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1Academic Journal
المؤلفون: Nicholas G. Lamson, Andrew J. Pickering, Jeffrey Wyckoff, Priya Ganesh, Elizabeth A. Calle, Joelle P. Straehla, Paula T. Hammond
المصدر: Bioengineering & Translational Medicine, Vol 9, Iss 4, Pp n/a-n/a (2024)
مصطلحات موضوعية: blood–brain barrier, drug delivery, in vitro models, intracellular trafficking, intravital imaging, layer‐by‐layer, Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2380-6761
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2Academic JournalLong‐term daily oral administration of intestinal permeation enhancers is safe and effective in mice
المؤلفون: Katherine C. Fein, John P. Gleeson, Kyle Cochran, Nicholas G. Lamson, Rose Doerfler, Jilian R. Melamed, Kathryn A. Whitehead
المصدر: Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)
مصطلحات موضوعية: intestinal epithelium, oral drug delivery, permeation enhancer, Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2380-6761
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3Academic Journal
المؤلفون: Kyle E. Cochran, Nicholas G. Lamson, Kathryn A. Whitehead
المصدر: PeerJ, Vol 8, p e8681 (2020)
مصطلحات موضوعية: Inflammatory bowel disease, IBD, Colitis, Dextran sodium sulfate, Dextran sulfate sodium, DSS, Medicine, Biology (General), QH301-705.5
وصف الملف: electronic resource
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4
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5A Potent Branched-Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing In Vivo
المؤلفون: Rebecca L. Ball, Jilian R. Melamed, Khalid A. Hajj, Kathryn A. Whitehead, Namit Chaudhary, Saigopalakrishna S. Yerneni, Nicholas G. Lamson
المصدر: Nano Lett
مصطلحات موضوعية: Bioengineering, 02 engineering and technology, Article, Mice, In vivo, Animals, General Materials Science, Luciferase, RNA, Messenger, Guide RNA, Subgenomic mRNA, Gene Editing, Messenger RNA, Chemistry, Mechanical Engineering, Liver cell, Gene Transfer Techniques, Translation (biology), General Chemistry, 021001 nanoscience & nanotechnology, Condensed Matter Physics, Lipids, Cell biology, Nanoparticles, 0210 nano-technology, mCherry
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6
المؤلفون: Katherine C. Fein, Shiyuan Zheng, Kathryn A. Whitehead, Nicholas G. Lamson, Kris Noel Dahl, Kirill Lavrenyuk
المصدر: ACS Biomaterials Science & Engineering. 6:367-374
مصطلحات موضوعية: 0206 medical engineering, Biomedical Engineering, 02 engineering and technology, Permeability, Piperazines, Biomaterials, chemistry.chemical_compound, Myosin, medicine, Humans, Cytoskeleton, Tight junction, Cadherin, Epithelial Cells, Permeation, Cadherins, 021001 nanoscience & nanotechnology, 020601 biomedical engineering, Epithelium, Piperazine, medicine.anatomical_structure, Pharmaceutical Preparations, chemistry, Drug delivery, Biophysics, Caco-2 Cells, 0210 nano-technology
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7
المؤلفون: Tejal A. Desai, Karen E. Samy, Deanna L. Kroetz, Kathryn A. Whitehead, Elizabeth S. Levy, Nicholas G. Lamson
المصدر: Eur J Pharm Biopharm
مصطلحات موضوعية: Male, Pharmaceutical Science, ATP-binding cassette transporter, 02 engineering and technology, Pharmacology, Inbred C57BL, Subfamily G, 030226 pharmacology & pharmacy, Rhodamine 123, Polyethylene Glycols, Mice, chemistry.chemical_compound, 0302 clinical medicine, ATP Binding Cassette Transporter, Subfamily G, Member 2, Pharmacology & Pharmacy, Intestinal Mucosa, Cancer, Tumor, Hydrogels, Pharmacology and Pharmaceutical Sciences, General Medicine, 021001 nanoscience & nanotechnology, Intestines, Subfamily B, 5.1 Pharmaceuticals, Drug delivery, Development of treatments and therapeutic interventions, 0210 nano-technology, Biotechnology, Member 2, Boron Compounds, Member 1, Passive transport, ATP Binding Cassette Transporter, Biological Availability, Article, Cell Line, 03 medical and health sciences, In vivo, Cell Line, Tumor, Animals, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Biological Transport, Prazosin, Bioavailability, Mice, Inbred C57BL, Intestinal Absorption, Solubility, chemistry, Caco-2, Mediated transport, Caco-2 Cells
وصف الملف: application/pdf
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8
المصدر: Nature Biomedical Engineering. 4:84-96
مصطلحات موضوعية: 0301 basic medicine, Intestinal permeability, Tight junction, Chemistry, Insulin, medicine.medical_treatment, Biomedical Engineering, Medicine (miscellaneous), Bioengineering, Pharmacology, medicine.disease, Computer Science Applications, 03 medical and health sciences, Subcutaneous injection, 030104 developmental biology, 0302 clinical medicine, Permeability (electromagnetism), Diabetes mellitus, medicine, Exenatide, 030217 neurology & neurosurgery, Intracellular, Biotechnology, medicine.drug
