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1Academic Journal
المؤلفون: Timo K van den Berg, Hugo Olsman, Hanke L Matlung, Katka Franke, Imke Lodewijks, Lilian Driessen-Engels, Mary J van Helden, Seline A Zwarthoff, Roel J Arends, Inge M J Reinieren-Beeren, Marc C B C Paradé, Karin de Laat-Arts, Désirée Damming, Ellen W H Santegoeds-Lenssen, Daphne W J van Kuppeveld, Ellen Mattaar-Hepp, Marloes E M Stokman, Benny de Wit, Dirk H R F Glaudemans, Daniëlle E J W van Wijk, Lonnie Joosten-Stoffels, Jan Schouten, Paul J Boersema, Monique van der Vleuten, Jorien W H Sanderink, Wendela A Kappers, Diels van den Dobbelsteen, Marco Timmers, Ruud Ubink, Gerard J A Rouwendal, Gijs Verheijden, Miranda M C van der Lee, Wim H A Dokter
المصدر: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)
مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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المؤلفون: Bas P. A. Kokke, C. Marco Timmers, Henri Johannes Spijker, Jan Schouten, Pascal Renart Verkerk, Wim H. A. Dokter, Ruud Coumans, Patrick G. Groothuis, Ruud Ubink, Patrick Henry Beusker, Miranda M. C. van der Lee, Gerry J. A. Ariaans, Marion Blomenrohr
المصدر: Bioconjugate chemistry. 31(9)
مصطلحات موضوعية: Drug, Models, Molecular, Immunoconjugates, media_common.quotation_subject, Biomedical Engineering, Pharmaceutical Science, Bioengineering, 02 engineering and technology, Computational biology, 01 natural sciences, Duocarmycins, Mice, Therapeutic index, Cell Line, Tumor, Neoplasms, Animals, Humans, Cysteine, media_common, Pharmacology, Antibiotics, Antineoplastic, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, body regions, Specific antibody, ComputingMethodologies_PATTERNRECOGNITION, Immunoglobulin G, biology.protein, Antibody, 0210 nano-technology, Hydrophobic and Hydrophilic Interactions, Oxidation-Reduction, Biotechnology, Conjugate
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المؤلفون: Paolo Conti, Martin J. Smit, Rob Leurs, Douglas S. Auld, Petra de Kruijf, Martine J. Smit, Leontien Bosch, Miranda M. C. van der Lee, Jane van Heteren, Jac C. H. M. Wijkmans, G.J.R. Zaman, Herman D. Lim, Koc-Kan Ho, Michael Ohlmeyer
المساهمون: Medicinal chemistry
المصدر: de Kruijf, P, van Heteren, J T, Lim, H D, Conti, P, van der Lee, M M, Bosch, L, Ho, K K, Auld, D S, Ohlmeyer, M, Smit, M J, Wijkmans, J C, Zaman, G J & Leurs, R 2009, ' Nonpeptidergic allosteric antagonists differentially bind to the CXCR2 chemokine receptor ', The Journal of Pharmacology and Experimental Therapeutics, vol. 329, no. 2, pp. 783-90 . https://doi.org/10.1124/jpet.108.148387
The Journal of Pharmacology and Experimental Therapeutics, 329(2), 783-90. American Society for Pharmacology and Experimental Therapeuticsمصطلحات موضوعية: musculoskeletal diseases, Allosteric regulation, Plasma protein binding, Pharmacology, Transfection, Binding, Competitive, Receptors, Interleukin-8B, Chemokine receptor, Radioligand Assay, Structure-Activity Relationship, SDG 3 - Good Health and Well-being, Chlorocebus aethiops, Radioligand, Animals, Humans, CXC chemokine receptors, Binding site, Receptor, Chemistry, Phenylurea Compounds, hemic and immune systems, respiratory system, biological factors, respiratory tract diseases, COS Cells, Molecular Medicine, Allosteric Site, Protein Binding
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المؤلفون: Johan van der Vlag, Tracy M. Handel, Miranda M. C. van der Lee, Martine J. Smit, Joshua J. Ziarek, Guido J.R. Zaman, Henry F. Vischer, David C. Aguilar, Folkert Verkaar, Anne O. Watts, Jody van Offenbeek, Brian F. Volkman, Angelique L.W.M.M. Rops, Lambertus H. C. J. van Lith, Amanda E. I. Proudfoot
المساهمون: Medicinal chemistry, AIMMS
المصدر: Journal of Immunology. American Association of Immunologists
Verkaar, F, van Offenbeek, J, van der Lee, M M, Lith, L H, Watts, A O, Rops, A L, Aguilar, D C, Ziarek, J J, van der Vlag, J, Handel, T M, Volkman, B F, Proudfoot, A E, Vischer, H F, Zaman, G J & Smit, M J 2014, ' Chemokine cooperativity is caused by competitive glycosaminoglycan binding. ', Journal of Immunology . https://doi.org/10.4049/jimmunol.1302159
