المؤلفون: Murithi, James Muriungi

مصطلحات موضوعية: Parasitology, Antimalarials, Plasmodium falciparum, Malaria, Genomes

المؤلفون: Arendse, Lauren, Murithi, James, Qahash, Tarrick, Pasaje, Charisse, Godoy, Luiz, Dey, Sumanta, Gibhard, Liezl, Ghidelli-Disse, Sonja, Drewes, Gerard, Bantscheff, Marcus, Lafuente-Monasterio, Maria, Fienberg, Stephen, Wambua, Lynn, Gachuhi, Samuel, Coertzen, Dina, van der Watt, Mariëtte, Reader, Janette, Aswat, Ayesha, Erlank, Erica, Venter, Nelius, Mittal, Nimisha, Luth, Madeline, Ottilie, Sabine, Winzeler, Elizabeth, Koekemoer, Lizette, Birkholtz, Lyn-Marie, Niles, Jacquin, Llinás, Manuel, Fidock, David, Chibale, Kelly

المصدر: Science Translational Medicine. 14(667)

مصطلحات موضوعية: Animals, Humans, Antimalarials, Plasmodium falciparum, MTOR Inhibitors, 1-Phosphatidylinositol 4-Kinase, Guanosine Monophosphate, Life Cycle Stages, TOR Serine-Threonine Kinases, Plasmodium, Sirolimus, Mammals

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6kx4p874
https://escholarship.org/content/qt6kx4p874/qt6kx4p874.pdf

المؤلفون: Murithi, James, Deni, Ioanna, Pasaje, Charisse, Okombo, John, Bridgford, Jessica, Gnädig, Nina, Edwards, Rachel, Yeo, Tomas, Mok, Sachel, Burkhard, Anna, Coburn-Flynn, Olivia, Istvan, Eva, Sakata-Kato, Tomoyo, Gomez-Lorenzo, Maria, Cowell, Annie, Wicht, Kathryn, Le Manach, Claire, Kalantarov, Gavreel, Dey, Sumanta, Duffey, Maëlle, Laleu, Benoît, Lukens, Amanda, Ottilie, Sabine, Vanaerschot, Manu, Trakht, Ilya, Gamo, Francisco-Javier, Wirth, Dyann, Goldberg, Daniel, Odom John, Audrey, Chibale, Kelly, Winzeler, Elizabeth, Niles, Jacquin, Fidock, David

المصدر: Cell Chemical Biology. 29(5)

مصطلحات موضوعية: ABCI3, CRISPR/Cas9, Plasmodium falciparum malaria, biphasic dose-response curves, cellular accumulation assays, conditional knockdowns, copy-number variations, heme fractionation, pfcrt, ATP-Binding Cassette Transporters, Animals, Antimalarials, Folic Acid Antagonists, Heme, Malaria, Falciparum, Membrane Transport Proteins, Parasites, Plasmodium falciparum, Protozoan Proteins, Quinolines

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4277b0xk
https://escholarship.org/content/qt4277b0xk/qt4277b0xk.pdf

المؤلفون: Summers, Robert, Pasaje, Charisse, Pisco, Joao, Striepen, Josefine, Luth, Madeline, Kumpornsin, Krittikorn, Carpenter, Emma, Munro, Justin, Lin, De, Plater, Andrew, Punekar, Avinash, Shepherd, Andrew, Shepherd, Sharon, Vanaerschot, Manu, Murithi, James, Rubiano, Kelly, Akidil, Aslı, Ottilie, Sabine, Mittal, Nimisha, Dilmore, A, Won, Madalyn, Mandt, Rebecca, McGowen, Kerry, Owen, Edward, Walpole, Chris, Llinás, Manuel, Lee, Marcus, Fidock, David, Gilbert, Ian, Wirth, Dyann, Niles, Jacquin, Baragaña, Beatriz, Lukens, Amanda, Winzeler, Elizabeth

المصدر: Cell Chemical Biology. 29(2)

مصطلحات موضوعية: Plasmodium falciparum, acetyl-CoA synthetase, antimalarial, drug development, drug target identification, histone acetylation, malaria, mechanism of action, Acetate-CoA Ligase, Antimalarials, Enzyme Inhibitors, Humans, Malaria, Models, Molecular, Molecular Structure, Parasitic Sensitivity Tests, Plasmodium falciparum

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2t51p0mx
https://escholarship.org/content/qt2t51p0mx/qt2t51p0mx.pdf

