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1Academic Journal
المؤلفون: Damba, Turtushikh, Zhang, Mengfan, Serna Salas, Sandra A, Wu, Zongmei, van Goor, Harry, Arenas, Aaron Fierro, Muñoz-Ortega, Martin Humberto, Ventura-Juárez, Javier, Buist-Homan, Manon, Moshage, Han
المصدر: Damba , T , Zhang , M , Serna Salas , S A , Wu , Z , van Goor , H , Arenas , A F , Muñoz-Ortega , M H , Ventura-Juárez , J , Buist-Homan , M & Moshage , H 2024 , ' Inhibition of endogenous hydrogen sulfide production reduces activation of hepatic stellate cells via the induction of cellular senescence ' , Cell Cycle , vol. 23 , no. 6 , pp. 629–644 . https://doi.org/10.1080/15384101.2024.2345477
مصطلحات موضوعية: cellular senescence, cystathionine γ-lyase, hepatic stellate cells, Hydrogen sulfide, liver fibrosis, TGFβ1
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/275bae18-0447-483c-9fce-8824555b61cd
https://research.rug.nl/en/publications/275bae18-0447-483c-9fce-8824555b61cd
https://doi.org/10.1080/15384101.2024.2345477
https://pure.rug.nl/ws/files/1139515841/Inhibition_of_endogenous_hydrogen_sulfide_production_reduces_activation_of_hepatic_stellate_cells_via_the_induction_of_cellular_senescence.pdf
http://www.scopus.com/inward/record.url?scp=85195183608&partnerID=8YFLogxK -
2Academic Journal
المؤلفون: Trillos-Almanza, Maria Camila, Aguilar, Magnolia Martinez, Buist-Homan, Manon, Bomer, Nils, Gomez, Karla Arevalo, de Meijer, Vincent E, van Vilsteren, Frederike G I, Blokzijl, Hans, Moshage, Han
المصدر: Trillos-Almanza , M C , Aguilar , M M , Buist-Homan , M , Bomer , N , Gomez , K A , de Meijer , V E , van Vilsteren , F G I , Blokzijl , H & Moshage , H 2024 , ' Branched-chain amino acids and their metabolites decrease human and rat hepatic stellate cell activation ' , Molecular Biology Reports , vol. 51 , 1116 . https://doi.org/10.1007/s11033-024-10027-4
مصطلحات موضوعية: Humans, Amino Acids, Branched-Chain/metabolism, Animals, Hepatic Stellate Cells/metabolism, Rats, Liver Cirrhosis/metabolism, Cell Proliferation/drug effects, Male, Liver/metabolism, Leucine/pharmacology, Keto Acids/metabolism, End Stage Liver Disease/metabolism, Cells, Cultured
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/a10c24c9-a124-425f-8d2e-94bce478323c
https://research.rug.nl/en/publications/a10c24c9-a124-425f-8d2e-94bce478323c
https://doi.org/10.1007/s11033-024-10027-4
https://pure.rug.nl/ws/files/1144386276/s11033-024-10027-4.pdf
http://www.scopus.com/inward/record.url?scp=85208473339&partnerID=8YFLogxK -
3Academic Journal
المؤلفون: Wu, Zongmei, Xia, Mengmeng, Wang, Junyu, Aguilar, Magnolia Martinez, Buist-Homan, Manon, Moshage, Han
المصدر: Wu , Z , Xia , M , Wang , J , Aguilar , M M , Buist-Homan , M & Moshage , H 2024 , ' Extracellular vesicles originating from steatotic hepatocytes promote hepatic stellate cell senescence via AKT/mTOR signaling ' , Cell Biochemistry and Function , vol. 42 , no. 4 , e4077 . https://doi.org/10.1002/cbf.4077
مصطلحات موضوعية: Animals, Extracellular Vesicles/metabolism, Hepatic Stellate Cells/metabolism, Rats, Proto-Oncogene Proteins c-akt/metabolism, Cellular Senescence/drug effects, TOR Serine-Threonine Kinases/metabolism, Hepatocytes/metabolism, Signal Transduction, Male, Fatty Liver/metabolism, Reactive Oxygen Species/metabolism, Cells, Cultured, Sprague-Dawley
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/6bfb1403-fcf1-4477-b768-c700fcf71131
https://research.rug.nl/en/publications/6bfb1403-fcf1-4477-b768-c700fcf71131
https://doi.org/10.1002/cbf.4077
https://pure.rug.nl/ws/files/1036550291/Cell_Biochemistry_Function_-_2024_-_Wu_-_Extracellular_vesicles_originating_from_steatotic_hepatocytes_promote_hepatic.pdf -
4Academic Journal
المؤلفون: Trillos-Almanza, Maria Camila, Chvatal-Medina, Mateo, Connelly, Margery A., Moshage, Han, Bakker, Stephan J.L., de Meijer, Vincent E., Blokzijl, Hans, Dullaart, Robin P.F.
