المؤلفون: Shoji Hashimoto, Kazuyuki Yoshizaki, Kazuko Uno, Heita Kitajima, Tsuyoshi Arai, Yoshitaka Tamura, Hiroshi Morishita, Hiroto Matsuoka, Yuki Han, Seijiro Minamoto, Tomonori Hirashima, Tomoki Yamada, Yozo Kashiwa, Makoto Kameda, Seiji Yamaguchi, Yasunari Tsuchihashi, Mitsuhiro Iwahashi, Emi Nakayama, Tatsuo Shioda, Takayuki Nagai, Toshio Tanaka

المصدر: Frontiers in Medicine, Vol 8 (2021)

مصطلحات موضوعية: COVID-19, cytokine storm, IL-6, tocilizumab, dexamethasone, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2021.734838/full; https://doaj.org/toc/2296-858X

URL الوصول: https://doaj.org/article/59df56ed85ed4c4b8f36715d9ba6fd85

المؤلفون: Kazuko Uno, Kazuyuki Yoshizaki, Mitsuhiro Iwahashi, Jiro Yamana, Seizo Yamana, Miki Tanigawa, Katsumi Yagi

المصدر: PLoS ONE, Vol 10, Iss 7, p e0132055 (2015)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4503565?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/a1041431e7ec4eceb79bdac8c7372939

المؤلفون: Jiro Yamana, Mitsuhiro Iwahashi, Motoaki Kin, Rie Sasaki, Seizo Yamana, 佐々木 理恵, 山名 二郎, 山名 征三, 岩橋 充啓, 金 基哲

المصدر: Nihon Rinsho Men'eki Gakkai Sokai Shorokushu. 2007, :73

المؤلفون: Jiro Yamana, Mitsuhiro Iwahashi, Motoaki Kin, Rie Sasaki, Seizo Yamana, 佐々木 理恵, 山名 二郎, 山名 征三, 岩橋 充啓, 金 基哲

المصدر: Nihon Rinsho Men'eki Gakkai Sokai Shorokushu. 2007, :74

المؤلفون: Fumihiro MITSUNOBU, Hirofumi MAKINO, Hirofumi TSUGENO, Kozo ASIDA, Makoto OKAMOTO, Masahiro YAMAMURA, Masanori KAWASHIMA, Mitsuhiro IWAHASHI, Seishi HARADA, Shingo TAKATA, Takashi MIFUNE, Yasuhiro HOSAKI, Yoshiro TANIZAKI

المصدر: Internal Medicine. 2001, 40(2):140

المؤلفون: Takeshi Takasago, Ryohei Hayashi, Yoshitaka Ueno, Ken Yamashita, Shiro Oka, Rie Sasaki, Mika Norii, Mitsuhiro Iwahashi, Fumio Shimamoto, Shinji Tanaka

المصدر: Clinical Journal of Gastroenterology. 15:924-928

مصطلحات موضوعية: Diarrhea, Male, Recombinant Fusion Proteins, Gastroenterology, General Medicine, Middle Aged, Abatacept, Arthritis, Rheumatoid, CD28 Antigens, Antirheumatic Agents, Immunoglobulin G, Humans, CTLA-4 Antigen, Colitis, Ulcerative, Gastrointestinal Hemorrhage, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2932949c86b70e1afd822db5abd38bd
https://doi.org/10.1007/s12328-022-01653-1

المؤلفون: Yasutsugu Nagamoto, Mitsuhiro Iwahashi, Hirofumi Watanabe, Rie Sasaki, Masamoto Funaki, Kazutoshi Yukawa, Jiro Yamana, Seizo Yamana

المصدر: JCR: Journal of Clinical Rheumatology. 24:355-360

مصطلحات موضوعية: Male, medicine.medical_specialty, Arthritis, Pneumocystis carinii, urologic and male genital diseases, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, Rheumatology, Risk Factors, Internal medicine, Trimethoprim, Sulfamethoxazole Drug Combination, medicine, Humans, 030212 general & internal medicine, Adverse effect, Aged, Retrospective Studies, 030203 arthritis & rheumatology, business.industry, Pneumonia, Pneumocystis, Sulfamethoxazole, Retrospective cohort study, Middle Aged, bacterial infections and mycoses, medicine.disease, Trimethoprim, female genital diseases and pregnancy complications, respiratory tract diseases, Pneumonia, Treatment Outcome, Rheumatoid arthritis, Female, business, Immunosuppressive Agents, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949e31f10a9a37269d16d6281c85bbdd
https://doi.org/10.1097/rhu.0000000000000731