المؤلفون: Guto Kerubo Carolyne, Njiru Murithi James, Getabu Albert, Gichana Moraa Zipporah

المصدر: Journal of Technology & Socio-Economic Development, 10(1), 187-198, (2023-07-06)

مصطلحات موضوعية: Physico-chemical parameters, Principal component analysis, Spatial temporal variation

Relation: https://zenodo.org/communities/ciris; https://doi.org/10.5281/zenodo.8122276; https://doi.org/10.5281/zenodo.8122277; oai:zenodo.org:8122277

الاتاحة: https://doi.org/10.5281/zenodo.8122277

المؤلفون: Guto Kerubo Carolyne, Njiru Murithi James, Getabu Albert, Gichana Moraa Zipporah

المصدر: Journal of Technology & Socio-Economic Development, 10(1), 210-223, (2023-07-06)

مصطلحات موضوعية: Condition factor, Fullness index, Increased water level, Vacuity index

Relation: https://zenodo.org/communities/ciris; https://doi.org/10.5281/zenodo.8122334; https://doi.org/10.5281/zenodo.8122335; oai:zenodo.org:8122335

الاتاحة: https://doi.org/10.5281/zenodo.8122335

المؤلفون: Guto Kerubo Carolyne, Njiru Murithi James, Getabu Albert, Gichana Moraa Zipporah

المصدر: Journal of Technology & Socio-Economic Development, 10(1), 199-209, (2023-07-06)

مصطلحات موضوعية: Cyclopoidae, Daphnidae, Diversity index, Evenness, Species richness

Relation: https://zenodo.org/communities/ciris; https://doi.org/10.5281/zenodo.8122289; https://doi.org/10.5281/zenodo.8122290; oai:zenodo.org:8122290

الاتاحة: https://doi.org/10.5281/zenodo.8122290

المؤلفون: Cowell, Annie N, Istvan, Eva S, Lukens, Amanda K, Gomez-Lorenzo, Maria G, Vanaerschot, Manu, Sakata-Kato, Tomoyo, Flannery, Erika L, Magistrado, Pamela, Owen, Edward, Abraham, Matthew, LaMonte, Gregory, Painter, Heather J, Williams, Roy M, Franco, Virginia, Linares, Maria, Arriaga, Ignacio, Bopp, Selina, Corey, Victoria C, Gnädig, Nina F, Coburn-Flynn, Olivia, Reimer, Christin, Gupta, Purva, Murithi, James M, Moura, Pedro A, Fuchs, Olivia, Sasaki, Erika, Kim, Sang W, Teng, Christine H, Wang, Lawrence T, Akidil, Aslı, Adjalley, Sophie, Willis, Paul A, Siege, Dionicio, Tanaseichuk, Olga, Zhong, Yang, Zhou, Yingyao, Llinás, Manuel, Ottilie, Sabine, Gamo, Francisco-Javier, Lee, Marcus CS, Goldberg, Daniel E, Fidock, David A, Wirth, Dyann F, Winzeler, Elizabeth A

المصدر: Science. 359(6372)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Clinical Sciences, Biotechnology, Emerging Infectious Diseases, Orphan Drug, Infectious Diseases, Malaria, Rare Diseases, Antimicrobial Resistance, Genetics, Vector-Borne Diseases, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Activation, Metabolic, Alleles, Antimalarials, DNA Copy Number Variations, Directed Molecular Evolution, Drug Resistance, Drug Resistance, Multiple, Genes, Protozoan, Genome, Protozoan, Metabolomics, Mutation, Plasmodium falciparum, Selection, Genetic, Transcription Factors, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/46g806c2
https://escholarship.org/content/qt46g806c2/qt46g806c2.pdf

المؤلفون: Murithi, James, Kamucha, George, Letting, Lawrence

المصدر: 2024 9th International Youth Conference on Energy (IYCE) ; page 1-7

الاتاحة: http://dx.doi.org/10.1109/iyce60333.2024.10634944
http://xplorestaging.ieee.org/ielx8/10634850/10634905/10634944.pdf?arnumber=10634944

المؤلفون: Qiu, Deyun, Pei, Jinxin V., Rosling, James E. O., Thathy, Vandana, Li, Dongdi, Xue, Yi, Tanner, John D., Penington, Jocelyn Sietsma, Aw, Yi Tong Vincent, Aw, Jessica Yi Han, Xu, Guoyue, Tripathi, Abhai K., Gnadig, Nina F., Yeo, Tomas, Fairhurst, Kate J., Stokes, Barbara H., Murithi, James M., Kümpornsin, Krittikorn, Hasemer, Heath, Dennis, Adelaide S. M., Ridgway, Melanie C., Schmitt, Esther K., Straimer, Judith, Papenfuss, Anthony T., Lee, Marcus C. S., Corry, Ben, Sinnis, Photini, Fidock, David A., van Dooren, Giel G., Kirk, Kiaran, Lehane, Adele M.

