المؤلفون: Tonko Dražić (3703870), Nikos Kühl (10996734), Mila M. Leuthold (6195185), Mira A. M. Behnam (9128698), Christian D. Klein (1456204)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences not elsewhere classified, biochemical protease assay, SARS-CoV-2, main protease, FRET substrate

Relation: https://figshare.com/articles/journal_contribution/sj-pdf-1-jbx-10_1177_24725552211020681_Supplemental_material_for_Efficiency_Improvements_and_Discovery_of_New_Substrates_for_a_SARS-CoV-2_Main_Protease_FRET_Assay/14812305

الاتاحة: https://doi.org/10.25384/sage.14812305.v1

المؤلفون: Nikos Kühl (9128695), Mila M. Leuthold (6195185), Mira A. M. Behnam (9128698), Christian D. Klein (1456204)

مصطلحات موضوعية: Biochemistry, Pharmacology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, off-target interactions, replication assays, drug discovery, novel benzamide derivatives, pharmacokinetic liabilities, host proteases, serine protease NS 2B, active-site-directed flaviviral pro., submicromolar activities, EC, off-target proteases, dengue virus, Potent Activity, Cell Culture, flaviviral proteases, recognition preferences, small-molecular inhibitors, protease favor, DENV 2proHeLa system, reporter gene assay, dengue protease

Relation: https://figshare.com/articles/journal_contribution/Beyond_Basicity_Discovery_of_Nonbasic_DENV_2_Protease_Inhibitors_with_Potent_Activity_in_Cell_Culture/14414659

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02042.s002

المؤلفون: Nikos Kühl (9128695), Mila M. Leuthold (6195185), Mira A. M. Behnam (9128698), Christian D. Klein (1456204)

مصطلحات موضوعية: Biochemistry, Pharmacology, Infectious Diseases, Plant Biology, Virology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, off-target interactions, replication assays, drug discovery, novel benzamide derivatives, pharmacokinetic liabilities, host proteases, serine protease NS 2B, active-site-directed flaviviral pro., submicromolar activities, EC, off-target proteases, dengue virus, Potent Activity, Cell Culture, flaviviral proteases, recognition preferences, small-molecular inhibitors, protease favor, DENV 2proHeLa system, reporter gene assay, dengue protease

Relation: https://figshare.com/articles/dataset/Beyond_Basicity_Discovery_of_Nonbasic_DENV_2_Protease_Inhibitors_with_Potent_Activity_in_Cell_Culture/14414656

الاتاحة: https://doi.org/10.1021/acs.jmedchem.0c02042.s001