المؤلفون: Behnam Nabet, Fleur M. Ferguson, Bo Kyung A. Seong, Miljan Kuljanin, Alan L. Leggett, Mikaela L. Mohardt, Amanda Robichaud, Amy S. Conway, Dennis L. Buckley, Joseph D. Mancias, James E. Bradner, Kimberly Stegmaier, Nathanael S. Gray

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/459b2972ed404c94bc46191739350a3c

المؤلفون: David A. Scott, Ke Peng, Eriko Koide, Nathanael S. Gray, Brian J. Groendyke, Behnam Nabet, Adam J. Bass, Calvin R Coffey, Jianwei Che, Mikaela L. Mohardt, Haisheng Zhang

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: 010405 organic chemistry, Angiogenesis, Chemistry, Kinase, Organic Chemistry, 01 natural sciences, Biochemistry, Small molecule, 0104 chemical sciences, Focal adhesion, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, Aminothiazole, Drug Discovery, Cancer research, Kinome, Tyrosine kinase, Lead compound

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ebae3947d6c906cbef22e4b961ed0fb
https://doi.org/10.1021/acsmedchemlett.0c00338

المؤلفون: Amanda L. Robichaud, Mikaela L. Mohardt, Fleur M. Ferguson, Behnam Nabet, Joseph D. Mancias, James E. Bradner, Amy Saur Conway, Alan L. Leggett, Dennis L. Buckley, Nathanael S. Gray, Bo Kyung A. Seong, Miljan Kuljanin, Kimberly Stegmaier

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Nature Communications

مصطلحات موضوعية: Male, Proteomics, 0301 basic medicine, Science, Direct control, Chemical biology, General Physics and Astronomy, Tacrolimus Binding Protein 1A, Protein Homeostasis, 01 natural sciences, Article, General Biochemistry, Genetics and Molecular Biology, Target validation, Proto-Oncogene Proteins p21(ras), Tacrolimus Binding Proteins, Gene Knockout Techniques, Mice, 03 medical and health sciences, Mice, Inbred NOD, Animals, Humans, Molecule, lcsh:Science, Mice, Knockout, Protein function, Multidisciplinary, 010405 organic chemistry, Chemistry, HEK 293 cells, Proteins, General Chemistry, Small molecule, 0104 chemical sciences, Cell biology, Mice, Inbred C57BL, HEK293 Cells, 030104 developmental biology, Von Hippel-Lindau Tumor Suppressor Protein, Models, Animal, Proteolysis, Female, lcsh:Q, Target protein, Chemical tools, Peptide Hydrolases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c94cdbfd9c597da926943a6f6caa324
https://doaj.org/article/459b2972ed404c94bc46191739350a3c

المؤلفون: Kun Ping Lu, Hyuk-Soo Seo, Yujin Chun, Christopher M. Browne, Theresa D. Manz, Xiao Zhen Zhou, Zainab M. Doctor, Xiaolan Lian, Zoe C. Yeoh, Shin Kibe, Scott B. Ficarro, Nir London, Benika J. Pinch, Nicholas E. Vangos, Behnam Nabet, Stephen Buratowski, Dina Daitchman, Shingo Kozono, Daniel Zaidman, Nathanael S. Gray, Jarrod A. Marto, Mikaela L. Mohardt, Li Tan, Sirano Dhe-Paganon, Ezekiel A. Geffken

المصدر: Nature chemical biology

مصطلحات موضوعية: endocrine system diseases, Cell Survival, Protein Conformation, Mutant, Antineoplastic Agents, Crystallography, X-Ray, medicine.disease_cause, Article, Proto-Oncogene Proteins p21(ras), Mice, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, Cysteine, Viability assay, Enzyme Inhibitors, Molecular Biology, 030304 developmental biology, 0303 health sciences, Chemistry, 030302 biochemistry & molecular biology, HEK 293 cells, Cancer, Cell Biology, medicine.disease, digestive system diseases, Gene Expression Regulation, Neoplastic, NIMA-Interacting Peptidylprolyl Isomerase, Pancreatic Neoplasms, Cell Transformation, Neoplastic, HEK293 Cells, Cell culture, Drug Design, NIH 3T3 Cells, Cancer research, PIN1, KRAS, Carcinogenesis, Carcinoma, Pancreatic Ductal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6565cbd6de180dcf92ba1d74b5e545e0
https://doi.org/10.1038/s41589-020-0550-9