المؤلفون: Greet Meurs, Vera Hillewaert, Ilse Weuts, Ben Van Hove, Scott Bone, Hector Novoa de Armas, Michiel Van Speybroeck, Geert Verreck, Katrien Backx, Loes Verheyen, Emma Kesselaers, Marieke Voets, Katrien Van Geel, David T. Vodak, Casey Jager, Petros A. Psathas, Jens Ceulemans, Monica Vialpando, Marcus E. Brewster, Sophie Lachau-Durand, Peter Boeykens, Stefanie Smulders, Claire Mackie

المصدر: Journal of Pharmaceutical Sciences

مصطلحات موضوعية: Male, SDD, spray-dried dispersion, amorphous, Pharmaceutical Science, FeSSIF, fed state simulated intestinal fluid, 02 engineering and technology, Flubendazole, Pharmaceutics, Drug Delivery and Pharmaceutical Technology, 030226 pharmacology & pharmacy, Rats, Sprague-Dawley, Papp, apparent permeability coefficient, AUC, area under the curve, chemistry.chemical_compound, Drug Delivery Systems, 0302 clinical medicine, oral absorption, RS, reference solution, Vitamin E, Cmax, maximum drug concentration, Tg, glass transition temperature, FA, formic acid, solid dispersion, Active ingredient, Tm, melting temperature, Chemistry, Antinematodal Agents, SSDD, standard spray-dried dispersion, Povidone, poorly water soluble drugs, 021001 nanoscience & nanotechnology, DCM, dichloromethane, Mebendazole, filarial disease, Drug delivery, OMS, ordered mesoporous silica, API, active pharmaceutical ingredient, 0210 nano-technology, NH4Ac, ammonium acetate, Research Article, HPMC, hydroxypropylmethylcellulose, Drug Compounding, MPSDD, modified process spray-dried dispersion, Cmax, formulation, Polyethylene glycol, Methylcellulose, PK, pharmacokinetic, 03 medical and health sciences, Suspensions, Pharmacokinetics, TPGS, tocopheryl polyethylene glycol succinate, Animals, spray drying, Desiccation, flubendazole, Chromatography, RH, relative humidity, Mouth Mucosa, HPMCAS, hydroxypropylmethylcellulose acetate succinate, Humidity, ACN, acetonitrile, Mesoporous silica, Rats, Bioavailability, PVP VA, polyvinylpyrrolidone-vinyl acetate, ordered mesoporous silica

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba002196fb7c6513354a1161e7e5496

المؤلفون: Laurent Schueller, Tinne Daems, Branko Bugarski, Filip Kiekens, Katarina Bukara, Cristian Libanati, Jan Rosier, Françoise Frérart, Michiel Van Speybroeck, Johan A. Martens, Koen Jolling, Siemon Eelen, Marjan De Gieter, Loes Verheyden, Guy Van den Mooter, Mark A. Martens

المصدر: European journal of pharmaceutics and biopharmaceutics
European Journal of Pharmaceutics and Biopharmaceutics

مصطلحات موضوعية: Adult, Male, Bioavailability, Silicon dioxide, Cmax, Pharmaceutical Science, Administration, Oral, Biological Availability, 02 engineering and technology, Absorption (skin), 030226 pharmacology & pharmacy, Absorption, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Fenofibrate, Limit of Detection, Ordered mesoporous silica, medicine, Humans, Solubility, Active metabolite, Chromatography, Cross-Over Studies, Chemistry, Pharmacology. Therapy, Water, General Medicine, Mesoporous silica, Middle Aged, 021001 nanoscience & nanotechnology, Silicon Dioxide, Healthy Volunteers, Area Under Curve, Female, 0210 nano-technology, Porosity, Biotechnology, medicine.drug

وصف الملف: Print-Electronic; application/msword; pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbf7e3e3a8c67d95c9c8c3c6731a6a2d
https://pubmed.ncbi.nlm.nih.gov/27648957