المصدر: Qiu , D , Pei , J V , Rosling , J E O , Thathy , V , Li , D , Xue , Y , Tanner , J D , Penington , J S , Aw , Y T V , Aw , J Y H , Xu , G , Tripathi , A K , Gnadig , N F , Yeo , T , Fairhurst , K J , Stokes , B H , Murithi , J M , Kümpornsin , K , Hasemer , H , Dennis , A S M , Ridgway , M ....

مصطلحات موضوعية: Malaria, Parasite biology, /dk/atira/pure/subjectarea/asjc/1600/1600, name=General Chemistry, /dk/atira/pure/subjectarea/asjc/1300/1300, name=General Biochemistry,Genetics and Molecular Biology, /dk/atira/pure/subjectarea/asjc/1000, name=General, /dk/atira/pure/subjectarea/asjc/3100/3100, name=General Physics and Astronomy

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/15432e7c-3143-4b78-aecb-aeeb6f0dc78e
https://doi.org/10.1038/s41467-022-33403-9
https://discovery.dundee.ac.uk/ws/files/104341266/s41467_022_33403_9.pdf
http://www.scopus.com/inward/record.url?scp=85139536114&partnerID=8YFLogxK

المؤلفون: Summers, Robert L., Pasaje, Charisse Flerida A., Pisco, Joao P., Striepen, Josefine, Luth, Madeline R., Kumpornsin, Krittikorn, Carpenter, Emma F., Munro, Justin T., Lin, De, Plater, Andrew, Punekar, Avinash S., Shepherd, Andrew M., Shepherd, Sharon M., Vanaerschot, Manu, Murithi, James M., Rubiano, Kelly, Akidil, Aslı, Ottilie, Sabine, Mittal, Nimisha, Dilmore, A. Hazel, Won, Madalyn, Mandt, Rebecca E. K., McGowen, Kerry, Owen, Edward, Walpole, Chris, Llinás, Manuel, Lee, Marcus C. S., Winzeler, Elizabeth A., Fidock, David A., Gilbert, Ian H., Wirth, Dyann F., Niles, Jacquin C., Baragaña, Beatriz, Lukens, Amanda K.

المصدر: Summers , R L , Pasaje , C F A , Pisco , J P , Striepen , J , Luth , M R , Kumpornsin , K , Carpenter , E F , Munro , J T , Lin , D , Plater , A , Punekar , A S , Shepherd , A M , Shepherd , S M , Vanaerschot , M , Murithi , J M , Rubiano , K , Akidil , A , Ottilie , S , Mittal , N , Dilmore , A H , Won , M , Mandt , R ....

مصطلحات موضوعية: malaria, drug target identification, antimalarial, drug development, acetyl-CoA synthetase, Plasmodium falciparum, mechanism of action, histone acetylation, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/a79f3004-0a50-4219-95f6-445e1d5cd4a4
https://doi.org/10.1016/j.chembiol.2021.07.010
https://discovery.dundee.ac.uk/ws/files/65647009/PIIS2451945621003500.pdf
http://www.scopus.com/inward/record.url?scp=85116027729&partnerID=8YFLogxK

المؤلفون: Miguel-Blanco, Celia, Murithi, James M., Benavente, Ernest Diez, Angrisano, Fiona, Sala, Katarzyna A., van Schalkwyk, Donelly A., Vanaerschot, Manu, Schwach, Frank, Fuchter, Matthew J., Billker, Oliver, Sutherland, Colin J., Campino, Susana G., Clark, Taane G., Blagborough, Andrew M., Fidock, David A., Herreros, Esperanza, Gamo, Francisco Javier, Baum, Jake, Delves, Michael J.