المصدر: TransplantLines Investigators , Trillos-Almanza , M C , Chvatal-Medina , M , Connelly , M A , Moshage , H , Bakker , S J L , de Meijer , V E , Blokzijl , H & Dullaart , R P F 2024 , ' Circulating Trimethylamine-N-Oxide Is Elevated in Liver Transplant Recipients ' , International Journal of Molecular Sciences , vol. 25 , no. 11 , 6031 . https://doi.org/10.3390/ijms25116031
مصطلحات موضوعية: liver transplantation, microbiota, NMR spectroscopy, Prevention of REnal and Vascular ENd-stage Disease (PREVEND) cohort study, TransplantLines cohort and biobank study, trimethylamine-N-oxide
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/8835fa3b-34af-40ed-8a69-56b89edc208c
https://research.rug.nl/en/publications/8835fa3b-34af-40ed-8a69-56b89edc208c
https://doi.org/10.3390/ijms25116031
https://pure.rug.nl/ws/files/1036552829/ijms-25-06031-v2.pdf
http://www.scopus.com/inward/record.url?scp=85195926585&partnerID=8YFLogxK -
5Academic Journal
المؤلفون: Wang, Junyu, Wu, Zongmei, Xia, Mengmeng, Salas, Sandra Serna, Ospina, Johanna Arroyave, Buist-Homan, Manon, Harmsen, Martin C, Moshage, Han
المصدر: Wang , J , Wu , Z , Xia , M , Salas , S S , Ospina , J A , Buist-Homan , M , Harmsen , M C & Moshage , H 2024 , ' Extracellular vesicles derived from liver sinusoidal endothelial cells inhibit the activation of hepatic stellate cells and Kupffer cells in vitro ' , Biochimica et biophysica acta-Molecular basis of disease , vol. 1870 , no. 3 , 167020 . https://doi.org/10.1016/j.bbadis.2024.167020
وصف الملف: application/pdf
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6Academic Journal
المؤلفون: Hernández Villanueva, Alejandra Andrea, Arab Verdugo, Juan Pablo, Reyes, Daniela, Lapitz, Ainhoa, Moshage, Han, Bañales, Jesús M., Arrese, Marco
مصطلحات موضوعية: Nonalcoholic fatty liver disease, Fatty liver, Alcoholic liver disease, Extracellular vesicles, Signaling, Exosomes, Biomarkers
وصف الملف: 14 páginas; application/pdf
Relation: https://repositorio.uc.cl/handle/11534/87109; WOS:000535559500028
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7Academic Journal
المؤلفون: Wang, Junyu, Zhao, Fenghua, Brouwer, Linda A, Buist-Homan, Manon, Wolters, Justina C, Moshage, Han, Harmsen, Martin C
المصدر: Wang , J , Zhao , F , Brouwer , L A , Buist-Homan , M , Wolters , J C , Moshage , H & Harmsen , M C 2024 , ' Collagen-rich liver-derived extracellular matrix hydrogels augment survival and function of primary rat liver sinusoidal endothelial cells and hepatocytes ' , International Journal of Biological Macromolecules , vol. 278 , 134717 . https://doi.org/10.1016/j.ijbiomac.2024.134717
مصطلحات موضوعية: Biological/mechanical/microarchitectural properties, Extracellular matrix, Liver sinusoidal endothelial cells, Metabolic dysfunction-associated steatotic liver disease
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/a2158da5-2e59-46f0-ae43-73523b42480e
https://research.rug.nl/en/publications/a2158da5-2e59-46f0-ae43-73523b42480e
https://doi.org/10.1016/j.ijbiomac.2024.134717
https://pure.rug.nl/ws/files/1079358652/1-s2.0-S0141813024055223-main.pdf
http://www.scopus.com/inward/record.url?scp=85201423028&partnerID=8YFLogxK -
8Academic Journal
المؤلفون: Li, Yakun, Chvatal-Medina, Mateo, Trillos-Almanza, Maria Camila, Connelly, Margery A., Moshage, Han, Bakker, Stephan J. L., de Meijer, Vincent E., Blokzijl, Hans, Dullaart, Robin P. F.
