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1Academic JournalCrystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase
المؤلفون: Huiying Li, Christine D. Hardy, Cory T. Reidl, Qing Jing, Fengtian Xue, Maris Cinelli, Richard B. Silverman, Thomas L. Poulos
مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Neuroscience, Physiology, Pharmacology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, nitric oxide synthase, undergo conformational changes, substantial dynamic differences, computational results show, second inhibitor molecule, tighter dimer interface, conserved tyrosine near, subtle structural differences, develop inhibitors selective, nos inhibitor binding, dimer interface, conserved tyrosine, selective inhibitors, structural basis, nos isoforms, changes conformation, selective dynamics, computational methods, computational insights, inhibitor binding
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2Academic Journal
المؤلفون: Marina Filimonova, Anna Shitova, Ljudmila Shevchenko, Olga Soldatova, Valentina Surinova, Vitaly Rybachuk, Alexander Kosachenko, Kirill Nikolaev, Irina Volkova, Grigory Demyashkin, Tatjana P. Stanojkovic, Zeljko Zizak, Sergey Ivanov, Petr Shegay, Andrey Kaprin, Alexander Filimonov
المصدر: International Journal of Molecular Sciences, Vol 25, Iss 17, p 9711 (2024)
مصطلحات موضوعية: NOS-inhibitor, PDK-inhibitor, cytotoxic effect, antitumor effect, hypoxic resistance, cervical cancer, Biology (General), QH301-705.5, Chemistry, QD1-999
Relation: https://www.mdpi.com/1422-0067/25/17/9711; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/4eca73e7d3b34cacaa20c671b903a0f4
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3Academic Journal
المؤلفون: Roman Roy, Joshua Wilcox, Andrew J. Webb, Kevin O’Gallagher
المصدر: International Journal of Molecular Sciences, Vol 24, Iss 15200, p 15200 (2023)
مصطلحات موضوعية: nitric oxide synthase, endothelial NOS, neuronal NOS, inducible NOS, NOS inhibitor, cardiovascular disease, Biology (General), QH301-705.5, Chemistry, QD1-999
Relation: https://www.mdpi.com/1422-0067/24/20/15200; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/3673b65fd0014c47ae7baad729d94073
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4Academic Journal
المؤلفون: Marina Filimonova, Ljudmila Shevchenko, Victoria Makarchuk, Alina Saburova, Petr Shegay, Andrey Kaprin, Sergey Ivanov, Alexander Filimonov
المصدر: Frontiers in Pharmacology, Vol 13 (2022)
مصطلحات موضوعية: hemorrhagic shock, in vivo models, vasopressor activity, NOS inhibitor, rats, dogs, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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5Academic Journal
المؤلفون: Marina Filimonova, Anna Shitova, Olga Soldatova, Ljudmila Shevchenko, Alina Saburova, Tatjana Podosinnikova, Valentina Surinova, Petr Shegay, Andrey Kaprin, Sergey Ivanov, Alexander Filimonov
المصدر: International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 730
مصطلحات موضوعية: NOS-inhibitor, PDK-inhibitor, antitumor effect, hypoxic resistance, Erlich carcinoma
جغرافية الموضوع: agris
وصف الملف: application/pdf
Relation: Molecular Oncology; https://dx.doi.org/10.3390/ijms23020730
الاتاحة: https://doi.org/10.3390/ijms23020730
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6Academic Journal
المصدر: Joca , S , Sartim , A , Roncalho , A , Diniz , C & Wegener , G 2019 , ' Nitric oxide signalling and antidepressant action revisited ' , Cell and Tissue Research , vol. 377 , no. 1 , pp. 45-58 . https://doi.org/10.1007/s00441-018-02987-4
