المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/dataset/DataSheet_4_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_pdf/14877471

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s004

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/dataset/DataSheet_2_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_pdf/14877465

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s002

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/figure/Image_4_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_tiff/14877483

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s008

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/figure/Image_1_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_tiff/14877474

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s005

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/figure/Image_2_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_tiff/14877477

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s006

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/figure/Image_5_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_tiff/14877486

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s009

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/figure/Image_3_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_tiff/14877480

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s007

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/dataset/Table_1_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_docx/14877489

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s010

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/dataset/DataSheet_1_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_pdf/14877462

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s001

المؤلفون: Daniel Ellis (8970353), Natalie Brunette (11046342), Katharine H. D. Crawford (10573373), Alexandra C. Walls (11046345), Minh N. Pham (7380416), Chengbo Chen (11046348), Karla-Luise Herpoldt (1500412), Brooke Fiala (11046351), Michael Murphy (80941), Deleah Pettie (11046354), John C. Kraft (11046357), Keara D. Malone (11046360), Mary Jane Navarro (11046363), Cassandra Ogohara (11046366), Elizabeth Kepl (11046369), Rashmi Ravichandran (11046372), Claire Sydeman (11046375), Maggie Ahlrichs (11046378), Max Johnson (3643675), Alyssa Blackstone (11046381), Lauren Carter (628050), Tyler N. Starr (3276999), Allison J. Greaney (11046384), Kelly K. Lee (9740516), David Veesler (11046387), Jesse D. Bloom (8796629), Neil P. King (3365492)

مصطلحات موضوعية: Immunology, Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies), Autoimmunity, Cellular Immunology, Humoural Immunology and Immunochemistry, Immunogenetics (incl. Genetic Immunology), Innate Immunity, Transplantation Immunology, Tumour Immunology, Immunology not elsewhere classified, Genetic Immunology, Animal Immunology, Veterinary Immunology, SARS-CoV-2, vaccine, nanoparticle, antigen stabilization, receptor-binding domain, computational protein design, deep mutational scanning

Relation: https://figshare.com/articles/dataset/DataSheet_3_Stabilization_of_the_SARS-CoV-2_Spike_Receptor-Binding_Domain_Using_Deep_Mutational_Scanning_and_Structure-Based_Design_pdf/14877468

الاتاحة: https://doi.org/10.3389/fimmu.2021.710263.s003