المؤلفون: Kai-Cheng Hsu, Hui-Chen Hung, Jim-Tong Horng, Ming-Yu Fang, Chun-Yu Chang, Ling-Ting Li, I-Jung Chen, Yun-Chu Chen, Ding-Li Chou, Chun-Wei Chang, Hsing-Pang Hsieh, Jinn-Moon Yang, John T-A Hsu

المصدر: PLoS ONE, Vol 19, Iss 11, p e0314066 (2024)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d1b92888065d4e17a07df3b60460138c

المؤلفون: Chen-Fu Lo, Tai-Yu Chiu, Yu-Tzu Liu, Li-Rung Huang, Teng-Kuang Yeh, Kuan-Hsun Huang, Kuan-Liang Liu, Chia-Yu Hsu, Ming-Yu Fang, Yu-Chen Huang, Tsu-An Hsu, Chiung-Tong Chen, Lun Kelvin Tsou

المصدر: Pharmaceutics; Volume 14; Issue 7; Pages: 1316

مصطلحات موضوعية: small molecule drug conjugates, zinc(II)-dipicolylamine, phosphatidylserine, thioester, maytansinoids

وصف الملف: application/pdf

Relation: Drug Delivery and Controlled Release; https://dx.doi.org/10.3390/pharmaceutics14071316

الاتاحة: https://doi.org/10.3390/pharmaceutics14071316

المؤلفون: Ming-Yu Fang, Kuan-Hsun Huang, Wei-Ju Tu, Yi-Ting Chen, Pei-Yun Pan, Wan-Chi Hsiao, Yi-Yu Ke, Lun K. Tsou, Mingzi M. Zhang

المصدر: Redox Biology, Vol 46, Iss , Pp 102126- (2021)

مصطلحات موضوعية: Nitroalkene fatty acid, Nitro-oleate, Michael addition, Nitro-alkylation, Macrophage, Click chemistry, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231721002858; https://doaj.org/toc/2213-2317

URL الوصول: https://doaj.org/article/07ddefb9cb444550933900ccaf1114fd

المؤلفون: Chen-Fu Lo, Tai-Yu Chiu, Yu-Tzu Liu, Pei-Yun Pan, Kuan-Liang Liu, Chia-Yu Hsu, Ming-Yu Fang, Yu-Chen Huang, Teng-Kuang Yeh, Tsu-An Hsu, Chiung-Tong Chen, Li-Rung Huang, Lun Kelvin Tsou

المصدر: Journal of Medicinal Chemistry. 65:12802-12824

مصطلحات موضوعية: Drug Discovery, Tumor Microenvironment, Humans, Molecular Medicine, Triple Negative Breast Neoplasms, Phosphatidylserines, RNA, Messenger, Sorafenib, Ligands

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bb404edb1977851cd5399c93a029856
https://doi.org/10.1021/acs.jmedchem.2c00631

المؤلفون: Pei-Yun Pan, Wei-Ju Tu, Yi-Ting Chen, Lun K. Tsou, Wan-Chi Hsiao, Ming-Yu Fang, Mingzi M. Zhang, Kuan-Hsun Huang, Yi-Yu Ke

المصدر: Redox Biology, Vol 46, Iss, Pp 102126-(2021)
Redox Biology

مصطلحات موضوعية: Cell signaling, Medicine (General), Alkylation, Macrophage, QH301-705.5, Clinical Biochemistry, Biochemistry, Nitro-oleate, Glucocorticoid receptor, R5-920, Michael addition, Animals, Biology (General), Receptor, Nitroalkene fatty acid, Retinoid X receptor alpha, Chemistry, Click chemistry, Endoplasmic reticulum, Fatty Acids, Organic Chemistry, Lipid metabolism, Lipid signaling, Nitro Compounds, Transmembrane protein, Nitro-alkylation, Research Paper, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e59a01e813f206c3e9f886a19375cbc7
http://www.sciencedirect.com/science/article/pii/S2213231721002858

المؤلفون: Mingzi M. Zhang, Ming-Yu Fang, Pei-Yun Pan, Yi-Yu Ke, Yi-Ting Chen, Lun K. Tsou, Wan-Chi Hsiao, Wei-Ju Tu, Kuan-Hsun Huang

