المؤلفون: Julia Doll, Michaela A. H. Hofrichter, Paulina Bahena, Alfred Heihoff, Dennis Segebarth, Tobias Müller, Marcus Dittrich, Thomas Haaf, Barbara Vona

المصدر: Molecular Genetics & Genomic Medicine, Vol 8, Iss 8, Pp n/a-n/a (2020)

مصطلحات موضوعية: autosomal dominant nonsyndromic hearing loss, MYO3A, myosin IIIA, progressive hearing loss, sensorineural hearing loss, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2324-9269

URL الوصول: https://doaj.org/article/e3a28149327449109b326fcf9b72c593

المؤلفون: Barbara Vona, Alfred Heihoff, Thomas Haaf, Michaela A.H. Hofrichter, Marcus Dittrich, Tobias Müller, Paulina Bahena, Dennis Segebarth, Julia Doll

المصدر: Molecular Genetics & Genomic Medicine, Vol 8, Iss 8, Pp n/a-n/a (2020)
Molecular Genetics & Genomic Medicine

مصطلحات موضوعية: Male, 0301 basic medicine, Proband, lcsh:QH426-470, Hearing loss, Hearing Loss, Sensorineural, Mutation, Missense, autosomal dominant nonsyndromic hearing loss, 030105 genetics & heredity, Biology, Myosin IIIA, Clinical Reports, sensorineural hearing loss, 03 medical and health sciences, Protein Domains, Genetics, medicine, otorhinolaryngologic diseases, Humans, Missense mutation, Myosin Type III, Molecular Biology, Gene, Genetics (clinical), Exome sequencing, Genes, Dominant, Clinical Report, Myosin Heavy Chains, Auditory Threshold, medicine.disease, Pedigree, lcsh:Genetics, 030104 developmental biology, myosin IIIA, Hearing level, progressive hearing loss, Female, Sensorineural hearing loss, medicine.symptom, MYO3A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c2aeeca3c490155301ddede1b4dfb5
https://doaj.org/article/e3a28149327449109b326fcf9b72c593

المؤلفون: Li Jin, Ruizhi Feng, Yao Xu, Lei Wang, Lin He, Qing Sang, Ronggui Qu

المصدر: International Journal of Pediatric Otorhinolaryngology. 84:43-47

مصطلحات موضوعية: Genetic Markers, Male, 0301 basic medicine, China, Hearing loss, Hearing Loss, Sensorineural, Mutation, Missense, Consanguinity, Deafness, Biology, Myosin IIIA, Congenital hearing loss, 03 medical and health sciences, otorhinolaryngologic diseases, medicine, Humans, Missense mutation, Myosin Type III, Gene, Genetics, Myosin Heavy Chains, 030102 biochemistry & molecular biology, Homozygote, General Medicine, Phenotype, Kazakhstan, 030104 developmental biology, Otorhinolaryngology, Child, Preschool, Pediatrics, Perinatology and Child Health, Mutation (genetic algorithm), Female, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d32fb0f7457df780acf5745dfd71f919
https://doi.org/10.1016/j.ijporl.2016.02.036

المؤلفون: Felipe T. Salles, Raymond C. Merritt, Uri Manor, Gerard W. Dougherty, Christopher M. Yengo, Andréa C. Dosé, Aurea D. Sousa, Bechara Kachar, Judy E. Moore

المصدر: Nature cell biology

مصطلحات موضوعية: ESPN, Myosin IIIA, Protein filament, Mice, myosin IIIa, 0302 clinical medicine, length regulation, Chlorocebus aethiops, Myosin, Pseudopodia, 0303 health sciences, actin polymerization, Microfilament Proteins, actin protrusion, Ankyrin Repeat, 3. Good health, Cell biology, Actin Cytoskeleton, Protein Transport, medicine.anatomical_structure, COS Cells, WH2 motif, MYO3A, Protein Binding, Myosin light-chain kinase, hair cells, macromolecular substances, Biology, Transfection, espin, Article, 03 medical and health sciences, filopodia, deafness, otorhinolaryngologic diseases, medicine, Animals, Myosin Type III, Inner ear, Cilia, stereocilia, Actin, 030304 developmental biology, Stereocilia, Actin remodeling, Cell Biology, Rats, hearing, sense organs, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20efe4ce1abaf864f69dd3c754daa228
https://doi.org/10.1038/ncb1851

