يعرض 1 - 20 نتائج من 154 نتيجة بحث عن '"Microcirculación]"', وقت الاستعلام: 0.70s تنقيح النتائج
  1. 1
    Dissertation/ Thesis

    المؤلفون: Sans Roselló, Jordi

    Thesis Advisors: Álvarez García, Jesús, Cinca, Juan

    المصدر: TDX (Tesis Doctorals en Xarxa)

    وصف الملف: application/pdf

  2. 2
    Dissertation/ Thesis

    المؤلفون: Claverias Cabrera, Laura

    المساهمون: University/Department: Universitat Rovira i Virgili. Departament de Medicina i Cirurgia

    Thesis Advisors: Rodríguez Oviedo, Alejandro Hugo

    المصدر: TDX (Tesis Doctorals en Xarxa)

    Time: 616.9

    وصف الملف: application/pdf

  3. 3
    Dissertation/ Thesis

    المؤلفون: Mesquida Febrer, Jaume

    المساهمون: University/Department: Universitat Autònoma de Barcelona. Departament de Medicina

    Thesis Advisors: Artigas Raventós, Antoni, Baigorri González, Francisco

    المصدر: TDX (Tesis Doctorals en Xarxa)

    وصف الملف: application/pdf

  4. 4
    Academic Journal

    المصدر: Revista Cubana de Investigaciones Biomédicas; Vol. 43 (2024): Publicación continua ; 1561-3011 ; 0864-0300