المؤلفون: Thao Do Thi, Patrick Augustijns, Guy Van den Mooter, Michiel Van Speybroeck, Randy Mellaerts, Jan Van Humbeeck, Pieter Annaert, Johan A. Martens

المصدر: Journal of Pharmaceutical Sciences. 100:4864-4876

مصطلحات موضوعية: Supersaturation, Chromatography, Calorimetry, Differential Scanning, Chemistry, Indomethacin, Biological Availability, Pharmaceutical Science, Hydrogen-Ion Concentration, Mesoporous silica, Silicon Dioxide, Solvent, Adsorption, Pharmaceutical Preparations, Solubility, Gastric Mucosa, Glyburide, Absorption (chemistry), Mesoporous material, Dissolution

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623a27b5c0ef232855b48cb1ddce9d96
https://doi.org/10.1002/jps.22703

المؤلفون: Michiel Van Speybroeck, Thao Do Thi, Jan Vermant, Patrick Augustijns, Jan Van Humbeeck, Luc Baudemprez, Guy Van den Mooter, Pieter Annaert, Johan A. Martens, Koen Nauwelaerts

المصدر: Journal of Inclusion Phenomena and Macrocyclic Chemistry. 71:137-147

مصطلحات موضوعية: chemistry.chemical_classification, Danazol, Aqueous solution, Cyclodextrin, General Chemistry, Condensed Matter Physics, Crystallography, chemistry, Stability constants of complexes, Phase (matter), medicine, Proton NMR, Solubility, Stoichiometry, Food Science, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::8b3d2fc15c47365d21567a7fae5102be
https://doi.org/10.1007/s10847-010-9917-y

المؤلفون: Koen Nauwelaerts, Patrick Augustijns, Thao Do Thi, Guy Van den Mooter, Jan Van Humbeeck, Matheus Froeyen, Luc Baudemprez, Michiel Van Speybroeck, Pieter Annaert, Johan A. Martens

المصدر: Journal of Pharmaceutical Sciences. 99:3863-3873

مصطلحات موضوعية: Models, Molecular, chemistry.chemical_classification, Magnetic Resonance Spectroscopy, Cyclodextrin, Stereochemistry, Chemical shift, beta-Cyclodextrins, Anti-Inflammatory Agents, Pharmaceutical Science, Ring (chemistry), Methylprednisolone, 2-Hydroxypropyl-beta-cyclodextrin, Inclusion compound, chemistry.chemical_compound, Crystallography, Solubility, chemistry, medicine, Outer sphere electron transfer, Proton NMR, gamma-Cyclodextrins, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5cf44dd27422c6302d0934ea956933
https://doi.org/10.1002/jps.22227

المؤلفون: Patrick Augustijns, Michiel Van Speybroeck, Rafaël Mols, Pieter Annaert, Johan A. Martens, Guy Van den Mooter, Thao Do Thi, Randy Mellaerts, Jan Van Humbeeck

المصدر: European Journal of Pharmaceutics and Biopharmaceutics. 75:354-365

مصطلحات موضوعية: Male, Antifungal Agents, Administration, Oral, Pharmaceutical Science, Mass Spectrometry, In vivo, Animals, Rats, Wistar, Supersaturation, Chromatography, Calorimetry, Differential Scanning, Chemistry, Precipitation (chemistry), General Medicine, Mesoporous silica, Silicon Dioxide, Rats, Bioavailability, Solubility, Adsorption, Itraconazole, Weak base, Mesoporous material, Chromatography, Liquid, Biotechnology, Mesoporous silicate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbe651d1d4658b943c65f62e69d1279
https://doi.org/10.1016/j.ejpb.2010.04.009

المؤلفون: Guy Van den Mooter, Michiel Van Speybroeck, Randy Mellaerts, Hong Chen, Patrick Augustijns, Johan A. Martens, Jan Van Humbeeck, Ken Elen, Kristof Houthoofd, Jules Mullens