المصدر: International Journal of Molecular Sciences; Jan2025, Vol. 26 Issue 2, p459, 16p
مصطلحات موضوعية: C-reactive protein, CIRRHOSIS of the liver, LIVER transplantation, MORTALITY, LIVER diseases
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9Academic Journal
المؤلفون: Li, Yakun, Chvatal-Medina, Mateo, Trillos-Almanza, Maria Camila, Bourgonje, Arno R., Connelly, Margery A., Moshage, Han, Bakker, Stephan J. L., de Meijer, Vincent E., Blokzijl, Hans, Dullaart, Robin P. F.
المصدر: International Journal of Molecular Sciences; Dec2024, Vol. 25 Issue 23, p12806, 14p
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10Academic Journal
المؤلفون: Xia, Mengmeng, Wu, Zongmei, Wang, Junyu, Buist-Homan, Manon, Moshage, Han
المصدر: Xia , M , Wu , Z , Wang , J , Buist-Homan , M & Moshage , H 2023 , ' The Coumarin-Derivative Esculetin Protects against Lipotoxicity in Primary Rat Hepatocytes via Attenuating JNK-Mediated Oxidative Stress and Attenuates Free Fatty Acid-Induced Lipid Accumulation ' , Antioxidants (Basel, Switzerland) , vol. 12 , no. 11 , 1922 . https://doi.org/10.3390/antiox12111922
مصطلحات موضوعية: AMP-activated protein kinase, C-Jun N terminal kinase, esculetin, fatty acids, lipid accumulation, lipid droplet, lipotoxicity, metabolic dysfunction associated fatty liver disease, oxidative stress, reactive oxygen species
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/41db15ba-3ab3-43ce-9b1c-c210dd1250e4
https://research.rug.nl/en/publications/41db15ba-3ab3-43ce-9b1c-c210dd1250e4
https://doi.org/10.3390/antiox12111922
https://pure.rug.nl/ws/files/845373047/antioxidants-12-01922-v2_1_.pdf
http://www.scopus.com/inward/record.url?scp=85178320822&partnerID=8YFLogxK -
11Academic Journal
المؤلفون: Geng, Yana, Wang, Junyu, Serna-Salas, Sandra Alejandra, Villanueva, Alejandra Hernández, Buist-Homan, Manon, Arrese, Marco, Olinga, Peter, Blokzijl, Hans, Moshage, Han
المصدر: Geng , Y , Wang , J , Serna-Salas , S A , Villanueva , A H , Buist-Homan , M , Arrese , M , Olinga , P , Blokzijl , H & Moshage , H 2023 , ' Hepatic stellate cells induce an inflammatory phenotype in Kupffer cells via the release of extracellular vesicles ' , Journal of Cellular Physiology , vol. 238 , no. 10 , pp. 2293-2303 . https://doi.org/10.1002/jcp.31086
مصطلحات موضوعية: extracellular vesicles, hepatic stellate cells, inflammation, Kupffer cells, toll-like receptor 4
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/1b3e90e9-c488-41fc-873b-f55078f3a8f9
https://research.rug.nl/en/publications/1b3e90e9-c488-41fc-873b-f55078f3a8f9
https://doi.org/10.1002/jcp.31086
https://pure.rug.nl/ws/files/825335555/Journal_Cellular_Physiology_-_2023_-_Geng_-_Hepatic_stellate_cells_induce_an_inflammatory_phenotype_in_Kupffer_cells_via.pdf -
12Academic Journal
المؤلفون: Geng, Yana, Arroyave-Ospina, Johanna C., Buist-Homan, Manon, Plantinga, Josée, Olinga, Peter, Reijngoud, Dirk Jan, Van Vilsteren, Frederike G.I., Blokzijl, Hans, Kamps, Jan A.A.M., Moshage, Han
المصدر: Geng , Y , Arroyave-Ospina , J C , Buist-Homan , M , Plantinga , J , Olinga , P , Reijngoud , D J , Van Vilsteren , F G I , Blokzijl , H , Kamps , J A A M & Moshage , H 2023 , ' Differential effects of oleate on vascular endothelial and liver sinusoidal endothelial cells reveal its toxic features in vitro ' , Journal of Nutritional Biochemistry , vol. 114 , 109255 . https://doi.org/10.1016/j.jnutbio.2022.109255
مصطلحات موضوعية: Fatty acids, Human umbilical vein endothelial cells, Lipotoxicity, Liver sinusoidal endothelial cells, Mitochondrial function, Triglycerides
وصف الملف: application/pdf
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13Academic Journal
