المؤلفون: Agata Braniewska, Marcin Skorzynski, Zuzanna Sas, Magdalena Dlugolecka, Ilona Marszalek, Daria Kurpiel, Marcel Bühler, Damian Strzemecki, Aneta Magiera, Maciej Bialasek, Jaroslaw Walczak, Lukasz Cheda, Michal Komorowski, Tobias Weiss, Małgorzata Czystowska-Kuzmicz, Karina Kwapiszewska, Alberto Boffi, Magdalena Krol, Tomasz P. Rygiel

المصدر: Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-21 (2024)

مصطلحات موضوعية: Hemoglobin, Macrophages, CD163, Extracellular vesicles, Monomethyl auristatin E, Medicine, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1478-811X

URL الوصول: https://doaj.org/article/9dd74c0442634d2aa5b9dc140bdf191e

المؤلفون: Xiaojie Chu, Seungmin Shin, Du-San Baek, Liyong Zhang, Alex Conard, Megan Shi, Ye-Jin Kim, Cynthia Adams, Maggie Hines, Xianglei Liu, Chuan Chen, Zehua Sun, Dontcho V. Jelev, John W. Mellors, Dimiter S. Dimitrov, Wei Li

المصدر: mAbs, Vol 16, Iss 1 (2024)

مصطلحات موضوعية: Antibody drug conjugate, fully human antibody, monomethyl auristatin E, prostate cancer, PSCA, tumor xenograft mouse model, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

URL الوصول: https://doaj.org/article/1f085d6811ce4dcda8bde14f50a5302f

المؤلفون: Siming Li, Yanxia Shi, Haiying Dong, Hongqian Guo, Yu Xie, Zhongquan Sun, Xiaoping Zhang, Eric Kim, Jun Zhang, Yue Li, Chenming Xu, Haishan Kadeerbai, Sue Lee, Seema Gorla, Jun Guo, Xinan Sheng

المصدر: Cancer Medicine, Vol 13, Iss 21, Pp n/a-n/a (2024)

مصطلحات موضوعية: antibody–drug conjugates, efficacy, monomethyl auristatin E, safety, urothelial carcinoma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-7634

URL الوصول: https://doaj.org/article/1a50bf8eb8e543569cb07e1e31c9b6f3

المؤلفون: Jingyue Kang, Zongliang Zhang, Ruyuan Zhang, Meijun Zheng, Caiying Jiang, Hui Yang, Aiping Tong, Yan Zhang

المصدر: MedComm – Oncology, Vol 3, Iss 2, Pp n/a-n/a (2024)

مصطلحات موضوعية: antibody‐drug conjugate, malignant pleural mesothelioma, monoclonal antibody, monomethyl auristatin E, V‐domain immunoglobulin suppressor of T cell activation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2769-6448

URL الوصول: https://doaj.org/article/2da3a3df5a434fec95a29dc61720a1b3

المؤلفون: Shun Uchida, Satoshi Serada, Yuji Suzuki, Eiji Funajima, Kei Kitakami, Kazumasa Dobashi, Satomi Tamatani, Yuichi Sato, Takaaki Beppu, Kuniaki Ogasawara, Testuji Naka

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 50, Iss , Pp 100982- (2024)

مصطلحات موضوعية: Antibody–drug conjugate, Glypican-1, Monomethyl auristatin E, Glioblastoma, Blood–brain barrier, Evans blue, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558624000198; https://doaj.org/toc/1476-5586

URL الوصول: https://doaj.org/article/937a68df2d134b64927973de614e8c9c

المؤلفون: Changqiang Xie, Yan Wang, Zhenzhen Cai, Jianghai Du, Zhengyu Chen, Junjie Wang, Xingzhou Peng

المصدر: Journal of Innovative Optical Health Sciences, Vol 17, Iss 02 (2024)

مصطلحات موضوعية: Monomethyl auristatin E, poly (lactic-co-glycolic acid) nanoparticles, sustained release, chemotherapy, immunogenic cell death, Technology, Optics. Light, QC350-467

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1793-5458; https://doaj.org/toc/1793-7205

URL الوصول: https://doaj.org/article/e11796a6ac30407488bf9a2a949eedef

المؤلفون: Barbara Bernardim, João Conde, Tuuli Hakala, Julie B. Becher, Mary Canzano, Aldrin V. Vasco, Tuomas P. J. Knowles, Jason Cameron, Gonçalo J. L. Bernardes