المؤلفون: Shigeru Komaba, Sei Kobayashi, Byung Chull An, Reiko Ikebe, Jin Young Kim, Mistuo Ikebe, Hiroko Kishi, Tsuyoshi Sakai

المصدر: Biochemistry

مصطلحات موضوعية: Models, Molecular, Threonine, Myosin light-chain kinase, macromolecular substances, Biology, Myosin IIIA, Microfilament, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Catalytic Domain, Okadaic Acid, Myosin, Animals, Humans, Myosin Type III, Protein Interaction Domains and Motifs, Enzyme Inhibitors, Phosphorylation, Kinase activity, Furans, 030304 developmental biology, 0303 health sciences, Microvilli, Myosin Heavy Chains, Protein Stability, Autophosphorylation, Actin remodeling, Lipids, Recombinant Proteins, Cell biology, Actin Cytoskeleton, Protein Transport, Enterocytes, Amino Acid Substitution, Protein kinase domain, Mutant Proteins, Rabbits, Caco-2 Cells, Protein Processing, Post-Translational, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a020f889810045432d1b0ef3835ce32
https://doi.org/10.1021/bi501247z

المؤلفون: Brian M. McDermott, Lana M. Pollock, Shih Wei Chou

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: 0301 basic medicine, Stereocilia (inner ear), Sensory system, macromolecular substances, Biology, Myosin IIIA, Article, Stereocilia, 03 medical and health sciences, Auditory Hair Cell, Hair Cells, Auditory, Myosin, otorhinolaryngologic diseases, Molecular motor, Animals, Humans, Myosin Type III, Research Articles, Microvilli, Myosin Heavy Chains, MYOSIN IIIB, Cell Biology, Anatomy, 3. Good health, Cell biology, 030104 developmental biology, sense organs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd95dceb4374542394bb63e966905f05
https://doi.org/10.1083/jcb.201512086

المؤلفون: Uri Manor, William C. Unrath, M'hamed Grati, Raymond C. Merritt, Felipe T. Salles, Andréa C. Dosé, Bechara Kachar, Christopher M. Yengo, Omar A. Quintero

المصدر: Current Biology. 22(4):320-325

مصطلحات موضوعية: Myosin Heavy Chains, Agricultural and Biological Sciences(all), Biochemistry, Genetics and Molecular Biology(all), Microfilament Proteins, Motility, macromolecular substances, Myosin IIIA, Biology, Actin cytoskeleton, Article, General Biochemistry, Genetics and Molecular Biology, Cell biology, Actin Cytoskeleton, Myosin, Animals, Humans, Myosin Type III, Pseudopodia, General Agricultural and Biological Sciences, Filopodia, Actin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78644d8111df9c59668bc071109fcdd7

المؤلفون: Tom Walsh, Amiel A. Dror, Dorith Raviv, Moien Kanaan, Hashem Shahin, Vanessa Walsh, Karen B. Avraham, Mary Claire King

المصدر: Mamm Genome

مصطلحات موضوعية: Male, Hearing loss, Stereocilia (inner ear), Molecular Sequence Data, Myosin IIIA, Biology, medicine.disease_cause, Compound heterozygosity, Article, Mice, Evoked Potentials, Auditory, Brain Stem, otorhinolaryngologic diseases, Genetics, medicine, Animals, Humans, Myosin Type III, Hearing Loss, Loss function, Mice, Knockout, Mutation, Base Sequence, Myosin Heavy Chains, Age Factors, Phenotype, Molecular biology, Protein Structure, Tertiary, Mice, Inbred C57BL, Disease Models, Animal, Protein kinase domain, Female, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d96e5f7ba929b1ca9ff7b0556abf0957
https://doi.org/10.1007/s00335-010-9310-6

المؤلفون: Asadollah Aghaie, Typhaine Dupont, Paul Avan, Matteo Cortese, Christine Petit, Andrea Lelli, Jacques Boutet de Monvel, Vincent Michel, Montserrat Bosch-Grau, Isabelle Perfettini, Aziz El-Amraoui