المؤلفون: Villa-Jaimes, Gloria Stephanie, Moshage, Han, Avelar-González, Francisco Javier, González-Ponce, Herson Antonio, Buist-Homan, Manon, Guevara-Lara, Fidel, Sánchez-Alemán, Esperanza, Martínez-Hernández, Sandra Luz, Ventura-Juárez, Javier, Muñoz-Ortega, Martín Humberto, Martínez-Saldaña, Ma Consolación
المصدر: Villa-Jaimes , G S , Moshage , H , Avelar-González , F J , González-Ponce , H A , Buist-Homan , M , Guevara-Lara , F , Sánchez-Alemán , E , Martínez-Hernández , S L , Ventura-Juárez , J , Muñoz-Ortega , M H & Martínez-Saldaña , M C 2023 , ' Molecular and Antioxidant Characterization of Opuntia robusta Fruit Extract and Its Protective Effect against Diclofenac-Induced Acute Liver Injury in an In Vivo Rat Model ' , Antioxidants , vol. 12 , no. 1 , 113 . https://doi.org/10.3390/antiox12010113
مصطلحات موضوعية: antioxidant response, bioactive compounds, diclofenac, dietary antioxidants, liver failure, oxidative stress biomarkers
وصف الملف: application/pdf
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14Academic Journal
المصدر: Arroyave-Ospina , J C , Buist-Homan , M , Schmidt , M & Moshage , H 2023 , ' Protective effects of caffeine against palmitate-induced lipid toxicity in primary rat hepatocytes is associated with modulation of adenosine receptor A1 signaling ' , Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie , vol. 165 , 114884 . https://doi.org/10.1016/j.biopha.2023.114884
مصطلحات موضوعية: Adenosine receptor A1, Adenosine receptors, Caffeine, Lipotoxicity, MAFLD, PKA
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/867da5a1-6a0e-4c1b-a2df-3553b5985416
https://research.rug.nl/en/publications/867da5a1-6a0e-4c1b-a2df-3553b5985416
https://doi.org/10.1016/j.biopha.2023.114884
https://pure.rug.nl/ws/files/729738460/Protective_effects_of_caffeine_against_palmitate-induced_lipid_toxicity_in_primary_rat_hepatocytes_is_associated_with_modulation_of_adenosine_receptor_A1_signaling.pdf -
15Academic Journal
المؤلفون: Trillos-Almanza, Maria Camila, Wessel, Hanna, Martínez-Aguilar, Magnolia, van den Berg, Eline H., Douwes, Rianne M., Moshage, Han, Connelly, Margery A., Bakker, Stephan J.L., de Meijer, Vincent E., Dullaart, Robin P.F., Blokzijl, Hans
المصدر: Trillos-Almanza , M C , Wessel , H , Martínez-Aguilar , M , van den Berg , E H , Douwes , R M , Moshage , H , Connelly , M A , Bakker , S J L , de Meijer , V E , Dullaart , R P F & Blokzijl , H 2023 , ' Branched Chain Amino Acids Are Associated with Physical Performance in Patients with End-Stage Liver Disease ' , Biomolecules , vol. 13 , no. 5 , 824 . https://doi.org/10.3390/biom13050824
مصطلحات موضوعية: chronic liver disease, essential amino acids, frailty, functional performance, hepatic cirrhosis, hepatic encephalopathy, liver transplantation, magnetic resonance spectroscopy, muscle development, sarcopenia
وصف الملف: application/pdf
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16Academic Journal
المؤلفون: Zhang, Mengfan, Wu, Zongmei, Salas, Sandra Serna, Aguilar, Magnolia Martinez, Trillos-Almanza, Maria C., Buist-Homan, Manon, Moshage, Han
المصدر: Zhang , M , Wu , Z , Salas , S S , Aguilar , M M , Trillos-Almanza , M C , Buist-Homan , M & Moshage , H 2023 , ' Arginase 1 expression is increased during hepatic stellate cell activation and facilitates collagen synthesis ' , Journal of Cellular Biochemistry , vol. 124 , no. 6 , pp. 808-817 . https://doi.org/10.1002/jcb.30403
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/08b2dd9d-f651-4b9a-831f-54750d6a0eae
https://research.rug.nl/en/publications/08b2dd9d-f651-4b9a-831f-54750d6a0eae
https://doi.org/10.1002/jcb.30403
