يعرض 1 - 20 نتائج من 32 نتيجة بحث عن '"Mzik, Martin"', وقت الاستعلام: 0.47s تنقيح النتائج
  1. 1
    Academic Journal
    Multifunctional, fluorene‐based modulator of cholinergic and GABAergic neurotransmission as a novel drug candidate for palliative treatment of Alzheimer’s disease.

    المؤلفون: Panek, Dawid, Pasieka, Anna, Jończyk, Jakub Józef, Gawlińska, Milena, Zaręba, Paula, Siwek, Agata, Wolak, Małgorzata, Mordyl, Barbara, Głuch-Lutwin, Monika, Latacz, Gniewomir, Brazzolotto, Xavier, Chantegreil, Fabien, Nachon, Florian, Zdarova Karasova, Jana, Pejchal, Jaroslav, Mzik, Martin, Sestak, Vit, Prchal, Lukas, Odvarkova, Jitka, Soukup, Ondrej, Korabecny, Jan, Sorf, Ales, Hamsikova, Marie, Zemanova, Lucie, Muckova, Lubica, Vánova, Nela, Dryja, Pola, Sałat, Kinga, Höfner, Georg, Wanner, Klaus, Więckowska, Anna, Malawska, Barbara

    المصدر: Angewandte Chemie International Edition ; ISSN 1433-7851 1521-3773

    الاتاحة: http://dx.doi.org/10.1002/anie.202420510
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202420510

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  2. 2
    Academic Journal
    The New Acetylcholinesterase Inhibitors PC‐37 and PC‐48 (7‐Methoxytacrine‐Donepezil‐Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats

    المؤلفون: Zdarova Karasova, Jana, Mzik, Martin, Hroch, Milos, Korabecny, Jan, Nepovimova, Eugenie, Vorisek, Viktor, Palicka, Vladimir, Kuca, Kamil

    المساهمون: Ministerstvo Zdravotnictví Ceské Republiky

    المصدر: Basic & Clinical Pharmacology & Toxicology ; volume 122, issue 4, page 373-382 ; ISSN 1742-7835 1742-7843

    الاتاحة: http://dx.doi.org/10.1111/bcpt.12922
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fbcpt.12922
    https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcpt.12922

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  3. 3
    Academic Journal
    Differential adsorption of an analyte and its D4, D5 and 13C6 labeled analogues combined with instrument-specific carry-over issues: The Achilles' heel of ibrutinib TDM

    المؤلفون: Mžik, Martin, Váňová, Nela, Kriegelstein, Michal, Hroch, Miloš

    المساهمون: European Commission, Ministry of Education Youth and Sports of the Czech Republic, Univerzita Karlova v Praze

    المصدر: Journal of Pharmaceutical and Biomedical Analysis ; volume 206, page 114366 ; ISSN 0731-7085

    الاتاحة: http://dx.doi.org/10.1016/j.jpba.2021.114366
    https://api.elsevier.com/content/article/PII:S0731708521004775?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0731708521004775?httpAccept=text/plain

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  4. 4
    Academic Journal
    In vitro and in vivo metabolism of 3-quinuclidinyl benzilate by high-resolution mass spectrometry

    المؤلفون: Uher, Martin, Mžik, Martin, Karasová, Jana Žďárová, Herman, David, Čechová, Lenka, Dlabková, Alžběta, Mrkvicová, Alena, Hroch, Miloš

    المساهمون: Charles University, Prague, Ministry of Defense, Prague

    المصدر: Journal of Pharmaceutical and Biomedical Analysis ; volume 190, page 113519 ; ISSN 0731-7085

    الاتاحة: http://dx.doi.org/10.1016/j.jpba.2020.113519
    https://api.elsevier.com/content/article/PII:S0731708520314059?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0731708520314059?httpAccept=text/plain

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  5. 5
    Academic Journal
    Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease

    المؤلفون: Chalupova, Katarina, Korabecny, Jan, Bartolini, Manuela, Monti, Barbara, Lamba, Doriano, Caliandro, Rosanna, Pesaresi, Alessandro, Brazzolotto, Xavier, Gastellier, Anne-Julie, Nachon, Florian, Pejchal, Jaroslav, Jarosova, Michaela, Hepnarova, Vendula, Jun, Daniel, Hrabinova, Martina, Dolezal, Rafael, Zdarova Karasova, Jana, Mzik, Martin, Kristofikova, Zdena, Misik, Jan, Muckova, Lubica, Jost, Petr, Soukup, Ondrej, Benkova, Marketa, Setnicka, Vladimir, Habartova, Lucie, Chvojkova, Marketa, Kleteckova, Lenka, Vales, Karel, Mezeiova, Eva, Uliassi, Elisa, Valis, Martin, Nepovimova, Eugenie, Bolognesi, Maria Laura, Kuca, Kamil

    المساهمون: Ministry of Health of the Czech Republic, University of Defence, European Regional Development Fund, the Direction Générale de l’Armement (DGA), Service de Santé des Armées (SSA)