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Computational Biology, Space Science, Chemical Sciences not elsewhere classified, valine – citrulline, selective antitumor activity, question whether protease, pronounced antitumor activity, preferable tumor biodistribution, potent antitumor activity, monomethyl auristatin e, effective pharmaceutical treatments, linker – payload, >)]- containing linker, plasma stable conjugates, human serum albumin, >)] linker , synthesized  one, protease cleavable linkers, cathepsin b processing, retained fcrn binding, >)] linker, cathepsin b

Relation: https://figshare.com/articles/journal_contribution/Cathepsin_B_Processing_Is_Required_for_the_i_In_Vivo_i_Efficacy_of_Albumin_Drug_Conjugates/25205942

الاتاحة: https://doi.org/10.1021/acs.bioconjchem.3c00478.s001
https://figshare.com/articles/journal_contribution/Cathepsin_B_Processing_Is_Required_for_the_i_In_Vivo_i_Efficacy_of_Albumin_Drug_Conjugates/25205942

المؤلفون: Harel, Efrat T, Drake, Penelope M, Barfield, Robyn M, Lui, Irene, Farr-Jones, Shauna, Van't Veer, Laura, Gartner, Zev J, Green, Evan M, Lourenço, André Luiz, Cheng, Yifan, Hann, Byron C, Rabuka, David, Craik, Charles S

المصدر: Antibodies (Basel, Switzerland). 8(4)

مصطلحات موضوعية: antibody-drug conjugate, cleavable linker, maytansinoid, monomethyl auristatin E, non-cleavable linker, site-specific conjugations, targeted therapy, triple-negative breast cancer, urokinase receptor

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/61k4b4nr

المؤلفون: Marco Zambra, Ivan Ranđelović, Francesco Talarico, Adina Borbély, Laura Svajda, József Tóvári, Gábor Mező, Lizeth Bodero, Sveva Colombo, Federico Arrigoni, Elettra Fasola, Silvia Gazzola, Umberto Piarulli

المصدر: Frontiers in Pharmacology, Vol 14 (2023)

مصطلحات موضوعية: drug release, tumor targeting, small molecule-drug conjugate, monomethyl auristatin E, cleavable linker, drug delivery, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1215694/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/8398d4cb126548328281d797762b4133

المؤلفون: Ayana Uchimura, Hajime Yasuda, Jun Ando, Yasunori Ota, Makoto Sasaki, Tomoiku Takaku, Yutaka Tsukune, Miyuki Tsutsui, Yoko Edahiro, Naoki Watanabe, Tomonori Ochiai, Norio Komatsu, Miki Ando

المصدر: Case Reports in Oncology, Vol 15, Iss 1, Pp 263-266 (2022)

مصطلحات موضوعية: castleman disease, doxorubicin, bleomycin, vinblastine, and dacarbazine, anti-cd30 therapy, monomethyl auristatin e, end-stage renal disease, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.karger.com/Article/FullText/523823; https://doaj.org/toc/1662-6575

URL الوصول: https://doaj.org/article/2360cfab3b874c888bf45da5c3e23ed0

المؤلفون: Zambra, Marco, Randelovic, Ivan, Talarico, Francesco, Borbely, Adina, Svajda, Laura, Tovari, Jozsef, Mezo, Gabor, Bodero, Lizeth, Colombo, Sveva, Arrigoni, Federico, Fasola, Elettra, Gazzola, Silvia, Piarulli, Umberto

مصطلحات موضوعية: drug release, tumor targeting, small molecule-drug conjugate, monomethyl auristatin E, cleavable linker, drug delivery, GPLG-linker, ddc:540

Relation: info:eu-repo/semantics/altIdentifier/issn/1663-9812; info:eu-repo/semantics/altIdentifier/wos/001035253700001; info:eu-repo/semantics/altIdentifier/pmid/37492088; https://nbn-resolving.org/urn:nbn:de:0070-pub-29816246; https://pub.uni-bielefeld.de/record/2981624; https://pub.uni-bielefeld.de/download/2981624/2987038

الاتاحة: https://nbn-resolving.org/urn:nbn:de:0070-pub-29816246
https://pub.uni-bielefeld.de/record/2981624
https://pub.uni-bielefeld.de/download/2981624/2987038

