يعرض 1 - 20 نتائج من 38 نتيجة بحث عن '"Nakia D. Spencer"', وقت الاستعلام: 0.44s تنقيح النتائج
  1. 1
    Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Abdullah A. Osman, Emre Arslan, Mason Bartels, Chieko Michikawa, Antje Lindemann, Katarzyna Tomczak, Wangjie Yu, Vlad Sandulache, Wencai Ma, Li Shen, Jing Wang, Anand K. Singh, Mitchell J. Frederick, Nakia D. Spencer, Jeffery Kovacs, Timothy Heffernan, William F. Symmans, Kunal Rai, Jeffrey N. Myers

    المصدر: Clinical Cancer Research. 29:1344-1359

    مصطلحات موضوعية: Cancer Research, Oncology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::65479fd9a28a8b20c57e1f729431b22f
    https://doi.org/10.1158/1078-0432.ccr-22-2747

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  2. 2
    Supplementary Table S4 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d3823b4690e44d051665650eb8d994e
    https://doi.org/10.1158/1078-0432.22494741

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  3. 3
    Supplementary Table S1 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bd115b418deeae1124f97131e6285c2
    https://doi.org/10.1158/1078-0432.22494750

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  4. 4
    Supplementary Table S3 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79654d612704a9000b36c80a6975e371
    https://doi.org/10.1158/1078-0432.22494744

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  5. 5
    Supplementary Figure S7 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2c39503ad676647284b8b533ed237f
    https://doi.org/10.1158/1078-0432.22494765.v1

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  6. 6
    Data from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c04850927811f29801f3067657f18d
    https://doi.org/10.1158/1078-0432.c.6533191.v2

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  7. 7
    Supplementary Figure S5 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa46891bb8afb255351d168d91677212
    https://doi.org/10.1158/1078-0432.22494771.v1

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  8. 8
    Supplementary Figure S2 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99cf304a227edc1df9fe75ca6ccd9807
    https://doi.org/10.1158/1078-0432.22494783

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  9. 9
    Supplementary Figure S1 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0233a996c9061b4c3f2183dd27ae519c
    https://doi.org/10.1158/1078-0432.22494786.v1

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  10. 10
    Supplementary Table S2 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f267c848bd76d0224f1bc3d9c94f78
    https://doi.org/10.1158/1078-0432.22494747

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  11. 11
    Supplementary Table S5 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2efad91a3b1abda46cff49750c31a38a
    https://doi.org/10.1158/1078-0432.22494738

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  12. 12
    Supplementary Figure S8 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35147c851f739793c5ff44bb957de5bc
    https://doi.org/10.1158/1078-0432.22490662

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  13. 13
    Supplementary Figure S3 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21e88a851401a229a24d4a4c88a48930
    https://doi.org/10.1158/1078-0432.22490677

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  14. 14
    Supplementary Materials and Methods S1 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78a4d28fe5032cc717680b8ae29d5b5f
    https://doi.org/10.1158/1078-0432.22490656.v1

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  15. 15
    Supplementary Figure S4 from Dysregulation and Epigenetic Reprogramming of NRF2 Signaling Axis Promote Acquisition of Cisplatin Resistance and Metastasis in Head and Neck Squamous Cell Carcinoma

    المؤلفون: Jeffrey N. Myers, Kunal Rai, William F. Symmans, Timothy Heffernan, Jeffery Kovacs, Nakia D. Spencer, Mitchell J. Frederick, Anand K. Singh, Jing Wang, Li Shen, Wencai Ma, Vlad Sandulache, Wangjie Yu, Katarzyna Tomczak, Antje Lindemann, Chieko Michikawa, Mason Bartels, Emre Arslan, Abdullah A. Osman

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f54ded26d769013bafdb5b8add3180d
    https://doi.org/10.1158/1078-0432.22490674

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  16. 16
    Supplementary information from Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

    المؤلفون: Philip Jones, Nancy E. Kohl, Timothy P. Heffernan, Joseph R. Marszalek, Giulio F. Draetta, Andy M. Zuniga, Simon S. Yu, Christopher C. Williams, Erika Suzuki, Nakia D. Spencer, Sahil Seth, Vandhana Ramamoorthy, Michael Peoples, Robert A. Mullinax, Meredith A. Miller, Timothy McAfoos, Pijus K. Mandal, Xiaoyan Ma, Anastasia M. Lopez, Chiu-Yi Liu, Jeffrey J. Kovacs, Zhijun Kang, Yongying Jiang, Justin K. Huang, Virginia Giuliani, Sonal Gera, Guang Gao, Ningping Feng, Qing Chang, Christopher L. Carroll, Caroline C. Carrillo, Jason P. Burke, Christopher A. Bristow, Benjamin J. Bivona, Maria Emilia Di Francesco, Jason B. Cross, Connor A. Parker, Sarah Johnson, Qi Wu, Angela L. Harris, Faika Mseeh, Paul Leonard, Barbara Czako, Brooke A. Meyers, Yuting Sun

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb5082d82bd02f09e6060ee7ba89279
    https://doi.org/10.1158/0008-5472.22425706.v1

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  17. 17
    Data from Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

    المؤلفون: Philip Jones, Nancy E. Kohl, Timothy P. Heffernan, Joseph R. Marszalek, Giulio F. Draetta, Andy M. Zuniga, Simon S. Yu, Christopher C. Williams, Erika Suzuki, Nakia D. Spencer, Sahil Seth, Vandhana Ramamoorthy, Michael Peoples, Robert A. Mullinax, Meredith A. Miller, Timothy McAfoos, Pijus K. Mandal, Xiaoyan Ma, Anastasia M. Lopez, Chiu-Yi Liu, Jeffrey J. Kovacs, Zhijun Kang, Yongying Jiang, Justin K. Huang, Virginia Giuliani, Sonal Gera, Guang Gao, Ningping Feng, Qing Chang, Christopher L. Carroll, Caroline C. Carrillo, Jason P. Burke, Christopher A. Bristow, Benjamin J. Bivona, Maria Emilia Di Francesco, Jason B. Cross, Connor A. Parker, Sarah Johnson, Qi Wu, Angela L. Harris, Faika Mseeh, Paul Leonard, Barbara Czako, Brooke A. Meyers, Yuting Sun