مصطلحات موضوعية: Cell signaling, Glucocorticoid receptor, Biochemistry, Retinoid X receptor alpha, Chemistry, Endoplasmic reticulum, Lipid metabolism, Lipid signaling, Receptor, Transmembrane protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1af845a504f52ad0e75f69d2ef6cbf6e
https://doi.org/10.1101/2021.07.12.451990

المؤلفون: Hui-Chen Hung, Shin-Ru Shih, Teng-Yuan Chang, Ming-Yu Fang, John T-A Hsu

المصدر: PLoS ONE, Vol 9, Iss 11, p e111331 (2014)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4239034?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/d26b2c67c7094cff9f0b895be2170a24

المؤلفون: Kai-Cheng Hsu, Hui-Chen Hung, Jim-Tong Horng, Ming-Yu Fang, Chun-Yu Chang, Ling-Ting Li, I-Jung Chen, Yun-Chu Chen, Ding-Li Chou, Chun-Wei Chang, Hsing-Pang Hsieh, Jinn-Moon Yang, John T-A Hsu

المصدر: PLoS ONE, Vol 8, Iss 2, p e56704 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3577712?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/268a59ab9838414a85c0be9a37a85296

المؤلفون: Kak-Shan Shia, Wei-Han Chen, Jiing-Jyh Jan, Chien-Huang Wu, Lun K. Tsou, Teng-Kuang Yeh, Yu-Wei Liu, Chen-Fu Lo, Kuan-Liang Liu, Koon Y. Pak, Chen-Lung Huang, Ming-Yu Fang, Tsu-An Hsu, Yu-Chen Huang, Yun-Yu Chen, Chiung-Tong Chen, Yu‐Cheng Yeh, Kuan-Hsun Huang, Brian D. Gray

المصدر: Bioconjugate chemistry. 28(7)

مصطلحات موضوعية: 0301 basic medicine, Drug, Immunoconjugates, media_common.quotation_subject, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Antineoplastic Agents, Phosphatidylserines, Pharmacology, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Pharmacokinetics, In vivo, Cell Line, Tumor, medicine, Organometallic Compounds, Animals, Humans, Molecular Targeted Therapy, Picolinic Acids, media_common, Organic Chemistry, Phosphatidylserine, Small molecule, Xenograft Model Antitumor Assays, Irinotecan, 030104 developmental biology, chemistry, Dipicolylamine, 030220 oncology & carcinogenesis, Biotechnology, medicine.drug, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2f7d9d7a6d3c9504420311bec993b3
https://pubmed.ncbi.nlm.nih.gov/28581724

المؤلفون: Sing Yi Wang, Yi-Rong Chen, Ming Yu Fang, Shaik Rafi, Wen-Hsing Lin, Mohane Selvaraj Coumar, Yu-Sheng Chao, John T.A. Hsu, Teng Yuan Chang, Hsing Pang Hsieh, Kai-Chia Yeh, Ching Ping Chen, Chiung-Tong Chen, Chang Ying Chu, Hui Hsu, Chun-Chen Liao, Chun Hwa Chen, Su Huei Hsieh, Tzu Wen Lien, Hui Yi Shiao, Chia Hsien Wu, Teng Kuang Yeh, Chun Yu Chang

المصدر: Journal of Medicinal Chemistry. 53:7316-7326

مصطلحات موضوعية: Male, Transplantation, Heterologous, Mice, Nude, Antineoplastic Agents, Rats, Sprague-Dawley, Mice, Structure-Activity Relationship, T790M, Gefitinib, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, medicine, Side chain, Animals, Humans, Structure–activity relationship, Epidermal growth factor receptor, biology, Chemistry, Kinase, Stereoisomerism, Orders of magnitude (mass), Rats, respiratory tract diseases, ErbB Receptors, Transplantation, Pyrimidines, Biochemistry, Drug Resistance, Neoplasm, Drug Design, Mutation, Quinazolines, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor, Heterocyclic Compounds, 3-Ring, Neoplasm Transplantation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2314351e3bb3abdcd896ccecee8f0760
https://doi.org/10.1021/jm100607r

