يعرض 1 - 20 نتائج من 129 نتيجة بحث عن '"MutY"', وقت الاستعلام: 0.68s تنقيح النتائج
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    Academic Journal
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    Academic Journal

    المساهمون: Olivieri, Alessio, Nardi, Alessandro Nicola, D'Abramo, Marco

    مصطلحات موضوعية: MutY, Molecular Dynamic, Redox, DNA, QM/MM

    Relation: info:eu-repo/semantics/altIdentifier/pmid/38990758; info:eu-repo/semantics/altIdentifier/wos/WOS:001279950000001; volume:63; issue:15; firstpage:1991; lastpage:1998; numberofpages:8; journal:BIOCHEMISTRY; https://hdl.handle.net/11573/1721606

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    Academic Journal

    المؤلفون: Iyama, Teruaki, Wilson, David M

    المصدر: DNA Repair. 12(8)

    مصطلحات موضوعية: Genetics, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Cancer, Neurosciences, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Aetiology, Underpinning research, Generic health relevance, Neurological, Animals, DNA, DNA Damage, DNA Repair, Disease Models, Animal, Humans, Neurons, O(6)-Methylguanine-DNA Methyltransferase, Pyrimidine Dimers, 6-4PPs, 8-oxoguanine DNA glycosylase, AOA1, AP, AP endonuclease 1, APE1, APTX, ATM, CPDs, CS, CSR, Cockayne syndrome, DAR, DNA double strand break repair, DNA polymerase β, DNA repair, DNA single strand break repair, DNA single strand breaks, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, DSBR, Dividing and non-dividing, ERCC1, Endogenous DNA damage, FEN1, GG-NER, HNPCC, HR, IR, MAP, MCSZ, MGMT, MMR, MPG, MUTYH, MUTYH-associated polyposis, N-methylpurine-DNA glycosylase, NEIL1, NER, NHEJ, NSC, NTH1, Neural cells, Neurological disorder, O(6)-methylguanine-DNA methyltransferase, OGG1, PARP1, PCNA, PG, PNKP, PUA, Pol β, RFC, RNA polymerase, RNAP, RPA, SCAN1, SCID, SDSA, SSA, SSBR, SSBs, TC-NER, TDP1, TFIIH, TOP1, TTD, Top1 cleavage complex, Top1cc, UNG, X-ray repair cross-complementing protein 1, XP, XRCC1, aprataxin, apurinic/apyrimidinic, ataxia telangiectasia mutated, ataxia with ocular motor apraxia 1, class switch recombination, cyclobutane pyrimidine dimers, dRP, deoxyribose-5-phosphate, endonuclease III-like 1, endonuclease VIII-like 1, excision repair cross complementing 1, flap endonuclease 1, global genome-NER, hereditary nonpolyposis colorectal cancer, homologous recombination, human mutY homolog, ionizing radiation, microcephaly with early-onset, intractable seizures and developmental delay, mismatch repair, neural stem cells, nonhomologous end joining, nucleotide excision repair, phospho-α, β-unsaturated aldehyde, phosphoglycolate, poly(ADP-ribose) polymerase-1, polynucleotide kinase 3′-phosphatase, proliferating cellular nuclear antigen, pyrimidine-(6, 4)-pyrimidone photoproducts., replication factor C, replication protein A, severe combined immunodeficient, single-strand annealing, spinocerebellar ataxia with axonal neuropathy-1, synthesis-dependent strand annealing, topoisomerase 1, transcription domains-associated repair, transcription factor II H, transcription-coupled NER, trichothiodystrophy, tyrosyl-DNA phosphodiesterase 1, uracil-DNA glycosylase, xeroderma pigmentosum, Biochemistry and Cell Biology, Developmental Biology

    وصف الملف: application/pdf

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    Academic Journal

    المصدر: Medical Genetics; Том 19, № 7 (2020); 105-106 ; Медицинская генетика; Том 19, № 7 (2020); 105-106 ; 2073-7998

    وصف الملف: application/pdf

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    Academic Journal

    المساهمون: Universidade Estadual Paulista (UNESP)

