المؤلفون: Nadine Bakkar, Alexander Starr, Benjamin E. Rabichow, Ileana Lorenzini, Zachary T. McEachin, Robert Kraft, Matthew Chaung, Sam Macklin-Isquierdo, Taylor Wingfield, Briggs Carhart, Nathan Zahler, Wen-Hsuan Chang, Gary J. Bassell, Alexandre Betourne, Nicholas Boulis, Samuel V. Alworth, Justin K. Ichida, Paul R. August, Daniela C. Zarnescu, Rita Sattler, Robert Bowser

المصدر: Neurobiology of Disease, Vol 149, Iss , Pp 105228- (2021)

مصطلحات موضوعية: Copper transport, Amyotrophic lateral sclerosis, ATP7A, iPSC derived motor neurons, Intracellular transport, Copper toxicity, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996120305039; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/9e65354b9c964af3a16790973ddace6f

المؤلفون: Jennifer M. Peterson, David J. Wang, Vikram Shettigar, Steve R. Roof, Benjamin D. Canan, Nadine Bakkar, Jonathan Shintaku, Jin-Mo Gu, Sean C. Little, Nivedita M. Ratnam, Priya Londhe, Leina Lu, Christopher E. Gaw, Jennifer M. Petrosino, Sandya Liyanarachchi, Huating Wang, Paul M. L. Janssen, Jonathan P. Davis, Mark T. Ziolo, Sudarshana M. Sharma, Denis C. Guttridge

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/aa724b3e4c7b4ada9b67a708841b1195

المؤلفون: Kateřina Sheardová, Gustavo Sevlever, Victoria David-Dirgo, Marian Hajduch, Patrick Pirrotte, Clara Limbäck-Stokin, Ritin Sharma, Durga Jha, Robert A. Rissman, Lucia Pertierra, Maria Carna, Richard A. G. Smith, Petr Kaňovsky, Nadine Bakkar, Valentina Lacovich, Hana Markova, Mojmir Vinkler, Giancarlo Forte, Jiri Damborsky, Jan Fric, Silvie Belaskova, Krystine Garcia-Mansfield, Hernan Chaves, Eric B. Dammer, Marketa Nezvedova, Ruben Houbrechts, Gorazd B. Stokin, Nicholas T. Seyfried, Robert Bowser, Martin Vyhnalek, Zuzana Nedelska, Stanislav Katina, Kateřina Texlova, Jan Laczó, Isaac G. Onyango, Thijs Vande Vyvere, Dusan Holub, Zdenek Spacil, Jakub Hort

المصدر: Alzheimer´s & Dementia

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Amyloid, Epidemiology, Inflammation, Pathogenesis, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Cerebrospinal fluid, Developmental Neuroscience, aging, Alzheimer's disease, cerebrospinal fluid, choroid plexus, pathology, medicine, Cognitive decline, 030304 developmental biology, 0303 health sciences, business.industry, Health Policy, Inflammasome, medicine.disease, 3. Good health, Astrogliosis, Psychiatry and Mental health, Choroid plexus, sense organs, Neurology (clinical), medicine.symptom, Geriatrics and Gerontology, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0876e506d5055bb9da0913d0998881ad
https://doi.org/10.1002/alz.12970

المؤلفون: Briggs Carhart, Matthew Chaung, Taylor Wingfield, Sam Macklin-Isquierdo, Gary J. Bassell, Alexander Starr, Ileana Lorenzini, Zachary T. McEachin, Daniela C. Zarnescu, Paul R. August, Robert Bowser, Alexandre Betourne, Nadine Bakkar, Robert Kraft, Nicholas M. Boulis, Nathan Zahler, Justin K. Ichida, Samuel V. Alworth, Benjamin E. Rabichow, Wen-Hsuan Chang, Rita Sattler

المصدر: Neurobiology of Disease, Vol 149, Iss, Pp 105228-(2021)

