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1Academic Journal
المؤلفون: Matthias Misslinger, Mareike Thea Scheven, Peter Hortschansky, Manuel Sánchez López-Berges, Katharina Heiss, Nicola Beckmann, Thomas Heigl, Martin Hermann, Thomas Krüger, Olaf Kniemeyer, Axel A Brakhage, Hubertus Haas
المصدر: PLoS Genetics, Vol 15, Iss 9, p e1008379 (2019)
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Saskia du Pré, Mike Birch, Derek Law, Nicola Beckmann, Graham E. M. Sibley, Michael J. Bromley, Nick D. Read, Jason D. Oliver
المصدر: Journal of Fungi, Vol 6, Iss 2, p 47 (2020)
مصطلحات موضوعية: antifungal drugs, olorofim, DHODH, pyrimidines, Aspergillus fumigatus, fungal cell morphogenesis, Biology (General), QH301-705.5
وصف الملف: electronic resource
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3Academic Journal
المؤلفون: Anna Johns, Daniel H. Scharf, Fabio Gsaller, Hella Schmidt, Thorsten Heinekamp, Maria Straßburger, Jason D. Oliver, Mike Birch, Nicola Beckmann, Katharine S. Dobb, Jane Gilsenan, Bharatkumar Rash, Elaine Bignell, Axel A. Brakhage, Michael J. Bromley
المصدر: mBio, Vol 8, Iss 4 (2017)
مصطلحات موضوعية: Aspergillus fumigatus, antifungal agents, drug targets, gliotoxin, secondary metabolism, virulence determinants, Microbiology, QR1-502
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2150-7511
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4Academic Journal
المؤلفون: Katharine S Dobb, Sarah J Kaye, Nicola Beckmann, John L Thain, Lubomira Stateva, Mike Birch, Jason D Oliver
المصدر: PLoS ONE, Vol 10, Iss 11, p e0143770 (2015)
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Sixto M. Leal, Sanhita Roy, Chairut Vareechon, Steven deJesus Carrion, Heather Clark, Manuel S. Lopez-Berges, Antonio Di Pietro, Marcus Schrettl, Nicola Beckmann, Bernhard Redl, Hubertus Haas, Eric Pearlman
المصدر: PLoS Pathogens, Vol 9, Iss 7 (2013)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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6Academic Journal
المؤلفون: Sixto M Leal, Sanhita Roy, Chairut Vareechon, Steven deJesus Carrion, Heather Clark, Manuel S Lopez-Berges, Antonio Di Pietro, Marcus Schrettl, Nicola Beckmann, Bernhard Redl, Hubertus Haas, Eric Pearlman
المصدر: PLoS Pathogens, Vol 9, Iss 7, p e1003436 (2013)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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7Academic Journal
المؤلفون: Nicola Beckmann, Lukas Schafferer, Markus Schrettl, Ulrike Binder, Heribert Talasz, Herbert Lindner, Hubertus Haas
المصدر: PLoS ONE, Vol 8, Iss 6, p e67426 (2013)
وصف الملف: electronic resource
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8Academic Journal
المؤلفون: Michael Blatzer, Bridget M Barker, Sven D Willger, Nicola Beckmann, Sara J Blosser, Elizabeth J Cornish, Aurelien Mazurie, Nora Grahl, Hubertus Haas, Robert A Cramer
المصدر: PLoS Genetics, Vol 7, Iss 12, p e1002374 (2011)
وصف الملف: electronic resource
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9Academic Journal
المؤلفون: Markus Schrettl, Nicola Beckmann, John Varga, Thorsten Heinekamp, Ilse D Jacobsen, Christoph Jöchl, Tarek A Moussa, Shaohua Wang, Fabio Gsaller, Michael Blatzer, Ernst R Werner, William C Niermann, Axel A Brakhage, Hubertus Haas
المصدر: PLoS Pathogens, Vol 6, Iss 9, p e1001124 (2010)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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10Academic Journal