المصدر: Microporous and Mesoporous Materials. 130:154-161

مصطلحات موضوعية: Chromatography, Chemistry, General Chemistry, Mesoporous silica, Condensed Matter Physics, law.invention, Thermogravimetry, Adsorption, Differential scanning calorimetry, Hydrophily, Chemical engineering, Mechanics of Materials, law, General Materials Science, Relative humidity, Crystallization, Mesoporous material

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c97e7594395edec9eb52a65698b10408
https://doi.org/10.1016/j.micromeso.2009.10.026

المؤلفون: Michiel Van Speybroeck, Bernard Van Eerdenbrugh, Johan A. Martens, Guy Van den Mooter, Ludo Froyen, Rafaël Mols, Jan Van Humbeeck, Kristof Houthoofd, Patrick Augustijns

المصدر: European Journal of Pharmaceutical Sciences. 38:270-278

مصطلحات موضوعية: Materials science, Chromatography, Itraconazole, Pharmaceutical Science, Amorphous solid, law.invention, Differential scanning calorimetry, law, medicine, Dissolution testing, Solubility, Crystallization, Dissolution, Powder diffraction, medicine.drug, Nuclear chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a89c69a18432ae27305135535d662e21
https://doi.org/10.1016/j.ejps.2009.08.002

المؤلفون: Michiel Van Speybroeck, Patrick Augustijns, Jan Vermant, Jan Van Humbeeck, Thao Do Thi, Randy Mellaerts, Valéry Barillaro, Guy Van den Mooter, Pieter Annaert, Johan A. Martens

المصدر: Journal of Pharmaceutical Sciences. 98:2648-2658

مصطلحات موضوعية: Chromatography, Chemistry, Chemistry, Pharmaceutical, Pharmaceutical Science, Excipient, Mesoporous silica, Silicon Dioxide, Differential scanning calorimetry, Pharmaceutical Preparations, Solubility, medicine, Dissolution testing, Mesoporous material, Porosity, Dissolution, Mesoporous silicate, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4492e377cf13867212f4721d9a89bd0d
https://doi.org/10.1002/jps.21638

المؤلفون: Paolo P. Pescarmona, Jan Van Humbeeck, Jan Vermant, Thao Do Thi, Patrick Augustijns, Johan A. Martens, Valéry Barillaro, Guy Van den Mooter, Michiel Van Speybroeck

المصدر: Journal of Combinatorial Chemistry. 10:637-643

مصطلحات موضوعية: Time Factors, Polymers, Chemistry, Pharmaceutical, Excipient, Excipients, Automation, Surface-Active Agents, medicine, Combinatorial Chemistry Techniques, Dissolution testing, Dissolution, Chromatography, High Pressure Liquid, chemistry.chemical_classification, Gastric Juice, Chromatography, Chemistry, General Chemistry, Polymer, Casting, Solvent, Solubility, Phenytoin, Solvents, Anticonvulsants, Absorption (chemistry), Dispersion (chemistry), medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1120bb03ca1201377de88dca971d5081
https://doi.org/10.1021/cc8000585

المؤلفون: Laurent Schueller, Yasmine Masmoudi, Abir Bouledjouidja, Michiel Van Speybroeck, Elisabeth Badens

المساهمون: Laboratoire de Mécanique, Modélisation et Procédés Propres (M2P2), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), MASMOUDI, Yasmine, Centre National de la Recherche Scientifique (CNRS)-École Centrale de Marseille (ECM)-Aix Marseille Université (AMU)

المصدر: International Journal of Pharmaceutics
International Journal of Pharmaceutics, 2016, 499, pp.1-9
International Journal of Pharmaceutics, Elsevier, 2016, 499, pp.1-9