المؤلفون: Shoji Hashimoto (146085), Kazuyuki Yoshizaki (770449), Kazuko Uno (152423), Heita Kitajima (11469901), Tsuyoshi Arai (2150500), Yoshitaka Tamura (10924694), Hiroshi Morishita (11469904), Hiroto Matsuoka (11469907), Yuki Han (11469910), Seijiro Minamoto (11469913), Tomonori Hirashima (493159), Tomoki Yamada (284141), Yozo Kashiwa (11469916), Makoto Kameda (11469919), Seiji Yamaguchi (514015), Yasunari Tsuchihashi (25104), Mitsuhiro Iwahashi (58622), Emi Nakayama (3401096), Tatsuo Shioda (126910), Takayuki Nagai (2180396), Toshio Tanaka (292422)

مصطلحات موضوعية: Dermatology, Emergency Medicine, Gastroenterology and Hepatology, Geriatrics and Gerontology, Intensive Care, Medical Genetics (excl. Cancer Genetics), Nephrology and Urology, Nuclear Medicine, Orthopaedics, Otorhinolaryngology, Pathology (excl. Oral Pathology), Radiology and Organ Imaging, Foetal Development and Medicine, Obstetrics and Gynaecology, Family Care, Primary Health Care, Medical and Health Sciences not elsewhere classified, COVID-19, cytokine storm, IL-6, tocilizumab, dexamethasone

Relation: https://figshare.com/articles/figure/Image_3_Prompt_Reduction_in_CRP_IL-6_IFN-_IP-10_and_MCP-1_and_a_Relatively_Low_Basal_Ratio_of_Ferritin_CRP_Is_Possibly_Associated_With_the_Efficacy_of_Tocilizumab_Monotherapy_in_Severely_to_Critically_Ill_Patients_With_COVID-19_jpg/16664797

الاتاحة: https://doi.org/10.3389/fmed.2021.734838.s004

المؤلفون: Shoji Hashimoto (146085), Kazuyuki Yoshizaki (770449), Kazuko Uno (152423), Heita Kitajima (11469901), Tsuyoshi Arai (2150500), Yoshitaka Tamura (10924694), Hiroshi Morishita (11469904), Hiroto Matsuoka (11469907), Yuki Han (11469910), Seijiro Minamoto (11469913), Tomonori Hirashima (493159), Tomoki Yamada (284141), Yozo Kashiwa (11469916), Makoto Kameda (11469919), Seiji Yamaguchi (514015), Yasunari Tsuchihashi (25104), Mitsuhiro Iwahashi (58622), Emi Nakayama (3401096), Tatsuo Shioda (126910), Takayuki Nagai (2180396), Toshio Tanaka (292422)

مصطلحات موضوعية: Dermatology, Emergency Medicine, Gastroenterology and Hepatology, Geriatrics and Gerontology, Intensive Care, Medical Genetics (excl. Cancer Genetics), Nephrology and Urology, Nuclear Medicine, Orthopaedics, Otorhinolaryngology, Pathology (excl. Oral Pathology), Radiology and Organ Imaging, Foetal Development and Medicine, Obstetrics and Gynaecology, Family Care, Primary Health Care, Medical and Health Sciences not elsewhere classified, COVID-19, cytokine storm, IL-6, tocilizumab, dexamethasone

Relation: https://figshare.com/articles/dataset/Data_Sheet_1_Prompt_Reduction_in_CRP_IL-6_IFN-_IP-10_and_MCP-1_and_a_Relatively_Low_Basal_Ratio_of_Ferritin_CRP_Is_Possibly_Associated_With_the_Efficacy_of_Tocilizumab_Monotherapy_in_Severely_to_Critically_Ill_Patients_With_COVID-19_docx/16664782