مصطلحات موضوعية: Antidepressants, BDNF, Depression, Neuroplasticity, Nitric oxide, METHYLENE-BLUE, NEUROTROPHIC FACTOR, NEURONAL NOS INHIBITOR, FORCED SWIMMING TEST, SOLUBLE GUANYLATE-CYCLASE, SEROTONIN REUPTAKE INHIBITORS, SENSITIVE LINE RATS, SMALL-MOLECULE INHIBITORS, MAJOR DEPRESSIVE DISORDER, PITUITARY-ADRENAL AXIS, Neurotransmitter Agents/pharmacology, Humans, Nitric Oxide/metabolism, Mood Disorders/drug therapy, Brain/drug effects, Signal Transduction, Rats, Antidepressive Agents/pharmacology, Brain-Derived Neurotrophic Factor/metabolism, Animals, Neuronal Plasticity, Mice
وصف الملف: application/pdf
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7
المؤلفون: M. V. Filimonova, A. S. Saburova, L. I. Shevchenko, V. M. Makarchuk, A. A. Lychagin, A. S. Filimonov
المصدر: Radiacionnaâ Gigiena, Vol 14, Iss 1, Pp 68-74 (2021)
مصطلحات موضوعية: 0301 basic medicine, NOS inhibitor, Radioprotective Agent, R895-920, Spleen, Endogeny, acute toxicity, Pharmacology, Chemical synthesis, Medical physics. Medical radiology. Nuclear medicine, 03 medical and health sciences, 0302 clinical medicine, no synthase inhibitors, medicine, hematopoietic splenic colonies, Radiology, Nuclear Medicine and imaging, QC794.95-798, Radioactivity and radioactive substances, Chemistry, Acute toxicity, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Toxicity, radioprotective efficacy
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8Academic Journal
المؤلفون: Kıroğlu, Olcay Gürhan, Yorulmaz Özü, Özlem, Emre, Mustafa, Bayel, İhsan, Karabal Kumcu, Eda, Seçilmiş, M. Ata
المساهمون: Çukurova Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, orcid.org/0000-0003-3182-2122, Kıroğlu, Olcay Gürhan, Yorulmaz Özü, Özlem, Emre, Mustafa, Bayel, İhsan, Karabal Kumcu, Eda, Seçilmiş, M. Ata
مصطلحات موضوعية: Isometric contraction, Membrane potential, Mesenteric artery, NOS inhibitor-insensitive residual NO
وصف الملف: application/pdf
Relation: Nitric Oxide; Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı; Kıroğlu, O. E., Özü, Ö. Y., Emre, M., Bayel, İ., Kumcu, E. K., & Seçilmiş, M. A. (2017). Residual NO modulates contractile responses and membrane potential in isolated rat mesenteric arteries. Nitric Oxide, 71, 21-26.; https://hdl.handle.net/20.500.12605/35808; 71; 21; 26
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9
المؤلفون: A. S. Saburova, M. V. Filimonova, V. V. Yuzhakov, L. I. Shevchenko, N. D. Yakovleva, L. N. Bandurko, A. E. Koretskaya, N. K. Fomina, V. O. Saburov, A. S. Filimonov
المصدر: Radiacionnaâ Gigiena, Vol 13, Iss 1, Pp 60-67 (2020)
مصطلحات موضوعية: Pathology, medicine.medical_specialty, NOS inhibitor, medicine.medical_treatment, R895-920, Connective tissue, Radiation induced, 030204 cardiovascular system & hematology, 03 medical and health sciences, Medical physics. Medical radiology. Nuclear medicine, 0302 clinical medicine, Parenchyma, no synthase inhibitors, medicine, Radiology, Nuclear Medicine and imaging, Irradiation, QC794.95-798, Radioactivity and radioactive substances, Lung, radiation pneumofibrosi, business.industry, radioprotective effects, Radiation therapy, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Radiation reaction, business, late radiation injuries
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10Book
المؤلفون: Dao, Vu Thao Vi, Elbatreek, Mahmoud H., Fuchß, Thomas, Grädler, Ulrich, Schmidt, Harald H.H.W., Shah, Ajay M., Wallace, Alan, Knowles, Richard
