المؤلفون: Ehsan Mohammadifar (3593738), Matteo Gasbarri (11371921), Valeria Cagno (1779763), Katharina Achazi (562805), Caroline Tapparel (74799), Rainer Haag (1385424), Francesco Stellacci (824625)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Pharmacology, Biotechnology, Ecology, Mental Health, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, stepping stone toward, rsv ), giving, viral dna upon, like gold nanoparticles, virucidal activity leads, polyanionic dendritic polymers, respiratory syncytial virus, micromolar inhibition concentration, showed nanomolar activity, like compounds renders, virus inhibition mechanism, nanomolar inhibition concentration, long hydrophobic linkers, almost 70 years, fully biodegradable scaffold, virucidal mechanism heparin, spectrum viral inhibitors, irreversible nontoxic broad, nanomolar activity

Relation: https://figshare.com/articles/journal_contribution/Polyanionic_Amphiphilic_Dendritic_Polyglycerols_as_Broad-Spectrum_Viral_Inhibitors_with_a_Virucidal_Mechanism/17912048

الاتاحة: https://doi.org/10.1021/acs.biomac.1c01376.s001

المؤلفون: Makoto Fushimi (1714441), Hannes Buck (11133216), Melanie Balbach (3354395), Anna Gorovyy (11133219), Jacob Ferreira (11133222), Thomas Rossetti (11133225), Navpreet Kaur (3162048), Lonny R. Levin (7818410), Jochen Buck (53581), Jonathan Quast (11133228), Joop van den Heuvel (192614), Clemens Steegborn (117996), Efrat Finkin-Groner (2013025), Stacia Kargman (1436677), Mayako Michino (1533277), Michael A. Foley (1289370), Michael Miller (821), Nigel J. Liverton (1834777), David J. Huggins (243837), Peter T. Meinke (1730713)

مصطلحات موضوعية: Biochemistry, Microbiology, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Cancer, Hematology, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, TDI -10229, exhibits mouse pharmacokinetic prop., sAC inhibitors, displays nanomolar inhibition, sAC inhibition, vivo tool compound, Orally Bioavailable Inhibitor, vivo interrogation, ADCY, Soluble Adenylyl Cyclase

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_TDI-10229_A_Potent_and_Orally_Bioavailable_Inhibitor_of_Soluble_Adenylyl_Cyclase_sAC_ADCY10_/14981295

الاتاحة: https://doi.org/10.1021/acsmedchemlett.1c00273.s001

المؤلفون: Brendan J. Byatt (10730526), Atsushi Kato (264067), Stephen G. Pyne (1403101)

مصطلحات موضوعية: Biochemistry, Medicine, Neuroscience, Pharmacology, Ecology, Marine Biology, Space Science, Chemical Sciences not elsewhere classified, nanomolar inhibition, liver β- glucosidase, Structural Revision, piperidine, product 1- deoxynojirimycin, β- galactosidase, iminosugar core, glyphaeaside C, Synthesi, nature, l-DMDP-derived configuration, DNJ, kind, dideoxy, enantiomer, synthesis

Relation: https://figshare.com/articles/journal_contribution/Synthesis_and_Structural_Revision_of_Glyphaeaside_C/14519211

الاتاحة: https://doi.org/10.1021/acs.orglett.1c01248.s002

المؤلفون: Krasavin M., Shetnev A., Sharonova T., Baykov S., Tuccinardi T., Kalinin S., Angeli A., Supuran C.T.

المصدر: Bioorganic Chemistry

مصطلحات موضوعية: 1,2,4-Oxadiazole, Acylation, Carbonic anhydrase, Cyclodehydration, Isoform-selective inhibitors, Nanomolar inhibition, Periphery groups, Primary sulfonamides, Superbase

Relation: https://doi.org/10.1016/j.bioorg.2017.10.005; https://openrepository.ru/article?id=257720

الاتاحة: https://openrepository.ru/article?id=257720

المؤلفون: Nocentini, Alessio, Moi, Davide, Balboni, Gianfranco, Salvadori, Severo, Onnis, Valentina, Supuran, Claudiu T.

المساهمون: Nocentini, Alessio, Moi, Davide, Balboni, Gianfranco, Salvadori, Severo, Onnis, Valentina, Supuran, Claudiu T.

مصطلحات موضوعية: Carbonic anhydrase, Zinc-binding group, Aromatic sulfamate, Celecoxib, Sulfamoylation, Sub-nanomolar inhibition

Relation: info:eu-repo/semantics/altIdentifier/pmid/29502024; info:eu-repo/semantics/altIdentifier/wos/WOS:000428013300068; volume:77; firstpage:633; lastpage:639; numberofpages:7; journal:BIOORGANIC CHEMISTRY; http://hdl.handle.net/11584/239103; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85042698659; https://www.sciencedirect.com/science/article/pii/S0045206818300518?via=ihub

الاتاحة: http://hdl.handle.net/11584/239103
https://doi.org/10.1016/j.bioorg.2018.02.021
https://www.sciencedirect.com/science/article/pii/S0045206818300518?via=ihub

