المؤلفون: Nicholas B. Hastings, Xiaohai Wang, Lixin Song, Brent D. Butts, Diane Grotz, Richard Hargreaves, J. Fred Hess, Kwok-Lam Karen Hong, Cathy Ruey-Ruey Huang, Lynn Hyde, Maureen Laverty, Julie Lee, Diane Levitan, Sherry X. Lu, Maureen Maguire, Veeravan Mahadomrongkul, Ernest J. McEachern, Xuesong Ouyang, Thomas W. Rosahl, Harold Selnick, Michaela Stanton, Giuseppe Terracina, David J. Vocadlo, Ganfeng Wang, Joseph L. Duffy, Eric M. Parker, Lili Zhang

المصدر: Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: Tau, OGA, O-GlcNAc, Alzheimer’s disease, Tauopathy, Neurodegeneration, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13024-017-0181-0; https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/1ce645702743455b9fc3c2ca7c604062

المؤلفون: John A. Morrow, Robert Mazzola, Cristian Salinas, Eric D. Hostetler, Stefania Risso, Fiona Thomson, Tjerk Bueters, Nicholas B. Hastings, Jenny Wai, Sony Agrawal, Liza Gantert, Brian C. Magliaro, Paul McQuade, Zhizhen Zeng, Marie A. Holahan, David Hesk, Melissa Egbertson, Jeffrey W. Schubert, Ling Tong, Robert Gomez, Jongrock Kong, Aniket Joshi, Frederick J. Monsma, David M. Tellers, Kristen L.G. Jones, Jason M. Uslaner, Jing Liao, Patricia Miller, Michelle Smith, Oleg Selyutin, Kerry Riffel, Xiaolei Gao, Scott T. Harrison, Zhaoyang Meng, James Mulhearn, Michael Man-Chu Lo, Wenping Li, Michael T. Rudd, Barbara Hanney, Mona Purcell, Jianming Bao, Hyking Haley

المصدر: Journal of Medicinal Chemistry. 63:2411-2425

مصطلحات موضوعية: Agonist, 0303 health sciences, Carbachol, medicine.diagnostic_test, Chemistry, medicine.drug_class, Allosteric regulation, Pharmacology, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, In vivo, Positron emission tomography, Drug Discovery, Muscarinic acetylcholine receptor, medicine, Molecular Medicine, Receptor, Preclinical imaging, 030304 developmental biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::949c4dbede58ed2de44d27f608635d36
https://doi.org/10.1021/acs.jmedchem.9b01406

المؤلفون: Qiaoling Deng, Feroze Ujjainwalla, F. Anthony Romero, Jenna L. Terebetski, Jerry Di Salvo, Ying Li, Dorina Trusca, Ming Wang, Nicholas B. Hastings, Remond Moningka, Vincent Tong, Zhiqiang Guo, Richard G. Ball

المصدر: Bioorganicmedicinal chemistry letters. 30(23)

مصطلحات موضوعية: Receptors, Neuropeptide, Benzimidazole, Stereochemistry, Dissociation rate, Clinical Biochemistry, Fragment-based lead discovery, Pharmaceutical Science, Neuropeptide, CHO Cells, 01 natural sciences, Biochemistry, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Structure-Activity Relationship, Cricetulus, Drug Discovery, Animals, Humans, Neuropeptide B/W receptor, Molecular Biology, G protein-coupled receptor, Molecular Structure, 010405 organic chemistry, Chemistry, Organic Chemistry, Small molecule, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Benzimidazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e4a6a9cbe7d66ea64b2f90c58c7963
https://pubmed.ncbi.nlm.nih.gov/32898693

المؤلفون: Adam B Weinglass, Nicholas B Hastings, Bradley S Sherborne, Jennifer M. Johnston, Andrew D Howard, Maria Webb, Steven L. Colletti, Clemens Vonrhein, Kevin J. Lumb, Srivanya Tummala, Frank K Brown, Jennifer Hadix, Hubert Josien, Stephen M. Soisson, Guo Yan, Harry R. Chobanian, John Wang, Michael W. Miller, Brande Thomas-Fowlkes, Dawn L. Hall, Jeffrey D. Hermes, Thu Ho, Barbara Pio, Payal R. Sheth, Sujata Sharma, Maria Kornienko, Samantha J Allen, Sangita B. Patel, Jerry Di Salvo, Sarah Souza, Gérard Bricogne, Christopher W Plummer, Jun Lu, Noel Byrne

