المؤلفون: Mokkawes, Thirakorn, de Visser, Sam P.

المصدر: ChemistryEurope ; volume 3, issue 1 ; ISSN 2751-4765 2751-4765

الاتاحة: https://doi.org/10.1002/ceur.202400067

المؤلفون: Qureshi, Muizz, Mokkawes, Thirakorn, Cao, Yuanxin, De Visser, Samuel

المصدر: Qureshi , M , Mokkawes , T , Cao , Y & De Visser , S 2024 , ' Mechanism of the Oxidative Ring-Closure Reaction During the Gliotoxin Biosynthesis by Cytochrome P450 GliF ' , International Journal of Molecular Sciences , vol. 25 , no. 16 , 8567 . https://doi.org/10.3390/ijms25168567

مصطلحات موضوعية: density functional theory, enzyme catalysis, inorganic reaction mechanisms, cyto- 24 chrome P450 enzymes, mono-oxygenases

Relation: https://research.manchester.ac.uk/en/publications/dfa9ccb2-9b7c-437a-9d94-8bcde0bcd35b

الاتاحة: https://research.manchester.ac.uk/en/publications/dfa9ccb2-9b7c-437a-9d94-8bcde0bcd35b
https://doi.org/10.3390/ijms25168567

المؤلفون: Thomas, Jithin, Mokkawes, Thirakorn, Senft, Laura, Dey, Aniruddha, Gordon, Jesse B., Ivanovic-Burmazovic, Ivana, De Visser, Samuel, Goldberg, David P.

المصدر: Thomas , J , Mokkawes , T , Senft , L , Dey , A , Gordon , J B , Ivanovic-Burmazovic , I , De Visser , S & Goldberg , D P 2024 , ' Axial Ligation Impedes Proton-Coupled Electron-Transfer Reactivity of a Synthetic Compound I Analog ' , Journal of the American Chemical Society|J Am Chem Soc . https://doi.org/10.1021/jacs.3c08950

وصف الملف: application/pdf

Relation: https://research.manchester.ac.uk/en/publications/26f6b0fb-ae59-4502-af2f-e2f81444d028

الاتاحة: https://research.manchester.ac.uk/en/publications/26f6b0fb-ae59-4502-af2f-e2f81444d028
https://doi.org/10.1021/jacs.3c08950
https://pure.manchester.ac.uk/ws/files/298544650/Goldberg_Fe_O_Cz_axial_ligands_ms_4th_revision_Final.pdf

المؤلفون: Sampaio Dias, Artur Hermano, Yadav, Rolly, Mokkawes, Thirakorn, Kumar, Asheesh, Skaf, Munir S., Sastri, Chivukula V., Kumar, Devesh, De Visser, Samuel

المصدر: Sampaio Dias , A H , Yadav , R , Mokkawes , T , Kumar , A , Skaf , M S , Sastri , C V , Kumar , D & De Visser , S 2023 , ' Biotransformation of Bisphenol by Human Cytochrome P450 2C9 Enzymes: a Density Functional Theory Study ' , Inorganic Chemistry , vol. 62 , no. 5 , pp. 2244–2256 . https://doi.org/10.1021/acs.inorgchem.2c03984.s001

مصطلحات موضوعية: Enzyme catalysis, Inorganic Reaction Mechanisms, Heme, Aromatic Hydroxylation, Biodegradation

Relation: https://research.manchester.ac.uk/en/publications/a86ff0f2-277a-4c93-ad3e-a329b26b5c5f

الاتاحة: https://research.manchester.ac.uk/en/publications/a86ff0f2-277a-4c93-ad3e-a329b26b5c5f
https://doi.org/10.1021/acs.inorgchem.2c03984.s001

المؤلفون: Zhang, Yi, Mokkawes, Thirakorn, De visser, Samuel p.

المصدر: Zhang , Y , Mokkawes , T & De visser , S P 2023 , ' Insights into Cytochrome P450 Enzymes Catalyzed Defluorination of Aromatic Fluorides ' , Angewandte Chemie International Edition . https://doi.org/10.1002/anie.202310785

مصطلحات موضوعية: density functional theory, enzyme catalysis, inorganic reaction mechanisms, biocatalysis, hydroxylation

وصف الملف: application/pdf

الاتاحة: https://research.manchester.ac.uk/en/publications/c96846df-f4d2-4f17-b9db-3310d31f2ad6
https://doi.org/10.1002/anie.202310785
https://pure.manchester.ac.uk/ws/files/274730964/Yi_CF_paper_v14.pdf

المؤلفون: Bagha, Umesh Kumar, Yadav, Rolly, Mokkawes, Thirakorn, Satpathy, Jagnyesh Kumar, Kumar, Devesh, Sastri, Chivukula V., De visser, Samuel P.