مصطلحات موضوعية: 0301 basic medicine, ATP7A, Induced Pluripotent Stem Cells, Occipital horn syndrome, Biology, lcsh:RC321-571, Animals, Genetically Modified, 03 medical and health sciences, Mice, 0302 clinical medicine, Copper toxicity, C9orf72, medicine, Animals, Homeostasis, Humans, Amyotrophic lateral sclerosis, Motor Neuron Disease, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Cells, Cultured, Dose-Response Relationship, Drug, Neurodegeneration, Genetic Variation, Motor neuron, Copper transport, medicine.disease, iPSC derived motor neurons, Cell biology, Vesicular transport protein, Protein Transport, 030104 developmental biology, medicine.anatomical_structure, Neurology, Animals, Newborn, Copper-Transporting ATPases, Menkes disease, Drosophila, Intracellular transport, 030217 neurology & neurosurgery, Copper, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1b093cb0d40dc3783f16c5e990d7e3b
http://www.sciencedirect.com/science/article/pii/S0969996120305039

المؤلفون: George A. Carlson, Evan Lester, Jacob I. Ayers, Felicia K. Ooi, Stanley B. Prusiner, Robert Bowser, Nadine Bakkar, Amanda L. Woerman, Joshua Wheeler, Roy Parker

مصطلحات موضوعية: Cytosol, Chemistry, mental disorders, RNA splicing, Organelle, medicine, Colocalization, RNA, Corticobasal degeneration, Small nucleolar RNA, medicine.disease, Frontotemporal dementia, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a7ee8482b4bcb3d3c192cddd999c7efd
https://doi.org/10.1101/2021.01.27.428450

المؤلفون: Nadine Bakkar, Kyle Sponaugle, Ileana Lorenzini, Elenee Argentinis, Alix M. B. Lacoste, Philip Ferrante, Rita Sattler, Robert Bowser, Scott Spangler, Tina Kovalik

المصدر: Acta Neuropathologica

مصطلحات موضوعية: 0301 basic medicine, Artificial intelligence, Motor neuron, RNA-binding protein, Gene Expression, Disease, Biology, Protein Aggregation, Pathological, Genome, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Cerebellum, medicine, Data Mining, Humans, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Retrospective Studies, Original Paper, business.industry, Amyotrophic Lateral Sclerosis, Computational Biology, RNA-Binding Proteins, RNA, medicine.disease, Scholarly Communication, 3. Good health, 030104 developmental biology, Spinal Cord, Human genome, Neurology (clinical), Protein aggregation, business, Ibm watson, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2232f10a1355c82fa12ede82b4c79371
https://doi.org/10.1007/s00401-017-1785-8

المؤلفون: Nadine Bakkar, Jacob I. Ayers, Evan Lester, George A. Carlson, Stanley B. Prusiner, Felicia K. Ooi, Roy Parker, Robert Bowser, Amanda L. Woerman, Joshua Wheeler

المصدر: Neuron

مصطلحات موضوعية: Male, 0301 basic medicine, RNA Splicing, tau Proteins, RNA-binding protein, Article, Mice, 03 medical and health sciences, Cytosol, 0302 clinical medicine, Alzheimer Disease, mental disorders, Organelle, medicine, Animals, Humans, RNA, Small Nucleolar, Corticobasal degeneration, Small nucleolar RNA, Neurons, Cell Nucleus, Chemistry, General Neuroscience, RNA-Binding Proteins, RNA, Neurodegenerative Diseases, medicine.disease, Cell biology, Mice, Inbred C57BL, Protein Transport, HEK293 Cells, 030104 developmental biology, Tauopathies, RNA splicing, Female, 030217 neurology & neurosurgery, Small nuclear RNA, Protein Binding, Frontotemporal dementia

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a228d7dd536c180f83ad5c907139f5ca
https://doi.org/10.1016/j.neuron.2021.03.026

