يعرض 1 - 20 نتائج من 52 نتيجة بحث عن '"Morohashi, Akio"', وقت الاستعلام: 0.54s تنقيح النتائج
  1. 1
    Academic Journal
    Pre‐clinical Characterization of Absorption, Distribution, Metabolism and Excretion Properties of TAK‐063

    المؤلفون: Tohyama, Kimio, Sudo, Miyako, Morohashi, Akio, Kato, Suguru, Takahashi, Junzo, Tagawa, Yoshihiko

    المساهمون: Takeda Pharmaceutical Company

    المصدر: Basic & Clinical Pharmacology & Toxicology ; volume 122, issue 6, page 577-587 ; ISSN 1742-7835 1742-7843

    الاتاحة: http://dx.doi.org/10.1111/bcpt.12964
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fbcpt.12964
    https://onlinelibrary.wiley.com/doi/pdf/10.1111/bcpt.12964

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  2. 2
    Academic Journal
    Investigation of disposition for TAK-448, a synthetic peptide of kisspeptin analog, in rats and dogs using the radiolabeled TAK-448 suitable for pharmacokinetic study

    المؤلفون: Moriya, Yuu, Kogame, Akifumi, Tagawa, Yoshihiko, Morohashi, Akio, Kondo, Takahiro, Asahi, Satoru

    المصدر: Xenobiotica ; volume 49, issue 7, page 833-839 ; ISSN 0049-8254 1366-5928

    الاتاحة: https://doi.org/10.1080/00498254.2018.1499152
    https://www.tandfonline.com/doi/pdf/10.1080/00498254.2018.1499152

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  3. 3
    Academic Journal
    Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs

    المؤلفون: Kogame, Akifumi, Takeuchi, Toshiyuki, Nonaka, Masami, Yamasaki, Hitomi, Kawaguchi, Naohiro, Bernards, Ai, Tagawa, Yoshihiko, Morohashi, Akio, Kondo, Takahiro, Moriwaki, Toshiya, Asahi, Satoru

    المصدر: Xenobiotica ; volume 47, issue 3, page 255-266 ; ISSN 0049-8254 1366-5928

    الاتاحة: https://doi.org/10.1080/00498254.2016.1182667
    https://www.tandfonline.com/doi/pdf/10.1080/00498254.2016.1182667

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  4. 4
    Academic Journal
    In vitro metabolism of TAK-438, vonoprazan fumarate, a novel potassium-competitive acid blocker

    المؤلفون: Yamasaki, Hitomi, Kawaguchi, Naohiro, Nonaka, Masami, Takahashi, Junzo, Morohashi, Akio, Hirabayashi, Hideki, Moriwaki, Toshiya, Asahi, Satoru

    المصدر: Xenobiotica ; volume 47, issue 12, page 1027-1034 ; ISSN 0049-8254 1366-5928

    الاتاحة: https://doi.org/10.1080/00498254.2016.1203505
    https://www.tandfonline.com/doi/pdf/10.1080/00498254.2016.1203505

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  5. 5
    Academic Journal
    Absorption of TAK-491, a new angiotensin II receptor antagonist, in animals

    المؤلفون: Kawaguchi, Naohiro, Ebihara, Takuya, Takeuchi, Toshiyuki, Morohashi, Akio, Yamasaki, Hitomi, Tagawa, Yoshihiko, Takahashi, Junzo, Kondo, Takahiro, Asahi, Satoru

    المصدر: Xenobiotica ; volume 43, issue 2, page 182-192 ; ISSN 0049-8254 1366-5928

    الاتاحة: http://dx.doi.org/10.3109/00498254.2012.708797
    http://www.tandfonline.com/doi/pdf/10.3109/00498254.2012.708797

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  6. 6
    Academic Journal
    Investigation of disposition for TAK-448, a synthetic peptide of kisspeptin analog, in rats and dogs using the radiolabeled TAK-448 suitable for pharmacokinetic study.

    المؤلفون: Moriya, Yuu, Kogame, Akifumi, Tagawa, Yoshihiko, Morohashi, Akio, Kondo, Takahiro, Asahi, Satoru

    المصدر: Xenobiotica; Jul2019, Vol. 49 Issue 7, p833-839, 7p

    مصطلحات موضوعية: PEPTIDES, KISSPEPTIN neurons, RADIOLABELING, BLADDER, RADIOACTIVITY


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  7. 7
    Academic Journal
    Application of high‐resolution ESI and MALDI mass spectrometry to metabolite profiling of small interfering RNA duplex

    المؤلفون: Shimizu, Hisao, Jinno, Fumihiro, Morohashi, Akio, Yamazaki, Yuzo, Yamada, Masaki, Kondo, Takahiro, Asahi, Satoru