    وصف الملف: application/pdf

    Relation: https://revibiomedica.sld.cu/index.php/ibi/article/view/2968/1614; Camici PG, Crea F. Coronary microvascular dysfunction. N Engl J Med. 2007;356(8):830-40. DOI: https://doi.org/10.1056/NEJMra061889 2. Escaned J, Flores A, García P, Segovia J, Jimenez J, Aragoncillo P, et al. Assessment of microcirculatory remodeling with intracoronary flow velocity and pressure measurements: Validation with endomyocardial sampling in cardiac allografts. Circulation. 2009;120(16):1561-8. DOI: https://doi.org/10.1161/CIRCULATIONAHA.108.834739 3. Kaski JC, Crea F, Gersh BJ, Camici PG. Reappraisal of ischemic heart disease: Fundamental role of coronary microvascular dysfunction in the pathogenesis of angina pectoris. Circulation. 2018;138(14):1463-80. DOI: https://doi.org/10.1161/CIRCULATIONAHA.118.031373 4. Gould KL, Johnson NP. Coronary physiology beyond coronary flow reserve in microvascular angina: JACC state-of-the-art review. J Am Coll Cardiol. 2018;72(21):2642-62. DOI: https://doi.org/10.1016/j.jacc.2018.07.106 5. Kunadian V, Chieffo A, Camici PG, Berry C, Escaned J, Maas AHEM, et al. An EAPCI Expert Consensus Document on Ischaemia with Non-Obstructive Coronary Arteries in collaboration with European Society of Cardiology Working Group on Coronary Pathophysiology&Microcirculation Endorsed by Coronary Vasomotor Disorders International Study Group. Eur Heart J. 2020;41(37):3504-20. DOI: https://doi.org/10.1093/eurheartj/ehaa503 6. Pries AR, Badimon L, Bugiardini R, Camici PG, Dorobantu M, Duncker DJ, et al. Coronary vascular regulation, remodelling, and collateralization: Mechanisms and clinical implications on behalf of the working group on coronary pathophysiology and microcirculation. Eur Heart J. 2015;36(45):3134-46. DOI: https://doi.org/10.1093/eurheartj/ehv100 7. Beltrame JF, Crea F, Kaski JC, Ogawa H, Ong P, Sechtem U, et al. International standardization of diagnostic criteria for vasospastic angina. Eur Heart J. 2017;38(33):2565-8. DOI: https://doi.org/10.1093/eurheartj/ehv351 8. Beltrame JF, Crea F, Camici P. Advances in coronary microvascular dysfunction. Heart Lung Circ. 2009;18(1):19-27. DOI: https://doi.org/10.1016/j.hlc.2008.11.002 9. Ludmer PL, Selwyn AP, Shook TL, Wayne RR, Mudge GH, Alexander RW, et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med. 1986;315(17):1046-51. DOI: https://doi.org/10.1056/nejm198610233151702 10. Fearon WF, Balsam LB, Farouque HM, Caffarelli AD, Robbins RC, Fitzgerald PJ, et al. Novel index for invasively assessing the coronary microcirculation. Circulation. 2003;107(25):3129-32. DOI: https://doi.org/10.1161/01.CIR.0000080700.98607.D1 11. Ng MK, Yeung AC, Fearon WF. Invasive assessment of the coronary microcirculation: superior reproducibility and less hemodynamic dependence of index of microcirculatory resistance compared with coronary flow reserve. Circulation. 2006;113(17):2054-61. DOI: https://doi.org/10.1161/CIRCULATIONAHA.105.603522 12. Aarnoudse W, van’t Veer M, Pijls NH, Ter Woorst J, Vercauteren S, Tonino P, et al. Direct volumetric blood flow measurement in coronary arteries by thermodilution. J Am Coll Cardiol. 2007;50(24):2294-2304. DOI: https://doi.org/10.1016/j.jacc.2007.08.047 13. Usui E, Murai T, Kanaji Y, Hoshino M, Yamaguchi M, Hada M, et al. Clinical significance of concordance or discordance between fractional flow reserve and coronary flow reserve for coronary physiological indices, microvascular resistance, and prognosis after elective percutaneous coronary intervention. EuroIntervention. 2018;14(7):798-805. DOI: https://doi.org/10.4244/eij-d-17-00449 14. Everaars H, de Waard GA, Driessen RS, Danad I, van de Ven PM, Raijmakers PG, et al. Doppler flow velocity and thermodilution to assess coronary flow reserve: a head-to-head comparison with [15O]H2O PET. JACC Cardiovasc Interv. 2018;11(20):2044-54. DOI: https://doi.org/10.1016/j.jcin.2018.07.011 15. Xaplanteris P, Fournier S, Keulards DCJ, Adjedj J, Ciccarelli G, Milkas A, et al. Catheter-based measurements of absolute coronary blood flow and microvascular resistance: feasibility, safety, and reproducibility in humans. Circ Cardiovasc Interv. 