المؤلفون: Robert Bowser, Ashley Boehringer, Nadine Bakkar

المصدر: Brain Research. 1607:94-107

مصطلحات موضوعية: Oncology, Drug, medicine.medical_specialty, media_common.quotation_subject, Pharmacology, Article, Internal medicine, Drug Discovery, medicine, Animals, Humans, Biomarker discovery, Amyotrophic lateral sclerosis, Molecular Biology, media_common, Clinical Trials as Topic, Drug discovery, business.industry, General Neuroscience, Amyotrophic Lateral Sclerosis, Disease progression, Prognosis, medicine.disease, Clinical trial, Clinical research, Drug development, Neurology (clinical), business, Biomarkers, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72de5d45350de834de7e212cbf762e70
https://doi.org/10.1016/j.brainres.2014.10.031

المؤلفون: Patrick Pirrotte, Robert Bowser, Nadine Bakkar, Krystine Garcia-Mansfield, Ashley Boehringer, Gurkaran Singh

المصدر: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)

مصطلحات موضوعية: 0301 basic medicine, Immunoprecipitation, Mutant, Active Transport, Cell Nucleus, lcsh:Medicine, RNA-binding protein, Biology, Interactome, Article, Mass Spectrometry, 03 medical and health sciences, 0302 clinical medicine, Nuclear Matrix-Associated Proteins, Transcription (biology), MRNA transport, Humans, Protein Interaction Maps, RNA, Messenger, lcsh:Science, Nuclear export signal, Messenger RNA, Multidisciplinary, lcsh:R, Amyotrophic Lateral Sclerosis, RNA-Binding Proteins, Cell biology, 030104 developmental biology, Mutation, lcsh:Q, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461d8b386bde8de60252f3d1d22a132d
http://europepmc.org/articles/PMC5674072

المؤلفون: Muthu Periasamy, Paul M.L. Janssen, Denis C. Guttridge, Nadine Bakkar, Katherine J. Ladner, Qiutang Li, Sandya Liyanarachchi, Benjamin D. Canan, Naresh C. Bal, Meghna Pant

المصدر: Journal of Cell Biology. 196:497-511

مصطلحات موضوعية: 0303 health sciences, Myogenesis, RELB, Skeletal muscle, Cell Biology, IκB kinase, Biology, 3. Good health, Cell biology, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Mitochondrial biogenesis, Biochemistry, Alternative complement pathway, medicine, Signal transduction, 030217 neurology & neurosurgery, PI3K/AKT/mTOR pathway, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::851e10ea6bbc2719c682e2e498099fea
https://doi.org/10.1083/jcb.201108118

المؤلفون: Nadine Bakkar, Denis C. Guttridge

المصدر: Physiological Reviews. 90:495-511

مصطلحات موضوعية: Physiology, Myogenesis, RELB, NF-kappa B, Skeletal muscle, General Medicine, Biology, Muscle disorder, Muscle Development, Cell biology, Skeletal muscle cell differentiation, medicine.anatomical_structure, Muscular Diseases, Mitochondrial biogenesis, Physiology (medical), medicine, Animals, Myocyte, Muscle, Skeletal, Molecular Biology, Transcription factor, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892abc7fed16f3fbf310ceb86ca598cc
https://doi.org/10.1152/physrev.00040.2009

المؤلفون: Jason M. Dahlman, Dennis C. Guttridge, Nadine Bakkar, Wei He

المصدر: Journal of Biological Chemistry. 285:5479-5487

مصطلحات موضوعية: medicine.medical_specialty, Myoblasts, Skeletal, Cellular differentiation, Nitric Oxide Synthase Type II, Biology, Muscle Development, Biochemistry, Gene Expression Regulation, Enzymologic, Muscle hypertrophy, Mice, chemistry.chemical_compound, Myoblast fusion, Internal medicine, medicine, Animals, Myocyte, Muscle, Skeletal, Molecular Biology, Psychological repression, Mice, Knockout, Myogenesis, Transcription Factor RelA, Skeletal muscle, NF-κB, Cell Biology, Fibroblasts, I-kappa B Kinase, Endocrinology, medicine.anatomical_structure, chemistry, I-kappa B Proteins, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93899e8920901c0305a3586bc270af17
https://doi.org/10.1074/jbc.m109.075606