المصدر: Nature Structural & Molecular Biology. 24:570-577

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Binding Sites, biology, Protein Conformation, Allosteric regulation, Cooperativity, Crystallography, X-Ray, Partial agonist, Receptors, G-Protein-Coupled, 03 medical and health sciences, Transmembrane domain, 030104 developmental biology, Allosteric Regulation, Allosteric enzyme, Biochemistry, Structural Biology, Free fatty acid receptor 1, biology.protein, Free fatty acid receptor, Biophysics, Humans, Binding site, Molecular Biology, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4bc0224021f59b552cc8f44381dfe9
https://doi.org/10.1038/nsmb.3417

المؤلفون: Ling, Tong, Wenping, Li, Michael Man-Chu, Lo, Xiaolei, Gao, Jenny Miu-Chen, Wai, Michael, Rudd, David, Tellers, Aniket, Joshi, Zhizhen, Zeng, Patricia, Miller, Cristian, Salinas, Kerry, Riffel, Hyking, Haley, Mona, Purcell, Marie, Holahan, Liza, Gantert, Jeffrey W, Schubert, Kristen, Jones, James, Mulhearn, Melissa, Egbertson, Zhaoyang, Meng, Barbara, Hanney, Robert, Gomez, Scott T, Harrison, Paul, McQuade, Tjerk, Bueters, Jason, Uslaner, John, Morrow, Fiona, Thomson, Jongrock, Kong, Jing, Liao, Oleg, Selyutin, Jianming, Bao, Nicholas B, Hastings, Sony, Agrawal, Brian C, Magliaro, Frederick J, Monsma, Michelle D, Smith, Stefania, Risso, David, Hesk, Eric, Hostetler, Robert, Mazzola

المصدر: Journal of medicinal chemistry. 63(5)

مصطلحات موضوعية: Cricetulus, Allosteric Regulation, Receptor, Muscarinic M4, Pyridines, Positron-Emission Tomography, Animals, Humans, Neurodegenerative Diseases, CHO Cells, Carbon Radioisotopes, Muscarinic Agonists, Macaca mulatta

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::cd3ef3c047c980065bd64efde0a0b7e9
https://pubmed.ncbi.nlm.nih.gov/32101422

المؤلفون: Patima Tanapat, Nicholas B. Hastings, Alison J. Reeves, Elizabeth Gould

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.jneurosci.org/content/19/14/5792.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.323.4106; http://www.jneurosci.org/content/19/14/5792.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.323.4106
http://www.jneurosci.org/content/19/14/5792.full.pdf

المؤلفون: Julie Lee, Sherry X. Lu, Maureen Laverty, Brent D. Butts, Diane Grotz, Richard Hargreaves, Michaela C. Stanton, J. Fred Hess, Ernest J. McEachern, Ganfeng Wang, Giuseppe Terracina, Diane Levitan, Xuesong Ouyang, Lynn A. Hyde, Lili Zhang, Joseph L. Duffy, Harold G. Selnick, Thomas W. Rosahl, Kwok-Lam Karen Hong, Nicholas B. Hastings, Cathy Ruey-Ruey Huang, David J. Vocadlo, Xiaohai Wang, Lixin Song, Veeravan Mahadomrongkul, Maureen Maguire, Eric M. Parker

المصدر: Molecular Neurodegeneration
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)

مصطلحات موضوعية: 0301 basic medicine, Transgene, Tau protein, Hyperphosphorylation, Mice, Transgenic, tau Proteins, lcsh:Geriatrics, lcsh:RC346-429, Serine, 03 medical and health sciences, Cellular and Molecular Neuroscience, Mice, 0302 clinical medicine, Cerebrospinal fluid, mental disorders, medicine, Animals, Neurodegeneration, Molecular Biology, lcsh:Neurology. Diseases of the nervous system, Pyrans, biology, Chemistry, OGA, medicine.disease, Molecular medicine, beta-N-Acetylhexosaminidases, Cell biology, lcsh:RC952-954.6, Tauopathy, Thiazoles, 030104 developmental biology, Tauopathies, biology.protein, O-GlcNAc, Neurology (clinical), Tau, Neuroscience, Alzheimer’s disease, Protein Processing, Post-Translational, 030217 neurology & neurosurgery, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d5f4d3ff660dac7240ab2430a4c718
http://europepmc.org/articles/PMC5437664

المؤلفون: Patima Tanapat, Nicholas B. Hastings, Malika I. Seth, Elizabeth Gould, Tracy Rydel

المصدر: The Journal of Comparative Neurology. 452:324-333

مصطلحات موضوعية: Male, Antimetabolites, Biology, Hippocampal formation, Hippocampus, Rats, Sprague-Dawley, Pregnancy, Neural Pathways, medicine, Animals, Axon, Hippocampal mossy fiber, Neurons, General Neuroscience, Dentate gyrus, Granule (cell biology), Granule cell, Immunohistochemistry, Retrograde tracing, Axons, Rats, medicine.anatomical_structure, Bromodeoxyuridine, nervous system, Dentate Gyrus, Mossy Fibers, Hippocampal, Excitatory postsynaptic potential, Female, Neuroscience, Biomarkers, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d4a14013255024129e336b4a7b6249
https://doi.org/10.1002/cne.10386