2018;11(3). DOI: https://doi.org/10.1161/CIRCINTERVENTIONS.117.006194 16. De Bruyne B, Adjedj J, Xaplanteris P, Ferrara A, Mo Y, Penicka M, et al. Saline-induced coronary hyperemia: mechanisms and effects on left ventricular function. Circ Cardiovasc Interv. 2017;10(4). DOI: https://doi.org/10.1161/CIRCINTERVENTIONS.116.004719 17. Everaars H, Waard G, Schumacher S, Zimmermann F, Bom M, van de Ven P, et al. Continuous infusion of saline for assessment of absolute hyperemic flow and minimal microvascular resistance: validation in humans using [15O]H2O PET. Europ Heart J. 2019;40(28):2350-9. DOI: https://doi.org/10.1093/eurheartj/ehz245 18. Keulards DCJ, Fournier S, van ’t Veer M, Colaiori I, Zelis JM, El Farissi M, et al. Computed tomographic myocardial mass compared with invasive myocardial perfusion measurement. Heart. 2020;106(19):1489-94. DOI: https://doi.org/10.1136/heartjnl-2020-316689 19. Ihdayhid AR, Sellers SL. Novel method for assessing myocardium at risk: a new arrow in the diagnostic quiver of coronary CT. Heart. 2020;106(19):1458-60. DOI: https://doi.org/10.1136/heartjnl-2020-317155 20. De Bruyne B, Pijls NHJ, Gallinoro E, Candreva A, Fournier S, Keulards DCJ, et al. Microvascular resistance reserve for assessment of coronary microvascular function: JACC Technology Corner. J Am Coll Cardiol. 2021;78(15):1541-9. DOI: https://doi.org/10.1016/j.jacc.2021.08.017 21. Koo BK, Erglis A, Doh JH, Daniels DV, Jegere S, Kim HS, et al. Diagnosis of ischaemia-causing coronary stenoses by noninvasive Fractional Flow Reserve computed from coronary computed tomographic angiograms results from the prospective multicenter DISCOVERFLOW (Diagnosis of ischaemia-causing stenoses obtained via noninvasive Fractional Flow Reserve) Study. J Am Coll Cardiol. 2011;58(19):1989-97. DOI: https://doi.org/10.1016/j.jacc.2011.06.066 22. Douglas PS, Pontone G, Hlatky MA, Patel MR, Norgaard BL, Byrne RA, et al. Clinical outcomes of fractional flow reserve by computed tomographic angiography-guided diagnostic strategies vs. usual care in patients with suspected coronary artery disease: the prospective longitudinal trial of FFR(CT): outcome and resource impacts study. Eur Heart J. 2015;368(47):3359-67. DOI: https://doi.org/10.1093/eurheartj/ehv444 23. Van Hinsbergh VW. Endothelial permeability for macromolecules. Mechanistic aspects of pathophysiological modulation. Arterioscler Thromb Vasc Biol. 1997;17(6):1018-23. DOI: https://doi.org/10.1161/01.atv.17.6.1018 24. Chatzizisis YS, Coskun AU, Jonas M, Edelman ER, Feldman CL, Stone PH. Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior. J Am Coll Cardiol. 2007;49(25):2379-93. DOI: https://doi.org/10.1016/j.jacc.2007.02.059 25. Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci U S A. 1987;84(24):9265-9. DOI: https://doi.org/10.1073/pnas.84.24.9265 26. Rodriguez EA. GATA2 promotes human vascular smooth muscle cell proliferation via mitofusin2- mediated Ras/Raf/MEK/ERK signaling pathway. New target in vascular medicine. Int J Cardiol. 2022;353:86-7. DOI: https://doi.org/10.1016/j.ijcard.2022.01.062 27. Anderson EA, Mark AL. Flow-mediated and reflex changes in large peripheral artery tone in humans. Circulation. 1989;79(1):93-100. DOI: https://doi.org/10.1161/01.cir.79.1.93 28. Rubanyi GM, Romero JC, Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol. 1986;250(6):H1145-9. DOI: https://doi.org/10.1152/ajpheart.1986.250.6.h1145 29. Koller A, Kaley G. Prostaglandins mediate arteriolar dilation to increased blood flow velocity in skeletal muscle microcirculation. Circ Res. 1990;67(2):529-34. DOI: https://doi.org/10.1161/01.res.67.2.529 30. Okahara K, Sun B, Kambayashi J. Upregulation of prostacyclin synthesis-related gene expression by shear stress in vascular endothelial cells. Arterioscler Thromb Vasc Biol. 1998;18(12):1922-6. DOI: https://doi.org/10.1161/01.atv.18.12.1922 31. Pohl U, Holtz J, Busse R, Bassenge E. Crucial role of endothelium in the vasodilator response to increased flow in vivo. Hypertension. 