المؤلفون: Nadine Bakkar, Denis C. Guttridge, Jason M. Dahlman, Jingxin Wang

المصدر: Journal of Cellular Biochemistry. 106:42-51

مصطلحات موضوعية: Cyclin D, Cyclin A, Cyclin B, Mice, Transgenic, Muscle Development, Biochemistry, Myoblasts, Mice, Cyclin D1, Cyclin-dependent kinase, Animals, RNA, Messenger, Muscle, Skeletal, Molecular Biology, Cells, Cultured, RELA, biology, Protein Stability, Cell Cycle, Transcription Factor RelA, Cell Differentiation, Cell Biology, Fibroblasts, Cell biology, Protein Subunits, biology.protein, Cancer research, Cyclin-dependent kinase complex, Cyclin A2

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c11f80e86bea656cbc2cefbbaeee1a46
https://doi.org/10.1002/jcb.21976

المؤلفون: Nadine Bakkar, Jason M. Dahlman, Katherine J. Ladner, Andrew D. Hollenbach, Huating Wang, Jingxin Wang, Micheal Carathers, Denis C. Guttridge, Swarnali Acharyya, Michael A. Rudnicki

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: Myoblasts, Skeletal, Cellular differentiation, Muscle Fibers, Skeletal, Transcription Factor RelA, Down-Regulation, Mice, Transgenic, IκB kinase, Biology, Mitochondrion, Muscle Development, Article, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Animals, Muscle, Skeletal, Cells, Cultured, Research Articles, 030304 developmental biology, Genetics, 0303 health sciences, Myogenesis, RELB, NF-kappa B, Gene Expression Regulation, Developmental, Correction, Cell Differentiation, Cell Biology, I-kappa B Kinase, Mitochondria, Cell biology, Animals, Newborn, Mitochondrial biogenesis, 030220 oncology & carcinogenesis, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f72ba847fe83703166f89c96da76f5f0
https://doi.org/10.1083/jcb.200707179

المؤلفون: Sankar Ghosh, Zhi-Wei Li, James G. Tidball, Michael Weinstein, Katherine L. Gardner, Nadine Bakkar, Albert S. Baldwin, Micheal Carathers, Amer A. Beg, Jill A. Rafael-Fortney, Denis C. Guttridge, Swarnali Acharyya, S. Armando Villalta, Michael Karin, Paul M.L. Janssen, Zarife Sahenk, Tepmanas Bupha-Intr

المصدر: Journal of Clinical Investigation. 117:889-901

مصطلحات موضوعية: musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, Duchenne muscular dystrophy, Muscle Fibers, Skeletal, Inflammation, IκB kinase, Biology, Mice, medicine, Animals, Humans, Muscular dystrophy, Muscle, Skeletal, Mice, Knockout, Macrophages, NF-kappa B, Transcription Factor RelA, Skeletal muscle, General Medicine, medicine.disease, NFKB1, I-kappa B Kinase, Muscular Dystrophy, Duchenne, Disease Models, Animal, medicine.anatomical_structure, Disease Progression, Cancer research, biology.protein, medicine.symptom, ITGA7, Dystrophin, Gene Deletion, Signal Transduction, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::347d34f66063f276aadf19389c00481e
https://doi.org/10.1172/jci30556