مصطلحات موضوعية: Time Factors, Silicon dioxide, [SPI] Engineering Sciences [physics], Chemistry, Pharmaceutical, Pharmaceutical Science, Biological Availability, 02 engineering and technology, 030226 pharmacology & pharmacy, 03 medical and health sciences, Crystallinity, chemistry.chemical_compound, [SPI]Engineering Sciences [physics], 0302 clinical medicine, Fenofibrate, Solubility, Hypolipidemic Agents, Active ingredient, Chromatography, Supercritical carbon dioxide, Chemistry, Mesoporous silica, Carbon Dioxide, 021001 nanoscience & nanotechnology, Silicon Dioxide, Supercritical fluid, Bioavailability, Chemical engineering, 13. Climate action, Solvents, 0210 nano-technology, Crystallization, Porosity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::258dba30da5b0f189fb6e7c3c69f7be8
https://hal.science/hal-01266561

المؤلفون: Michiel Van Speybroeck, Hywel David Williams, Patrick Augustijns, Christopher J.H. Porter

المصدر: Journal of pharmaceutical sciences. 103(6)

مصطلحات موضوعية: Drug Carriers, Chromatography, Cinnarizine, Mefenamic acid, Magnesium, Silicates, Pharmaceutical Science, chemistry.chemical_element, Magnesium Compounds, Lipids, Dilution, Surface-Active Agents, Adsorption, chemistry, Pulmonary surfactant, Desorption, medicine, Mesoporous material, Aluminum Compounds, Chromatography, High Pressure Liquid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1b5e690315fa685ff20cf55d4df27b8
https://pubmed.ncbi.nlm.nih.gov/24740767

المؤلفون: Michiel Van Speybroeck, Mette Uhre Anby, Hywel David Williams, Christopher J.H. Porter, Tri-Hung Nguyen, Patrick Augustijns

المصدر: Molecular pharmaceutics. 9(9)

مصطلحات موضوعية: Male, Chemistry, Pharmaceutical, Pharmaceutical Science, Administration, Oral, Biological Availability, Magnesium Compounds, Excipients, Rats, Sprague-Dawley, Adsorption, Drug Delivery Systems, In vivo, Desorption, Drug Discovery, medicine, Animals, Magnesium, Particle Size, Aluminum Compounds, Danazol, Drug Carriers, Chromatography, Chemistry, Silicates, Aqueous two-phase system, Water, Lipids, Bioavailability, Rats, Solubility, Drug delivery, Molecular Medicine, Aluminum Silicates, Emulsions, Mesoporous material, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeeac2623f7899c4e977ec379ad4b8ea
https://pubmed.ncbi.nlm.nih.gov/22870936

المؤلفون: Raf Mols, Pieter Annaert, Johan A. Martens, Jan Vermant, Guy Van den Mooter, Patrick Augustijns, Michiel Van Speybroeck, Jan Van Humbeeck, Thao Thi Do

المصدر: International journal of pharmaceutics. 414(1-2)

مصطلحات موضوعية: Male, Drug Compounding, Pharmaceutical Science, Polysorbates, Pharmacology, Glycerides, Excretion, Excipients, Surface-Active Agents, Drug Delivery Systems, Fenofibrate, In vivo, medicine, Animals, Humans, Solubility, Rats, Wistar, Hypolipidemic Agents, Supersaturation, Chemistry, In vitro, Gastrointestinal Contents, Rats, Soybean Oil, Gastrointestinal Tract, Models, Animal, Liberation, Caprylates, Drug metabolism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f41f73c3496890d195962ecd57ffac0
https://pubmed.ncbi.nlm.nih.gov/21596119

المؤلفون: Guy Van den Mooter, Randy Mellaerts, Patrick Augustijns, Pieter Annaert, Johan A. Martens, Michiel Van Speybroeck

المصدر: Controlled Release in Oral Drug Delivery ISBN: 9781461410034

مصطلحات موضوعية: Supersaturation, Adsorption, Chemical engineering, Chemistry, Precipitation (chemistry), Specific surface area, Absorption (chemistry), Mesoporous silica, Mesoporous material, Fumed silica

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e70e3707d9e75c0fc821b7cc1d75b3dc
https://doi.org/10.1007/978-1-4614-1004-1_10

