverse effect, Aged, Podophyllotoxin, Ovarian Neoplasms, Pharmacology, Polyamine transport, business.industry, Cancer, Middle Aged, medicine.disease, Treatment Outcome, 030104 developmental biology, Oncology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Pharmacodynamics, Female, Safety, medicine.symptom, business, Febrile neutropenia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202e65862d2b7c8e01527b00baefb0f9
https://doi.org/10.1007/s10637-018-0688-4

المؤلفون: Quentin Pascal, Nicolas Guilbaud, Pierre Boyé, François Machuron, Pierre Ferré, François Serres, Laurent Marescaux, Sandy Courapied, Kévyn Geeraert, Aurélie Pétain, Claire Mazuy, Corinne Fournel-Fleury, Juliette Hordeaux, Dominique Tierny, Agata Marta Rybicka, Virginie Coste, Zacharie Segaoula, Bruno Gomes, Alain Duhamel, Emmanuel Bouchaert, Franck Floch

المساهمون: Oncovet, Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 (JPArc), Université Lille Nord de France (COMUE)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille, Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U 1192 (PRISM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Evaluation des technologies de santé et des pratiques médicales - ULR 2694 (METRICS), Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Université Lille Nord (France), Centre de Recherche Pierre Fabre (Centre de R&D Pierre Fabre), PIERRE FABRE, CHU Lille, INSERM, Université de Lille, Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 [JPArc], Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U1192, Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U 1192 [PRISM], METRICS : Evaluation des technologies de santé et des pratiques médicales - ULR 2694, Centre de Recherche Pierre Fabre [Centre de R&D Pierre Fabre]

المصدر: Boyé, P, Floch, F, Serres, F, Segaoula, Z, Hordeaux, J, Pascal, Q, Coste, V, Courapied, S, Bouchaert, E, Rybicka, A, Mazuy, C, Marescaux, L, Geeraert, K, Fournel-Fleury, C, Duhamel, A, Machuron, F, Ferré, P, Pétain, A, Guilbaud, N, Tierny, D & Gomes, B 2020, ' Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma ', Oncotarget, vol. 11, no. 7, pp. 671-686 . https://doi.org/10.18632/oncotarget.27461
Oncotarget
Oncotarget, 2020, Oncotarget, 11, pp.671-686. ⟨10.18632/oncotarget.27461⟩

مصطلحات موضوعية: 0301 basic medicine, F14512, [SDV]Life Sciences [q-bio], Population, Etoposide Phosphate, Subgroup analysis, Pharmacology, P-glycoprotein, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Epipodophyllotoxin, hemic and lymphatic diseases, Medicine, education, Adverse effect, Etoposide, pet dog model, education.field_of_study, business.industry, non-Hodgkin lymphoma, medicine.disease, Lymphoma, Clinical trial, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, etoposide phosphate, business, Research Paper, medicine.drug

وصف الملف: application/pdf; application/octet-stream; application/rdf+xml; charset=utf-8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850744eef564c2e4927bae2bf11c68b1
https://www.pure.ed.ac.uk/ws/files/138529322/27461_1049601_1_PB.pdf

المؤلفون: Romain Baer, Laia Masvidal-Sanz, Sauyeun Shin, Julie Guillermet-Guibert, Manon Strehaiano, Yoshinori Tsukumo, Corinne Bousquet, Nahum Sonenberg, Ola Larsson, Stéphane Pyronnet, Nicolas Guilbaud, Yvan Martineau, Jean-Sébastien Hoffmann, Théo Goullet de Rugy, Frédéric Marion, David Müller, Christine Jean, Rémi Samain

المصدر: JCI Insight. 4

مصطلحات موضوعية: DNA Replication, 0301 basic medicine, DNA damage, DNA repair, Cell Cycle Proteins, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Protein biosynthesis, Animals, Humans, PI3K/AKT/mTOR pathway, Adaptor Proteins, Signal Transducing, Acinar cell proliferation, Messenger RNA, Chemistry, TOR Serine-Threonine Kinases, DNA replication, Translation (biology), General Medicine, Pancreatic Neoplasms, 030104 developmental biology, Protein Biosynthesis, 030220 oncology & carcinogenesis, Eukaryotic Initiation Factor-4A, Cancer research, Research Article, Carcinoma, Pancreatic Ductal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c19ad875afea3b560aa3a9ce792dbf9
https://doi.org/10.1172/jci.insight.121951

المؤلفون: Nicolas Guilbaud, Bruno Gomes, Isabelle Vandenberghe, Anna Kruczynski, Antonio Grondin, Arnaud Pillon