المؤلفون: Nicholas B. Hastings, Patima Tanapat, Elizabeth Gould

المصدر: Clinical Neuroscience Research. 1:175-182

مصطلحات موضوعية: Dentate gyrus, Neurogenesis, Biology, Granule cell, Subgranular zone, Psychiatry and Mental health, Neuropsychology and Physiological Psychology, medicine.anatomical_structure, nervous system, Neurology, Neuroplasticity, medicine, Biological neural network, Ultrastructure, Neurology (clinical), Progenitor cell, Neuroscience, Biological Psychiatry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b40a51d64b77d3ab9097b646a422b22d
https://doi.org/10.1016/s1566-2772(01)00003-2

المؤلفون: Elizabeth Gould, Patima Tanapat, Tracy Rydel, Liisa A.M. Galea, Nicholas B. Hastings

المصدر: The Journal of Comparative Neurology. 437:496-504

مصطلحات موضوعية: DNA Replication, Male, Citrus, medicine.medical_specialty, medicine.medical_treatment, Foxes, Biology, Calbindin, Rats, Sprague-Dawley, chemistry.chemical_compound, Corticosterone, Internal medicine, Administration, Inhalation, medicine, Animals, Lamiaceae, Microscopy, Confocal, Adrenal cortex, General Neuroscience, Adrenalectomy, Dentate gyrus, Neurogenesis, Rats, Thiazoles, Endocrinology, medicine.anatomical_structure, chemistry, Dentate Gyrus, Odorants, Adrenal Cortex, biology.protein, NeuN, Cell Division, Stress, Psychological, Glucocorticoid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c21200d054ca30937ba12f470f89404a
https://doi.org/10.1002/cne.1297

المؤلفون: Patima Tanapat, Nicholas B. Hastings, Elizabeth Gould

المصدر: The Neuroscientist. 6:315-325

مصطلحات موضوعية: 0301 basic medicine, General Neuroscience, Period (gene), Dentate gyrus, Neurogenesis, Hippocampus, 03 medical and health sciences, Neural activity, 030104 developmental biology, 0302 clinical medicine, Neuroplasticity, Functional significance, Neurology (clinical), Psychology, Neuroscience, 030217 neurology & neurosurgery, Brain function

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9159f8fda814fecc9951aed83fd327f6
https://doi.org/10.1177/107385840000600506

المؤلفون: Elizabeth Gould, Nicholas B. Hastings

المصدر: The Journal of Comparative Neurology. 413:146-154

مصطلحات موضوعية: General Neuroscience, Dentate gyrus, Neurogenesis, Granule (cell biology), Hippocampal formation, Biology, Deoxyuridine, Cell biology, chemistry.chemical_compound, nervous system, chemistry, Fast blue, Neuroscience, Mitosis, Bromodeoxyuridine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5ed3f18ddc531ff88872ba8e23fe5a1e
https://doi.org/10.1002/(sici)1096-9861(19991011)413:1<146::aid-cne10>3.0.co;2-b

المؤلفون: Elizabeth Gould, Nicholas B. Hastings

المصدر: Nature Medicine. 9:264-266

مصطلحات موضوعية: medicine.medical_specialty, Cellular differentiation, Neurogenesis, Growth differentiation factor, General Medicine, Biology, General Biochemistry, Genetics and Molecular Biology, Cell biology, Endocrinology, medicine.anatomical_structure, Precursor cell, Internal medicine, medicine, Neuron, Olfactory epithelium

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::94c839df9bf69106f286c0864bfb56b3
https://doi.org/10.1038/nm0303-264

المؤلفون: Dorina Trusca, Feroze Ujjainwalla, Ying Lei, Richard G. Ball, Zhiqiang Guo, Jerry Di Salvo, Deng Qiaolin, F. Anthony Romero, Jenna L. Terebetski, Nicholas B. Hastings, Ming Wang, Remond Moningka, Vincent Tong

المصدر: Bioorganicmedicinal chemistry letters. 22(2)

مصطلحات موضوعية: Models, Molecular, Receptors, Neuropeptide, Benzylamines, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Stereoisomerism, Crystallography, X-Ray, Biochemistry, Piperazines, Receptors, G-Protein-Coupled, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Drug Discovery, Structure–activity relationship, Animals, Humans, Receptor, Molecular Biology, Piperazine, G protein-coupled receptor, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Ligand binding assay, Organic Chemistry, Antagonist, Small molecule, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::967b9be7ac290cc1937fe99cfdc059e8
https://pubmed.ncbi.nlm.nih.gov/22197390