المؤلفون: John T.A. Hsu, Ming-Yu Fang, Kuei-Jung Yen, Tzu-Chun Chen, Shin-Ru Shih, Ching-Ping Tseng, Hui-Chen Hung

المصدر: Journal of Antimicrobial Chemotherapy

مصطلحات موضوعية: Microbiology (medical), Viral Plaque Assay, viruses, RNA-dependent RNA polymerase, polyanionic compounds, Biology, Virus Replication, Antiviral Agents, enteroviruses, chemistry.chemical_compound, Viral Proteins, Cytopathogenic Effect, Viral, Viral entry, Cell Line, Tumor, Aurintricarboxylic acid, Chlorocebus aethiops, Animals, Humans, Pharmacology (medical), Enzyme Inhibitors, Vero Cells, Cytopathic effect, Original Research, Pharmacology, Virus quantification, Aurintricarboxylic Acid, Proteolytic enzymes, RNA-Dependent RNA Polymerase, Virology, Molecular biology, Enterovirus A, Human, Infectious Diseases, Viral replication, chemistry, COS Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e615f0ebf21a3d7f75ce8a05c5a2ba4
http://europepmc.org/articles/PMC7110181

المؤلفون: Shin-Ru Shih, John T.A. Hsu, Hui-Chen Hung, Ming-Yu Fang, Teng-Yuan Chang

المصدر: PLoS ONE, Vol 9, Iss 11, p e111331 (2014)
PLoS ONE

مصطلحات موضوعية: Toluidines, Antiviral Therapeutics, Hydroxybutyrates, lcsh:Medicine, Apoptosis, Pharmacology, Virus Replication, Antiviral Agents, Microbiology, Virus Effects on Host Gene Expression, Cell Line, Proinflammatory cytokine, Virology, Emerging Viral Diseases, Chlorocebus aethiops, Nitriles, Enterovirus Infections, medicine, Animals, Humans, Interleukin 6, lcsh:Science, Vero Cells, Leflunomide, Neurotropic virus, Aniline Compounds, Multidisciplinary, biology, business.industry, lcsh:R, Drug Repositioning, Biology and Life Sciences, Drug Synergism, Viral Replication, Enterovirus A, Human, Drug repositioning, Viral replication, Cell culture, Crotonates, biology.protein, Cytokines, Drug Therapy, Combination, lcsh:Q, Lithium Chloride, business, Research Article, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d6b76581553b9ff7f62e1be9e26fb9d
http://europepmc.org/articles/PMC4239034?pdf=render

المؤلفون: Hui Chen Hung, Kwok-Kong Tony Mong, Ming Yu Fang, Tsu An Hsu, Anindya Das, Mark von Itzstein, Tsung Che Chang, Chien Hung Lin, Chun-Cheng Lin, Jinn-Moon Yang, Kai Cheng Hsu

المصدر: Organicbiomolecular chemistry. 11(24)

مصطلحات موضوعية: viruses, Substituent, Neuraminidase, Microbial Sensitivity Tests, Biochemistry, Antiviral Agents, chemistry.chemical_compound, Structure-Activity Relationship, Zanamivir, Influenza A Virus, H1N1 Subtype, medicine, Structure–activity relationship, Physical and Theoretical Chemistry, Enzyme Inhibitors, Guanidine, IC50, biology, Dose-Response Relationship, Drug, Molecular Structure, Influenza A Virus, H3N2 Subtype, Organic Chemistry, virus diseases, biochemical phenomena, metabolism, and nutrition, Combinatorial chemistry, respiratory tract diseases, chemistry, biology.protein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9fa914e7a68d9db9111f073497c0586
https://pubmed.ncbi.nlm.nih.gov/23695381

المؤلفون: John T.A. Hsu, Chun-Yu Chang, Jim-Tong Horng, Hui-Chen Hung, Ding-Li Chou, Ming-Yu Fang, Chun Wei Chang, I-Jung Chen, Ling-Ting Li, Yun-Chu Chen, Jinn-Moon Yang, Kai-Cheng Hsu, Hsing Pang Hsieh

المصدر: PLoS ONE
PLoS ONE, Vol 8, Iss 2, p e56704 (2013)

