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1Academic Journal
المؤلفون: Nicholas Hasle, Anthony Cooke, Sanjay Srivatsan, Heather Huang, Jason J Stephany, Zachary Krieger, Dana Jackson, Weiliang Tang, Sriram Pendyala, Raymond J Monnat, Cole Trapnell, Emily M Hatch, Douglas M Fowler
المصدر: Molecular Systems Biology, Vol 16, Iss 6, Pp 1-18 (2020)
مصطلحات موضوعية: genetic screening, microscopy, pharmacology, subcellular localization, transcriptomics, Biology (General), QH301-705.5, Medicine (General), R5-920
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1744-4292
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2Academic Journal
المؤلفون: Vanessa E. Gray, Katherine Sitko, Floriane Z. Ngako Kameni, Miriam Williamson, Jason J. Stephany, Nicholas Hasle, Douglas M. Fowler
المصدر: G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3683-3689 (2019)
مصطلحات موضوعية: amyloid, amyloid beta, deep mutational scanning, protein aggregation, Genetics, QH426-470
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2160-1836
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المؤلفون: Nicholas Hasle, Cole Trapnell, Weiliang Tang, Sanjay Srivatsan, Jason J. Stephany, Emily M. Hatch, Sriram Pendyala, Heather Z Huang, Anthony Cooke, Dana Jackson, Raymond J. Monnat, Douglas M. Fowler, Zachary Krieger
مصطلحات موضوعية: Microscope, Cell, Computational biology, Biology, Cell sorting, Phenotype, law.invention, Transcriptome, medicine.anatomical_structure, law, Gene expression, medicine, Throughput (business), Nuclear localization sequence
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المؤلفون: Kenneth A. Matreyek, Douglas M. Fowler, Nicholas Hasle, Melissa A Chiasson, Jason J. Stephany
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Transgene, Genetic Vectors, Green Fluorescent Proteins, Computational biology, Biology, Viral vector, Recombinases, Mice, 03 medical and health sciences, Negative selection, 0302 clinical medicine, Genetics, Recombinase, Animals, Humans, Genomic library, Multiplex, Transgenes, Gene Library, 030304 developmental biology, Recombination, Genetic, 0303 health sciences, Cell growth, Tumor Suppressor Proteins, Lentivirus, HEK 293 cells, Oncogenes, Recombinant Proteins, Luminescent Proteins, HEK293 Cells, NIH 3T3 Cells, Methods Online, Biological Assay, HT29 Cells, 030217 neurology & neurosurgery, Plasmids
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5
المؤلفون: Nicholas, Hasle, Kenneth A, Matreyek, Douglas M, Fowler
المصدر: Cold Spring Harb Perspect Med
مصطلحات موضوعية: Phenotype, Mutation, Missense, PTEN Phosphohydrolase, High-Throughput Nucleotide Sequencing, Humans, Protein Processing, Post-Translational, Signal Transduction, Perspectives
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6
المؤلفون: Nicholas Hasle, Miriam Williamson, Floriane Z. Ngako Kameni, Katherine A. Sitko, Jason J. Stephany, Douglas M. Fowler, Vanessa E. Gray
المصدر: G3: Genes, Genomes, Genetics, Vol 9, Iss 11, Pp 3683-3689 (2019)
G3: Genes|Genomes|Geneticsمصطلحات موضوعية: Amyloid, Amyloid beta, Context (language use), Investigations, QH426-470, Protein aggregation, Biology, 010402 general chemistry, Fibril, Protein Aggregation, Pathological, 01 natural sciences, protein aggregation, 03 medical and health sciences, 0302 clinical medicine, deep mutational scanning, Genetics, Humans, Proline, Molecular Biology, Genetics (clinical), Gene Library, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Amyloid beta-Peptides, Mutagenesis, amyloid, Alanine scanning, Peptide Fragments, In vitro, Yeast, 0104 chemical sciences, Amino acid, amyloid beta, Amino Acid Substitution, chemistry, Mutation, biology.protein, Biophysics, 030217 neurology & neurosurgery