الاتاحة: https://doi.org/10.3389/fmed.2021.734838.s001

المؤلفون: Kazutoshi, Yukawa, Sho, Mokuda, Hiroki, Kohno, Katsuhiro, Oi, Tatsuomi, Kuranobu, Tadahiro, Tokunaga, Yusuke, Yoshida, Jiro, Yamana, Mitsuhiro, Iwahashi, Shintaro, Hirata, Seizo, Yamana, Eiji, Sugiyama

المصدر: Clinical and experimental rheumatology. 38(5)

مصطلحات موضوعية: Abatacept, Arthritis, Rheumatoid, Chemokine CXCL10, Leukocytes, Mononuclear, Humans, Chemokines, Retrospective Studies

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9f727591020f9a8c9f5bb6921415b9db
https://pubmed.ncbi.nlm.nih.gov/31969227

المؤلفون: Mitsuhiro Iwahashi, Kazuko Uno, Kazuyuki Yoshizaki, Keisuke Izumi, Tsutomu Takeuchi, Hitoshi Fujimiya

المصدر: SATURDAY, 15 JUNE 2019.

مصطلحات موضوعية: Infliximab therapy, medicine.medical_specialty, business.industry, Complete remission, Infliximab, Serum cytokine, Serum biomarkers, Internal medicine, medicine, In patient, business, Area under the roc curve, Bristol-Myers, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3742600a43c1a688b0d0c6ba7066e23b
https://doi.org/10.1136/annrheumdis-2019-eular.5358

المؤلفون: Yukihiko Saeki, Kazuhide Tanimura, Masakazu Kondo, Tsukasa Matsubara, Shuji Ohta, Mitsuhiro Iwahashi, Toshio Tanaka, Yukitaka Ueki, Shigeto Tohma, Hiroshi Inoue, Atsushi Ogata, Toyohiko Sugimoto, Yukitomo Urata

المصدر: Arthritis Care & Research

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Injections, Subcutaneous, Arthritis, Rheumatoid Arthritis, Antibodies, Monoclonal, Humanized, law.invention, Arthritis, Rheumatoid, chemistry.chemical_compound, Tocilizumab, Rheumatology, Randomized controlled trial, Double-Blind Method, law, Internal medicine, medicine, Clinical endpoint, Humans, Adverse effect, Infusions, Intravenous, medicine.diagnostic_test, business.industry, Middle Aged, medicine.disease, Surgery, Treatment Outcome, chemistry, Rheumatoid arthritis, Erythrocyte sedimentation rate, Antirheumatic Agents, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae7ac081576269a96b3fb9c6a50966db
http://europepmc.org/articles/PMC4225471

المؤلفون: Toshihide Mimura, Nobuhiro Takagi, Miho Murakami, Takahiko Horiuchi, Masahiro Iwamoto, Yukihiko Saeki, Koichi Amano, Hisaaki Miyahara, Kazuyoshi Saito, Masakazu Kondo, Hitoshi Kohsaka, Tsutomu Takeuchi, Shuji Ohta, Yukitaka Ueki, Jiro Yamana, Kiyoshi Takasugi, Jun Hashimoto, Norihiro Nishimoto, Hajime Sano, Tomonori Ishii, Yasuhiko Hirabayashi, Tomomi Tsuru, Tsukasa Matsubara, Shigeto Tohma, Mitsuhiro Iwahashi, Takaji Matsutani

المصدر: Modern Rheumatology. 24:26-32

مصطلحات موضوعية: Adult, Male, musculoskeletal diseases, Drug, medicine.medical_specialty, media_common.quotation_subject, Antibodies, Monoclonal, Humanized, Severity of Illness Index, Arthritis, Rheumatoid, Disease activity, chemistry.chemical_compound, Tocilizumab, Rheumatology, Recurrence, Internal medicine, Humans, Medicine, In patient, skin and connective tissue diseases, Aged, media_common, business.industry, Antibodies, Monoclonal, Middle Aged, medicine.disease, Infliximab, humanities, Treatment Outcome, chemistry, Antirheumatic Agents, Rheumatoid arthritis, Retreatment, Physical therapy, Drug Therapy, Combination, Female, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f986c1047765280fc7f87509de56c196
https://doi.org/10.3109/14397595.2013.854080

