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1Academic Journal
المؤلفون: Stephen Flowers, Brenda A. Petronella, Michael S. McQueney, Barbara Fanelli, Warren Eisenberg, Albert Uveges, Allison L. Roden, Scott Salowe, Venu Bommireddy, Jeffrey J. Letourneau, Chia-Yu Huang, James R. Beasley
المصدر: PLoS ONE, Vol 19, Iss 8 (2024)
وصف الملف: electronic resource
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المؤلفون: Henry M. Sarau, Feng Wang, Gerald E. Hunsberger, Elizabeth A. Capper-Spudich, Ralph A. Rivero, James J. Foley, Yonghui Wang, Zheng Yang, Laura S. Fisher, Todd L. Graybill, Michael S. McQueney, Jian Jin, Widdowson Katherine L, Zining Wu, Dulcie B. Schmidt, Terence J. Kiesow, Jakob Busch-Petersen
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:114-118
مصطلحات موضوعية: Receptors, CXCR3, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Piperazines, Structure-Activity Relationship, Camphor, chemistry.chemical_compound, stomatognathic system, immune system diseases, Drug Discovery, medicine, Humans, skin and connective tissue diseases, Molecular Biology, Sulfonamides, Organic Chemistry, Sulfonamide (medicine), hemic and immune systems, Combinatorial chemistry, stomatognathic diseases, chemistry, Molecular Medicine, medicine.drug
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المؤلفون: Michael S. McQueney, Roy A. Johanson, Elizabeth A. Capper-Spudich, Josephine H. Fox, Patricia L. Podolin, John J. Peterson, Robert W. Marquis, Edit Kurali, T. Gregg Davis, Dennis S. Yamashita, Stephen M. LoCastro, Gerald J. Terfloth, Brian R. Smith, Donald C. Carpenter, Edward Long, Xiaoyang Dong, Brian Bolognese
المصدر: The Journal of Immunology. 180:7989-8003
مصطلحات موضوعية: Male, Encephalomyelitis, Autoimmune, Experimental, Pyridines, Encephalomyelitis, T cell, Immunology, Cysteine Proteinase Inhibitors, Lymphocyte Activation, Mice, Antigen, Leucine, Cell Line, Tumor, MHC class I, medicine, Splenocyte, Animals, Humans, Immunology and Allergy, Collagen Type II, Cells, Cultured, Benzofurans, Mice, Knockout, biology, Chemistry, Experimental autoimmune encephalomyelitis, Histocompatibility Antigens Class II, Azepines, medicine.disease, Arthritis, Experimental, Cathepsins, Molecular biology, Raji cell, Antigens, Differentiation, B-Lymphocyte, Mice, Inbred C57BL, medicine.anatomical_structure, Mice, Inbred DBA, Cell culture, biology.protein, Cattle, Female, Protein Processing, Post-Translational, Spleen
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المؤلفون: Cynthia L. Burns-Kurtis, Josephine H. Fox, Saul Needle, Elizabeth A. Capper, Anne M. Romanic, Alan R. Olzinski, Michael S. McQueney, Fiona M. Kelly
المصدر: Cardiovascular Research. 62:610-620
مصطلحات موضوعية: Male, Neointima, Pathology, medicine.medical_specialty, Physiology, Blotting, Western, Hypercholesterolemia, Constriction, Pathologic, Biology, Polymerase Chain Reaction, Basement Membrane, Collagen Type I, Monocytes, Muscle, Smooth, Vascular, Extracellular matrix, Andrology, Cell Movement, Laminin, Physiology (medical), medicine, Animals, Humans, Cystatin C, Cathepsin S, Foam cell, Cathepsin, Extracellular Matrix Proteins, CATS, Macrophages, Cathepsins, Cystatins, Immunohistochemistry, Fibronectins, Femoral Artery, Lipoproteins, LDL, Fibronectin, biology.protein, Rabbits, Cardiology and Cardiovascular Medicine, Angioplasty, Balloon
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المؤلفون: Michael S. McQueney, Jianzhong Huang, Ricardo Macarron, Xinhe Jiang, Hu Li, Mark A. Seefeld
المصدر: SLAS Discovery. 8:712-715
مصطلحات موضوعية: Inorganic pyrophosphatase, Natural product, ATP synthase, biology, Isopentenyl pyrophosphate, Farnesyl pyrophosphate, Biochemistry, Pyrophosphate, Enzyme assay, Bacterial cell structure, Analytical Chemistry, chemistry.chemical_compound, chemistry, biology.protein, Molecular Medicine, Biotechnology
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المؤلفون: Maxine Gowen, Catherine J. Gress, Shing Mei Hwang, Michael W. Lark, Michael S. McQueney, Ian E. James, Robert W. Marquis, Simon M. Blake, Ru Yu, Daniel F. Veber, Hye-Ja Oh, Denise Zembryki, Thaddeus A. Tomaszek, Dennis S. Yamashita
المصدر: Journal of Biological Chemistry. 276:11507-11511