    المصدر: Journal of Mass Spectrometry ; volume 47, issue 8, page 1015-1022 ; ISSN 1076-5174 1096-9888

    الاتاحة: http://dx.doi.org/10.1002/jms.3054
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fjms.3054
    http://onlinelibrary.wiley.com/wol1/doi/10.1002/jms.3054/fullpdf

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  8. 8
    Academic Journal
    Optimization of (2,3-Dihydro-1-benzofuran-3-yl)acetic Acids: Discovery of a Non-Free Fatty Acid-Like, Highly Bioavailable G Protein-Coupled Receptor 40/Free Fatty Acid Receptor 1 Agonist as a Glucose-Dependent Insulinotropic Agent

    المؤلفون: Negoro, Nobuyuki, Sasaki, Shinobu, Mikami, Satoshi, Ito, Masahiro, Tsujihata, Yoshiyuki, Ito, Ryo, Suzuki, Masami, Takeuchi, Koji, Suzuki, Nobuhiro, Miyazaki, Junichi, Santou, Takashi, Odani, Tomoyuki, Kanzaki, Naoyuki, Funami, Miyuki, Morohashi, Akio, Nonaka, Masami, Matsunaga, Shinichiro, Yasuma, Tsuneo, Momose, Yu

    المصدر: Journal of Medicinal Chemistry ; volume 55, issue 8, page 3960-3974 ; ISSN 0022-2623 1520-4804

    الاتاحة: http://dx.doi.org/10.1021/jm300170m
    https://pubs.acs.org/doi/pdf/10.1021/jm300170m

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  9. 9
    Periodical
    The Enhancement of Subcutaneous First-Pass Metabolism Causes Nonlinear Pharmacokinetics of TAK-448 after a Single Subcutaneous Administration to Rats▪

    المؤلفون: Moriya, Yuu, Kogame, Akifumi, Tagawa, Yoshihiko, Morohashi, Akio, Kondo, Takahiro, Asahi, Satoru, Benet, Leslie Z.

    المصدر: Drug Metabolism and Disposition; September 2019, Vol. 47 Issue: 9 p1004-1012, 9p

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  10. 10
    Periodical
    Characterization of Fasiglifam-Related Liver Toxicity in Dogs▪

    المؤلفون: Kogame, Akifumi, Moriya, Yuu, Mori, Ikuo, Pan, Liping, Morohashi, Akio, Ebihara, Takuya, Fukui, Hideo, Tagawa, Yoshihiko, Benet, Leslie Z.

    المصدر: Drug Metabolism and Disposition; May 2019, Vol. 47 Issue: 5 p525-534, 10p

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  11. 11
    Academic Journal
    Chemical reactivity of ethyl (6R)-6-[N-(2-chloro-4-fluorophenyl)sulfamoyl]cyclohex-1-ene-1-carboxylate (TAK-242) in vitro ; CHEMICAL REACTIVITY OF TAK-242 IN VITRO

    المؤلفون: Jinno, Fumihiro, Yoneyama, Tomoki, Morohashi, Akio, Kondo, Takahiro, Asahi, Satoru

    المصدر: Biopharmaceutics & Drug Disposition ; volume 32, issue 7, page 408-425 ; ISSN 0142-2782

    الاتاحة: http://dx.doi.org/10.1002/bdd.769
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbdd.769
    https://onlinelibrary.wiley.com/doi/full/10.1002/bdd.769

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  12. 12
    Academic Journal
    In vitro metabolism of TAK-438, vonoprazan fumarate, a novel potassium-competitive acid blocker.

    المؤلفون: Yamasaki, Hitomi, Kawaguchi, Naohiro, Nonaka, Masami, Takahashi, Junzo, Morohashi, Akio, Hirabayashi, Hideki, Moriwaki, Toshiya, Asahi, Satoru

    المصدر: Xenobiotica; Dec2017, Vol. 47 Issue 12, p1027-1034, 8p

    مصطلحات موضوعية: METABOLISM, GASTRIC acid, POTASSIUM, BISOPROLOL, LIVER cells, PHARMACOKINETICS


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  13. 13
    Academic Journal
    Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs.

    المؤلفون: Kogame, Akifumi, Takeuchi, Toshiyuki, Nonaka, Masami, Yamasaki, Hitomi, Kawaguchi, Naohiro, Bernards, Ai, Tagawa, Yoshihiko, Morohashi, Akio, Kondo, Takahiro, Moriwaki, Toshiya, Asahi, Satoru

    المصدر: Xenobiotica; Mar2017, Vol. 47 Issue 3, p255-266, 12p

    مصطلحات موضوعية: METABOLITES, PHARMACOKINETICS, CYTOCHROME P-450, PROTON pump inhibitors, INTESTINAL diseases


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  14. 14
    Academic Journal
    Solution structure of the DNA-binding domain of MafG