المساهمون: Collège de France - Chaire Génétique et physiologie cellulaire, Collège de France (CdF (institution)), Institut de la Vision, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre Jean Perrin [Clermont-Ferrand] (UNICANCER/CJP), UNICANCER, Equipe Biophysique Neurosensorielle [Neuro-Dol], Neuro-Dol (Neuro-Dol), Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université d'Auvergne - Clermont-Ferrand I (UdA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Neuro-Dol (Neuro-Dol), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Université Clermont Auvergne [2017-2020] (UCA [2017-2020]), This research was funded by the European Research Council (advanced grant 'Hair bundle,' ERC-2011-AdG294570), the Agence Nationale de la Recherche (ANR, grant EARMEC, ANR-11-BSV5-0011), ANR program 'Investissements d'Avenir' (grant ANR-10-LABX-65), Errera Hoechstetter, and the Foundation BNP Paribas., ANR-11-BSV5-0011,EARMEC,Propriétés mécaniques, actives et passives, de la touffe ciliaire des cellules mécano-sensorielles ciliées le long de l'axe tonotopique de la cochlée des mammifères.(2011), ANR-11-IDEX-0004,SUPER,Sorbonne Universités à Paris pour l'Enseignement et la Recherche(2011), European Project: 294570,EC:FP7:ERC,ERC-2011-ADG_20110310,HAIRBUNDLE(2012), Chaire Génétique et physiologie cellulaire, Oficjalska, Danuta, BLANC - Propriétés mécaniques, actives et passives, de la touffe ciliaire des cellules mécano-sensorielles ciliées le long de l'axe tonotopique de la cochlée des mammifères. - - EARMEC2011 - ANR-11-BSV5-0011 - BLANC - VALID, Sorbonne Universités à Paris pour l'Enseignement et la Recherche - - SUPER2011 - ANR-11-IDEX-0004 - IDEX - VALID, Assembling the puzzle of the operating auditory hair bundle - HAIRBUNDLE - - EC:FP7:ERC2012-12-01 - 2017-11-30 - 294570 - VALID

المصدر: Journal of Cell Biology
Journal of Cell Biology, 2016, 212 (2), pp.231-44. ⟨10.1083/jcb.201509017⟩
Journal of Cell Biology, Rockefeller University Press, 2016, 212 (2), pp.231-44. ⟨10.1083/jcb.201509017⟩
The Journal of Cell Biology

مصطلحات موضوعية: 0301 basic medicine, Physiology, [SDV]Life Sciences [q-bio], Molecular Sequence Data, Morphogenesis, Reviews, audition, Biology, Myosin IIIA, Deafness, Stereocilia, 03 medical and health sciences, Mice, 0302 clinical medicine, unconventional myosins, Myosin, Hair Cells, Auditory, otorhinolaryngologic diseases, Animals, Humans, Myosin Type III, Amino Acid Sequence, 030304 developmental biology, Body Patterning, Mice, Knockout, Stereocilium, 0303 health sciences, Microvilli, Myosin Heavy Chains, Microfilament Proteins, Comment, Membrane Proteins, Cell Biology, Anatomy, Microfilament Protein, Mice, Mutant Strains, Cell biology, [SDV] Life Sciences [q-bio], 030104 developmental biology, HEK293 Cells, Mechanosensitive channels, sense organs, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8de1f928b9ccb1ab9311cbba946e776
https://hal-pasteur.archives-ouvertes.fr/pasteur-01317988

المؤلفون: Bechara Kachar, Felipe T. Salles, Jessica Waguespack, Anthony J. Ricci

المصدر: The Journal of Neuroscience. 27:13890-13902

مصطلحات موضوعية: Time Factors, Myosins, Myosin IIIA, Biology, Mechanotransduction, Cellular, Rats, Sprague-Dawley, Organ Culture Techniques, Physical Stimulation, Myosin, otorhinolaryngologic diseases, medicine, Animals, Inner ear, Mechanotransduction, Cochlea, General Neuroscience, Cell Differentiation, Articles, Anatomy, Rats, Cell biology, Electrophysiology, Hair Cells, Auditory, Outer, medicine.anatomical_structure, Animals, Newborn, Organ of Corti, sense organs, Transduction (physiology), Tip link

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ef59656b26b63b8a4c449c9dbc9871
https://doi.org/10.1523/jneurosci.2159-07.2007

المؤلفون: Judy E. Moore, Shobana K. Ananthanarayanan, Christopher M. Yengo, Beth Burnside, Andréa C. Dosé

المصدر: Journal of Biological Chemistry. 282:216-231

مصطلحات موضوعية: Myosin light-chain kinase, Light, Protein Conformation, ATPase, Amino Acid Motifs, macromolecular substances, Myosins, Biology, Myosin IIIA, Biochemistry, Phosphates, Protein structure, Humans, Scattering, Radiation, Myosin Type III, Enzyme kinetics, Phosphorylation, Molecular Biology, Actin, Dose-Response Relationship, Drug, Kinase, Cell Biology, Actins, Protein Structure, Tertiary, Kinetics, Spectrometry, Fluorescence, Models, Chemical, Biophysics, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e22b52fc8e8f77b9685c1e24584906
https://doi.org/10.1074/jbc.m605964200