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9
المؤلفون: Alexandra N. Newby, Katherine C. Fein, Ahuja, Kolodieznyi D, Xian S, Kathryn A. Whitehead, Rebecca L. Ball, Zhang A, Berger A, Brigitte F. Schmidt, John P. Gleeson, Nicholas G. Lamson, Melamed, Silva Gl, Namit Chaudhary, Kanika Suri, Cochran K
مصطلحات موضوعية: 2. Zero hunger, 0303 health sciences, Gastrointestinal tract, Natural product, business.industry, Insulin, medicine.medical_treatment, Pharmacology, In vitro, Pelargonidin, 3. Good health, 03 medical and health sciences, chemistry.chemical_compound, Subcutaneous injection, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Pharmacodynamics, medicine, business, Enhancer, 030304 developmental biology
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10
المصدر: Pharmaceutical Research. 36
مصطلحات موضوعية: Male, Surface Properties, Administration, Oral, Pharmaceutical Science, 02 engineering and technology, 030226 pharmacology & pharmacy, Permeability, Trim, Tight Junctions, Mice, 03 medical and health sciences, 0302 clinical medicine, Gene expression, Monolayer, Animals, Humans, Pharmacology (medical), Intestinal Mucosa, Cells, Cultured, Cell Proliferation, Pharmacology, Tight junction, Chemistry, Organic Chemistry, Dextrans, 021001 nanoscience & nanotechnology, Intestinal epithelium, In vitro, Cell biology, Mice, Inbred C57BL, Drug Liberation, Caco-2, Molecular Medicine, Collagen, Caco-2 Cells, 0210 nano-technology, Fetal bovine serum, Biotechnology
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المصدر: Nature biomedical engineering. 4(1)
مصطلحات موضوعية: Cell Membrane Permeability, Administration, Oral, Silicon Dioxide, Cell Line, Tight Junctions, Mice, Inbred C57BL, Diabetes Mellitus, Type 1, Drug Delivery Systems, Animals, Exenatide, Insulin, Nanoparticles, Intestinal Mucosa, Particle Size
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13Academic Journal
المصدر: PeerJ; Mar2020, p1-14, 14p
مصطلحات موضوعية: DEXTRAN sulfate, INFLAMMATORY bowel diseases, SODIUM sulfate, SKIN permeability, INTESTINES, COLITIS, COLON (Anatomy), MICE
مصطلحات جغرافية: UNITED States
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14
المؤلفون: Kathryn A. Whitehead, Katherine C. Fein, Nicholas G. Lamson
المصدر: Pharmaceutical research. 34(6)
مصطلحات موضوعية: 0301 basic medicine, Cell Survival, Pharmaceutical Science, Administration, Oral, Phenylpiperazine, 02 engineering and technology, Absorption (skin), Pharmacology, Permeability, Piperazines, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, Humans, Pharmacology (medical), Intestinal Mucosa, Cytotoxicity, Fluorescent Dyes, Molecular Structure, Organic Chemistry, Optical Imaging, Biological Transport, Permeation, 021001 nanoscience & nanotechnology, Intestinal epithelium, Calcein, 030104 developmental biology, chemistry, Intestinal Absorption, Paracellular transport, Toxicity, Biophysics, Molecular Medicine, Caco-2 Cells, 0210 nano-technology, Biotechnology
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15
المصدر: Molecular pharmaceutics. 13(2)
مصطلحات موضوعية: 0301 basic medicine, Cell Membrane Permeability, Pharmaceutical Science, Administration, Oral, 030226 pharmacology & pharmacy, Piperazines, 03 medical and health sciences, 0302 clinical medicine, Intestinal mucosa, Drug Discovery, Humans, Intestinal Mucosa, Enhancer, Cell Proliferation, Chemistry, Translation (biology), Biological Transport, Permeation, Hydrogen-Ion Concentration, Intestinal epithelium, 030104 developmental biology, Biochemistry, Caco-2, Molecular Medicine, Caco-2 Cells, Flux (metabolism), Intracellular
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16Academic Journal
المؤلفون: Andrew J. Pickering, Nicholas G. Lamson, Michael H. Marand, Wei Hwang, Joelle P. Straehla, Paula T. Hammond
مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Pharmacology, Biotechnology, Cancer, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, various therapeutic applications, three times larger, target cellular uptake, prevent local recurrence, pegylated polyelectrolytes improved, locally delivered therapies, harsh ionic environment, flow cytometric analysis, effective surface chemistries, distinct cellular outcomes, design drug carriers, complete surgical resection, coadsorbing either polymer, administering therapeutics directly, broad spatial distribution, modular delivery system, lbl nps compared, targeting glioblastoma cells, brain tumor tissue, np distribution due, glioblastoma targeting