Journal of Immunology, 192, 3908-14
Journal of Immunology, 192, 8, pp. 3908-14مصطلحات موضوعية: CCR1, Immunology, CHO Cells, C-C chemokine receptor type 6, Biology, CCL7, Binding, Competitive, Models, Biological, Article, Chemokine receptor, Cricetulus, Cricetinae, Animals, Immunology and Allergy, CCL13, Glycosaminoglycans, Chemokine CCL21, Chemotaxis, SDG 10 - Reduced Inequalities, Chemokine CXCL13, CXCL2, Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], Biochemistry, Chemokine CCL19, XCL2, Receptors, Chemokine, Chemokines, Protein Multimerization, Protein Binding, CCL21
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المؤلفون: Claudia A. W. Timmerman, Martine J. Smit, Martien Kuijer, Jody van Offenbeek, Folkert Verkaar, Lambertus H. C. J. van Lith, Anne O. Watts, Guido J.R. Zaman, Henry F. Vischer, Miranda M. C. van der Lee, Rob Leurs
المساهمون: Medicinal chemistry, AIMMS
المصدر: Watts, A O, Verkaar, F, van der Lee, M M C, Timmerman, C A W, Kuijer, M, van Offenbeek, J, van Lith, L H J C, Smit, M J, Leurs, R, Zaman, G J R & Vischer, H F 2013, ' β-Arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR ', Journal of Biological Chemistry, vol. 288, no. 10, pp. 7169-7181 . https://doi.org/10.1074/jbc.M112.406108
Journal of Biological Chemistry, 288(10), 7169-7181. American Society for Biochemistry and Molecular Biology Inc.مصطلحات موضوعية: CCR1, Arrestins, Blotting, Western, Green Fluorescent Proteins, CCR3, C-C chemokine receptor type 7, CHO Cells, C-C chemokine receptor type 6, GTP-Binding Protein alpha Subunits, Gi-Go, Biology, environment and public health, Binding, Competitive, Models, Biological, Biochemistry, Receptors, CCR, Chemokine receptor, Cricetulus, SDG 3 - Good Health and Well-being, Cell Line, Tumor, Cricetinae, Heterotrimeric G protein, Animals, Humans, skin and connective tissue diseases, Molecular Biology, beta-Arrestins, Chemokine CCL21, Cell Biology, Molecular biology, biological factors, Cell biology, Protein Transport, HEK293 Cells, Microscopy, Fluorescence, Pertussis Toxin, Chemokines, CC, health occupations, Chemokine CCL19, Signal transduction, Protein Binding, Signal Transduction, CCL21
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المؤلفون: Martijn Timmerman, Jody van Offenbeek, Jesse W.Y. Wat, Lonneke Voorneveld, Folkert Verkaar, G.J.R. Zaman, Lambertus H. C. J. van Lith, Miranda M. C. van der Lee
المصدر: Cellular signalling. 25(2)
مصطلحات موضوعية: endocrine system, medicine.medical_specialty, Arrestins, media_common.quotation_subject, Parathyroid hormone, CHO Cells, Cell Line, Mice, Cricetulus, Internal medicine, Cricetinae, medicine, Arrestin, Cyclic AMP, Animals, Humans, Phosphorylation, Receptor, Internalization, beta-Arrestins, G protein-coupled receptor, media_common, Receptor, Parathyroid Hormone, Type 1, Calcium metabolism, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Chemistry, Parathyroid hormone receptor, Beta-Arrestins, Cell Biology, Endocrinology, Parathyroid Hormone, Calcium, hormones, hormone substitutes, and hormone antagonists, Signal Transduction
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المؤلفون: Jesse W.Y. Wat, Niels Smits, Antoon A. van der Doelen, Marion Blomenröhr, Miranda M. C. van der Lee, Guido J.R. Zaman, Chris J. van Koppen, Bonnie J. Hanson
المصدر: Journal of biomolecular screening. 14(7)
مصطلحات موضوعية: Cannabinoid receptor, Arrestins, medicine.medical_treatment, Morpholines, Biology, GTP-Binding Protein alpha Subunits, Gi-Go, Naphthalenes, Ligands, Biochemistry, Partial agonist, Analytical Chemistry, Imaging, Three-Dimensional, Receptor, Cannabinoid, CB1, Genes, Reporter, Cell Line, Tumor, Cannabinoid receptor type 2, medicine, Enzyme-linked receptor, Inverse agonist, Humans, Luciferases, beta-Arrestins, Cannabinoid Receptor Agonists, Cyclohexanols, Endocytosis, Benzoxazines, Pertussis Toxin, Molecular Medicine, GPR18, Biological Assay, Cannabinoid, Biotechnology