    المؤلفون: Kusunoki, Hideki, Motohashi, Hozumi, Katsuoka, Fumiki, Morohashi, Akio, Yamamoto, Masayuki, Tanaka, Toshiyuki

    المصدر: Nature Structural Biology ; volume 9, issue 4, page 252-256 ; ISSN 1072-8368

    الاتاحة: http://dx.doi.org/10.1038/nsb771

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  15. 15
    Academic Journal
    Absolute configuration at C14 and C85 in prymnesin‐2, a potent hemolytic and ichthyotoxic glycoside isolated from the red tide alga Prymnesium parvum

    المؤلفون: Morohashi, Akio, Satake, Masayuki, Oshima, Yasukatsu, Igarashi, Tomoji, Yasumoto, Takeshi

    المصدر: Chirality ; volume 13, issue 9, page 601-605 ; ISSN 0899-0042 1520-636X

    الاتاحة: http://dx.doi.org/10.1002/chir.1184
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchir.1184
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chir.1184

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  16. 16
    Academic Journal
    ChemInform Abstract: The Absolute Configuration of Gambieric Acids A—D, Potent Antifungal Polyethers, Isolated from the Marine Dinoflagellate Gambierdiscus toxicus.

    المؤلفون: Morohashi, Akio, Satake, Masayuki, Nagai, Hiroshi, Oshima, Yasukatsu, Yasumoto, Takeshi

    المصدر: ChemInform ; volume 32, issue 5 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.200105243
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.200105243
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.200105243

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  17. 17
    Academic Journal
    Absolute Configuration at C45 in 45-Hydroxyyessotoxin, a Marine Polyether Toxin Isolated from Shellfish

    المؤلفون: MOROHASHI, Akio, SATAKE, Masayuki, OSHIMA, Yasukatsu, YASUMOTO, Takeshi

    المصدر: Bioscience, Biotechnology, and Biochemistry ; volume 64, issue 8, page 1761-1763 ; ISSN 0916-8451 1347-6947

    مصطلحات موضوعية: Organic Chemistry, Molecular Biology, Applied Microbiology and Biotechnology, General Medicine, Biochemistry, Analytical Chemistry, Biotechnology

    الاتاحة: http://dx.doi.org/10.1271/bbb.64.1761
    http://www.tandfonline.com/doi/pdf/10.1271/bbb.64.1761

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  18. 18
    Academic Journal
    The Absolute Configuration of Gambieric Acids A–D, Potent Antifungal Polyethers, Isolated from the Marine Dinoflagellate Gambierdiscus toxicus

    المؤلفون: Morohashi, Akio, Satake, Masayuki, Nagai, Hiroshi, Oshima, Yasukatsu, Yasumoto, Takeshi

    المساهمون: Core Research for Evolutional Science and Technology, Ministry of Education, Culture, Sports, Science and Technology

    المصدر: Tetrahedron ; volume 56, issue 46, page 8995-9001 ; ISSN 0040-4020

    الاتاحة: http://dx.doi.org/10.1016/s0040-4020(00)00753-5
    https://api.elsevier.com/content/article/PII:S0040402000007535?httpAccept=text/xml
    https://api.elsevier.com/content/article/PII:S0040402000007535?httpAccept=text/plain

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  19. 19
    Academic Journal
    Brevetoxin B4 isolated from greenshell musselsPerna canaliculus, the major toxin involved in neurotoxic shellfish poisoning in New Zealand

    المؤلفون: Morohashi, Akio, Satake, Masayuki, Naoki, Hideo, Kaspar, Heinrich F., Oshima, Yasukatsu, Yasumoto, Takeshi

    المصدر: Natural Toxins ; volume 7, issue 2, page 45-48 ; ISSN 1056-9014 1522-7189

    الاتاحة: http://dx.doi.org/10.1002/(sici)1522-7189(199903/04)7:2%3C45::aid-nt34%3E3.0.co%3B2-h
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2F(SICI)1522-7189(199903%2F04)7:2%3C45::AID-NT34%3E3.0.CO%3B2-H
    https://onlinelibrary.wiley.com/doi/full/10.1002/(SICI)1522-7189(199903/04)7:2%3C45::AID-NT34%3E3.0.CO%3B2-H

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  20. 20
    Academic Journal
    ChemInform Abstract: The Absolute Configuration of Gambierol, a Toxic Marine Polyether from the Dinoflagellate, Gambierdiscus toxicus.

    المؤلفون: Morohashi, Akio, Satake, Masayuki, Yasumoto, Takeshi

    المصدر: ChemInform ; volume 30, issue 14 ; ISSN 0931-7597 1522-2667

    الاتاحة: http://dx.doi.org/10.1002/chin.199914274
    https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fchin.199914274
    https://onlinelibrary.wiley.com/doi/pdf/10.1002/chin.199914274

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