يعرض 1 - 20 نتائج من 109 نتيجة بحث عن '"Myllymaeki, Mikko"', وقت الاستعلام: 0.62s تنقيح النتائج
  1. 1
    Academic Journal
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    Academic Journal

    المساهمون: TRIMM - Translational Immunology Research Program, Department of Clinical Chemistry and Hematology, HUS Comprehensive Cancer Center, Department of Oncology, Myllymaki_lab, Hematologian yksikkö, Research Programs Unit, Department of Medical and Clinical Genetics, Faculty Common Matters (Faculty of Medicine), Medicum, Clinicum, HUS Diagnostic Center, HUSLAB, Digital Precision Cancer Medicine (iCAN)

    وصف الملف: application/pdf

    Relation: Acknowledgments: this research was funded with research grants from the european Research council (M-iMM and StRAtiFY projects), Academy of Finland, Sigrid Juselius Foundation, cancer Foundation Finland, Blood disease Research Foundation, and instrumentarium Science Foundation. S.L. was supported by Biomedicum helsinki Foundation and Finnish Medical Foundation. We acknowledge P. ellonen from the institute of Molecular Medicine Finland (FiMM) for advice on gene panel design. We thank h. L\u00E4hteenm\u00E4ki, t. Kasanen, and J. Klievink from the hematology Research Unit helsinki for excellent technical assistance. We acknowledge J. huuhtanen for expertise and advice with tcR data analysis. Single-cell sequencing and immunogene panel sequencing were performed at FiMM Single-cell Analytics and Sequencing units supported by hiLiFe and Biocenter Finland. We acknowledge the Finnish Red cross Blood Service for providing healthy control samples. the authors thank all the patients for their generous participation. We acknowledge the it center for Science Ltd. for data storage and computational resources and Aalto Science-it project for computational resources. Author contributions: conceptualization: S.L., M.A.i.K., P.S., t.K., and S.M. Methology: S.L., M.A.i.K., t.K., P.S., and J.S. validation: S.L., P.S., and M.K. Formal analysis: S.L., t.J., J.t., M.K., and J.S. investigation: S.L., M.A.i.K., P.S., d.K., h.R., and J.S. Resources: M.A.i.K., U.S., G.W., P.S., h.R., e.h.-L., M.i.-R., and S.M. data curation: S.L., M.A.i.K., U.S., G.W., P.S., h.R., and M.i.-R. visualization: S.L. Supervision: S.M., M.M., and M.K. Writing\u2014original draft: S.L. Writing\u2014review and editing: All authors. Funding acquisition: S.M. Competing interests: S.M. has received honoraria and research funding from BMS and novartis, research funding from Pfizer, and honoraria from dren-Bio (none of these are related to this project). the other authors declare that they have no competing interests. Data and materials availability: the scRnA + tcR\u03B1\u03B2-seq raw data and immunogene panel sequencing raw data have been deposited at the european Genome-phenome Archive (eGA; https://ega-archive.org), which are hosted by the eBi and the cRG, under accession numbers eGAd00001012121 and eGAd50000000352. the access is restricted and can be requested on the eGA website through the data Access committee, due to data privacy concerns. the processed scRnA + tcR\u03B1\u03B2-seq data are available in the Arrayexpress database at eMBL-eBi (www.ebi.ac.uk/arrayexpress) under accession number e-MtAB-13419. tcR\u03B2 sequencing data are available at Zenodo under 10.5281/zenodo.11106370 and 10.5281/ zenodo.11106372. All data needed to evaluate the conclusions in the paper are present in the paper and/or the Supplementary Materials.; Lundgren , S , Myllymäki , M , Järvinen , T , Keränen , M A I , Theodoropoulos , J , Smolander , J , Kim , D , Salmenniemi , U , Walldin , G , Savola , P , Kelkka , T , Rajala , H , Hellström-Lindberg , E , Itälä-Remes , M , Kankainen , M & Mustjoki , S 2024 , ' Somatic mutations associate with clonal expansion of CD8 + T cells ' , Science Advances , vol. 10 , no. 23 , eadj0787 . https://doi.org/10.1126/sciadv.adj0787; http://hdl.handle.net/10138/577711; 6f5f246b-97aa-4174-a803-20409d83f3a7; 85195534106

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    Academic Journal
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    Academic Journal

    المصدر: Journal of Medical Research (JIM); Vol. 5 No. 1 (2024): Journal of Medical Research; 26–40 ; Jornal de Investigação Médica (JIM); Vol. 5 N.º 1 (2024): Jornal de Investigação Médica; 26–40 ; 2184-7509 ; 10.29073/jim.v5i1

    وصف الملف: application/pdf

  5. 5
    Academic Journal

    المصدر: Journal of Medical Research (JIM); Vol. 5 No. 1 (2024): Journal of Medical Research; 41–56 ; Jornal de Investigação Médica (JIM); Vol. 5 N.º 1 (2024): Jornal de Investigação Médica; 41–56 ; 2184-7509 ; 10.29073/jim.v5i1