المؤلفون: Edward M. Jakubowski, Bhupendra P. Doctor, Robert J. Mioduszewski, Wei Sun, Paul A. Dabisch, Ashima Saxena, S. W. Hulet, Nicholas B. Hastings

المصدر: Biochemical pharmacology. 82(12)

مصطلحات موضوعية: Male, Sarin, Heart malformation, Swine, Pharmacology, Biochemistry, chemistry.chemical_compound, Seizures, medicine, Animals, Humans, Chemical Warfare Agents, Butyrylcholinesterase, Nerve agent, Inhalation exposure, Dose-Response Relationship, Drug, Chemistry, Lethal dose, Arrhythmias, Cardiac, Blood chemistry, Anesthesia, Toxicity, Acetylcholinesterase, Swine, Miniature, Respiratory Insufficiency, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ccf0219919ef6cab60b5c243cea69ee
https://pubmed.ncbi.nlm.nih.gov/21968035

المؤلفون: S. W. Hulet, Edward M. Jakubowski, Paul A. Dabisch, Bhupendra P. Doctor, Wei Sun, Robert J. Mioduszewski, Ashima Saxena, Nicholas B. Hastings

المصدر: Chemico-biological interactions. 175(1-3)

مصطلحات موضوعية: Male, Sarin, Aché, Swine, Antidotes, Biological Availability, Pharmacology, Toxicology, chemistry.chemical_compound, Bolus (medicine), medicine, Animals, Humans, Chemical Warfare Agents, Butyrylcholinesterase, Nerve agent, Inhalation exposure, Inhalation, Chemistry, Organophosphate, General Medicine, language.human_language, Anesthesia, language, Swine, Miniature, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5b3cb802688def729c05546353a0147
https://pubmed.ncbi.nlm.nih.gov/18597747

المؤلفون: Nicholas B. Hastings, Patima Tanapat, Elizabeth Gould

المصدر: The Journal of comparative neurology. 481(3)

مصطلحات موضوعية: medicine.medical_specialty, Time Factors, medicine.drug_class, Ovariectomy, Cell, Down-Regulation, Estrous Cycle, Histones, Rats, Sprague-Dawley, chemistry.chemical_compound, Internal medicine, medicine, Animals, Estrogen Receptor beta, Gonadal Steroid Hormones, Progesterone, Cell Proliferation, Neurons, Glial fibrillary acidic protein, biology, Dose-Response Relationship, Drug, Cell growth, General Neuroscience, Dentate gyrus, Stem Cells, Estrogen Receptor alpha, Estrogens, Rats, Endocrinology, medicine.anatomical_structure, chemistry, Estrogen, Dentate Gyrus, Ovariectomized rat, biology.protein, Female, Bromodeoxyuridine, Biomarkers, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d779ff96bf9b9d5a707b5cdaf5bab3a
https://pubmed.ncbi.nlm.nih.gov/15593136

المؤلفون: Patima Tanapat, Nicholas B. Hastings, Elizabeth Gould

مصطلحات موضوعية: Nervous system, Synapse, medicine.anatomical_structure, Neurogenesis, medicine, Biological neural network, Endocrine system, Biology, Neuroscience, Function (biology), Epithelium, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dae58ecb3bc6485a2ae8daa86e20cbbc
https://doi.org/10.1016/b978-012532104-4/50080-9

المؤلفون: Alison J. Reeves, Nicholas B. Hastings, Patima Tanapat, Elizabeth Gould

مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.drug_class, Ovariectomy, Subventricular zone, Nerve Tissue Proteins, Biology, Hippocampal formation, Calbindin, Hippocampus, Article, Rats, Sprague-Dawley, chemistry.chemical_compound, Estrus, Internal medicine, medicine, Animals, Estrous cycle, Neurons, Sex Characteristics, Microscopy, Confocal, Estradiol, General Neuroscience, Dentate gyrus, Rats, medicine.anatomical_structure, Endocrinology, chemistry, Bromodeoxyuridine, Estrogen, Dentate Gyrus, Female, Neuroglia, Cell Division, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fefb2850afd9256be696abfad6ee1828
https://europepmc.org/articles/PMC6783062/

المؤلفون: Tracey J. Shors, Nicholas B. Hastings, Elizabeth Gould, Patima Tanapat

المصدر: Trends in cognitive sciences. 3(5)

مصطلحات موضوعية: Brain region, Neuropsychology and Physiological Psychology, Mechanism (biology), Cognitive Neuroscience, education, Neurogenesis, Hippocampus, Experimental and Cognitive Psychology, Hippocampal function, Hippocampal formation, Psychology, Neuroscience, Associative learning

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f956ffad75755de7309f4a348e4e8c8f
https://pubmed.ncbi.nlm.nih.gov/10322475