1986;8(1):37-44. DOI: https://doi.org/10.1161/01.hyp.8.1.37 32. Joannides R, Haefeli WE, Linder L, Richard V, Bakkalli EH, Thuillez C, et al. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation. 1995;91(5):1314-9. DOI: https://doi.org/10.1161/01.cir.91.5.1314 33. Taddei S, Ghiadoni L, Virdis A, Buralli S, Salvetti A. Vasodilation to bradykinin is mediated by an ouabain-sensitive pathway as a compensatory mechanism for impaired nitric oxide availability in essential hypertensive patients. Circulation. 1999;100(13):1400-5. DOI: https://doi.org/10.1161/01.cir.100.13.1400 34. Richard V, Tanner FC, Tschudi M, Luscher TF. Different activation of L-arginine pathway by bradykinin, serotonin, and clonidine in coronary arteries. Am J Physiol. 1990;259(5):H1433-9. DOI: https://doi.org/10.1152/ajpheart.1990.259.5.h1433 35. Lüscher TF, Yang Z, Tschudi M, von Segesser L, Stulz P, Boulanger C, et al. Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins. Circ Res. 1990;66(4):1088-94. DOI: https://doi.org/10.1161/01.res.66.4.1088 36. Barton M, Shaw S, d’Uscio LV, Moreau P, Lüscher TF. Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation. Biochem Biophys Res Commun. 1997;238(3):861-5. DOI: https://doi.org/10.1006/bbrc.1997.7394 37. Papafaklis MI, Koskinas KC, Chatzizisis YS, Stone PH, Feldman CL. In-vivo assessment of the natural history of coronary atherosclerosis: vascular remodeling and endothelial shear stress determine the complexity of atherosclerotic disease progression. Curr Opin Cardiol. 2010;25(6):627-38. DOI: https://doi.org/10.1097/hco.0b013e32833f0236 38. Chatzizisis YS, Giannoglou GD. Pulsatile flow: a critical modulator of the natural history of atherosclerosis. Med Hypotheses. 2006;67(2):338-40. DOI: https://doi.org/10.1016/j.mehy.2006.02.005 39. Lerman A, Zeiher AM. Endothelial function: cardiac events. Circulation. 2005;111(3):363-8. DOI: https://doi.org/10.1161/01.cir.0000153339.27064.14 40. Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res. 2000;87(10):840-4. DOI: https://doi.org/10.1161/01.res.87.10.840 41. Thorin E, Webb DJ. Endothelium-derived endothelin-1. Pflugers Arch. 2010;459(6):951-8. DOI: https://doi.org/10.1007/s00424-009-0763-y 42. Jaguszewski M, Osipova J, Ghadri JR, Nap L, Widera C, Franke J, et al. A signature of circulating microRNAs differentiates takotsubo cardiomyopathy from acute myocardial infarction. Eur Heart J. 2014;35(15):999-1006. DOI: https://doi.org/10.1093/eurheartj/eht392 43. Anderson TJ, Gerhard MD, Meredith IT, Charbonneau F, Delangrange D, Creager MA, et al. Systemic nature of endothelial dysfunction in atherosclerosis. Am J Cardiol. 1995;75(6):71b-4b. DOI: https://doi.org/10.1016/0002-9149(95)80017-m 44. Robertson D, Johnson GA, Robertson RM, Nies AS, Shand DG, Oates JA. Comparative assessment of stimuli that release neuronal and adrenomedullary catecholamines in man. Circulation. 1979;59(4):637-43. DOI: https://doi.org/10.1161/01.cir.59.4.637 45. Zeiher AM, Drexler H, Wollschlaeger H, Saurbier B, Just H. Coronary vasomotion in response to sympathetic stimulation in humans: importance of the functional integrity of the endothelium. J Am Coll Cardiol. 1989;14(5):1181-90. DOI: https://doi.org/10.1016/0735-1097(89)90414-2 46. Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: the Task Force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC). Eur Heart J. 2020;41(3):407-77. DOI: https://doi.org/10.1093/eurheartj/ehz425 47. Ford TJ, Ong P, Sechtem U, Beltrame J, Camici PG, Crea F, et al. Assessment of vascular dysfunction in patients without obstructive coronary artery disease: why, how, and when. JACC Cardiovasc Interv. 2020;13(16):1847-64. DOI: https://doi.org/10.1016/j.jcin.2020.05.052 48. Prinzmetal M, Kennamer R, Merliss R, Wada T, Bor N. Angina pectoris. I. A variant form of angina pectoris; preliminary report. Am J Med. 1959;27:375-88. DOI: https://doi.org/10.1016/0002-9343(59)90003-8; https://revibiomedica.sld.cu/index.php/ibi/article/view/2968