    وصف الملف: application/pdf

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    Academic Journal

    المصدر: Journal of Medical Research (JIM); Vol. 5 No. 1 (2024): Journal of Medical Research; 57–71 ; Jornal de Investigação Médica (JIM); Vol. 5 N.º 1 (2024): Jornal de Investigação Médica; 57–71 ; 2184-7509 ; 10.29073/jim.v5i1

    وصف الملف: application/pdf

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    Book

    المساهمون: Clinicum, HUS Helsinki and Uusimaa Hospital District, Department of Medicine, Porvoo Hospital Area, HUSLAB, HUS Diagnostic Center, Medicum, Department of Medical and Clinical Genetics, Myllymaki_lab, TRIMM - Translational Immunology Research Program, HUS Comprehensive Cancer Center, Department of Oncology, Hematologian yksikkö, Department of Clinical Chemistry and Hematology

    وصف الملف: application/pdf

    Relation: http://hdl.handle.net/10138/564700; 85164230129; 001032976400029

  8. 8

    المساهمون: Repositório Científico do Instituto Politécnico de Santarém

    وصف الملف: application/pdf

    Relation: Pinto M..R. et al. (2022). Innovative Educational Approach in Healthcare-Associated Infection Prevention and Control. Results of a European Study. In: García Alonso J., Fonseca C. (eds) Gerontechnology IV. IWoG 2021. Lecture Notes in Bioengineering. Springer, Cham. https://doi.org/10.1

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    Academic Journal

    Relation: https://doi.org/10.20883/pielpol.2023.8; Patrzała, A., Bączyk G., Basa, A., Jankowiak-Bernaciak. A., Guzmán Ordaz, R., do Rosário Pinto, M., do Sacramento Costa Reis, A.M., Augusto Simões, J., Luisa Torres, A., Silén-Lipponen, M., Korhonen, U., Koponen, L., Myllymäki, M., Picado Valverde, E.M., Yurrebaso Macho, A., Juanes Méndez, J.A., Pérez Iglesias, J.L., L. Ward Mayens, A. L., Mirón-Canelo, J. A., Graveto, J., Pardal, J., Santos-Costa, P., Serambeque, B., Salgueiro-Oliveira & A., Parreira, P. (2023). Healthcare-associated infection prevention and control learning and teaching processes in European higher education institutions-a qualitative study. Polish Nursing, 3(89), 91-101. https://doi.org/10.20883/pielpol.2023.8; http://hdl.handle.net/10366/156034

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    Conference

    المساهمون: van der Aa, Nico

    وصف الملف: application/pdf; fulltext

    Relation: EAEEIE 2023 : 32nd Annual Conference of the European Association for Education in Electrical and Information Engineering; Proceedings of the International Conference on European Association for Education in Electrical and Information Engineering; 979-8-3503-4676-3; Annual Conference of the European Association for Education in Electrical and Information Engineering; S22136; Centre for Economic Development, Transport and the Environment of Central Finland; Keski-Suomen ELY-keskus; Laine, S., Målquist, U., Myllymäki, M., & Hakala, I. (2023). Women in IT Project : Survey Results. In N. van der Aa (Ed.), EAEEIE 2023 : 32nd Annual Conference of the European Association for Education in Electrical and Information Engineering . IEEE. Proceedings of the International Conference on European Association for Education in Electrical and Information Engineering. https://doi.org/10.23919/EAEEIE55804.2023.10181717; CONVID_184054123

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    Conference

    المساهمون: van der Aa, Nico

    وصف الملف: application/pdf; fulltext

    Relation: EAEEIE 2023 : 32nd Annual Conference of the European Association for Education in Electrical and Information Engineering; Proceedings of the International Conference on European Association for Education in Electrical and Information Engineering; 979-8-3503-4676-3; Annual Conference of the European Association for Education in Electrical and Information Engineering; CONVID_184054959

  12. 12
    Conference

    المساهمون: van der Aa, Nico

    وصف الملف: application/pdf; fulltext

    Relation: EAEEIE 2023 : 32nd Annual Conference of the European Association for Education in Electrical and Information Engineering; Proceedings of the International Conference on European Association for Education in Electrical and Information Engineering; 979-8-3503-4676-3; Annual Conference of the European Association for Education in Electrical and Information Engineering; Jolkkonen, T., Nikula, P., Myllymäki, M., & Hakala, I. (2023). Framework for the conversion of RDI project outputs into educational material. In N. van der Aa (Ed.), EAEEIE 2023 : 32nd Annual Conference of the European Association for Education in Electrical and Information Engineering . IEEE. Proceedings of the International Conference on European Association for Education in Electrical and Information Engineering. https://doi.org/10.23919/EAEEIE55804.2023.10182027; CONVID_184032146