مصطلحات موضوعية: Cathepsin L, Osteoclasts, Cathepsin D, Cysteine Proteinase Inhibitors, Biochemistry, Bone resorption, Cathepsin O, Osteoclast, Endopeptidases, Tumor Cells, Cultured, medicine, Cathepsin K, Humans, Bone Resorption, Molecular Biology, Cathepsin, biology, Chemistry, Cell Biology, Cathepsins, Resorption, Cysteine Endopeptidases, medicine.anatomical_structure, biology.protein
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7
المؤلفون: Ward W. Smith, Thaddeus A. Tomaszek, Cheryl A. Janson, Baoguang Zhao, Mark Alan Levy, Dennis S. Yamashita, Sherin S. Abdel-Meguid, Ru Yu, Yen Jack Hwekwo, Daniel F. Veber, Scott K. Thompson, Thomas Joseph Carr, Robert W. Marquis, Karla J. D'Alessio, Carl F. Ijames, Michael S. McQueney, Hye-Ja Oh
المصدر: Bioorganic & Medicinal Chemistry. 7:581-588
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Cathepsin L, Cathepsin K, Clinical Biochemistry, Pharmaceutical Science, Cysteine Proteinase Inhibitors, Biochemistry, Cathepsin A, Cathepsin B, Cathepsin C, Cathepsin O, Cathepsin H, Cathepsin L1, Endopeptidases, Drug Discovery, Molecular Biology, Cathepsin S, Chemistry, Organic Chemistry, Ketones, Cathepsins, Cysteine Endopeptidases, Kinetics, Models, Chemical, Molecular Medicine
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المؤلفون: Karen M. Anderson, Michael S. McQueney, Sabine Rouanet, Marie Chabot-fletcher, Isabelle Berrebi-Bertrand, Robert B. Kirkpatrick, David C. Underwood
المصدر: Journal of Molecular and Cellular Cardiology. 31:705-719
مصطلحات موضوعية: Male, DNA, Complementary, Molecular Sequence Data, Gene Expression, Cardiomegaly, Biology, Muscle hypertrophy, Mice, Myotrophin, Right ventricular hypertrophy, Ventricular hypertrophy, Sequence Homology, Nucleic Acid, Complementary DNA, Gene expression, medicine, Animals, Humans, Tissue Distribution, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, Rats, Wistar, Growth Substances, education, Molecular Biology, Peptide sequence, Cells, Cultured, Cell Size, DNA Primers, Messenger RNA, education.field_of_study, Base Sequence, Hypertrophy, Right Ventricular, Sequence Homology, Amino Acid, Myocardium, medicine.disease, Molecular biology, Recombinant Proteins, Rats, Disease Models, Animal, Intercellular Signaling Peptides and Proteins, Cardiology and Cardiovascular Medicine
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المؤلفون: Kimberly A. Brun, Karla J. D'Alessio, Michael S. McQueney, Michael J. Orsini, Christine Debouck
المصدر: Protein Expression and Purification. 15:213-220
مصطلحات موضوعية: Sequence analysis, Recombinant Fusion Proteins, medicine.medical_treatment, Cathepsin K, Molecular Sequence Data, Osteoclasts, Biology, medicine.disease_cause, law.invention, Enzyme activator, Coumarins, law, Escherichia coli, medicine, Humans, Amino Acid Sequence, Protein Precursors, Peptide sequence, Fluorescent Dyes, Inclusion Bodies, chemistry.chemical_classification, Protease, Dipeptides, Cathepsins, Molecular biology, Enzyme Activation, Enzyme, Biochemistry, chemistry, Recombinant DNA, Biotechnology
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المؤلفون: Bernard Y. Amegadzie, Christopher Jones, Kannan Ramachandran, Michael S. McQueney, Fred H. Drake, Charles R. Hanning, Janice R. Connor, John A. Feild, Kimberly A. Brun
المصدر: Protein Expression and Purification. 14:387-394
مصطلحات موضوعية: Recombinant Fusion Proteins, Cathepsin K, Genetic Vectors, Molecular Sequence Data, Cathepsin E, Cathepsin F, Protein Sorting Signals, Spodoptera, Biology, Cathepsin A, Species Specificity, Cathepsin O, Cathepsin H, Animals, Humans, Amino Acid Sequence, Cloning, Molecular, Enzyme Inhibitors, Protein Precursors, Peptide sequence, Cathepsin, Base Sequence, Sequence Homology, Amino Acid, Cathepsins, Molecular biology, Nucleopolyhedroviruses, Enzyme Activation, Macaca fascicularis, Biochemistry, Female, Bone Remodeling, Sequence Alignment, Biotechnology
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المؤلفون: Brian Hellmig, Susan S. Hoog, Daniel J. O'Shannessy, Kevin O'Donnell, Cheryl A. Janson, Christine Debouck, Ward W. Smith, Michael S. McQueney, Anthony G. DiLella, Xiayang Qiu, Sherin S. Abdel-Meguid
المصدر: Biochemistry. 36:14023-14029
