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1
المؤلفون: Babu Suresh D, R. Kuvelkar, Yuhua Huang, A.W. Stamford, Qi Zhang, Lili Zhang, P. Gaspari, J. Pan, Wang Lingyan, L. Ozgur, Ge Li, Yusheng Wu, Johannes H. Voigt, Xiao Chen, Kurt W. Saionz, J. Lowrie, Tao Guo, Ulrich Iserloh, N.A. McHugh, D. Tadesse, Le Thuy X H, Matthew E. Kennedy, Doug W. Hobbs, Leonard Favreau, Carolyn DiIanni Carroll, Corey Strickland, Jared N. Cumming, Eric M. Parker
المصدر: Bioorganic & Medicinal Chemistry Letters. 18:3236-3241
مصطلحات موضوعية: Models, Molecular, Imidazolidinone, medicine.drug_class, Stereochemistry, Peptidomimetic, Memapsin-2, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Mice, Transgenic, Carboxamide, Crystallography, X-Ray, Imidazolidines, Biochemistry, Piperazines, Mice, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Molecular Biology, Molecular Structure, Chemistry, Organic Chemistry, Rational design, Disease Models, Animal, Drug Design, β secretase, Molecular Medicine, Amyloid Precursor Protein Secretases, Aspartic Endopeptidases
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2
المؤلفون: Gary F. Merrill, A. Solowiej, N.A. McHugh, Richard E. Klabunde
المصدر: Basic Research in Cardiology. 93:470-476
مصطلحات موضوعية: Male, medicine.medical_specialty, Heart disease, Physiology, medicine.drug_class, medicine.medical_treatment, Ischemia, Angina, Dogs, Coronary Circulation, Physiology (medical), Internal medicine, Animals, Medicine, Anesthesia, cardiovascular diseases, Myocardial infarction, Estrogens, Conjugated (USP), business.industry, Hormone replacement therapy (menopause), Blood flow, medicine.disease, Endocrinology, Estrogen, Cardiology, Female, Vascular Resistance, Cardiology and Cardiovascular Medicine, business, Perfusion, hormones, hormone substitutes, and hormone antagonists
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3
المؤلفون: Qi Zhang, Lili Zhang, Johannes H. Voigt, Eric M. Parker, Matthew E. Kennedy, Corey Strickland, Leonard Favreau, Ulrich Iserloh, N.A. McHugh, J. Pan, A.W. Stamford
المصدر: Bioorganicmedicinal chemistry letters. 18(1)
مصطلحات موضوعية: Models, Molecular, Pyrrolidines, medicine.drug_class, Clinical Biochemistry, Patent literature, Pharmaceutical Science, Administration, Oral, Carboxamide, Mice, Transgenic, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Aspartate protease, Phenols, In vivo, Drug Discovery, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, Pyrrolidinones, Molecular Biology, biology, Organic Chemistry, Hydrogen Bonding, Combinatorial chemistry, Amides, Rats, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Aspartic Endopeptidases, Lead compound
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4
المؤلفون: N.A. McHugh, S. Vessie, I. Vanterpool, Sylvie Gosselin, Mutsumi Miyamoto, T. Ziegelhofer, J. Sheehan, C.M. Kelly
المصدر: Journal of Pharmacological and Toxicological Methods. 56:e9
مصطلحات موضوعية: Pharmacology, Toxicology