المؤلفون: Amoreena C. Corsa, Beth Burnside, F. Les Erickson, Andréa C. Dosé

المصدر: Molecular Biology of the Cell. 14:4173-4180

مصطلحات موضوعية: Calmodulin, Recombinant Fusion Proteins, DNA Mutational Analysis, Green Fluorescent Proteins, Molecular Sequence Data, Fluorescent Antibody Technique, macromolecular substances, Plasma protein binding, Myosin IIIA, Myosin, Humans, Myosin Type III, Amino Acid Sequence, Pseudopodia, Molecular Biology, Cellular localization, DNA Primers, biology, Articles, Cell Biology, Transfection, Actins, Protein Structure, Tertiary, Cell biology, Luminescent Proteins, Cytoplasm, biology.protein, Filopodia, HeLa Cells, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22eb5bea594ff4ecb4daebd2133cbd7f
https://doi.org/10.1091/mbc.e02-10-0656

المؤلفون: Christopher M. Yengo, Joseph E. O'Tousa, Stephanie A. Freed, Manmeet H. Raval, Kirk L. Mecklenburg, Omar A. Quintero

المصدر: PLoS ONE, Vol 10, Iss 3, p e0122502 (2015)
PLoS ONE

مصطلحات موضوعية: lcsh:Medicine, Biology, Myosin IIIA, Cell Line, Motor protein, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Chlorocebus aethiops, Myosin, Animals, Drosophila Proteins, Myosin Type III, Photoreceptor Cells, Pseudopodia, Binding site, Eye Proteins, lcsh:Science, Actin, Adaptor Proteins, Signal Transducing, 030304 developmental biology, Genetics, 0303 health sciences, Binding Sites, Multidisciplinary, Cell Membrane, lcsh:R, Signal transducing adaptor protein, Invertebrates, Protein Structure, Tertiary, Cell biology, COS Cells, Vertebrates, Drosophila, lcsh:Q, Filopodia, 030217 neurology & neurosurgery, Research Article, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b033823d1a7531dae076e89a1a0e8994
http://europepmc.org/articles/PMC4379085?pdf=render

المؤلفون: Kwok Peng Ng, Taketoshi Kambara, Mitsuo Ikebe, Motoi Matsuura, Morris Burke

المصدر: Biochemistry. 35:9392-9399

مصطلحات موضوعية: Myosin light-chain kinase, Molecular Sequence Data, Magnesium Chloride, macromolecular substances, Sodium Chloride, Myosin IIIA, Mitogen-activated protein kinase kinase, Biochemistry, Substrate Specificity, Adenosine Triphosphate, Myosin, Animals, Drosophila Proteins, Amino Acid Sequence, c-Raf, Cloning, Molecular, Phosphorylation, Kinase activity, Eye Proteins, Rho-associated protein kinase, Myosin Heavy Chains, Chemistry, Hydrogen-Ion Concentration, Chromatography, Ion Exchange, Molecular Weight, Drosophila, Electrophoresis, Polyacrylamide Gel, Cyclin-dependent kinase 9, Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9266f3e9b9c3f8f259aeb449fee7e19
https://doi.org/10.1021/bi960181a

المؤلفون: Mitsuo Ikebe, Tsuyoshi Sakai, Munenori Ishibashi, Reiko Ikebe

المصدر: Biophysical Journal. 112:267a

مصطلحات موضوعية: Motor protein, medicine.anatomical_structure, Protein kinase domain, Stereocilia, Myosin, Biophysics, medicine, Inner ear, Biology, Myosin IIIA, Filopodia, Actin, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::32647ed8335c6c0d61ee99c36e6e79f4
https://doi.org/10.1016/j.bpj.2016.11.1450

المؤلفون: Pavel I. Zhuravlev, Maria Minakova, Garegin A. Papoian, Yueheng Lan

مصطلحات موضوعية: Models, Molecular, Multidisciplinary, Molecular Motor Proteins, Stereocilia, Biological Transport, Active, Mechanics, Biology, Myosin IIIA, Biological Sciences, Actin cytoskeleton, Actins, Cell biology, Actin Cytoskeleton, Molecular motor, Animals, Humans, Pseudopodia, Boundary value problem, Diffusion (business), Filopodia, Algorithms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6b814b2a3e5eb882c1969f2482b716d
https://europepmc.org/articles/PMC3390872/