    المصدر: European Journal of Medicinal Chemistry ; volume 168, page 491-514 ; ISSN 0223-5234

    الاتاحة: http://dx.doi.org/10.1016/j.ejmech.2019.02.021
    https://api.elsevier.com/content/article/PII:S0223523419301357?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0223523419301357?httpAccept=text/plain

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  6. 6
    Dissertation/ Thesis
    Bioanalytické hodnocení nových inhibitorů acetylcholinesteráz ; Bioanalytical Evaluation of New Acetylcholinesterase Inhibitors

    المؤلفون: Mžik, Martin

    المساهمون: Palička, Vladimír, Maier, Vítězslav, Kučera, Radim, Žďárová Karasová, Jana

    وصف الملف: application/pdf; application/zip

    Relation: http://hdl.handle.net/20.500.11956/111524; 119555; 002299607; 990022996070106986

    الاتاحة: https://hdl.handle.net/20.500.11956/111524

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  7. 7
    Academic Journal
    1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats

    المؤلفون: Zdarova Karasova, Jana, Sestak, Vit, Korabecny, Jan, Mezeiova, Eva, Palicka, Vladimir, Kuca, Kamil, Mzik, Martin

    المساهمون: Ministry of Defense, Czech Republic, University Hospital Hradec Kralove

    المصدر: Journal of Chromatography B ; volume 1092, page 350-358 ; ISSN 1570-0232

    الاتاحة: http://dx.doi.org/10.1016/j.jchromb.2018.06.034
    https://api.elsevier.com/content/article/PII:S1570023218306342?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S1570023218306342?httpAccept=text/plain

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  8. 8
    Academic Journal
    An HPLC–MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study

    المؤلفون: Mzik, Martin, Korabecny, Jan, Nepovimova, Eugenie, Voříšek, Viktor, Palička, Vladimir, Kuca, Kamil, Zdarova Karasova, Jana

    المصدر: Journal of Chromatography B ; volume 1020, page 85-89 ; ISSN 1570-0232

    الاتاحة: http://dx.doi.org/10.1016/j.jchromb.2016.02.038
    https://api.elsevier.com/content/article/PII:S1570023216301258?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S1570023216301258?httpAccept=text/plain

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  9. 9
    Academic Journal
    Aberrant methylation of tumour suppressor genes WT1, GATA5 and PAX5 in hepatocellular carcinoma

    المؤلفون: Mžik, Martin, Chmelařová, Marcela, John, Stanislav, Laco, Jan, Slabý, Ondřej, Kiss, Igor, Bohovicová, Lucia, Palička, Vladimír, Nekvindová, Jana

    المصدر: Clinical Chemistry and Laboratory Medicine (CCLM) ; volume 54, issue 12, page 1971-1980 ; ISSN 1437-4331 1434-6621

    الاتاحة: http://dx.doi.org/10.1515/cclm-2015-1198
    http://www.degruyter.com/view/j/cclm.2016.54.issue-12/cclm-2015-1198/cclm-2015-1198.xml
    https://www.degruyter.com/document/doi/10.1515/cclm-2015-1198/xml
    https://www.degruyter.com/document/doi/10.1515/cclm-2015-1198/pdf

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  10. 10
    Academic Journal
    Effect of Mirtazapine on Rat Bone Tissue after Orchidectomy

    المؤلفون: Fekete, Sona, Simko, Julius, Mzik, Martin, Karesova, Iva, Zivna, Helena, Pavlíková, Ladislava, Palicka, Vladimir

    المصدر: Pharmacology ; volume 95, issue 3-4, page 166-172 ; ISSN 0031-7012 1423-0313

    الاتاحة: http://dx.doi.org/10.1159/000380953
    https://www.karger.com/Article/Pdf/380953

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  11. 11
    Academic Journal
    Negative effect of serotonin–norepinephrine reuptake inhibitor therapy on rat bone tissue after orchidectomy

    المؤلفون: Fekete, Sona, Simko, Julius, Mzik, Martin, Karesova, Iva, Zivna, Helena, Zivny, Pavel, Pavliková, Ladislava, Palicka, Vladimir

    المساهمون: Research Project of PRVOUK, Charles University in Prague project

    المصدر: European Journal of Pharmacology ; volume 761, page 65-69 ; ISSN 0014-2999

    الاتاحة: http://dx.doi.org/10.1016/j.ejphar.2015.04.029
    https://api.elsevier.com/content/article/PII:S0014299915003738?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0014299915003738?httpAccept=text/plain

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  12. 12
    Academic Journal
    The New Acetylcholinesterase Inhibitors PC‐37 and PC‐48 (7‐Methoxytacrine‐Donepezil‐Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats

    المؤلفون: Zdarova Karasova, Jana, Mzik, Martin, Hroch, Milos, Korabecny, Jan, Nepovimova, Eugenie, Vorisek, Viktor, Palicka, Vladimir, Kuca, Kamil

    المصدر: Basic & Clinical Pharmacology & Toxicology; Apr2018, Vol. 122 Issue 4, p373-382, 10p