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    Conference
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    Academic Journal

    Relation: https://doi.org/10.3390/jpm12020180; Parreira, P., Santos-Costa, P., Pardal, J., Neves, T., Bernardes, R. A., Serambeque, B., Sousa, L. B., Graveto, J., Silén-Lipponen, M., Korhonen, U., Koponen, L., Myllymäki, M., Macho, A. Y., Ward Mayens, A. L., Valverde, E. M. P., Ordaz, R. G., Méndez, J. A. J., Iglesias, J. L. P., Canelo, J. A. M., et al. (2022). Nursing Students’ Perceptions on Healthcare-Associated Infection Control and Prevention Teaching and Learning Experience in Portugal. Journal of Personalized Medicine, 12(2). https://doi.org/10.3390/JPM12020180; http://hdl.handle.net/10366/156161

  15. 15
    Academic Journal

    المساهمون: TRIMM - Translational Immunology Research Program, Medicum, Department of Clinical Chemistry and Hematology, University of Helsinki, HUS Comprehensive Cancer Center, Department of Oncology, Hematologian yksikkö, Faculty Common Matters (Faculty of Medicine), Research Programs Unit, Clinicum, Helsinki University Hospital Area, Myllymaki_lab

    وصف الملف: application/pdf

    Relation: The authors thank Christopher R. Reilly, MD (Dana -Farber Cancer Institute) for contributing to the text and for providing disease-specific expertise. S.L. was supported by University of Helsinki, Biomedicum Helsinki Foundation and Finnish Medical Foundation. M.M. was supported by Sigrid Juselius Foundation, Academy of Finland, and Finnish Medical Foundation.; Lundgren , S , Keränen , M , Wartiovaara-Kautto , U & Myllymäki , M 2022 , ' Somatic compensation of inherited bone marrow failure ' , Seminars in Hematology , vol. 59 , no. 3 , pp. 167-173 . https://doi.org/10.1053/j.seminhematol.2022.07.002; ORCID: /0000-0002-8194-7356/work/121257647; http://hdl.handle.net/10138/349980; 1090b5c2-1ca6-4ce5-819b-fdef5332a12e; 000862292400008

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    Academic Journal

    المساهمون: Department of Clinical Chemistry and Hematology, Medicum, Hematologian yksikkö, HUS Comprehensive Cancer Center, Department of Oncology, HUSLAB, TRIMM - Translational Immunology Research Program, Research Programs Unit, Institute for Molecular Medicine Finland, University of Helsinki, Department of Medical and Clinical Genetics, Digital Precision Cancer Medicine (iCAN)

    وصف الملف: application/pdf

    Relation: Acknowledgements The research was funded by the European Research Council (Project: M-IMM 647355), Academy of Finland Heal-Art consortium (314442) and special COVID funding (335527), ERA PerMed (JAKSTAT-TARGET consortium), Sigrid Juselius Foundation, Signe and Ane Gyllenberg Foundation, Helsinki Institute for Life Science, and Cancer Foundation Finland. R.M. was supported by the Austrian Science Fund (FWF) (SFB-F04707,SFB-F06105, and under the frame of ERA ERA-NET [I 4157-B]). Amplicon sequencing was performed at the Institute for Molecular Medicine Finland FIMM Technology Centre, which is supported by Biocenter Finland. We acknowledge IT Center for Science Ltd for computational resources. Finnish Red Cross Blood Service is acknowledged for providing healthy control samples.; Kim , D , Park , G , Huuhtanen , J , Ghimire , B , Rajala , H , Moriggl , R , Chan , W C , Kankainen , M , Myllymäki , M & Mustjoki , S 2021 , ' STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation ' , Leukemia , vol. 35 , no. 12 , pp. 3430-3443 . https://doi.org/10.1038/s41375-021-01296-0; ORCID: /0000-0002-1253-8946/work/108464793; ORCID: /0000-0002-0816-8241/work/108466651; ORCID: /0000-0002-8194-7356/work/108467253; ORCID: /0000-0001-5076-8366/work/152343061; http://hdl.handle.net/10138/340467; 68b71307-7586-46a5-bb9e-c2cbc639dcde; 000656799500001

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    Academic Journal
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    Academic Journal
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    Conference

    وصف الملف: application/pdf; fulltext

    Relation: FIE 2022 : Proceedings of the IEEE Frontiers in Education Conference; Conference proceedings : Frontiers in Education Conference; Frontiers in Education Conference; CONVID_160501210

  20. 20
    Conference

    المؤلفون: Myllymäki, Mikko, Hakala, Ismo

    وصف الملف: application/pdf; fulltext

    Relation: FIE 2022 : Proceedings of the IEEE Frontiers in Education Conference; Conference proceedings : Frontiers in Education Conference; Frontiers in Education Conference; CONVID_160498821