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679aa5c2787960118aa25b0d20d0a771
    https://doi.org/10.1158/0008-5472.c.6512119.v1

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  18. 18
    Discovery of IACS-9439, a Potent, Exquisitely Selective, and Orally Bioavailable Inhibitor of CSF1R

    المؤلفون: Timothy P. Heffernan, Angela L. Harris, Martin R. Tremblay, Connor A. Parker, Yongying Jiang, Robert A. Mullinax, Cross Jason, Jihai Pang, Qi Wu, Edward Q. Chang, Sonal Gera, Keith M. Wilcoxen, Paul G. Leonard, Zhen Liu, Jeffrey J. Kovacs, Erika Suzuki, Barbara Czako, Ningping Feng, Joseph R. Marszalek, Nakia D. Spencer, Pijus K. Mandal, Jason P Burke, Simon S. Yu, Keith Mikule, Faika Mseeh, Philip Jones, Giulio Draetta

    المصدر: Journal of Medicinal Chemistry. 63:9888-9911

    مصطلحات موضوعية: Molecular Structure, THP-1 Cells, Chemistry, Macrophage polarization, Antineoplastic Agents, Phenotype, Structure-Activity Relationship, Pyrimidines, Drug Stability, Receptors, Granulocyte-Macrophage Colony-Stimulating Factor, Neoplasms, Tumor-Associated Macrophages, Drug Discovery, Microsomes, Liver, Cancer research, Humans, Molecular Medicine, Structure–activity relationship, THP1 cell line, Benzothiazoles, Kinase activity, Signal transduction, Receptor, Function (biology)

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477eb096ec2e1d0be3af1800c7acd0a9
    https://doi.org/10.1021/acs.jmedchem.0c00936

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  19. 19
    Multi-disciplinary efforts to evaluate the therapeutic potential of CDK11, a novel transcription associated cyclin dependent kinase

    المؤلفون: Christopher L. Carroll, Jan Reiling, Jeffrey Kovacs, Michael Bradley, Meng He, Nadima Uprety, Michael Peoples, Fredierick Robinson, Alessandro Carugo, Michael Conner, Christian Rodriguez, Jennifer Bardenhagen, Vijayan Ramaswamy, Paul Leonard, Zhijun Kang, Catalina Suarez, Teresa Perry, Jing Han, Sonal Fnu, Nakia D. Spencer, Guang Gao, Angela Harris, Alan Xu, Jennifer Linares, Thomas M. Quill, Phuong Nguyen, Qi Wu, Stephanie T. Schmidt, Sahil Seth, Christopher A. Bristow, Norma Rogers, Simon S. Yu, Hannah E. Shepard, Robert A. Mullinax, Sabina A. Lorca, Kang Le, Reagan Lucas, Sweta Mahaeshwari, Sarah Joseph, Ningping Feng, Yongying Jiang, Joe Marszalek, Michael Soth, Jason Cross, Mary Geck Do, M. Emilia Di Francesco, Timothy P. Heffernan, Philip Jones

    المصدر: Leading Edge of Cancer Research Symposium: Poster Session.

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f5416c22383be86ad7b8c251ec603fa0
    https://doi.org/10.52519/00046

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  20. 20
    Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties

    المؤلفون: Michael J. Soth, Kang Le, Maria Emilia Di Francesco, Matthew M. Hamilton, Gang Liu, Jason P. Burke, Chris L. Carroll, Jeffrey J. Kovacs, Jennifer P. Bardenhagen, Christopher A. Bristow, Mario Cardozo, Barbara Czako, Elisa de Stanchina, Ningping Feng, Jill R. Garvey, Jason P. Gay, Mary K. Geck Do, Jennifer Greer, Michelle Han, Angela Harris, Zachary Herrera, Sha Huang, Virginia Giuliani, Yongying Jiang, Sarah B. Johnson, Troy A. Johnson, Zhijun Kang, Paul G. Leonard, Zhen Liu, Timothy McAfoos, Meredith Miller, Pietro Morlacchi, Robert A. Mullinax, Wylie S. Palmer, Jihai Pang, Norma Rogers, Charles M. Rudin, Hannah E. Shepard, Nakia D. Spencer, Jay Theroff, Qi Wu, Alan Xu, Ju Anne Yau, Giulio Draetta, Carlo Toniatti, Timothy P. Heffernan, Philip Jones

    المصدر: J Med Chem

    مصطلحات موضوعية: Male, Drug Evaluation, Preclinical, Phases of clinical research, Administration, Oral, Pharmacology, 01 natural sciences, Article, Rats, Sprague-Dawley, 03 medical and health sciences, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Dogs, Pharmacokinetics, Glutaminase, In vivo, Cell Line, Tumor, Microsomes, Drug Discovery, Structure–activity relationship, Animals, Humans, Enzyme Inhibitors, 030304 developmental biology, 0303 health sciences, Chemistry, Target engagement, Triazoles, Recombinant Proteins, 0104 chemical sciences, Rats, Glutamine, 010404 medicinal & biomolecular chemistry, Cell culture, Hepatocytes, Molecular Medicine, Half-Life, Protein Binding

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b9f179f30ccdc7840fbbad768ec366
    https://europepmc.org/articles/PMC9007139/

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