المؤلفون: Yuri Takada, Yuki Kitao, Yoshie Fujiwara, Chika Yamamoto, Mitsuhiro Terao, Dan Ohtan Wang, Elghareeb E. Elboray, Yasunobu Yamashita, Yukihiro Itoh, Paolo Mellini, Rohini Roy, Yukari Takahashi, Makoto Oba, Masayuki Kotoku, Takao Yamaguchi, Satoshi Obika, Ritesh Singh, Muthuraj Prakash, Takayoshi Suzuki

المصدر: Journal of medicinal chemistry. 64(21)

مصطلحات موضوعية: Adenosine, endocrine system diseases, Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Down-Regulation, Substrate Specificity, chemistry.chemical_compound, Downregulation and upregulation, Cell Line, Tumor, Drug Discovery, medicine, Humans, Acute monocytic leukemia, Epigenetics, Enzyme Inhibitors, Gene, Messenger RNA, biology, Chemistry, nutritional and metabolic diseases, RNA, pathological conditions, signs and symptoms, medicine.disease, Molecular biology, Up-Regulation, Drug Design, biology.protein, Molecular Medicine, Demethylase, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda13918510b1de8b8f693d2d156f972
https://pubmed.ncbi.nlm.nih.gov/34727689

المؤلفون: Muthuraj Prakash, Yukihiro Itoh, Yoshie Fujiwara, Yukari Takahashi, Yuri Takada, Mellini, Paolo, Elboray, Elghareeb E., Mitsuhiro Terao, Yasunobu Yamashita, Chika Yamamoto, Takao Yamaguchi, Masayuki Kotoku, Yuki Kitao, Singh, Ritesh, Roy, Rohini, Satoshi Obika, Makoto Oba, Dan Ohtan Wang, Takayoshi Suzuki

المصدر: Journal of Medicinal Chemistry; 11/11/2021, Vol. 64 Issue 21, p15810-15824, 15p

المؤلفون: Yasuko Takasu, Tomihiko Aoyama, Mitsuhiro Terao, Yuko Ito, Hiroshi Matsumoto, Hisao Oka, Minae Watanabe, Kentaro Inoue, Tomomi Goto

المصدر: Journal of Liquid Chromatography & Related Technologies. 28:325-334

مصطلحات موضوعية: Reproducibility, food.ingredient, Chromatography, Absorption spectroscopy, Food additive, Clinical Biochemistry, Analytical chemistry, Pharmaceutical Science, Reversed-phase chromatography, Biochemistry, Thin-layer chromatography, Analytical Chemistry, Acetic acid, chemistry.chemical_compound, food, chemistry, Sodium sulfate, Densitometry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::45feecdf649c15ca58c1feffbd91a084
https://doi.org/10.1081/jlc-200041352

المؤلفون: Muthuraj Prakash (1643212), Yukihiro Itoh (433923), Yoshie Fujiwara (27958), Yukari Takahashi (46094), Yuri Takada (11640660), Paolo Mellini (1452205), Elghareeb E. Elboray (5243465), Mitsuhiro Terao (11640663), Yasunobu Yamashita (420508), Chika Yamamoto (11640666), Takao Yamaguchi (2047378), Masayuki Kotoku (1436326), Yuki Kitao (6824891), Ritesh Singh (1307049), Rohini Roy (11640669), Satoshi Obika (738268), Makoto Oba (338218), Dan Ohtan Wang (1634779), Takayoshi Suzuki (172609)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Physiology, Pharmacology, Cancer, Hematology, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, merges key fragments, design novel fto, rna demethylase involved, fat mass obesity, associated protein using, hz (< b, 11b , fto target genes, rna demethylase, associated protein, (< b, various genes, therapeutic target, merging fragments, rara <, n <

Relation: https://figshare.com/articles/journal_contribution/Identification_of_Potent_and_Selective_Inhibitors_of_Fat_Mass_Obesity-Associated_Protein_Using_a_Fragment-Merging_Approach/16922751

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01107.s001