المؤلفون: Mouchlis, Varnavas D, Dennis, Edward A

المصدر: Accounts of Chemical Research. 55(23)

مصطلحات موضوعية: Generic health relevance, Cholesterol Esters, Phospholipases A2, Phospholipids, Phospholipases, Lipoproteins, Triglycerides, Water, Polyesters, Substrate Specificity, Chemical Sciences, General Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2564d3sc
https://escholarship.org/content/qt2564d3sc/qt2564d3sc.pdf

المؤلفون: Mouchlis, Varnavas D, Hayashi, Daiki, Vasquez, Alexis M, Cao, Jian, McCammon, J Andrew, Dennis, Edward A

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(2)

مصطلحات موضوعية: Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences, 1-Alkyl-2-acetylglycerophosphocholine Esterase, Allosteric Regulation, Binding Sites, Catalysis, Catalytic Domain, Fatty Acids, Humans, Hydrolysis, Lipoproteins, HDL, Membranes, Molecular Dynamics Simulation, Phospholipids, Substrate Specificity, phospholipase, lipoprotein, allosterism, membrane, lipid

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3s72j2hd
https://escholarship.org/content/qt3s72j2hd/qt3s72j2hd.pdf

المؤلفون: Hayashi, Daiki, Mouchlis, Varnavas D, Dennis, Edward A

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1867(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Calcium, Cell Membrane, Cytosol, Glycerophospholipids, Humans, Hydrolysis, Kinetics, Phospholipases A2, Phospholipid Ethers, Phospholipids, Substrate Specificity, Vinyl Compounds, Phospholipase A(2), Ether phospholipids, Plasmalogens, Lipidomics, Molecular dynamics simulation, Medical and Health Sciences, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/72f0q3r6

المؤلفون: Hayashi, Daiki, Mouchlis, Varnavas D, Dennis, Edward A

مصطلحات موضوعية: AA, DHA, EPA, arachidonic acid, fatty acid, glycerophospholipid, omega-3, omega-6, phospholipase A2, substrate specificity, Nutrition, Complementary and Integrative Health, Biochemistry & Molecular Biology, Biochemistry and Cell Biology, Medical Biochemistry and Metabolomics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5s0076tp

المؤلفون: Mouchlis, Varnavas D, Mu, Carol, Hammons, Renee, Dennis, Edward A

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Biotechnology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Binding Sites, Fatty Acids, Nonesterified, High-Throughput Screening Assays, Lipidomics, Lysophospholipids, Molecular Docking Simulation, Molecular Dynamics Simulation, Phospholipase A2 Inhibitors, Phospholipases A2, Protein Binding, Protein Interaction Domains and Motifs, Protein Structure, Secondary, Small Molecule Libraries, Substrate Specificity, User-Computer Interface, Dose-response inhibition, Enzymatic assays, Hit compounds, Phospholipase A(2), Virtual screening, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2bj1r8h1

المؤلفون: Hayashi, Daiki, Mouchlis, Varnavas D, Dennis, Edward A

المصدر: The FASEB Journal. 34(S1)

مصطلحات موضوعية: Nutrition, Biochemistry and Cell Biology, Physiology, Medical Physiology, Biochemistry & Molecular Biology

URL الوصول: https://escholarship.org/uc/item/5qt1p3gw

المؤلفون: Koutoulogenis, Giorgos S, Kokotou, Maroula G, Hayashi, Daiki, Mouchlis, Varnavas D, Dennis, Edward A, Kokotos, George

المصدر: Biomolecules. 10(3)

مصطلحات موضوعية: inhibitor, metabolic stability, oxoesters, phospholipase A2, α-methylation, alpha-methylation, phospholipase A(2), Biochemistry and Cell Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5x414355

المؤلفون: Psarra, Anastasia, Kokotou, Maroula G, Galiatsatou, Gerasimia, Mouchlis, Varnavas D, Dennis, Edward A, Kokotos, George

المصدر: ACS Omega. 4(6)

مصطلحات موضوعية: Chemical Engineering, Materials Engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/38s6m4d3

المؤلفون: Mouchlis, Varnavas D, Dennis, Edward A

المصدر: Biochimica et biophysica acta. Molecular and cell biology of lipids. 1864(6)

مصطلحات موضوعية: Humans, Arachidonic Acid, Substrate Specificity, Catalysis, Lipid Metabolism, Phospholipases A2, Lipidomics, Catalytic mechanism, HD-XMS, LC/MS assays, Molecular dynamics, Phospholipase, Substrate specificity, Biological Sciences, Medical and Health Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5hd2t522

المؤلفون: Dedaki, Christina, Kokotou, Maroula G, Mouchlis, Varnavas D, Limnios, Dimitris, Lei, Xiaoyong, Mu, Carol T, Ramanadham, Sasanka, Magrioti, Victoria, Dennis, Edward A, Kokotos, George

المصدر: Journal of Medicinal Chemistry. 62(6)

مصطلحات موضوعية: Diabetes, Autoimmune Disease, Metabolic and endocrine, Animals, Apoptosis, Cytokines, Drug Design, Humans, Inflammation Mediators, Insulin-Secreting Cells, Lactones, Phospholipase A2 Inhibitors, Phospholipases A2, Calcium-Independent, Structure-Activity Relationship, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7j3587tq