  5. 5
    Academic Journal
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    Academic Journal
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    Academic Journal
  8. 8
    Dissertation/ Thesis
  9. 9
    Dissertation/ Thesis
  10. 10
    Academic Journal
  11. 11
    Review
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    Academic Journal
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    Academic Journal
  14. 14
    Dissertation/ Thesis

    المؤلفون: Sans Roselló, Jordi

    المساهمون: Álvarez García, Jesús, Cinca, Juan

    المصدر: TDX (Tesis Doctorals en Xarxa)

    Time: 61

    وصف الملف: 173 p.; application/pdf

  15. 15
    Academic Journal
  16. 16
    Academic Journal

    المؤلفون: Vega Candelario, Rodolfo

    المساهمون: Hospital Provincial Docente Roberto Rodríguez Fernández -Morón - Ciego de Ávila -Cuba

    المصدر: Revista Cubana de Medicina Intensiva y Emergencias; Vol. 19, No. 3 (2020): julio-septiembre ; 1810-2352

    وصف الملف: application/pdf

    Relation: http://www.revmie.sld.cu/index.php/mie/article/view/689/pdf; Bitar P, Paolinelli P, Furnaro F. Tomografía Computada Cardíaca. Estado actual. Rev. Med. Clin. Condes. 2018 [citado: 23/02/2019];29(1):33-43. Disponible en: https://www.clinicalascondes.cl/Dev_CLC/media/Imagenes/PDF%20revista%20m%C3%A9dica/2013/1%20enero/7-Dra.Bitar.pdf; Helmy IM, Akram MA, Elfiki IM, Osama E, Arafa OE. A Pictorial Review on the Role of 64-Slice HD MDCT in Detecting Post CABG Cardiothoracic Complications. Open Journal of Thoracic Surgery. 2014 Jun [citado: 23/02/2019];4(2):48-58. Disponible en: https://www.scirp.org/pdf/OJTS_2014062610412908.pdf; Rochitte CE, George RT, Chen MY, Armin CA, Dewey M, Miller JM, et al. Age- and sex-related differences in all-cause mortality risk based on coronary computed tomography angiography findings results from the International Multicenter CONFIRM (Coronary CT Angiography Evaluation for Clinical Outcomes: An International Multicenter Registry) of 23,854 patients without known coronary artery disease. J Am Coll Cardiol. 2011 [citado: 23/02/2019];58:849-60. Disponible en: https://www.sciencedirect.com/science/article/pii/S0735109711019541?via%3Dihub; Rochitte CE, George RT, Chen MY, Arbab-Zadeh A, Dewey M, Miller JM, et al. Computed tomography angiography and perfusion to assess coronary artery stenosis causing perfusion defects by single photon emission computed tomography: the CORE320 study. Eur Heart J. 2014 [citado: 23/02/2019];35:1120-30. Disponible en: https://academic.oup.com/eurheartj/article/35/17/1120/2465942; Kimura Hayama ET, Alexánderson Rosas E, Vázquez-Lamadrid J, Pale R, Talayero Petra JA, Cruz Garciavilla P. Tomografía computada multidetector de arterias coronarias: estado del arte. Parte I: Aspectos técnicos. Arch Cardiol Méx. 2007 [citado: 22/10/2019];77(2). Disponible en: http://www.scielo.org.mx/pdf/acm/v77n2/v77n2a7.pdf; Yip A, Saw J. Spontaneous coronary artery dissection—A review. Cardiovasc Diagn Ther 2015;5(1):37-48. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329168/pdf/cdt-05-01-037.pdf; Bitar P. Evaluación cardiaca con tomografía computada y resonancia magnética. Rev Med Clínica las Condes. 