المؤلفون: Nikolai Y. Zyk, Anastasiia S. Garanina, Ekaterina A. Plotnikova, Anton P. Ber, Ekaterina A. Nimenko, Natalia S. Dashkova, Anastasiia A. Uspenskaia, Radik R. Shafikov, Dmitry A. Skvortsov, Stanislav A. Petrov, Andrey A. Pankratov, Nikolai V. Zyk, Alexander G. Majouga, Elena K. Beloglazkina, Aleksei E. Machulkin

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11327

مصطلحات موضوعية: prostate cancer, prostate-specific membrane antigen, targeted drug delivery, bimodal conjugates, monomethyl auristatin E

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Pathology, Diagnostics, and Therapeutics; https://dx.doi.org/10.3390/ijms241411327

الاتاحة: https://doi.org/10.3390/ijms241411327

المؤلفون: Hsuan-Ping Chang, Huyen Khanh Le, Dhaval K. Shah

المصدر: Pharmaceutics, Vol 15, Iss 4, p 1132 (2023)

مصطلحات موضوعية: intratumoral administration, subcutaneous administration, antibody-drug conjugate (ADC), local toxicity, monomethyl auristatin E (MMAE), pharmacokinetics/pharmacodynamics (PK/PD), Pharmacy and materia medica, RS1-441

Relation: https://www.mdpi.com/1999-4923/15/4/1132; https://doaj.org/toc/1999-4923; https://doaj.org/article/69d67a523994457c9d0fe5d412c7292b

الاتاحة: https://doi.org/10.3390/pharmaceutics15041132
https://doaj.org/article/69d67a523994457c9d0fe5d412c7292b

المؤلفون: Man Hagiyama, Takahiro Mimae, Akihiro Wada, Fuka Takeuchi, Azusa Yoneshige, Takao Inoue, Naoyuki Kotoku, Hironobu Hamada, Yoshitaka Sekido, Morihito Okada, Akihiko Ito

المصدر: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

مصطلحات موضوعية: cell adhesion molecule 1 (CADM1), neutralizing antibody, antibody drug complex, monomethyl auristatin E (MMAE), humanized antibody, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.945007/full; https://doaj.org/toc/2296-634X

URL الوصول: https://doaj.org/article/257be0bb6f184393914785936f0d9ed4

المؤلفون: Hanhee Cho, Man Kyu Shim, Yujeong Moon, Sukyung Song, Jinseong Kim, Jiwoong Choi, Jeongrae Kim, Youngjoo Lee, Jung Yeon Park, Yongju Kim, Cheol-Hee Ahn, Mi Ra Kim, Hong Yeol Yoon, Kwangmeyung Kim

المصدر: Pharmaceutics; Volume 14; Issue 10; Pages: 2131

مصطلحات موضوعية: prodrug, monomethyl auristatin E, nanoparticle, targeted therapy, chemotherapy

وصف الملف: application/pdf

Relation: Nanomedicine and Nanotechnology; https://dx.doi.org/10.3390/pharmaceutics14102131

الاتاحة: https://doi.org/10.3390/pharmaceutics14102131

المؤلفون: Hui X, Yuan C, Cao W, Ge W, Zhang D, Dan M, Zhao Q, Liu B, Yao B

المصدر: OncoTargets and Therapy, Vol Volume 15, Pp 331-343 (2022)

مصطلحات موضوعية: antibody-drug conjugates (adcs), site-specific conjugation, engineered microbial transglutaminase, monomethyl auristatin e, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.dovepress.com/an-innovative-site-specific-anti-her2-antibody-drug-conjugate-with-hig-peer-reviewed-fulltext-article-OTT; https://doaj.org/toc/1178-6930; https://doaj.org/article/de109a2d1c564706a5e14afa16ec6448

الاتاحة: https://doaj.org/article/de109a2d1c564706a5e14afa16ec6448

المؤلفون: Zhu, Xiao-Yi, Li, Quan-Xiao, Kong, Yu, Huang, Ke-Ke, Wang, Gang, Wang, Yun-Ji, Lu, Jun, Hua, Guo-Qiang, Wu, Yan-Ling, Ying, Tian-Lei