    وصف الملف: 459-468

    Relation: International Journal of Biological Macromolecules; http://dx.doi.org/10.1016/j.ijbiomac.2018.12.067; International Journal of Biological Macromolecules, v. 125, p. 459-468.; http://hdl.handle.net/11449/188482; 2-s2.0-85058218499; 9162508978945887; orcid:0000-0003-2460-1145

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    المصدر: Acta Pharmaceutica Sinica. B
    Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)

    مصطلحات موضوعية: Genome instability, PD-L1, programmed death ligand 1, BRCA, breast cancer susceptibility gene, ICI, immune checkpoint inhibitor, medicine.medical_treatment, MUTYH, MutY homolog, cGAS, cyclic GMP–AMP synthase, Review, DNA damage response, Malignant transformation, ORR, objective response rate, PCR, polymerase chain reaction, 0302 clinical medicine, SCNAs, somatic copy number alterations, FDA, United State Food and Drug Administration, Cancer immunotherapy, MGMT, O6-methylguanine methyltransferase, PD-1, RB1, retinoblastoma 1, General Pharmacology, Toxicology and Pharmaceutics, BER, base excision repair, RAD51C, RAD51 homolog C, 0303 health sciences, TME, tumor microenvironment, TP53, tumor protein P53, cGAS–STING, MSI, microsatellite instability, TRIF, Toll-interleukin 1 receptor domain-containing adaptor inducing INF-β, PFS, progression-free survival, STAT, signal transducer and activator of transcription, NEK1, NIMA-related kinase 1, Tumor microenvironment, PALB2, partner and localizer of BRCA2, RSR, replication stress response, 030220 oncology & carcinogenesis, Immunotherapy, PARP, poly-ADP ribose polymerase, JAK, Janus kinase, IHC, immunohistochemistry, Genomic instability, PD-L1, DSBs, double-strand breaks, DNA repair, DNA damage, CHK1, checkpoint kinase 1, IRF1, interferon regulatory factor 1, MLH1, MutL homolog 1, RM1-950, MMR, mismatch repair, STING, stimulator of interferon genes, Biology, MNT, MAX network transcriptional repressor, DDR, DNA damage response, MSH2/6, MutS protein homologue-2/6, OS, overall survival, RPA, replication protein A, 03 medical and health sciences, GSK3β, glycogen synthase kinase 3β, NER, nucleotide excision repair, NSCLC, non-small cell lung cancer, MyD88, myeloid differentiation factor 88, ssDNA, single-stranded DNA, medicine, DAMP, damage-associated molecular patterns, DR, direct repair, 030304 developmental biology, BAP1, BRCA1-associated protein 1, BRAF, v-RAF murine sarcoma viral oncogene homologue B, TLR4, Toll-like receptor 4, Cancer, NGS, next generation sequencing, ATM, ataxia-telangiectasia mutated, NIMA, never-in-mitosis A, medicine.disease, CHEK, cell-cycle checkpoint kinase, PD-1, programmed death 1, MAD1, mitotic arrest deficient-like 1, body regions, IFNγ, interferon gamma, TILs, tumor-infiltrating lymphocytes, TBK1, TANK-binding kinase 1, ATR, ataxia telangiectasia and Rad3 related, Cancer research, NHEJ, nonhomologous end-joining, Therapeutics. Pharmacology, HMGB1, high mobility group box-1, HRR, homologous recombination repair, XRCC4, X-ray repair cross complementing protein 4, TMB, tumor mutational burden

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    Academic Journal

    المساهمون: Couce, A. CSIC, CNB, Madrid, Spain, Alonso-Rodriguez, N. CSIC, CNB, Madrid, Spain, Costas, C. CSIC, CNB, Madrid, Spain, Blazquez, J. CSIC, CNB, Madrid, Spain, Couce, A. INSERM, Unite Mixte Rech 1137, IAME, Paris, France, Alonso-Rodriguez, N. Inst Pasteur, Paris, France, Costas, C. Inst Biomed Sevilla IBIS, Seville, Spain, Blazquez, J. Inst Biomed Sevilla IBIS, Seville, Spain, Oliver, A. Hosp Son Dureta IUNICS, Palma De Mallorca, Spain, Instituto de Salud Carlos III, Plan Nacional de I+D+i, Ministerio de Economia y Competitividad, Spanish Network for Research in Infectious Diseases, European Development Regional Fund A way to achieve Europe ERDF

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