المصدر: Scientific Reports. 11(1)

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-180515
https://doi.org/10.1038/s41598-021-81343-z
https://umu.diva-portal.org/smash/get/diva2:1531324/FULLTEXT01.pdf

المؤلفون: Vanaerschot, Manu, Murithi, James M., Pasaje, Charisse Flerida A., Ghidelli-Disse, Sonja, Dwomoh, Louis, Bird, Megan, Spottiswoode, Natasha, Mittal, Nimisha, Arendse, Lauren B., Owen, Edward S., Wicht, Kathryn J., Siciliano, Giulia, Bösche, Markus, Yeo, Tomas, Kumar, T. R. Santha, Mok, Sachel, Carpenter, Emma F., Giddins, Marla J., Sanz, Olalla, Ottilie, Sabine, Alano, Pietro, Chibale, Kelly, Llinás, Manuel, Uhlemann, Anne Catrin, Delves, Michael, Tobin, Andrew B., Doerig, Christian, Winzeler, Elizabeth A., Lee, Marcus C.S., Niles, Jacquin C., Fidock, David A.

المصدر: Vanaerschot , M , Murithi , J M , Pasaje , C F A , Ghidelli-Disse , S , Dwomoh , L , Bird , M , Spottiswoode , N , Mittal , N , Arendse , L B , Owen , E S , Wicht , K J , Siciliano , G , Bösche , M , Yeo , T , Kumar , T R S , Mok , S , Carpenter , E F , Giddins , M J , Sanz , O , Ottilie , S , Alano , P , Chibale , K , Llinás ....

مصطلحات موضوعية: cGMP-dependent protein kinase (PKG), chemoproteomics, conditional knockdown, kinase, malaria drug discovery, phosphoproteomics, Plasmodium falciparum, resistance, target identification, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/bb93ec18-7d46-4312-8729-97d5c19cb502
https://doi.org/10.1016/j.chembiol.2020.04.001
https://discovery.dundee.ac.uk/ws/files/104657588/PIIS245194562030115X.pdf
http://www.scopus.com/inward/record.url?scp=85087768957&partnerID=8YFLogxK

المؤلفون: Murithi, James M., Owen, Edward S., Istvan, Eva S., Lee, Marcus C.S., Ottilie, Sabine, Chibale, Kelly, Goldberg, Daniel E., Winzeler, Elizabeth A., Llinás, Manuel, Fidock, David A., Vanaerschot, Manu

المصدر: Murithi , J M , Owen , E S , Istvan , E S , Lee , M C S , Ottilie , S , Chibale , K , Goldberg , D E , Winzeler , E A , Llinás , M , Fidock , D A & Vanaerschot , M 2020 , ' Combining Stage Specificity and Metabolomic Profiling to Advance Antimalarial Drug Discovery ' , Cell Chemical Biology , vol. 27 , no. 2 , pp. 158-171.e3 . https://doi.org/10.1016/j.chembiol.2019.11.009

مصطلحات موضوعية: asexual blood stages, drug resistance, hemoglobin catabolism, malaria, metabolomics, mitochondria, mode of action, Plasmodium falciparum, target identification, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine, /dk/atira/pure/subjectarea/asjc/1300/1312, name=Molecular Biology, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/1300/1308, name=Clinical Biochemistry

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/814a9547-0493-45a2-b391-4596ae0e35fa
https://doi.org/10.1016/j.chembiol.2019.11.009
https://discovery.dundee.ac.uk/ws/files/104721039/1_s2.0_S2451945619303915_main.pdf
http://www.scopus.com/inward/record.url?scp=85079341308&partnerID=8YFLogxK

المؤلفون: Blackman, Michael J., Stokes, Barbara H., Yoo, Euna, Murithi, James M., Luth, Madeline R., Afanasyev, Pavel, da Fonseca, Paula C.A., Winzeler, Elizabeth A., Ng, Caroline L., Bogyo, Matthew, Fidock, David A.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/212665/1/212665.pdf; Blackman, M. J. et al. (2019) Covalent Plasmodium falciparum-selective proteasome inhibitors exhibit a low propensity for generating resistance in vitro and synergize with multiple antimalarial agents. PLoS Pathogens , 15(6), e1007722. (doi:10.1371/journal.ppat.1007722 ) (PMID:31170268) (PMCID:PMC6553790)

الاتاحة: https://eprints.gla.ac.uk/212665/
https://eprints.gla.ac.uk/212665/1/212665.pdf

المؤلفون: Stokes, Barbara H., Yoo, Euna, Murithi, James M., Luth, Madeline R., Afanasyev, Pavel, da Fonseca, Paula C. A., Winzeler, Elizabeth A., Ng, Caroline L., Bogyo, Matthew, Fidock, David A.