المؤلفون: Markus Schrettl, Nicola Beckmann, John Varga, Thorsten Heinekamp, Ilse D. Jacobsen, Tarek A. Moussa, Shaohua Wang, Fabio Gsaller, Michael Blatzer, Ernst R. Werner, C. Niermann, Axel A. Brakhage, Hubertus Haas
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/5e/29/PLoS_Pathog_2010_Sep_30_6(9)_e1001124.tar.gz
وصف الملف: application/zip
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11Academic Journal
المؤلفون: Nicola Beckmann
المساهمون: The Pennsylvania State University CiteSeerX Archives
وصف الملف: application/pdf
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.630.6397; http://ageconsearch.umn.edu/bitstream/53262/2/v39_53262.pdf
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12
المؤلفون: Thomas Heigl, Matthias Misslinger, Mareike Thea Scheven, Axel A. Brakhage, Peter Hortschansky, Hubertus Haas, Martin Hermann, Katharina Heiss, Thomas Krüger, Nicola Beckmann, Olaf Kniemeyer, Manuel Sánchez López-Berges
المصدر: PLoS Genetics, Vol 15, Iss 9, p e1008379 (2019)
PLoS Geneticsمصطلحات موضوعية: Cancer Research, Gene Expression, Yeast and Fungal Models, QH426-470, Pathology and Laboratory Medicine, Biochemistry, Aspergillus fumigatus, Schizosaccharomyces Pombe, 0302 clinical medicine, Gene Expression Regulation, Fungal, Glutaredoxin, Medicine and Health Sciences, Homeostasis, Amino Acids, Genetics (clinical), Fungal Pathogens, 2. Zero hunger, Regulation of gene expression, 0303 health sciences, Xylose, Virulence, biology, Organic Compounds, Monosaccharides, Fungal genetics, Eukaryota, Iron Deficiencies, Iron deficiency, Cell biology, Chemistry, Aspergillus, Aspergillus Fumigatus, Experimental Organism Systems, Fungal Molds, Medical Microbiology, Physical Sciences, Saccharomyces Cerevisiae, Hyperexpression Techniques, Pathogens, Research Article, Iron, Saccharomyces cerevisiae, Carbohydrates, Mycology, Research and Analysis Methods, Microbiology, Fungal Proteins, Saccharomyces, 03 medical and health sciences, Model Organisms, Schizosaccharomyces, DNA-binding proteins, Gene Expression and Vector Techniques, medicine, Genetics, Sulfur Containing Amino Acids, Gene Regulation, Cysteine, Protein Interactions, Molecular Biology Techniques, Microbial Pathogens, Molecular Biology, Transcription factor, Psychological repression, Glutaredoxins, Ecology, Evolution, Behavior and Systematics, 030304 developmental biology, Molecular Biology Assays and Analysis Techniques, Organic Chemistry, Organisms, Fungi, Chemical Compounds, Biology and Life Sciences, Proteins, biology.organism_classification, medicine.disease, Yeast, Regulatory Proteins, Starvation, Animal Studies, 030217 neurology & neurosurgery, Transcription Factors
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13
المؤلفون: Jason David Oliver, Nicola Beckmann, Mariana Cruz Almeida, Mike Birch, Saskia du Pré, Graham Edward Morris Sibley, Alexandra C. Brand, Derek Law, Nick D. Read
المصدر: Antimicrobial Agents and Chemotherapy. 62
مصطلحات موضوعية: 0301 basic medicine, Hyphal growth, Antifungal Agents, Lysis, Hypha, 030106 microbiology, Hyphae, Antifungal drug, Microbial Sensitivity Tests, Piperazines, Microbiology, Aspergillus fumigatus, 03 medical and health sciences, Microscopy, Electron, Transmission, Acetamides, Pyrroles, Pharmacology (medical), Pharmacology, Aspergillus, biology, Chemistry, Spores, Fungal, biology.organism_classification, Culture Media, Pyrimidines, Infectious Diseases, Susceptibility, Germination, Dihydroorotate dehydrogenase