مصطلحات موضوعية: Viral Diseases, Genotype, Mutant, lcsh:Medicine, Neuraminidase, Anthraquinones, medicine.disease_cause, Biochemistry, Microbiology, Antiviral Agents, Virus, Protein structure, Influenza A Virus, H1N1 Subtype, Virology, Drug Discovery, Drug Resistance, Viral, Influenza, Human, Influenza A virus, medicine, Humans, lcsh:Science, Biology, Pandemics, Mutation, Multidisciplinary, biology, lcsh:R, Wild type, Proteins, Computational Biology, Influenza, Drug Resistance, Multiple, Multiple drug resistance, Infectious Diseases, Small Molecules, biology.protein, Medicine, lcsh:Q, Research Article, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3311300ac4c73f49693094c656dd7b93
http://europepmc.org/articles/PMC3577712

المؤلفون: Hsing Pang Hsieh, Fu Ming Kuo, Ming Yu Fang, Teng Kuang Yeh, Jim-Tong Horng, Ta Jen Lin, Shengkai Ko, Mohane Selvaraj Coumar, Shin-Ru Shih, Hui Chen Hung, Yu-Sheng Chao, Yen Chun Lee, Yu Lin Huang, Hui Yi Shiao, John T.A. Hsu, Jiann Yih Yeh

المصدر: ChemMedChem. 7(9)

مصطلحات موضوعية: Male, Pharmacology, Biochemistry, Antiviral Agents, Cell Line, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Influenza A Virus, H1N1 Subtype, Pharmacokinetics, Orthomyxoviridae Infections, Drug Discovery, Influenza, Human, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Drug discovery, Organic Chemistry, Quinoline, Lead Agent, Bioavailability, Rats, chemistry, Anti influenza drug, Quinolines, Molecular Medicine, Derivative (chemistry)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acede49520cce70e3e8b876f62807686
https://pubmed.ncbi.nlm.nih.gov/22821876

المؤلفون: Wen-Hsing, Lin, Jen-Shin, Song, Tzu-Wen, Lien, Chun-Yu, Chang, Szu-Huei, Wu, Yu-Wen, Huang, Teng-Yuan, Chang, Ming-Yu, Fang, Kuei-Jung, Yen, Chun-Hwa, Chen, Chang-Ying, Chu, Hsing-Pang, Hsieh, Yi-Rong, Chen, Yu-Sheng, Chao, John T-A, Hsu

المصدر: Anticancer research. 32(1)

مصطلحات موضوعية: Lung Neoplasms, Epidermal Growth Factor, Gefitinib, High-Throughput Screening Assays, ErbB Receptors, Drug Resistance, Neoplasm, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Mutation, Quinazolines, Humans, Phosphorylation, Protein Kinase Inhibitors, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::5ec6a1906bfbcd8cae17b0c31e0abdaf
https://pubmed.ncbi.nlm.nih.gov/22213300

المؤلفون: Jiann Yih Yeh, Hsing Pang Hsieh, John T.A. Hsu, Shengkai Ko, Kean Seng Lau, Chung-Fan Hsieh, Hui Chen Hung, Yao Chieh Chou, Ta Jen Lin, Jim-Tong Horng, Mei Ling Li, Wen Fang Tang, Ming Sian Wu, Ming Yu Fang

المصدر: Antimicrobial agents and chemotherapy. 56(2)

مصطلحات موضوعية: RNA Caps, Transcription, Genetic, viruses, Orthomyxoviridae, medicine.disease_cause, Virus Replication, Antiviral Agents, Virus, Cap snatching, Cell Line, Viral Proteins, Dogs, Influenza A Virus, H1N1 Subtype, Cytopathogenic Effect, Viral, Viral entry, Transcription (biology), Influenza A virus, medicine, Animals, Humans, Pharmacology (medical), Polymerase, Pharmacology, biology, Influenza A Virus, H3N2 Subtype, biology.organism_classification, Endonucleases, Virology, Molecular biology, Influenza B virus, Infectious Diseases, HEK293 Cells, Viral replication, biology.protein, Quinolines, Pyrazoles, RNA, Viral