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7
المؤلفون: Kenneth A. Matreyek, Douglas M. Fowler, Nicholas Hasle
المصدر: Cold Spring Harbor Perspectives in Medicine. 9:a036228
مصطلحات موضوعية: 0301 basic medicine, Mutation, biology, Computational biology, medicine.disease_cause, Subcellular localization, Phenotype, General Biochemistry, Genetics and Molecular Biology, law.invention, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, law, 030220 oncology & carcinogenesis, biology.protein, medicine, Missense mutation, PTEN, Suppressor, Tensin, Signal transduction
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8
المؤلفون: Nicholas Hasle, Savitha Kalidas, Mehdi Labaied, Margaret A. Phillips, Igor Cestari, Kenneth Stuart, Severine Monnerat, Qiong Li, Marilyn Parsons, Sandesh Regmi
المصدر: Eukaryotic cell. 13(4)
مصطلحات موضوعية: Trypanosoma brucei brucei, Protozoan Proteins, Trypanosoma brucei, Microbiology, Amino Acyl-tRNA Synthetases, chemistry.chemical_compound, Cytosol, RNA interference, Gene expression, parasitic diseases, Drug Discovery, RNA, Messenger, RNA, Small Interfering, Molecular Biology, Gene, chemistry.chemical_classification, Gene knockdown, biology, Aminoacyl tRNA synthetase, Drug discovery, Cell Cycle, General Medicine, Articles, biology.organism_classification, Trypanocidal Agents, Mitochondria, Enzyme, chemistry, Biochemistry, Gene Expression Regulation, Gene Knockdown Techniques, Fatty Alcohols, Signal Transduction
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9
المؤلفون: Megan M. Maurano, Thomas D. Bird, Nicholas Hasle, Gregory S. Olson, Marshall S. Horwitz, Jay Shendure, Max L. Dougherty, John Lazar, Desiree A. Marshall, Karina Diaz, Theodore A Gobillot, Maria T. Nelson, Eli Grunblatt, Jason C. Klein, Daniel J. P. Lawrence, C. Dirk Keene, Sanjay Srivatsan
المصدر: Cold Spring Harbor Molecular Case Studies
مصطلحات موضوعية: Research Report, Male, 0301 basic medicine, Pathology, Hepatosplenomegaly, progressive encephalopathy, Genome-wide association study, 0302 clinical medicine, falls, progressive psychomotor deterioration, Niemann-Pick Diseases, central nervous system degeneration, Membrane Glycoproteins, neurodegeneration, Intracellular Signaling Peptides and Proteins, atrophy/degeneration affecting the cerebrum, Brain, Neurodegenerative Diseases, Neurofibrillary Tangles, Niemann-Pick Disease, Type C, General Medicine, 3. Good health, progressive language deterioration, medicine.symptom, medicine.medical_specialty, Ataxia, Lipid storage disorder, Mutation, Missense, Cerebellar Purkinje cell, 03 medical and health sciences, Atrophy, Niemann-Pick C1 Protein, medicine, Humans, progressive forgetfulness, Genetic Testing, Base Sequence, Whole Genome Sequencing, business.industry, slowed slurred speech, Lipid metabolism, medicine.disease, neuronal loss in central nervous system, 030104 developmental biology, social and occupational deterioration, Mutation, Dementia, hepatosplenomegaly, NPC1, Carrier Proteins, business, 030217 neurology & neurosurgery
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10
المؤلفون: Karen Sommer, Jordan Jarjour, Jaya Sahni, Malika Hale, Baeckseung Lee, David J. Rawlings, Alexandra E. Grier, Guillermo S. Romano Ibarra, Nicholas Hasle, Honaker Yuchi Chiang, Andrew M. Scharenberg, Iram F. Khan, Alexander Astrakhan
المصدر: Molecular Therapy. 24:S158
مصطلحات موضوعية: Pharmacology, Biology, Virology, Chimeric antigen receptor, In vitro, CD19, Cell biology, Cell therapy, Gene cassette, Cell culture, Drug Discovery, Genetics, biology.protein, Molecular Medicine, Human genome, Homologous recombination, Molecular Biology