المصدر: Dao , V T V , Elbatreek , M H , Fuchß , T , Grädler , U , Schmidt , H H H W , Shah , A M , Wallace , A & Knowles , R 2021 , Nitric Oxide Synthase Inhibitors into the Clinic at Last . in Handbook of Experimental Pharmacology . Handbook of Experimental Pharmacology , vol. 264 , Springer Science and Business Media Deutschland GmbH , pp. 169-204 . https://doi.org/10.1007/164_2020_382
مصطلحات موضوعية: Nitric oxide, Nitric oxide synthase, NOS, NOS inhibitor, NOS isoforms
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11Academic Journal
المساهمون: Demir, Suleyman, Bulut, Mahmut, Atli, Abdullah, Kaplan, Ibrahim, Kaya, Mehmet Cemal, Bez, Yasin, Ozdemir, Pinar Guzel, Sir, Aytekin
مصطلحات موضوعية: PTSD, Prolidase activity, Neuroprotective, NOS INHIBITOR 1-(2-TRIFLUOROMETHYLPHENYL)-IMIDAZOLE, FORCED SWIMMING TEST, NITRIC-OXIDE, OXIDATIVE-STRESS, EARTHQUAKE SURVIVORS, EXTRACELLULAR-MATRIX, ANTIDEPRESSANT-LIKE, NATURAL DISASTER, NMDA RECEPTOR, MENTAL-HEALTH
وصف الملف: application/pdf
Relation: PSYCHIATRY INVESTIGATION; https://hdl.handle.net/11424/241457; WOS:000380733300007
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12Academic Journal
المصدر: Acta Medica Iranica, Vol 45, Iss 5, Pp 329-338 (2007)
مصطلحات موضوعية: NOS inhibitor, mouse oocyte maturation, Medicine (General), R5-920
وصف الملف: electronic resource
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13Academic Journal
المصدر: Frontiers in Neurology, Vol 6 (2015)
مصطلحات موضوعية: Corpus Callosum, Stroke, Vasoconstriction, Mouse, Lysophosphatidylcholine, NOS inhibitor, Neurology. Diseases of the nervous system, RC346-429
وصف الملف: electronic resource
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14
المؤلفون: Makarchuk Vm, O.S. Izmestieva, A.S. Saburova, M.V. Filimonova, Shevchenko Li, A.S. Filimonov
المصدر: "Radiation and Risk" Bulletin of the National Radiation and Epidemiological Registry. 29:45-56
مصطلحات موضوعية: Nuclear and High Energy Physics, NOS inhibitor, Radiation, Chemistry, Radioresistance, Public Health, Environmental and Occupational Health, Cancer research, Radiology, Nuclear Medicine and imaging
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15
المؤلفون: Aykut Pelit, Ahmet Sevki Taskiran, Ercan Ozdemir, Ayse Demirkazik, Gokhan Arslan
المساهمون: Ondokuz Mayıs Üniversitesi, Çukurova Üniversitesi
المصدر: Nitric Oxide. 92:49-54
مصطلحات موضوعية: Male, 0301 basic medicine, Analgesic effect, Cancer Research, NOS inhibitor, Arginine, Pyridines, Physiology, Clinical Biochemistry, Analgesic, Nitric oxide pathway, Pain, 030204 cardiovascular system & hematology, Pharmacology, Nitric Oxide, Biochemistry, No donors, 03 medical and health sciences, Electromagnetic Fields, 0302 clinical medicine, Electromagnetic field, Animals, Pain Management, Extremely low frequency, Rats, Wistar, Chemistry, Temperature, Rats, NG-Nitroarginine Methyl Ester, 030104 developmental biology, Nitric Oxide Pathway, Pyrazoles, Thermal pain, Analgesia, Injections, Intraperitoneal, Signal Transduction
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16
المؤلفون: T S Podosinnikova, Makarchuk Vm, Shevchenko Li, A.S. Samsonova, Filimonova Mv, A. S. Filimonov
المصدر: Bulletin of Experimental Biology and Medicine. 168:92-94
مصطلحات موضوعية: 0301 basic medicine, NOS inhibitor, Antineoplastic Agents, Adaptive potential, Pharmacology, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, No synthase, medicine, Animals, Cytotoxic T cell, Neoplasm, Tumor growth, Carcinoma, Ehrlich Tumor, Dichloroacetic Acid, Hydrobromide, Chemistry, Thiourea, Pyruvate Dehydrogenase Acetyl-Transferring Kinase, General Medicine, medicine.disease, 030104 developmental biology, Female, Nitric Oxide Synthase, 030217 neurology & neurosurgery