المصدر: Bioanalysis. 8:1481-1498

مصطلحات موضوعية: Drug, Bioanalysis, media_common.quotation_subject, Clinical Biochemistry, Antineoplastic Agents, Pharmacology, 030226 pharmacology & pharmacy, 01 natural sciences, Mass Spectrometry, Analytical Chemistry, Mice, 03 medical and health sciences, 0302 clinical medicine, Qualitative analysis, In vivo, Cell Line, Tumor, Drug Discovery, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Chromatography, High Pressure Liquid, PK/PD models, media_common, Leukemia, Chemistry, Drug discovery, 010401 analytical chemistry, General Medicine, 0104 chemical sciences, Medical Laboratory Technology, Oncology drug, Female, Dried Blood Spot Testing, Sample collection, Drug Monitoring

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cfad1b60aaba9a016a1c63da9964ad0
https://doi.org/10.4155/bio-2016-0062

المؤلفون: Frédéric Marion, Nicolas Guilbaud, Philippe Schmitt, Frédéric Liéby-Muller, Jean-Philippe Annereau, Christian Bailly, Anna Kruczynski

المصدر: Bioorganic & Medicinal Chemistry Letters. 25:184-187

مصطلحات موضوعية: Chemistry, Stereochemistry, Hydrochloride, Organic Chemistry, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Alkaloids, Cryptopleurine, Cell Line, Tumor, Drug Discovery, Humans, Molecular Medicine, Cancer cell lines, Cytotoxicity, Chirality (chemistry), Molecular Biology, Cell Proliferation, Biological evaluation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19f2fca97b60a02e97afa6c64de7d13a
https://doi.org/10.1016/j.bmcl.2014.11.086

المؤلفون: Florence Larminat, Philippe Frit, Dennis Gomez, Oriane Bombarde, Carine Racca, Nicolas Guilbaud, Bruno Gomes, Patrick Calsou

المساهمون: Institut de pharmacologie et de biologie structurale (IPBS), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Biologie Cellulaire et Moléculaire du Contrôle de la Prolifération (LBCMCP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre de Biologie Intégrative (CBI), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Onco-Pharmacologie (LOP), Université de Reims Champagne-Ardenne (URCA)-JE2428, iTeos Therapeutics (iTeos), Centre National de la Recherche Scientifique (CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Centre de Physiopathologie Toulouse Purpan (CPTP), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), JE2428-Université de Reims Champagne-Ardenne (URCA)

المصدر: Molecular Cancer Therapeutics
Molecular Cancer Therapeutics, American Association for Cancer Research, 2017, 16 (10), pp.2166-2177. ⟨10.1158/1535-7163.MCT-16-0767⟩

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, [SDV]Life Sciences [q-bio], Genetic Vectors, RAD51, Apoptosis, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Neoplasms, medicine, Polyamines, Humans, Topoisomerase II Inhibitors, DNA Breaks, Double-Stranded, Etoposide, ComputingMilieux_MISCELLANEOUS, Podophyllotoxin, Polyamine transport, BRCA1 Protein, Topoisomerase, Molecular biology, Chromatin, Cell biology, 030104 developmental biology, Cell killing, DNA Topoisomerases, Type II, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Rad51 Recombinase, DNA, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a2e51c779e08055469b930a9d399b4
https://pubmed.ncbi.nlm.nih.gov/28611105

المؤلفون: Virginie Albinet, Thierry Levade, Carmen Bedia, Nathalie Andrieu-Abadie, Sonia-Caroline Sorli, Bruno Ségui, Christian Touriol, Josefina Casas, Nicolas Guilbaud, Alexandre Dubrac, Gemma Fabriàs, Sandra Colié

المصدر: The FASEB Journal. 27:489-498

مصطلحات موضوعية: Ceramide, Transplantation, Heterologous, Down-Regulation, Mice, Nude, Apoptosis, Ceramides, Glucosylceramides, Biochemistry, Mice, chemistry.chemical_compound, Cell Line, Tumor, Genetics, medicine, Animals, Humans, Melanoma, Molecular Biology, Cell Proliferation, Sphingolipids, Cell growth, beta-Glucosidase, Endoplasmic reticulum, Endoplasmic Reticulum Stress, medicine.disease, Sphingolipid, Cell biology, chemistry, Tumor progression, Unfolded Protein Response, Unfolded protein response, Glucosylceramidase, Female, Mutant Proteins, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6344595d4c4ff10ceeddc97b6414ed06
https://doi.org/10.1096/fj.12-215152