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المؤلفون: Edmond Fleischer, Vincent Kam Wai Wong, Thorsten Berg, Sara Abdelfatah, Thomas Efferth, Anette Klinger, Li Jun Yang, Qi Huang, Sami Hamdoun, Henry Johannes Greten, Angela Berg
المصدر: Acta Pharmaceutica Sinica B, Vol 9, Iss 5, Pp 1021-1034 (2019)
Acta Pharmaceutica Sinica. Bمصطلحات موضوعية: PBD, Polo box domain, MTD, maximal tolerance dose, CDC25, cell division cycle 25, HIF-1α, hypoxia-inducible factor 1 α, MST, microscale thermophoresis, IC50, 50% inhibition concentration, MFP, M phase promoting factor, PARP-1, poly(ADP-ribose) polymerase-1, 0302 clinical medicine, FOXO, forkhead box O, Nec-1, necrostatin 1, CDC2, cell division cycle protein 2 homolog, General Pharmacology, Toxicology and Pharmaceutics, Mitotic catastrophe, CDK, cyclin-dependent kinase, 0303 health sciences, Chemistry, Polo-like kinase, Mono-targeted therapy, Cell cycle, BUBR1, budding uninhibited by benzimidazole-related 1, Polo box domain, 030220 oncology & carcinogenesis, PLK1, Polo-like kinase, Necroptosis, Spindle damage, PLK1, IHC, immunohistochemistry, Original article, APC/C, anaphase-promoting complex/cyclosome, PLK3, ABC, avidin-biotin complex, PI, propidium iodide, 03 medical and health sciences, FBS, fetal bovine serum, PDB, Protein Data Bank, Kd, the dissociation constant, Kinase activity, 030304 developmental biology, Akt/PKB signaling pathway, Cell growth, lcsh:RM1-950, LC3, light chain 3, lcsh:Therapeutics. Pharmacology, Cancer research, DAPKs, death-associated protein kinase, 3-MA, 3-methyladenine, DAPI, 4′,6-diamidino-2-phenylindole, SAC, spindle assembly checkpoint