المؤلفون: Arianna Kousari, Nadine Bakkar, Yang Li, Robert Bowser, Tina Kovalik

مصطلحات موضوعية: Adult, Male, Immunoblotting, Gene Expression, RNA-binding protein, Nerve Tissue Proteins, Oxidative phosphorylation, Biology, medicine.disease_cause, Neuroprotection, Antioxidants, Rats, Sprague-Dawley, Cell Line, Tumor, medicine, Animals, Humans, Amyotrophic lateral sclerosis, Molecular Biology, Transcription factor, Cells, Cultured, Aged, Aged, 80 and over, Kelch-Like ECH-Associated Protein 1, Reverse Transcriptase Polymerase Chain Reaction, Amyotrophic Lateral Sclerosis, Intracellular Signaling Peptides and Proteins, RNA-Binding Proteins, Cell Biology, Articles, Middle Aged, medicine.disease, Spinal cord, KEAP1, Cell biology, medicine.anatomical_structure, HEK293 Cells, Microscopy, Fluorescence, Spinal Cord, Immunology, Female, RNA Interference, Oxidative stress, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0c0a2f365f6352335e6f8ac0dcc4d5e
https://europepmc.org/articles/PMC4475920/

المؤلفون: Yang Li, Mahlon Collins, Robert Bowser, David Riascos, Nadine Bakkar, Rachel Geiser

المصدر: Scientific Reports

مصطلحات موضوعية: Molecular Sequence Data, Nuclear Localization Signals, Active Transport, Cell Nucleus, RNA-binding protein, Nerve Tissue Proteins, Plasma protein binding, Biology, DNA-binding protein, Protein Aggregation, Pathological, Inclusion bodies, Article, Cell Line, Stress granule, mental disorders, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, Protein Interaction Maps, Peptide sequence, Genetics, Inclusion Bodies, Multidisciplinary, RNA-Binding Proteins, Cell biology, Transport protein, DNA-Binding Proteins, Protein Transport, Mutation, RNA-Binding Protein FUS, Protein Multimerization, Carrier Proteins, Sequence Alignment, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce0886cbe2d23a010d456bb0372c055f
https://pubmed.ncbi.nlm.nih.gov/26391765

المؤلفون: Nadine Bakkar, Denis C. Guttridge, Henning Wackerhage

المصدر: Signal Transduction. 5:202-210

مصطلحات موضوعية: Myoblast proliferation, Myogenesis, Skeletal muscle, Cell Biology, Myostatin, Biology, MyoD, medicine.anatomical_structure, Cancer research, medicine, biology.protein, Myocyte, Molecular Biology, C2C12, Myogenin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::05fea4b31ecef88eb62808fc5dff3a07
https://doi.org/10.1002/sita.200400039

المؤلفون: Jingxin Wang, Denis C. Guttridge, Erin Hertlein, Nadine Bakkar, Katherine J. Ladner

المصدر: Molecular and Cellular Biology. 25:4956-4968

مصطلحات موضوعية: IκBα, Proteasome, Protein subunit, Transcription Factor RelA, Phosphorylation, Cellular homeostasis, Cell Biology, Biology, NFKB1, Molecular Biology, DNA-binding protein, Molecular biology, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5e6dd5891d7c38c290c78d855c831792
https://doi.org/10.1128/mcb.25.12.4956-4968.2005

المؤلفون: Nadine Bakkar, Suzanne Werner, Carl E. Stafstrom, Lionel Carmant, Gregory L. Holmes, Mohamad A. Mikati, Zhao Liu

المصدر: Epilepsy & Behavior. 5:168-174

مصطلحات موضوعية: Male, medicine.drug_class, Premedication, Morris water navigation task, Status epilepticus, Calcium channel blocker, Motor Activity, Pharmacology, Open field, Rats, Sprague-Dawley, Behavioral Neuroscience, Epilepsy, Status Epilepticus, Memory, medicine, Animals, Maze Learning, Nimodipine, Behavior, Animal, business.industry, Calcium channel, Calcium Channel Blockers, medicine.disease, Rats, Aggression, Neurology, Phenobarbital, Anesthesia, Anticonvulsants, Drug Therapy, Combination, Female, Neurology (clinical), medicine.symptom, business, Injections, Intraperitoneal, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebda70e450b3083b4cbd0071461c1988
https://doi.org/10.1016/j.yebeh.2003.12.002