المؤلفون: Craig Montell, Jeffery A. Porter

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: Retinal degeneration, genetic structures, Molecular Sequence Data, Myosin IIIA, Biology, Myosins, Transfection, Myosin, medicine, Electroretinography, Animals, Drosophila Proteins, Point Mutation, Photoreceptor Cells, Amino Acid Sequence, Protein kinase A, Eye Proteins, Alleles, Base Sequence, Myosin Heavy Chains, Temperature, Cell Biology, Articles, medicine.disease, Rhabdomere, Molecular biology, Phenotype, Protein kinase domain, Mutagenesis, Site-Directed, Drosophila, sense organs, Protein Kinases, Drosophila Protein, Visual phototransduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd4d22f8e667634776f6279f19410ca
http://europepmc.org/articles/PMC2119665

المؤلفون: M'hamed Grati, Omar A. Quintero, Uri Manor, Christopher M. Yengo, Judy E. Moore, Felipe T. Salles, Bechara Kachar, William C. Unrath

المصدر: The Journal of biological chemistry. 285(46)

مصطلحات موضوعية: Recombinant Fusion Proteins, Blotting, Western, Green Fluorescent Proteins, Arp2/3 complex, macromolecular substances, Biology, Myosin IIIA, Transfection, Biochemistry, Actin remodeling of neurons, Hair Cells, Vestibular, Myosin, Chlorocebus aethiops, Animals, Humans, Myosin Type III, Actin-binding protein, Amino Acid Sequence, Pseudopodia, Phosphorylation, Molecular Biology, Organ of Corti, Cellular localization, Myosin Heavy Chains, Autophosphorylation, Actin remodeling, Cell Biology, Actins, Cell biology, Rats, Microscopy, Fluorescence, COS Cells, Mutation, biology.protein, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::455037f1722691992fac2e8ceef57ad9
https://pubmed.ncbi.nlm.nih.gov/20826793

المؤلفون: Osamu Sato, Mitsuo Ikebe, Shinya Watanabe, Nobuhisa Umeki, Shigeru Komaba

المصدر: Biochemistry. 49(17)

مصطلحات موضوعية: Adenosine Triphosphatases, Binding Sites, Myosin Heavy Chains, Chemistry, Hydrolysis, macromolecular substances, Myosin IIIA, Biochemistry, Filamentous actin, Dissociation (chemistry), Actins, Catalysis, Article, Protein Structure, Tertiary, Dissociation constant, Kinetics, Reaction rate constant, Adenosine Triphosphate, ATP hydrolysis, Phosphorylation, Humans, Myosin Type III, Actin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978aa48dca4dfc34aa2e2d5397bdd99e
https://pubmed.ncbi.nlm.nih.gov/20192276

المؤلفون: Matthias Kloor, Michael Hoffmeister, Hans K. Schackert, Clemens Schafmayer, Stefan Schreiber, Elke Holinski-Feder, Bowang Chen, Pavel Vodicka, Alessio Naccarati, Marianne Weires, Barbara Pardini, Reinhard Büttner, Henry Völzke, Asta Försti, Ludmila Vodickova, Monika Morak, Jochen Hampe, Nils Rahner, Cristoph Engel, Nelli Kunkel, Barbara Burwinkel, Hermann Brenner, Jenny Chang-Claude, Jesús Lascorz, Kari Hemminki, Jan Novotny, Heike Görgens, Karsten Schulmann, Michael Krawczak, Verena Steinke, Timm O. Goecke, Stephan Buch, Clemens Dieter Bröring, Peter Propping

المصدر: Carcinogenesis
Carcinogenesis; Vol 31

مصطلحات موضوعية: Cancer Research, Genome-wide association study, Single-nucleotide polymorphism, Biology, Myosin IIIA, Polymorphism, Single Nucleotide, White People, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, Germany, Genotype, Genetic predisposition, Humans, Genetic Predisposition to Disease, Allele, Neoplasm Staging, 030304 developmental biology, Genetic association, Genetics, 0303 health sciences, General Medicine, Odds ratio, Prognosis, 3. Good health, Case-Control Studies, 030220 oncology & carcinogenesis, Mitogen-Activated Protein Kinases, Colorectal Neoplasms, Genome-Wide Association Study, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d25563297ba784c77ebfb0c23cfc13
http://hdl.handle.net/2318/1765147