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17Academic Journal
مصطلحات موضوعية: antidepressant, behaviour, depression, forced swimming test, nitric oxide synthase, serotonin, 5-ht1a receptor antagonist, oxide synthase inhibitors, dorsal raphe nucleus, anxiolytic-like, tryptophan-hydroxylase, in-vivo, nos inhibitor, fluoxetine, stress, brain
Relation: Pharmacology Biochemistry and Behavior; Gigliucci, Valentina; Buckley, Kathleen Niamh; Nunan, John; O'Shea, Karen; Harkin, Andrew (2010). A role for serotonin in the antidepressant activity of ng-nitro-l-arginine, in the rat forced swimming test. Pharmacology Biochemistry and Behavior 94 (4), 524-533; http://hdl.handle.net/10379/11631
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18
المؤلفون: Filimonova, Marina, Shevchenko, Ljudmila, Filimonov, Alexander, Makarchuk, Victoria, Saburova, Alina, Koryakin, Sergey
المصدر: The Future of Radiological Protection Digital Workshop, 14 October - 3 November, 2021
مصطلحات موضوعية: radiation pathologies, selective radioprotector, safety, NOS inhibitor, combined use
Relation: https://doi.org/10.5281/zenodo.5644077; https://doi.org/10.5281/zenodo.5644078; oai:zenodo.org:5644078
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19
المؤلفون: Saurav Bhowmick, Kelly L. Drew
المصدر: Free Radical Biology and Medicine. 113:203-211
مصطلحات موضوعية: Male, 0301 basic medicine, Programmed cell death, NOS inhibitor, Oxidative phosphorylation, Hippocampal formation, Pharmacology, Hippocampus, Biochemistry, Article, Nitric oxide, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Peroxynitrous Acid, Physiology (medical), Animals, Cell Death, Superoxide, Sciuridae, Rats, Oxygen, Disease Models, Animal, Oxidative Stress, Glucose, 030104 developmental biology, nervous system, chemistry, Nitrosative Stress, Brain Injuries, Reperfusion Injury, Hypoxia-Ischemia, Brain, Female, Oxygen glucose deprivation, Food Deprivation, 030217 neurology & neurosurgery, Peroxynitrite
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20
المؤلفون: Mustafa Emre, M. Ata Seçilmiş, Eda Karabal Kumcu, İhsan Bayel, Olcay Kıroğlu, Ozlem Yorulmaz Ozü
المساهمون: Çukurova Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kıroğlu, Olcay Gürhan, Yorulmaz Özü, Özlem, Emre, Mustafa, Bayel, İhsan, Karabal Kumcu, Eda, Seçilmiş, M. Ata, Çukurova Üniversitesi
مصطلحات موضوعية: 0301 basic medicine, Male, Cancer Research, NOS inhibitor-insensitive residual NO, Vascular smooth muscle, Contraction (grammar), Endothelium, Physiology, Clinical Biochemistry, 030204 cardiovascular system & hematology, Pharmacology, Nitric Oxide, Isometric contraction, Biochemistry, Benzoates, Nitroarginine, Membrane Potentials, 03 medical and health sciences, Phenylephrine, 0302 clinical medicine, Hydroxocobalamin, medicine, Animals, Rats, Wistar, Mesenteric arteries, Protein Kinase Inhibitors, Membrane potential, biology, Chemistry, Mesenteric artery, Imidazoles, Depolarization, Free Radical Scavengers, Mesenteric Arteries, Nitric oxide synthase, 030104 developmental biology, medicine.anatomical_structure, NG-Nitroarginine Methyl Ester, Anesthesia, biology.protein, Adrenergic alpha-1 Receptor Agonists, medicine.symptom, Nitric Oxide Synthase, Vasoconstriction, medicine.drug, Muscle Contraction
وصف الملف: application/pdf