المساهمون: Blackman, Michael J., National Institute of Allergy and Infectious Diseases, Medical Research Council

المصدر: PLOS Pathogens ; volume 15, issue 6, page e1007722 ; ISSN 1553-7374

الاتاحة: http://dx.doi.org/10.1371/journal.ppat.1007722
http://dx.plos.org/10.1371/journal.ppat.1007722

المؤلفون: Guto, Kerubo Carolyne, Njiru, Murithi James, Getabu, Albert, Gichana, Moraa Zipporah

المصدر: Journal of Technology & Socio-Economic Development, 12(1), 15-29, (2023-10-22)

Relation: https://zenodo.org/communities/ciris; https://doi.org/10.5281/zenodo.10031966; https://doi.org/10.5281/zenodo.10031967; oai:zenodo.org:10031967

الاتاحة: https://doi.org/10.5281/zenodo.10031967

المؤلفون: Guto, Kerubo Carolyne, Njiru, Murithi James, Getabu, Albert, Gichana, Moraa Zipporah

المصدر: Journal of Technology & Socio-Economic Development, 12(1), 30-49, (2023-11-27)

مصطلحات موضوعية: estuary, Rainfall, phytoplankton

Relation: https://zenodo.org/communities/ciris; https://doi.org/10.5281/zenodo.10208081; https://doi.org/10.5281/zenodo.10208082; oai:zenodo.org:10208082

الاتاحة: https://doi.org/10.5281/zenodo.10208082

المؤلفون: Cowell, Annie N., Istvan, Eva S., Lukens, Amanda K., Gomez-Lorenzo, Maria G., Vanaerschot, Manu, Sakata-Kato, Tomoyo, Flannery, Erika L., Magistrado, Pamela, Owen, Edward, Abraham, Matthew, LaMonte, Gregory, Painter, Heather J., Williams, Roy M., Franco, Virginia, Linares, Maria, Arriaga, Ignacio, Bopp, Selina, Corey, Victoria C., Gnädig, Nina F., Coburn-Flynn, Olivia, Reimer, Christin, Gupta, Purva, Murithi, James M., Moura, Pedro A., Fuchs, Olivia, Sasaki, Erika, Kim, Sang W., Teng, Christine H., Wang, Lawrence T., Akidil, Asl, Adjalley, Sophie, Willis, Paul A., Siegel, Dionicio, Tanaseichuk, Olga, Zhong, Yang, Zhou, Yingyao, Llinás, Manuel, Ottilie, Sabine, Gamo, Francisco Javier, Lee, Marcus C.S., Goldberg, Daniel E., Fidock, David A., Wirth, Dyann F., Winzeler, Elizabeth A.

المصدر: Cowell , A N , Istvan , E S , Lukens , A K , Gomez-Lorenzo , M G , Vanaerschot , M , Sakata-Kato , T , Flannery , E L , Magistrado , P , Owen , E , Abraham , M , LaMonte , G , Painter , H J , Williams , R M , Franco , V , Linares , M , Arriaga , I , Bopp , S , Corey , V C , Gnädig , N F , Coburn-Flynn , O , Reimer , C , Gupta , P , Murithi , ....

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/1000, name=General

وصف الملف: application/pdf

الاتاحة: https://discovery.dundee.ac.uk/en/publications/c7c2e86f-97d2-46f4-9ee4-7f87beb886ba
https://doi.org/10.1126/science.aan4472
https://discovery.dundee.ac.uk/ws/files/105050826/science.aan4472.pdf
http://www.scopus.com/inward/record.url?scp=85040443759&partnerID=8YFLogxK

المؤلفون: Ash, Peter E. A., Stanford, Elizabeth A., Al Abdulatif, Ali, Ramirez-Cardenas, Alejandra, Ballance, Heather I., Boudeau, Samantha, Jeh, Amanda, Murithi, James M., Tripodis, Yorghos, Murphy, George J., Sherr, David H., Wolozin, Benjamin

المساهمون: National Institute of Environmental Health Sciences, National Institute of Neurological Disorders and Stroke, National Institute on Aging, Alzheimer's Association, BrightFocus Foundation, CureAlzheimer Foundation

المصدر: Molecular Neurodegeneration ; volume 12, issue 1 ; ISSN 1750-1326

الاتاحة: http://dx.doi.org/10.1186/s13024-017-0177-9
http://link.springer.com/content/pdf/10.1186/s13024-017-0177-9.pdf
http://link.springer.com/article/10.1186/s13024-017-0177-9/fulltext.html