مصطلحات موضوعية: Cell Line, Tumor, Animals, Humans, Mice, Cell Adhesion Molecules, Carcinoembryonic Antigen, Antineoplastic Agents, Cytotoxins, Immunoconjugates, Xenograft Model Antitumor Assays, GPI-Linked Proteins, Single-Domain Antibodies, CEACAM5, antibody-drug conjugate, monomethyl auristatin E, single-domain antibody, solid tumors, 32 Biomedical and Clinical Sciences, 3211 Oncology and Carcinogenesis, Digestive Diseases, Cancer, Colo-Rectal Cancer, Biotechnology, Rare Diseases, 5 Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, 2 Aetiology, Generic health relevance

جغرافية الموضوع: United States

وصف الملف: Print-Electronic; application/pdf

Relation: Acta pharmacologica Sinica; (2024). Acta Pharmacologica Sinica, 45(3), 609-618.; https://hdl.handle.net/2292/67595; 38030799 (pubmed)

الاتاحة: https://hdl.handle.net/2292/67595
https://doi.org/10.1038/s41401-023-01200-9

المؤلفون: Hui Zhang (7197), Cheng Jin (206733), Lin Zhang (8926), Bo Peng (273834), Yibin Zhang (1426579), Yan Liu (25061), Ling Li (38566), Mao Ye (168067), Wei Xiong (58411), Weihong Tan (9692)

مصطلحات موضوعية: Medicine, Genetics, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, transferrin receptor 1, targeted cancer therapy, promising novel anti, monomethyl auristatin e, despite significant advances, specific aptamer targeting, specific aptamer conjugated, um cell lines, distinguish um cells, specifically targets cd71, mouse xenograft model, explore aptamer, dna aptamer, tumor agent, thus implying, results demonstrated, reliable target, new approaches, general mortality, drug delivery

Relation: https://figshare.com/articles/journal_contribution/CD71-Specific_Aptamer_Conjugated_with_Monomethyl_Auristatin_E_for_the_Treatment_of_Uveal_Melanoma/17296526

الاتاحة: https://doi.org/10.1021/acsami.1c13980.s001

المؤلفون: Sebastian Jäger (1925278), Tim R. Wagner (11048063), Nicolas Rasche (1528096), Harald Kolmar (469939), Stefan Hecht (1352094), Christian Schröter (1648678)

مصطلحات موضوعية: Biochemistry, Medicine, Pharmacology, Biotechnology, Immunology, Cancer, Space Science, Chemical Sciences not elsewhere classified, antigen binding functions, cytotoxic monomethyl auristatin E, conjugation site-dependent serum st., novel antibody format, homodimeric Fc region, HER 2-expressing tumor cells, tissue penetration capabilities, FcRn binding behavior, novel scaffold, Novel Antibody-Based Format, ADC, antigen binding site, Fc Antigen Binding Fragment-Drug Co., conjugate, antigen binding fragments, HER 2-targeting Fcab variants, Targeted Drug Delivery Fragment cry.

Relation: https://figshare.com/articles/journal_contribution/Generation_and_Biological_Evaluation_of_Fc_Antigen_Binding_Fragment-Drug_Conjugates_as_a_Novel_Antibody-Based_Format_for_Targeted_Drug_Delivery/14879630

الاتاحة: https://doi.org/10.1021/acs.bioconjchem.1c00240.s001

المؤلفون: Mareile Boschanski (10904008), Tobias Krüger (10904011), Lennard Karsten (10904014), Georg Falck (10904017), Sarfaraz Alam (462713), Marcus Gerlach (10904020), Benjamin Müller (6336650), Kristian M. Müller (1753624), Norbert Sewald (542162), Thomas Dierks (109391)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Plant Biology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, formylglycine-generating enzymes, monomethyl auristatin E, enzyme activity, MMAE, position-selective generation, reactive sites, formylglycine-generating enzyme, epidermal growth factor receptor, cysteine residues, single-chain antibody, recognition sequences, cell culture, acid sequence motif, CF, ADC, receptor binding

Relation: https://figshare.com/articles/journal_contribution/Site-Specific_Conjugation_Strategy_for_Dual_Antibody_Drug_Conjugates_Using_Aerobic_Formylglycine-Generating_Enzymes/14710099

الاتاحة: https://doi.org/10.1021/acs.bioconjchem.1c00246.s001