المؤلفون: Mouchlis, Varnavas D, Armando, Aaron, Dennis, Edward A

المصدر: Journal of Medicinal Chemistry. 62(4)

مصطلحات موضوعية: Acetates, Catalytic Domain, Enzyme Assays, Group VI Phospholipases A2, Humans, Indoles, Keto Acids, Lipidomics, Membranes, Artificial, Micelles, Molecular Dynamics Simulation, Phospholipase A2 Inhibitors, Phospholipids, Pyrrolidines, Medicinal and Biomolecular Chemistry, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0v686469

المؤلفون: Psarra, Anastasia, Kokotou, Maroula G, Galiatsatou, Gerasimia, Mouchlis, Varnavas D, Dennis, Edward A, Kokotos, George

المصدر: ACS Omega. 3(8)

مصطلحات موضوعية: Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Chemical Engineering, Materials Engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0m74j3gq

المؤلفون: Mouchlis, Varnavas D, McCammon, J Andrew, Dennis, Edward A

المصدر: FASEB JOURNAL. 32(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Physiology, Medical Physiology, Biochemistry & Molecular Biology

URL الوصول: https://escholarship.org/uc/item/09r6x226

المؤلفون: Mouchlis, Varnavas D, Chen, Yuan, McCammon, J Andrew, Dennis, Edward A

المصدر: Journal of the American Chemical Society. 140(9)

مصطلحات موضوعية: Chemical Sciences, Generic health relevance, Binding Sites, Catalytic Domain, Humans, Hydrolysis, Hydrophobic and Hydrophilic Interactions, Molecular Dynamics Simulation, Phospholipases A2, Calcium-Independent, Phospholipases A2, Cytosolic, Phospholipases A2, Secretory, Phospholipids, Substrate Specificity, General Chemistry, Chemical sciences, Engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/19n715vb
https://escholarship.org/content/qt19n715vb/qt19n715vb.pdf

المؤلفون: Mouchlis, Varnavas D, McCammon, J Andrew, Dennis, Edward A

المصدر: BIOPHYSICAL JOURNAL. 114(3)

مصطلحات موضوعية: Biophysics, Physical Sciences, Chemical Sciences, Biological Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/12r122kp

المؤلفون: Mouchlis, Varnavas D, McCammon, J Andrew, Dennis, Edward A

المصدر: BIOPHYSICAL JOURNAL. 114(3)

مصطلحات موضوعية: Biophysics, Physical Sciences, Chemical Sciences, Biological Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/60h2q3x6

المؤلفون: Vasquez, Alexis M, Mouchlis, Varnavas D, Dennis, Edward A

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance, Cell Membrane, Deuterium Exchange Measurement, Humans, Mass Spectrometry, Molecular Dynamics Simulation, Phospholipases A2, Phospholipids, Biochemistry & Molecular Biology, Biochemistry and cell biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/768352qj

المؤلفون: Kokotou, Maroula G, Galiatsatou, Gerasimia, Magrioti, Victoria, Koutoulogenis, Giorgos, Barbayianni, Efrosini, Limnios, Dimitris, Mouchlis, Varnavas D, Satpathy, Banita, Navratil, Aaron, Dennis, Edward A, Kokotos, George

المصدر: Scientific reports. 7(1)

مصطلحات موضوعية: Macrophages, Animals, Mice, Esters, Anti-Inflammatory Agents, Inflammation Mediators, Enzyme Inhibitors, Group IV Phospholipases A2, Molecular Docking Simulation, RAW 264.7 Cells

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7ft8s6xx

المؤلفون: Mouchlis, Varnavas D.^1,2 vmouchlis@gmail.com, Yuan-Hao Hsu^1,2, Daiki Hayashi^1,2,3, Jian Cao^1,2, Sheng Li⁴, McCammon, J. Andrew^1,2 jmccammon@ucsd.edu, Dennis, Edward A.^1,2 edennis@ucsd.edu

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 11/26/2024, Vol. 121 Issue 48, p1-8. 20p.

مصطلحات موضوعية: *PHOSPHOLIPASE A2, *PEPTIDES, *DRUG discovery, *ALLOSTERIC regulation, *MOLECULAR dynamics

المؤلفون: Smyrniotou, Anneta, Kokotou, Maroula G, Mouchlis, Varnavas D, Barbayianni, Efrosini, Kokotos, George, Dennis, Edward A, Constantinou-Kokotou, Violetta

المصدر: Bioorganic & Medicinal Chemistry. 25(3)

مصطلحات موضوعية: Medicinal and Biomolecular Chemistry, Chemical Sciences, Dipeptides, Dose-Response Relationship, Drug, Humans, Molecular Structure, Phospholipase A2 Inhibitors, Phospholipases A2, Calcium-Independent, Pyridines, Structure-Activity Relationship, Inhibitors, Oxoamides, Phospholipase A(2), Pseudodipeptides, Organic Chemistry, Pharmacology and Pharmaceutical Sciences, Medicinal & Biomolecular Chemistry, Biochemistry and cell biology, Medicinal and biomolecular chemistry, Organic chemistry

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/92k42620