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14
المؤلفون: Nicola Beckmann, Julie Gould, Denise Grässle, Peter Warn, Michaela Lackner, Derek Law, Mike Birch, Verena Naschberger, Cornelia Lass-Flörl, Ulrike Binder
المصدر: The Journal of antimicrobial chemotherapy. 73(11)
مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Male, Posaconazole, Oxidoreductases Acting on CH-CH Group Donors, Antifungal Agents, Itraconazole, 030106 microbiology, Dihydroorotate Dehydrogenase, Microbial Sensitivity Tests, Piperazines, Microbiology, 03 medical and health sciences, Immunocompromised Host, Mice, Amphotericin B, Acetamides, medicine, Animals, Aspergillosis, Pharmacology (medical), Aspergillus terreus, Pyrroles, skin and connective tissue diseases, Dihydroorotate Dehydrogenase Inhibitor, Pharmacology, Voriconazole, Aspergillus, Mice, Inbred ICR, biology, bacterial infections and mycoses, biology.organism_classification, Disease Models, Animal, Infectious Diseases, Pyrimidines, Aspergillus alabamensis, Invasive Fungal Infections, medicine.drug
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15
المؤلفون: Martin J. Slater, Graham Edward Morris Sibley, Jason David Oliver, Laura McEntee, Nathan P. Wiederhold, Nicola Beckmann, Katharine S. Dobb, Michael Bromley, Anthony J. Kennedy, Joanne Livermore, Saskia du Pré, William W. Hope, Mike Birch, Derek Law
المصدر: Oliver, J D, Sibley, G E M, Beckmann, N, Dobb, K S, Slater, M J, McEntee, L, Du Pre, S, Livermore, J, Bromley, M, Wiederhold, N P, Hope, W W, Kennedy, A J, Law, D & Birch, M 2016, ' F901318 represents a novel class of antifungal drug that inhibits dihydroorotate dehydrogenase ', Proceedings of the National Academy of Sciences of the United States of America, vol. 113, no. 45, pp. 12809–12814 . https://doi.org/10.1073/pnas.1608304113
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICAمصطلحات موضوعية: 0301 basic medicine, Drug, chemistry.chemical_classification, Aspergillus, Multidisciplinary, biology, media_common.quotation_subject, 030106 microbiology, Antifungal drug, Pharmacology, Biological Sciences, biology.organism_classification, Aspergillus fumigatus, Microbiology, 03 medical and health sciences, chemistry, Mechanism of action, In vivo, Dihydroorotate dehydrogenase, medicine, Azole, medicine.symptom, media_common
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb38951d6bd7f059c30f0b5a34337ce
https://www.research.manchester.ac.uk/portal/en/publications/f901318-represents-a-novel-class-of-antifungal-drug-that-inhibits-dihydroorotate-dehydrogenase(9cb751b0-e1f3-483a-8bda-db1263b306cc).html -
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المصدر: Frontiers in Microbiology, Vol 6 (2015)
Frontiers in Microbiologyمصطلحات موضوعية: Ornithine, AmcA, Virulence, Aspergillus fumigatus, Iron, lcsh:QR1-502, Siderophores, Microbiology, lcsh:Microbiology, Original Research, Mitochondria
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17
المؤلفون: Sarah J. Kaye, Katharine S. Dobb, John Leslie Thain, Lubomira Stateva, Jason David Oliver, Mike Birch, Nicola Beckmann
المصدر: PLoS ONE, Vol 10, Iss 11, p e0143770 (2015)