2013 [citado: 22/10/2019];24(1):54-62. Disponible en: https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-evaluacion-cardiaca-con-tomografia-computada-S0716864013701299; Dahmani R, Ben Said R, Arous Y, Mahfoudhi H, Chourabi C, Ghommidh M, et al. Contribution of cardiac magnetic resonance imaging in the diagnosis of acute coronary syndrome with normal coronary angiography. Tunis Med. 2016 [citado: 26/02/2018];94(6):167-72. Disponible en: https://europepmc.org/article/med/28051221; Ahumada S, Restrepo G. Ecocardiografía en infarto agudo de miocardio. Rev. Colomb. Cardiol. 2014 [citado: 15/02/2019];21(3):164-73. Disponible en:http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0120-56332014000300008; Chacón-Hernández N, San Miguel-Cervera D, Vilar-Herrero V, Rumiz-González E, Berenguer-Jofresa A, Morell-Cabedo S. Síndrome coronario agudo en pacientes con arterias coronarias normales: estudio con tomografía de coherencia óptica. Rev Esp Cardiol. 2015 [citado: 15/02/2018];68(6):531-43. Disponible en: https://www.revespcardiol.org/es-pdf-S0300893215001153; Suzuki H. Different definition of microvascular angina. Eur J Clin Invest. 2015 [citado: 21/02/2018];45(12):1360-6. Disponible en: https://www. sciencedirect.com/science/article/pii/S1936879814005093?via%3Dihub; Bairey Merz CN, Pepine CJ, Walsh MN, Fleg JL. Ischemia and no obstructive coronary artery disease (INOCA): Developing Evidence-based Therapies and Research Agenda for the Next Decade. Circulation. 2017 March [citado: 15/01/2019];135(11):1075-92. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385930/pdf/nihms850333.pdf; Valle Alonso J, González Marante CA, Bandera S. Presentaciones electrocardiográficas atípicas en pacientes con síntomas isquémicos, tiempo de cambiar la estrategia. Revista Cubana de Cardiología y Cirugía Cardiovascular. 2017 [citado: 23/02/2019];23(2). Disponible en: https://www.medigraphic.com/pdfs/cubcar/ccc-2017/ccc173i.pdf; Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). European Heart Journal. 2018 [citado: 22/02/2019];39(2):119-77. Disponible en: https://academic.oup.com/eurheartj/article/39/2/119/4095042; Zuluaga-Quintero M, Cano-Granda CC. Infarto agudo de miocardio sin enfermedad coronaria ateroesclerótica obstructiva. Iatreia. 2018 Oct-Dic [citado: 15/01/2019];31(4):371-9. Disponible en: https//pdfs.semanticscholar.org/ec8e/7de78052caa0e30c86b8603656cfbb58ea36.pdf; Rodríguez Jiménez AE, Cruz Inerarity H, Valdés Arias B, Quintana Cañizares G, Toledo Rodríguez E. Duración del QRS como predictor de baja fracción de eyección en el infarto miocárdico con elevación del ST. CorSalud. 2018 Ene-Mar [citado: 15/05/2018];10(1):13-20. Disponible en: https://www.medigraphic.com/pdfs/ corsalud/cor-2018/cor181c.pdf; Pries AR, Badimon L, Bugiardini R, Camici PG, Dorobantu M, Duncker DJ, et al. Coronary vascular regulation, remodeling, and collateralization: mechanisms and clinical implications on behalf of the working group on coronary pathophysiology and microcirculation. Eur Heart J. 2015 [citado: 20/01/2018];36(45):3134-46. Disponible en: https:// academic.oup.com/eurheartj/article/36/45/3134/2293394; Vaccarino V, Badimon L, Corti R, de Wit C, Dorobantu M, Hall A, et al. Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology. Cardiovasc Res. 2011 [citado: 22/02/2018];90(1):9-12. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058737/pdf/cvq394.pdf; Vega Candelario R. Síndrome X de microcirculación coronaria, espasmo coronario e infarto agudo de miocardio en pacientes sin lesiones coronarias significativas. Rev. CorSalud. 2018 [citado: 23/02/2019];10(2):170-3. 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