    مصطلحات موضوعية: PHARMACOKINETICS, ALZHEIMER'S patients, METABOLITES, ACETYLCHOLINESTERASE inhibitors, MICROSOMES


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  13. 13
    Dissertation/ Thesis
    Stanovení aktivit estradioldehydrogenas a estronreduktas ; Estradiol dehydrogenases and estrone reductases activity assays

    المؤلفون: Mžik, Martin

    المساهمون: Skálová, Lenka, Dršata, Jaroslav

    وصف الملف: application/pdf

    Relation: http://hdl.handle.net/20.500.11956/33542; 80967; 001365215; 990013652150106986

    الاتاحة: https://hdl.handle.net/20.500.11956/33542

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  14. 14
    Dissertation/ Thesis
    HPLC analýza exogenních látek ; HPLC analysis of exogenic compounds

    المؤلفون: Mžik, Martin

    المساهمون: Sochor, Jaroslav, Kovaříková, Petra

    وصف الملف: application/pdf

    Relation: http://hdl.handle.net/20.500.11956/29136; 51397; 001384388; 990013843880106986

    الاتاحة: https://hdl.handle.net/20.500.11956/29136

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  15. 15
    Academic Journal
    Interaction of Cucurbit[7]uril with Oxime K027, Atropine, and Paraoxon: Risky or Advantageous Delivery System?

    المؤلفون: Zdarova Karasova, Jana1,2 (AUTHOR) vecera.zbyna@gmail.com, Mzik, Martin3 (AUTHOR) martin.mzik@fnhk.cz, Kucera, Tomas4 (AUTHOR) tomas.kucera2@unob.cz, Vecera, Zbynek1 (AUTHOR) jiri.kassa@unob.cz, Kassa, Jiri1 (AUTHOR), Sestak, Vit3 (AUTHOR) vit.sestak@fnhk.cz

    المصدر: International Journal of Molecular Sciences. Nov2020, Vol. 21 Issue 21, p7883. 1p.

    مصطلحات موضوعية: *CUCURBITACEAE, *ATROPINE, *PARAOXON, *CENTRAL nervous system, *OXIMES, *DRUG delivery systems, *BLOOD-brain barrier

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  16. 16
    Dissertation/ Thesis
    Bioanalytické hodnocení nových inhibitorů acetylcholinesteráz
    Bioanalytical Evaluation of New Acetylcholinesterase Inhibitors

    المؤلفون: Mžik, Martin

    Thesis Advisors: Palička, Vladimír, Maier, Vítězslav, Kučera, Radim

    الاتاحة: http://www.nusl.cz/ntk/nusl-408310

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  17. 17
    Dissertation/ Thesis
    Stanovení aktivit estradioldehydrogenas a estronreduktas
    Estradiol dehydrogenases and estrone reductases activity assays

    المؤلفون: Mžik, Martin

    Thesis Advisors: Skálová, Lenka, Dršata, Jaroslav

    الاتاحة: http://www.nusl.cz/ntk/nusl-298019

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  18. 18
    Dissertation/ Thesis
    UHPLC-HRMS analýza kanabinoidů v biologické matrici ; UHPLC-HRMS analysis of cannabinoids in biological matrix

    المؤلفون: Ocelková, Anna

    المساهمون: Kučera, Radim, Bavlovič Piskáčková, Hana, Mžik, Martin

    مصطلحات موضوعية: Kanabinoidy, LC-HRMS, Bioanalýza, Validace, Cannabinoids, Bioanalysis, Validation

    وصف الملف: application/pdf

    Relation: http://hdl.handle.net/20.500.11956/173237; 232124

    الاتاحة: https://hdl.handle.net/20.500.11956/173237

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  19. 19
    Dissertation/ Thesis
    LC-HRMS analýza vybraných léčiv v biologickém materiálu II. ; LC-HRMS analysis of selected drugs in biological material II.

    المؤلفون: Švarcová, Kristýna

    المساهمون: Kučera, Radim, Bavlovič Piskáčková, Hana, Mžik, Martin

    مصطلحات موضوعية: LC-HRMS, drugs, léčiv

    وصف الملف: application/pdf

    Relation: http://hdl.handle.net/20.500.11956/121062; 196781; 002383322; 990023833220106986

    الاتاحة: https://hdl.handle.net/20.500.11956/121062

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  20. 20
    LC-HRMS analýza vybraných antihypertenziv v biologickém materiálu jako průkaz compliance ; LC-HRMS analysis of selected antihypertensive drugs in biological material for compliance assessment

    المؤلفون: Tláskalová, Anna

    المساهمون: Kučera, Radim, Štěrbová, Petra, Mžik, Martin

    مصطلحات موضوعية: LC-HRMS, antihypertensive drugs, antihypertenziva

    وصف الملف: application/pdf

    Relation: http://hdl.handle.net/20.500.11956/112097; 212216; 002302846; 990023028460106986

    الاتاحة: https://hdl.handle.net/20.500.11956/112097

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