المؤلفون: Kaori Watanabe, Ryoko Sakai, Ryuji Koike, Fumikazu Sakai, Haruhito Sugiyama, Michi Tanaka, Yukiko Komano, Yuji Akiyama, Toshihide Mimura, Motohide Kaneko, Hitoshi Tokuda, Takenobu Iso, Mitsuru Motegi, Kei Ikeda, Hiroshi Nakajima, Hirofumi Taki, Tetsuo Kubota, Hirotaka Kodama, Shoji Sugii, Takashi Kuroiwa, Yasushi Nawata, Kazuko Shiozawa, Atsushi Ogata, Shigemasa Sawada, Yoshihiro Matsukawa, Takahiro Okazaki, Masaya Mukai, Mitsuhiro Iwahashi, Kazuyoshi Saito, Yoshiya Tanaka, Toshihiro Nanki, Nobuyuki Miyasaka, Masayoshi Harigai

المصدر: Modern Rheumatology. 23:1085-1093

مصطلحات موضوعية: Rheumatology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a742e2b279713d8e5782098fff556940
https://doi.org/10.3109/s10165-012-0796-5

المؤلفون: Mika, Norii, Masahiro, Yamamura, Mitsuhiro, Iwahashi, Akiko, Ueno, Jiro, Yamana, Hirofumi, Makino

المصدر: Acta Medica Okayama. 60(3):149-157

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, rheumatoid arthritis, CXCR3, Receptors, CCR4, Receptors, CXCR3, Receptors, CCR5, Synovial Membrane, interleukin-15, CD8-Positive T-Lymphocytes, Middle Aged, Th1 Cells, Flow Cytometry, Ligands, CD4+ T cells, Arthritis, Rheumatoid, Cell Movement, Case-Control Studies, Humans, Female, Receptors, Chemokine, CCR5, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::96a2970aa37b93aeb23ad79b41b1bc20
https://ousar.lib.okayama-u.ac.jp/30745

المؤلفون: Mitsuhiro Iwahashi, Kazuo Akima, Jun Wada, Yasushi Shikata, Shinichi Okada, Hirofumi Makino, Kenichi Shikata, Mitsuhiro Matsuda, Yoshinori Tsuchiyama, Daisuke Ogawa

المصدر: Nephron Experimental Nephrology. 99:e26-e32

مصطلحات موضوعية: Physiology, Polysaccharide, Rats, Inbred WKY, chemistry.chemical_compound, Glomerulonephritis, Sulfation, Adjuvants, Immunologic, stomatognathic system, Hyaluronic acid, Genetics, medicine, Animals, Macrophage, Infusions, Parenteral, Hyaluronic Acid, chemistry.chemical_classification, Nephritis, Chemistry, Crescentic glomerulonephritis, Macrophages, General Medicine, medicine.disease, Immunohistochemistry, Molecular biology, Rats, Disease Models, Animal, Nephrology, Immunology, Disease Progression, Selectins, Female, Selectin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed0d6af6d9d8749150b4cb10529cf5c
https://doi.org/10.1159/000081795

المؤلفون: A. Ueno, Hirofumi Makino, Mitsuhiro Iwahashi, T. Aita, Masahiro Yamamura, Akira Okamoto, Norio Ogawa

المصدر: Rheumatology International. 25:361-367

مصطلحات موضوعية: Male, Chemokine, Receptors, CXCR3, Immunology, Gene Expression, Arthritis, CXCR3, Chemokine CXCL9, Arthritis, Rheumatoid, Interferon-gamma, Chemokine receptor, Rheumatology, immune system diseases, Humans, Immunology and Allergy, Medicine, CXCL10, CXCL11, RNA, Messenger, Cells, Cultured, Aged, Synovitis, biology, Reverse Transcriptase Polymerase Chain Reaction, business.industry, Synovial Membrane, Fibroblasts, Middle Aged, medicine.disease, Chemokine CXCL11, Chemokine CXCL10, Drug Combinations, Cancer research, biology.protein, Intercellular Signaling Peptides and Proteins, CXCL9, Female, Receptors, Chemokine, Tumor necrosis factor alpha, business, Chemokines, CXC