PLoS ONEمصطلحات موضوعية: Antifungal Agents, Molecular Sequence Data, Antifungal drug, Gene Expression, Transferases (Other Substituted Phosphate Groups), lcsh:Medicine, Aspergillus fumigatus, Microbiology, law.invention, Substrate Specificity, 03 medical and health sciences, Bacterial Proteins, law, Gene expression, Candida albicans, Amino Acid Sequence, Promoter Regions, Genetic, lcsh:Science, 030304 developmental biology, Sequence Deletion, 0303 health sciences, Multidisciplinary, biology, 030306 microbiology, lcsh:R, Computational Biology, biology.organism_classification, Corpus albicans, 3. Good health, Enzyme Activation, Acyl carrier protein, Phenotype, Biochemistry, Essential gene, Recombinant DNA, biology.protein, lcsh:Q, Carrier Proteins, Sequence Alignment, Research Article
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18
المؤلفون: Falk, Hillmann, Jörg, Linde, Nicola, Beckmann, Michael, Cyrulies, Maria, Strassburger, Thorsten, Heinekamp, Hubertus, Haas, Reinhard, Guthke, Olaf, Kniemeyer, Axel A, Brakhage
المصدر: Molecular microbiology. 93(3)
مصطلحات موضوعية: Sequence Analysis, RNA, Aspergillus fumigatus, Iron, Hyphae, Adaptation, Physiological, Globins, Fungal Proteins, Oxygen, Gene Expression Regulation, Fungal, Fermentation, Mutation, Humans, Transcriptome, Gene Deletion, Transcription Factors
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19
المؤلفون: Sixto M, Leal, Sanhita, Roy, Chairut, Vareechon, Steven deJesus, Carrion, Heather, Clark, Manuel S, Lopez-Berges, Antonio, Di Pietro, Antonio, diPietro, Marcus, Schrettl, Nicola, Beckmann, Bernhard, Redl, Hubertus, Haas, Eric, Pearlman
المصدر: PLoS Pathogens 9(7): e1003436 (2013)
Helvia. Repositorio Institucional de la Universidad de Córdoba
instname
PLoS Pathogens
PLoS Pathogens, Vol 9, Iss 7, p e1003436 (2013)مصطلحات موضوعية: Siderophore, Antifungal Agents, Neutrophils, Siderophores, Biochemistry, Fungal growth, Aspergillus fumigatus, Cornea, Mice, Fusarium, Biology (General), Cells, Cultured, Mice, Knockout, 0303 health sciences, biology, Lactoferrin, Specific Pathogen-Free Organisms, 3. Good health, Infectious Diseases, Medicine, Eye Infections, Fungal, Bacterial Outer Membrane Proteins, Research Article, QH301-705.5, Iron, Immunology, Receptors, Cell Surface, Iron Chelating Agents, Microbiology, 03 medical and health sciences, Hepcidins, Hepcidin, Virology, Fusarium oxysporum, Genetics, Animals, Aspergillosis, Humans, Lectins, C-Type, Fungal diseases, Biology, Molecular Biology, Eye diseases, 030304 developmental biology, Aspergillus, Interleukin-6, 030306 microbiology, Statins, RC581-607, Eye infection, biology.organism_classification, Mice, Inbred C57BL, Ophthalmology, Fusariosis, Mutation, biology.protein, Eyes, Parasitology, Immunologic diseases. Allergy, Lipocalin 1
وصف الملف: application/pdf
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20
المؤلفون: Herbert Lindner, Hubertus Haas, Markus Schrettl, Nicola Beckmann, Lukas Schafferer, Ulrike Binder, Heribert Talasz
المصدر: PLoS ONE, Vol 8, Iss 6, p e67426 (2013)
PLoS ONEمصطلحات موضوعية: Ornithine, Arginine, Transcription, Genetic, Fungal Physiology, Gene Identification and Analysis, Gene Expression, Siderophores, lcsh:Medicine, Mycology, Pathogenesis, Biology, Biochemistry, Microbiology, Ornithine decarboxylase, Molecular Genetics, 03 medical and health sciences, chemistry.chemical_compound, Biosynthesis, Genetics, Polyamines, Gene Regulation, lcsh:Science, Ornithine decarboxylase antizyme, 030304 developmental biology, 2. Zero hunger, 0303 health sciences, Multidisciplinary, 030306 microbiology, Aspergillus fumigatus, lcsh:R, Fungi, Mitochondria, Up-Regulation, Arginase, Host-Pathogen Interaction, chemistry, Ornithine Decarboxylase Inhibitor, Small Molecules, lcsh:Q, Gene Function, Polyamine, Research Article