المصدر: Bagha , U K , Yadav , R , Mokkawes , T , Satpathy , J K , Kumar , D , Sastri , C V & De visser , S P 2023 , ' Defluorination of fluorophenols by a nonheme iron(IV)‐oxo species: observation of a new intermediate along the reaction ' , Chemistry – A European Journal . https://doi.org/10.1002/chem.202300478

مصطلحات موضوعية: inorganic reaction mechanism, biomimetic models, kinetics, defluorination, density functional theory, ResearchInstitutes_Networks_Beacons/manchester_institute_of_biotechnology, Manchester Institute of Biotechnology

وصف الملف: application/pdf

الاتاحة: https://research.manchester.ac.uk/en/publications/d2205404-ec69-46c4-9dc6-a04c8a4d0968
https://doi.org/10.1002/chem.202300478
https://pure.manchester.ac.uk/ws/files/258775897/Fe_N4Py_oxo_v18.pdf

المؤلفون: Mokkawes, Thirakorn, De Visser, Samuel

المصدر: Mokkawes , T & De Visser , S 2023 , ' Caffeine biodegradation by cytochrome P450 1A2. What determines the product distributions? ' , Chemistry: A European Journal . https://doi.org/10.1002/chem.202203875

مصطلحات موضوعية: density functional theory, enzyme catalysis, inorganic reaction mechanisms, heme enzymes, hydroxylation

الاتاحة: https://research.manchester.ac.uk/en/publications/81d7eb36-2a26-490e-9dd4-4739fa702314
https://doi.org/10.1002/chem.202203875

المؤلفون: Gerard, Emilie, Mokkawes, Thirakorn, Johannissen, Linus, Warwicker, James, Spiess, Reynard, Blanford, Christopher F., Hay, Sam, Heyes, Derren, De Visser, Samuel

المصدر: Gerard , E , Mokkawes , T , Johannissen , L , Warwicker , J , Spiess , R , Blanford , C F , Hay , S , Heyes , D & De Visser , S 2023 , ' How is substrate halogenation triggered by the vanadium haloperoxidase from Curvularia inaequalis? ' , ACS Catalysis , vol. 13 , no. 12 . https://doi.org/10.1021/acscatal.3c00761.s001

مصطلحات موضوعية: Halogen transfer, enzyme mechanism, enzyme catalysis, inorganic reaction mechanism, modelling, stopped-flow

Relation: https://research.manchester.ac.uk/en/publications/8d47e2cd-2027-41a4-8e1d-78d27256bd77

الاتاحة: https://research.manchester.ac.uk/en/publications/8d47e2cd-2027-41a4-8e1d-78d27256bd77
https://doi.org/10.1021/acscatal.3c00761.s001

المؤلفون: Hermano Sampaio Dias, Artur, Yadav, Rolly, Mokkawes, Thirakorn, Kumar, Asheesh, Skaf, Munir S., Sastri, Chivukula V., Kumar, Devesh, de Visser, Sam P.

المساهمون: Science and Engineering Research Board, Department of Science and Technology, Ministry of Science and Technology, India, Funda??o de Amparo ? Pesquisa do Estado de S?o Paulo

المصدر: Inorganic Chemistry ; volume 62, issue 5, page 2244-2256 ; ISSN 0020-1669 1520-510X

الاتاحة: http://dx.doi.org/10.1021/acs.inorgchem.2c03984
https://pubs.acs.org/doi/pdf/10.1021/acs.inorgchem.2c03984

المؤلفون: Gérard, Emilie F., Mokkawes, Thirakorn, Johannissen, Linus O., Warwicker, Jim, Spiess, Reynard R., Blanford, Christopher F., Hay, Sam, Heyes, Derren J., de Visser, Sam P.

المساهمون: Biotechnology and Biological Sciences Research Council

المصدر: ACS Catalysis ; volume 13, issue 12, page 8247-8261 ; ISSN 2155-5435 2155-5435

الاتاحة: http://dx.doi.org/10.1021/acscatal.3c00761
https://pubs.acs.org/doi/pdf/10.1021/acscatal.3c00761

المؤلفون: Wong, Henrik, Mokkawes, Thirakorn, De Visser, Sam

المصدر: Wong , H , Mokkawes , T & De Visser , S 2022 , ' Can the isonitrile biosynthesis enzyme ScoE assist with the biosynthesis of isonitrile groups in drug molecules? A computational study ' , Physical Chemistry Chemical Physics . https://doi.org/10.1039/D2CP03409C

الاتاحة: https://research.manchester.ac.uk/en/publications/f5a65707-0344-484c-a145-83f7b46d31ca
https://doi.org/10.1039/D2CP03409C
http://pubs.rsc.org/en/Content/ArticleLanding/2022/CP/D2CP03409C

المؤلفون: Yeh, Chieh-Chih George, Mokkawes, Thirakorn, Bradley, Justin M., Le Brun, Nick E., de Visser, Sam P.