المؤلفون: Gert De Cremer, Guy Van den Mooter, Johan A. Martens, Randy Mellaerts, Maarten B. J. Roeffaers, Patrick Augustijns, Jasper Jammaer, Michiel Van Speybroeck, Kristof Houthoofd, Johan Hofkens

المصدر: Physical chemistry chemical physics : PCCP. 13(7)

مصطلحات موضوعية: Magnetic Resonance Spectroscopy, Silicon dioxide, Analytical chemistry, Nile red, General Physics and Astronomy, Water, Nuclear magnetic resonance spectroscopy, Mesoporous silica, Silicon Dioxide, Hydrophobe, chemistry.chemical_compound, Adsorption, chemistry, MCM-41, Chemical engineering, Desorption, Oxazines, Spectroscopy, Fourier Transform Infrared, Physical and Theoretical Chemistry, Itraconazole, Hydrophobic and Hydrophilic Interactions, Porosity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eedea341443f9c4138c9f7e587931c4
https://pubmed.ncbi.nlm.nih.gov/21152589

المؤلفون: Guy Van den Mooter, Raf Mols, Pieter Annaert, Johan A. Martens, Thao Do Thi, Michiel Van Speybroeck, Patrick Augustijns, Jan Van Humbeeck, Randy Mellaerts

المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 41(5)

مصطلحات موضوعية: Supersaturation, Fenofibrate, Chemistry, Silicon dioxide, Stereochemistry, Chemistry, Pharmaceutical, Pharmaceutical Science, Mesoporous silica, Molecular sieve, Silicon Dioxide, Bioavailability, Absorption, Rats, chemistry.chemical_compound, MCM-41, Chemical engineering, Pharmaceutical Preparations, Solubility, medicine, Animals, Rats, Wistar, Porosity, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f417ab900436428ca57f8bc308bd9d19
https://pubmed.ncbi.nlm.nih.gov/20850527

المؤلفون: Bernard, Van Eerdenbrugh, Michiel, Van Speybroeck, Raf, Mols, Kristof, Houthoofd, Johan A, Martens, Ludo, Froyen, Jan, Van Humbeeck, Patrick, Augustijns, Guy, Van den Mooter

المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 38(3)

مصطلحات موضوعية: Male, Drug Carriers, Chemistry, Pharmaceutical, Silicon Dioxide, Polyethylene Glycols, Rats, Drug Stability, X-Ray Diffraction, Animals, Vitamin E, Itraconazole, Powders, Rats, Wistar, Crystallization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::2c9bdf4ed10a4fb71d03575a04a89ddd
https://pubmed.ncbi.nlm.nih.gov/19686846

المؤلفون: Johan A. Martens, Hong Chen, Patrick Augustijns, Jan Van Humbeeck, Randy Mellaerts, Michiel Van Speybroeck, Guy Van den Mooter, Jasper Jammaer

المصدر: Langmuir : the ACS journal of surfaces and colloids. 24(16)

مصطلحات موضوعية: Aqueous solution, Calorimetry, Differential Scanning, Molecular Structure, Chemistry, Water, Ibuprofen, Surfaces and Interfaces, Mesoporous silica, Condensed Matter Physics, Silicon Dioxide, Solvent, Adsorption, Differential scanning calorimetry, Chemical engineering, Solubility, Electrochemistry, Organic chemistry, General Materials Science, Computer Simulation, Itraconazole, Mesoporous material, Porosity, Spectroscopy, Incipient wetness impregnation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c4e033b90a32086fb073d8679cbe8a
https://pubmed.ncbi.nlm.nih.gov/18630936

المؤلفون: Randy Mellaerts, Jasper A. G. Jammaer, Michiel Van Speybroeck, Hong Chen, Jan Van Humbeeck, Patrick Augustijns, Guy Van den Mooter, Johan A. Martens

المصدر: Langmuir; Jul2008, Vol. 24 Issue 16, p8651-8659, 9p