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المؤلفون: Michael Winzker, Alexandra Friese, Uwe Koch, Petra Janning, Slava Ziegler, Herbert Waldmann
المصدر: Angewandte Chemie. 132:5644-5650
مصطلحات موضوعية: General Medicine
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2
المؤلفون: Herbert Waldmann, Petra Janning, Slava Ziegler, Michael Winzker, Philipp Küchler, Gunther Zimmermann
المصدر: Bioorganic & Medicinal Chemistry. 26:1426-1434
مصطلحات موضوعية: 0301 basic medicine, Protein subunit, Clinical Biochemistry, Pharmaceutical Science, CDC42, GTPase, Biochemistry, Interactome, Protein–protein interaction, Structure-Activity Relationship, 03 medical and health sciences, Prenylation, Drug Discovery, Humans, Molecular Biology, Cells, Cultured, Cyclic Nucleotide Phosphodiesterases, Type 6, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Cell biology, 030104 developmental biology, Proteome, Molecular Medicine, Carrier Proteins, Lamin, Protein Binding
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3
المؤلفون: Slava Ziegler, Michael Winzker, Alexandra Friese, Herbert Waldmann, Petra Janning, Uwe Koch
المصدر: Angewandte Chemie (International Ed. in English)
مصطلحات موضوعية: Cell, Allosteric regulation, Gene Expression, GTPase, 010402 general chemistry, 01 natural sciences, Catalysis, Cell Line, lipids, proteomics, medicine, Humans, Targeted Protein Degradation, Enzyme Inhibitors, Sterol Regulatory Element Binding Proteins, biology, 010405 organic chemistry, Chemistry, Communication, Lipid metabolism, General Chemistry, Lipid Metabolism, Cyclic Nucleotide Phosphodiesterases, Type 2, Communications, 0104 chemical sciences, Cell biology, Sterol regulatory element-binding protein, medicine.anatomical_structure, Chaperone (protein), Molecular Probes, Proteolysis, biology.protein, proteolysis-targeting chimeras (PROTACs), Mevalonate pathway, PDEδ, metabolism, Function (biology)
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4
المؤلفون: Daniel Rauh, Yao-Wen Wu, Michael Winzker, Makoto Muroi, Luca Laraia, Marjorie A. Carnero Corrales, Nobumoto Watanabe, Lucas Robke, André Richters, Stefano Tomassi, Julian Engel, Hiroyuki Osada, Herbert Waldmann, Tobias Engbring, Georgios Konstantinidis
المساهمون: Robke, L, Laraia, L, Carnero Corrales, Ma, Konstantinidis, G, Muroi, M, Richters, A, Winzker, M, Engbring, T, Tomassi, S, Watanabe, N, Osada, H, Rauh, D, Waldmann, H, Wu, Yw, Engel, J.
المصدر: Angewandte Chemie International Edition
مصطلحات موضوعية: 0301 basic medicine, phenotypic identification, Regulator, Cellular homeostasis, BAG3, 01 natural sciences, Catalysis, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Drug Discovery, Autophagy, Humans, Protein Kinase Inhibitors, Sirolimus, Organisk kemi, 010405 organic chemistry, Kinase, Chemistry, Organic Chemistry, Autophagosomes, General Medicine, General Chemistry, Metabolism, Phenotype, Class III Phosphatidylinositol 3-Kinases, 3. Good health, 0104 chemical sciences, lipid kinase VPS34, Cytosol, 030104 developmental biology, HEK293 Cells, Pyrimidines, Biochemistry, MCF-7 Cells, Pyrazoles, 030217 neurology & neurosurgery, HeLa Cells
وصف الملف: application/pdf
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المؤلفون: Sabine Wohlgemuth, Stefano Maffini, Herbert Waldmann, Michael Saur, Shyamal Mosalaganti, Jenny Keller, Pascaline Rombaut, Tanja Bange, Franz Herzog, Anika Altenfeld, Franziska Müller, Michael Winzker, Annemarie Wehenkel, Andrea Musacchio, Stefan Raunser, Arsen Petrovic
المساهمون: Max Planck Institute of Molecular Physiology, Max-Planck-Gesellschaft, Ludwig-Maximilians-Universität München (LMU), Technische Universität Dortmund [Dortmund] (TU), Universität Duisburg-Essen [Essen], J. Keller acknowledges support by the European Molecular Biology Organization long-term fellowship ALTF 331-2010. A. Wehenkel acknowledges support by the European Molecular Biology Organization long-term fellowship ALTF 662-2008 and Marie Curie Intra-European Fellowship. A. Musacchio acknowledges funding by the European Research Council Advanced Grant RECEPIANCE (grant 669686) and the Deutsche Forschungsgemeinschaft Collaborative Research Centre (CRC) 1093. F. Herzog is supported by the European Research Council StG MolStruKT (grant 638218) and by the Deutsche Forschungsgemeinschaft (grant GRK1721). S. Raunser gratefully acknowledges the Max Planck Society and the European Council under the European Union’s Seventh Framework Programme (FP7/2007–2013, grant 615984)., We thank Marta Mattiuzzo and Anna De Antoni for sharing unpublished reagents, and we thank members of our laboratories for helpful discussions., European Project: 669686,H2020,ERC-2014-ADG,RECEPIANCE(2015), European Project: 638218,H2020,ERC-2014-STG,MolStruKT(2015), European Project: 615984,EC:FP7:ERC,ERC-2013-CoG,BACTERIAL SYRINGES(2014), Universität Duisburg-Essen = University of Duisburg-Essen [Essen]
المصدر: Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2017, 216 (4), pp.961-981. ⟨10.1083/jcb.201611060⟩
Journal of Cell Biology, 2017, 216 (4), pp.961-981. ⟨10.1083/jcb.201611060⟩
The Journal of Cell Biologyمصطلحات موضوعية: 0301 basic medicine, Cell Cycle Proteins, MESH: Spindle Apparatus / metabolism, Microtubules, MESH: Protein Transport / physiology, MESH: Dyneins / metabolism, MESH: Microtubules / metabolism, Kinetochores, Research Articles, RZZ complex, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], biology, Kinetochore, MESH: Kinetochores / metabolism, MESH: Cell Cycle Proteins / metabolism, Cell biology, Protein Transport, Spindle checkpoint, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM], MESH: M Phase Cell Cycle Checkpoints / physiology, Microtubule-Associated Proteins, MESH: Kinetochores / physiology, Biologie, endocrine system, MESH: Cell Line, Tumor, Dynein, Mitosis, Spindle Apparatus, MESH: Carrier Proteins / metabolism, Clathrin, Article, 03 medical and health sciences, MESH: Spindle Apparatus / physiology, Dynein ATPase, Cell Line, Tumor, Humans, MESH: Microtubule-Associated Proteins / metabolism, MESH: Humans, MESH: Mitosis / physiology, Dyneins, Cell Biology, Spindle apparatus, 030104 developmental biology, MESH: HeLa Cells, biology.protein, M Phase Cell Cycle Checkpoints, Carrier Proteins, HeLa Cells