وصف الملف: application/pdf

Relation: https://ueaeprints.uea.ac.uk/id/eprint/85076/1/George_ferritin_paper_v26.pdf; Yeh, Chieh-Chih George, Mokkawes, Thirakorn, Bradley, Justin M., Le Brun, Nick E. and de Visser, Sam P. (2022) Second coordination sphere effects on the mechanistic pathways for dioxygen activation by a ferritin: involvement of a Tyr radical and the identification of a cation binding site. ChemBioChem, 23 (13). ISSN 1439-4227

الاتاحة: https://ueaeprints.uea.ac.uk/id/eprint/85076/
https://ueaeprints.uea.ac.uk/id/eprint/85076/1/George_ferritin_paper_v26.pdf
https://doi.org/10.1002/cbic.202200257

المؤلفون: Yeh, C.-C. George, Ghafoor, Sidra, Satpathy, Jagnyesh Kumar, Mokkawes, Thirakorn, Sastri, Chivukula V., de Visser, Sam P.

المساهمون: Science and Engineering Research Board, UK-India Education and Research Initiative

المصدر: ACS Catalysis ; volume 12, issue 7, page 3923-3937 ; ISSN 2155-5435 2155-5435

الاتاحة: http://dx.doi.org/10.1021/acscatal.1c04029
https://pubs.acs.org/doi/pdf/10.1021/acscatal.1c04029

المؤلفون: Mokkawes, Thirakorn, Lim, Ze Qing, de Visser, Sam P.

المصدر: The Journal of Physical Chemistry B ; volume 126, issue 46, page 9591-9606 ; ISSN 1520-6106 1520-5207

الاتاحة: http://dx.doi.org/10.1021/acs.jpcb.2c07200
https://pubs.acs.org/doi/pdf/10.1021/acs.jpcb.2c07200

المؤلفون: Qureshi, Muizz, Mokkawes, Thirakorn, Cao, Yuanxin, de Visser, Sam P.

المصدر: International Journal of Molecular Sciences; Aug2024, Vol. 25 Issue 16, p8567, 23p

مصطلحات موضوعية: REACTION mechanisms (Chemistry), CYTOCHROME P-450, DENSITY functional theory, BIOCHEMICAL substrates, DRUG synthesis

المؤلفون: Mokkawes, Thirakorn, De Visser, Samuel P.

المصدر: Mokkawes , T & De Visser , S P 2023 , ' Melatonin activation by Cytochrome P450 isozymes. How does CYP1A2 compare to CYP1A1? ' , International Journal of Molecular Sciences .

مصطلحات موضوعية: Enzyme catalysis, Molecular Dynamics, Quantum Mechanics, Inorganic Reaction Mechanisms, Hydroxylation, Regioselectivity

الاتاحة: https://research.manchester.ac.uk/en/publications/ad8a647d-3b33-427a-a034-e2ca862d054f

المؤلفون: Mokkawes, Thirakorn¹ (AUTHOR), De Visser, Tamar¹ (AUTHOR), Cao, Yuanxin¹ (AUTHOR), De Visser, Sam P.¹ (AUTHOR) sam.devisser@manchester.ac.uk

المصدر: Molecules. Oct2023, Vol. 28 Issue 19, p6961. 18p.

مصطلحات موضوعية: *ISOENZYMES, *CYTOCHROME P-450, *ABSTRACTION reactions, *METHOXY group, *ENZYMES

المؤلفون: Yeh, C.-C. George, Mokkawes, Thirakorn, Bradley, Justin M., Le Brun, Nick E., De Visser, Samuel

المصدر: Yeh , C-C G , Mokkawes , T , Bradley , J M , Le Brun , N E & De Visser , S 2022 , ' Second coordination sphere effects on the mechanistic pathways for dioxygen activation by a ferritin: involvement of a Tyr radical and the identification of a cation binding site ' , ChemBioChem: a European journal of chemical biology .

الاتاحة: https://research.manchester.ac.uk/en/publications/fb9d9a51-52f5-46a8-8caf-f79ed04008b3

المؤلفون: Wong, Henrik P. H., Mokkawes, Thirakorn, de Visser, Sam P.

المصدر: Physical Chemistry Chemical Physics (PCCP); 11/28/2022, Vol. 24 Issue 44, p27250-27262, 13p

المؤلفون: Yeh, Chieh‐Chih George, Mokkawes, Thirakorn, Bradley, Justin M., Le Brun, Nick E., de Visser, Sam P.

المصدر: ChemBioChem; 7/5/2022, Vol. 23 Issue 13, p1-9, 9p