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5599f1efb1d4900d13c52c9c9301ae2
https://doi.org/10.1007/s00296-004-0449-x

المؤلفون: T. Aita, Sachiko Akashi, Akira Okamoto, Hirofumi Makino, Mitsuhiro Iwahashi, Masahiro Yamamura, A. Ueno, Kensuke Miyake, Norio Ogawa, Paul J. Godowski

المصدر: Arthritis & Rheumatism. 50:1457-1467

مصطلحات موضوعية: Adult, Lipopolysaccharides, Male, medicine.medical_treatment, CD14, Immunology, Lipopolysaccharide Receptors, Receptors, Cell Surface, chemical and pharmacologic phenomena, CD16, Ligands, Antibodies, Monocytes, Proinflammatory cytokine, Arthritis, Rheumatoid, Transforming Growth Factor beta1, Rheumatology, Transforming Growth Factor beta, medicine, Humans, Immunology and Allergy, Macrophage, Pharmacology (medical), Cells, Cultured, Membrane Glycoproteins, Tumor Necrosis Factor-alpha, Chemistry, Macrophage Colony-Stimulating Factor, Macrophages, Monocyte, Receptors, IgG, Synovial Membrane, Toll-Like Receptors, NF-kappa B, Chaperonin 60, Middle Aged, Flow Cytometry, Toll-Like Receptor 2, Interleukin-10, Teichoic Acids, Toll-Like Receptor 4, Cytokine, medicine.anatomical_structure, Cytokines, Interleukin 19, Female, Synovial membrane

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3c380e4b71d08ae5765eeb87683ac4
https://doi.org/10.1002/art.20219

المؤلفون: Koichi Amano, C.S. Karyekar, Shoichi Uchimura, Teruaki Nakano, Mitsuhiro Iwahashi, Akira Yamazaki, Tsutomu Takeuchi, Toshihisa Kanamono, Hiroshi Inoue, Takaaki Tanaka, Tsukasa Matsubara, Tomomaro Izumihara

المصدر: Modern rheumatology. 25(5)

مصطلحات موضوعية: musculoskeletal diseases, Adult, Male, medicine.medical_specialty, Immunoconjugates, Injections, Subcutaneous, Pharmacology, Gastroenterology, Drug Administration Schedule, Disease activity, Abatacept, Arthritis, Rheumatoid, Rheumatology, Double-Blind Method, Internal medicine, medicine, Humans, Aged, biology, business.industry, Immunogenicity, C-reactive protein, Middle Aged, medicine.disease, C-Reactive Protein, Methotrexate, Treatment Outcome, Rheumatoid arthritis, Antirheumatic Agents, Retreatment, biology.protein, Drug Therapy, Combination, Female, Long term safety, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85bdf65aefccc9f3ca0c19cf24eaba8
https://pubmed.ncbi.nlm.nih.gov/25698370

المؤلفون: Akira Yamazaki, Koichi Amano, Shoichi Uchimura, Tomomaro Izumihara, Hiroshi Inoue, Toshihisa Kanamono, Takaaki Tanaka, Tsukasa Matsubara, Mitsuhiro Iwahashi, Tsutomu Takeuchi, Teruaki Nakano, C.S. Karyekar

المصدر: Modern rheumatology. 24(6)

مصطلحات موضوعية: musculoskeletal diseases, Adult, Male, medicine.medical_specialty, Immunoconjugates, Injections, Subcutaneous, Pharmacology, Gastroenterology, Antibodies, Drug Administration Schedule, law.invention, Abatacept, Arthritis, Rheumatoid, Subcutaneous injection, Rheumatology, Randomized controlled trial, Pharmacokinetics, Double-Blind Method, Japan, law, Internal medicine, medicine, Clinical endpoint, Humans, skin and connective tissue diseases, Aged, business.industry, Middle Aged, medicine.disease, Methotrexate, Treatment Outcome, Rheumatoid arthritis, Antirheumatic Agents, Injections, Intravenous, Retreatment, Female, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29788fb9e11838452abac075f7f14e9d
https://pubmed.ncbi.nlm.nih.gov/24708204