المؤلفون: Mikhail Krasavin, Claudiu T. Supuran, Andrea Angeli, Stanislav Kalinin, Anton Shetnev, Sergey V. Baykov, Tiziano Tuccinardi, Tatyana Sharonova

المصدر: Bioorganic Chemistry. 76:88-97

مصطلحات موضوعية: Gene isoform, Nanomolar inhibition, Membrane bound, Stereochemistry, Acylation, Carbonic Anhydrase II, 01 natural sciences, Biochemistry, Periphery groups, Structure-Activity Relationship, Antigens, Neoplasm, Cyclodehydration, Carbonic anhydrase, Drug Discovery, Superbase, Humans, Carbonic Anhydrase IX, Carbonic Anhydrase Inhibitors, Isoform-selective inhibitors, Molecular Biology, Cellular localization, Enzyme Assays, chemistry.chemical_classification, Oxadiazoles, Sulfonamides, Binding Sites, Molecular Structure, 4-Oxadiazole, biology, 010405 organic chemistry, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, 0104 chemical sciences, Molecular Docking Simulation, 1,2,4-Oxadiazole, Primary sulfonamides, 010404 medicinal & biomolecular chemistry, Cytosol, Enzyme, chemistry, Docking (molecular), Drug Design, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740443a84c911f3a342531c92cad9e85
https://doi.org/10.1016/j.bioorg.2017.10.005

المؤلفون: Nocentini, Alessio, Moi, Davide, Balboni, Gianfranco, Onnis, Valentina, Supuran, Claudiu T.

المساهمون: Nocentini, Alessio, Moi, Davide, Balboni, Gianfranco, Onnis, Valentina, Supuran, Claudiu T.

مصطلحات موضوعية: Carbonic anhydrase, Zinc-binding group, Aromatic sulfamate, Phenol, Sulfamoylation, Nanomolar inhibition

Relation: info:eu-repo/semantics/altIdentifier/pmid/29421705; info:eu-repo/semantics/altIdentifier/wos/WOS:000428013300031; volume:77; firstpage:293; lastpage:299; numberofpages:7; journal:BIOORGANIC CHEMISTRY; http://hdl.handle.net/11584/236366; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85041663048; https://www.sciencedirect.com/science/article/pii/S0045206817308921?via=ihub

الاتاحة: http://hdl.handle.net/11584/236366
https://doi.org/10.1016/j.bioorg.2018.01.023
https://www.sciencedirect.com/science/article/pii/S0045206817308921?via=ihub

المؤلفون: Fang Li, Zhixiang Zhao, Wei Chen, Ruiyuan Liu, Huizhe Lu, Yanhong Dong, Qing Yang, Jianjun Zhang

مصطلحات موضوعية: Biochemistry, Microbiology, Neuroscience, Pharmacology, Biotechnology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, toxicity studies indicated, lepidoptera plutella xylostella, exhibited negligible toxicity, achieved nanomolar inhibition, 76 μm ), 3 nm ), showed high mortality, novel chitinase inhibitors, novel carbamoylguanidinyl nitrobenzoxadiazoles, chitinolytic enzymes chitinase, 8d , 50 , chitinolytic enzymes, mortality rate, innovative inhibitors, n <, similar modes, results indicate, promising candidate, new angle, important target

Relation: https://figshare.com/articles/journal_contribution/Design_Synthesis_and_Biological_Investigations_of_Novel_Carbamoylguanidinyl_Nitrobenzoxadiazoles_against_Chitinolytic_Enzymes/24570481

الاتاحة: https://doi.org/10.1021/acs.jafc.3c06157.s001
https://figshare.com/articles/journal_contribution/Design_Synthesis_and_Biological_Investigations_of_Novel_Carbamoylguanidinyl_Nitrobenzoxadiazoles_against_Chitinolytic_Enzymes/24570481

المؤلفون: Krasavin M., Shetnev A., Sharonova T., Baykov S., Tuccinardi T., Kalinin S., Angeli A., Supuran C.T.

المصدر: Bioorganic Chemistry

مصطلحات موضوعية: 1,2,4-Oxadiazole, Acylation, Carbonic anhydrase, Cyclodehydration, Isoform-selective inhibitors, Nanomolar inhibition, Periphery groups, Primary sulfonamides, Superbase

Relation: https://doi.org/10.1016/j.bioorg.2017.10.005; https://repository.rudn.ru/records/article/record/6881/

الاتاحة: https://repository.rudn.ru/records/article/record/6881/

المؤلفون: Krasavin M., Shetnev A., Sharonova T., Baykov S., Tuccinardi T., Kalinin S., Angeli A., Supuran C.T.

المصدر: Bioorganic Chemistry

مصطلحات الفهرس: 1,2,4-Oxadiazole, Acylation, Carbonic anhydrase, Cyclodehydration, Isoform-selective inhibitors, Nanomolar inhibition, Periphery groups, Primary sulfonamides, Superbase, Article

URL: http://hdl.handle.net/rour/257720uri
https://doi.org/10.1016/j.bioorg.2017.10.005
https://doi.org/10.1016/j.bioorg.2017.10.005