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c099f4efbb9032e353af029f3ed4d8c
https://pubmed.ncbi.nlm.nih.gov/21930871

المؤلفون: Hsing Pang Hsieh, Yu-Sheng Chao, Tzu-Wen Lien, Jen-Shin Song, Yun-Lung Ho, Ming-Yu Fang, Wen-Hsing Lin, Chun-Chen Liao, John T.A. Hsu, Chang-Ying Chu, Cheng-Wei Lin, Jiun-Shyang Leou, Szu-Huei Wu, Santhosh Kumar Chittimalla, Chin-Ting Huang, Randheer Reddy, Chun-Hwa Chen, Yi-Hui Peng, Jian-Sung Wu, Hui Yi Shiao, Su-Ying Wu, Mohane Selvaraj Coumar

المصدر: Journal of medicinal chemistry. 53(13)

مصطلحات موضوعية: Models, Molecular, Lung Neoplasms, Magnetic Resonance Spectroscopy, Cell Survival, Mutant, Blotting, Western, Aurora inhibitor, Antineoplastic Agents, Protein Serine-Threonine Kinases, Spectrometry, Mass, Fast Atom Bombardment, Crystallography, X-Ray, Inhibitory Concentration 50, Aurora Kinases, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Discovery, Humans, Epidermal growth factor receptor, Kinase activity, Furans, Protein Kinase Inhibitors, biology, Kinase, Chemistry, Hit to lead, Molecular biology, ErbB Receptors, Pyrimidines, Cell culture, Docking (molecular), Cancer research, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba2fd158eeddb8e8a6730aa550364dc
https://pubmed.ncbi.nlm.nih.gov/20550212

المؤلفون: Biing-Jiun Uang, Hsing Pang Hsieh, Ming Yu Fang, John T.A. Hsu, Chun Hwa Chen, Jian Sung Wu, Ming Tsung Tsai, Su Ying Wu, Wen-Hsing Lin, Chi Huang Teng, Chang Ying Chu, Yu-Sheng Chao, Teng Yuan Chang, Jiun Shyang Leou, Chun Yu Chang, Mohane Selvaraj Coumar

المصدر: ChemMedChem. 5(2)

مصطلحات موضوعية: Hydrazone, Biology, Protein Serine-Threonine Kinases, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, Structure-Activity Relationship, Aurora kinase, Aurora Kinases, Drug Discovery, Transferase, General Pharmacology, Toxicology and Pharmaceutics, Furans, Protein Kinase Inhibitors, Pharmacology, chemistry.chemical_classification, Binding Sites, Kinase, Organic Chemistry, Combinatorial chemistry, High-Throughput Screening Assays, Library collection, Pyrimidines, Structural biology, chemistry, Molecular Medicine, Aurora Kinase A, Derivative (chemistry), Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed68da99234a4a00105a8a7a19a62440
https://pubmed.ncbi.nlm.nih.gov/20039358

المؤلفون: Yu-Ning Fu, Teng-Yuan Chang, Ming-Yu Fang, Lin-Mei Wang, Jen-Shin Song, Wen-Hsing Lin, Yu-Wen Huang, Chun-Yu Chang, Yu-Sheng Chao, Tzu-Wen Lien, Shiu-Feng Huang, Shih-Feng Tsai, Szu-Huei Wu, Yi-Rong Chen, Chi-Ling Yeh, John T.A. Hsu, Hsing Pang Hsieh

المصدر: Analytical biochemistry. 377(1)

مصطلحات موضوعية: Cell Survival, Cell, Biophysics, Drug Evaluation, Preclinical, Biochemistry, Cell Line, Mice, Epidermal growth factor, medicine, Animals, Humans, ERBB3, Epidermal growth factor receptor, Kinase activity, Phosphorylation, Molecular Biology, Protein Kinase Inhibitors, biology, Cell growth, Chemistry, Reproducibility of Results, Cell Biology, Cell biology, Enzyme Activation, ErbB Receptors, medicine.anatomical_structure, biology.protein, Cyclin-dependent kinase 8, A431 cells, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8c53b5cf4bbdb5f54e114e1b7bf73a0
https://pubmed.ncbi.nlm.nih.gov/18358823