https://pure.rug.nl/ws/files/701985295/Arginase_1_expression_is_increased_during_hepatic_stellate_cell_activation_and_facilitates_collagen_synthesis.pdf -
17Academic Journal
المؤلفون: Haijer, Floris, Koets-Shajari, Shiva, Heegsma, Janette, Serna-Salas, Sandra, Blokzijl, Tjasso, Buist-Homan, Manon, Moshage, Han, Faber, Klaas Nico
المصدر: Haijer , F , Koets-Shajari , S , Heegsma , J , Serna-Salas , S , Blokzijl , T , Buist-Homan , M , Moshage , H & Faber , K N 2023 , ' Hydroxyurea attenuates hepatic stellate cell proliferation in vitro and liver fibrogenesis in vivo ' , The FASEB Journal , vol. 37 , no. 9 , e23124 . https://doi.org/10.1096/fj.202300920R
مصطلحات موضوعية: Mice, Rats, Animals, Hydroxyurea/adverse effects, Hepatic Stellate Cells/metabolism, Inbred C57BL, Liver/metabolism, Liver Cirrhosis/chemically induced, Necrosis/pathology, Collagen/metabolism, Cell Proliferation, RNA, Messenger/genetics, Carbon Tetrachloride/toxicity
وصف الملف: application/pdf
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18Academic Journal
المؤلفون: Stephan Drexler, Cai, Chen, Hartmann, Anna-Lena, Moch, Denise, Gaitantzi, Haristi, Ney, Theresa, Kraemer, Malin, Chu, Yuan, Zheng, Yuwei, Rahbari, Mohammad, Treffs, Annalena, Reiser, Alena, Lenoir, Bénédicte, Valous, Nektarios A., Jäger, Dirk, Birgin, Emrullah, Sawant, Tejas A., Li, Qi, Xu, Keshu, Dong, Lingyue, Otto, Mirko, Itzel, Timo, Teufel, Andreas, Gretz, Norbert, Hawinkels, Lukas J.A.C., Sánchez Muñoz, Aranzazu, Herrera González, Blanca María, Schubert, Rudolf, Moshage, Han, Reissfelder, Christoph, Ebert, Matthias P.A., Rahbari, Nuh N., Breitkopf-Heinlein, Katja
مصطلحات موضوعية: 577.1, 577.2, Diabetes, BMP-9, GDF2, Obesity, Liver steatosis, Biología molecular (Farmacia), Bioquímica (Farmacia), 24 Ciencias de la Vida
وصف الملف: application/pdf
Relation: 394046768-SFB1366; Drexler, Stephan, et al. «Intestinal BMP-9 Locally Upregulates FGF19 and Is down-Regulated in Obese Patients with Diabetes». Molecular and Cellular Endocrinology, vol. 570, junio de 2023, p. 111934. DOI.org (Crossref), https://doi.org/10.1016/j.mce.2023.111934.; https://hdl.handle.net/20.500.14352/107179
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19Academic Journal
المؤلفون: Li, Youhai, Faiz, Alen, Moshage, Han, Schilling, Lothar, Kamps, Jan A.A.M.
المصدر: Li , Y , Faiz , A , Moshage , H , Schilling , L & Kamps , J A A M 2023 , ' Responses of retinal and brain microvasculature to streptozotocin induced diabetes revealed by global expression profiling ' , Diabetes and Vascular Disease Research , vol. 20 , no. 1 , pp. 1-10 . https://doi.org/10.1177/14791641221147533
مصطلحات موضوعية: brain, diabetes, gene expression profiling, microvasculature, Retina
وصف الملف: application/pdf
الاتاحة: https://hdl.handle.net/11370/e2a49248-8b1c-4ae6-a440-2706bd438b2e
https://research.rug.nl/en/publications/e2a49248-8b1c-4ae6-a440-2706bd438b2e
https://doi.org/10.1177/14791641221147533
https://pure.rug.nl/ws/files/750626640/li-et-al-2023-responses-of-retinal-and-brain-microvasculature-to-streptozotocin-induced-diabetes-revealed-by-global.pdf -
20Academic Journal
المؤلفون: Zhang, Mengfan, Damba, Turtushikh, Wu, Zongmei, Serna-Salas, Sandra, Buist-Homan, Manon, Faber, Klaas Nico, Moshage, Han
المصدر: Zhang , M , Damba , T , Wu , Z , Serna-Salas , S , Buist-Homan , M , Faber , K N & Moshage , H 2022 , ' Bioactive coumarin-derivative esculetin decreases hepatic stellate cell activation via induction of cellular senescence via the PI3K-Akt-GSK3β pathway ' , Food Bioscience , vol. 50 , 102164 . https://doi.org/10.1016/j.fbio.2022.102164
مصطلحات موضوعية: Akt, Esculetin, Fibrosis, Hepatic stellate cell, P21, Senescence
وصف الملف: application/pdf