مصطلحات موضوعية: Models, Molecular, Proteases, Protein Conformation, Herpesvirus 2, Human, viruses, medicine.medical_treatment, Molecular Sequence Data, Herpesvirus 1, Human, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, Viral Proteins, Capsid, Organophosphorus Compounds, medicine, Protease Inhibitors, Serine protease, Binding Sites, Protease, biology, Protease inhibitor complex, Chemistry, Serine Endopeptidases, Subtilisin, medicine.disease, Virology, Recombinant Proteins, NS2-3 protease, Cold sore, Herpes simplex virus, biology.protein
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المؤلفون: Debra Dunaway-Mariano, William H. Swartz, Herman L. Ammon, Sheng Lian Lee, Patrick S. Mariano, Michael S. McQueney
المصدر: The Journal of Organic Chemistry. 56:7121-7130
مصطلحات موضوعية: Nucleophilic addition, Intramolecular reaction, Chemistry, Stereochemistry, Phosphorus, Intramolecular force, Organic Chemistry, chemistry.chemical_element, Stepwise reaction, Nuclear magnetic resonance spectroscopy, Carbon, Catalysis
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المؤلفون: Michael S. McQueney, Thomas D. Meek, James P. Villa, Patrick McDevitt, Jessica L. Schneck, Sara H. Thrall
المصدر: Biochemistry. 47(33)
مصطلحات موضوعية: Binding Sites, Chemistry, Stereochemistry, Protein Conformation, Kinetics, Water, Hydrogen-Ion Concentration, Deuterium, Biochemistry, Cathepsin C, Acylation, Burst kinetics, Reaction rate constant, Tetrahedral carbonyl addition compound, Kinetic isotope effect, Solvents, Humans, Sodium Hydroxide, Steady state (chemistry), Cloning, Molecular
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المؤلفون: Michael W. Lark, Ted Tomaszek, Kevin L. Salyers, David G. Tew, Chao-Pin Lee, Michael S. McQueney, George B. Stroup, Ian E. James, Antonia Marzulli, Hye-Ja Oh, Mark Alan Levy, Dennis S. Yamashita, Maxine Gowen, Brian R. Smith, Daniel F. Veber, Phil Smith
المصدر: Peptides for the New Millennium ISBN: 0792364457
مصطلحات موضوعية: medicine.anatomical_structure, Cathepsin O, Osteoclast, Preclinical pharmacokinetics, medicine, Cathepsin K, Theology, Cysteine protease, SmithKline Beecham, Active site cysteine
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المؤلفون: Jae U. Jeong, Keith W. Ward, Enoch Gao, Dennis S. Yamashita, Bing Wang, § H-Y. Cheng, Baoguang Zhao, Martha S. Head, Amy A. Sarjeant, § Louise M. Liable-Sands, Ian E. James, Neysa Nevins, Ren Xie, and Michael W. Lark, Karl F. Erhard, Denise Zembryki, Daniel F. Veber, Theresa J. Roethke, Robert W. Marquis, Brian R. Smith, Xiaoliu Geng, Michael S. McQueney, R. Curtis Haltiwanger, Ward W. Smith, Sirishkumar D. Nidamarthy, Catherine J. Gress, Priscilla H. Offen, Hye-Ja Oh, Cheryl A. Janson, Thaddeus A. Tomaszek, Fan Lin
المصدر: Journal of medicinal chemistry. 49(5)
مصطلحات موضوعية: Cell Membrane Permeability, Stereochemistry, medicine.drug_class, Cathepsin K, Molecular Conformation, Biological Availability, Carboxamide, Crystallography, X-Ray, Chemical synthesis, Cell Line, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Animals, Humans, Sulfones, chemistry.chemical_classification, biology, Bone Density Conservation Agents, Stereoisomerism, Azepines, Blood Proteins, Haplorhini, Cathepsins, In vitro, Bioavailability, Rats, Enzyme, chemistry, Biochemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Protein Binding
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المؤلفون: Patricia A. Elkins, Michael S. McQueney, Yen Sen Ho, Ward W. Smith, Maxwell D. Cummings, Karla J. D'Alessio, Cheryl A. Janson, Anne M. Romanic
المصدر: Acta crystallographica. Section D, Biological crystallography. 58(Pt 7)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Peptide, MMP9, Matrix metalloproteinase, Arginine, Crystallography, X-Ray, Protein Structure, Secondary, Structural Biology, Catalytic Domain, Hydrolase, Side chain, Escherichia coli, Humans, Collagenases, Cloning, Molecular, Protein secondary structure, chemistry.chemical_classification, Enzyme Precursors, Binding Sites, biology, General Medicine, Protein Structure, Tertiary, body regions, Fibronectin, Crystallography, chemistry, Matrix Metalloproteinase 9, Domain (ring theory), biology.protein, Gelatin, Electrophoresis, Polyacrylamide Gel, Peptides, Protein Binding
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المصدر: Analytical chemistry. 73(23)
مصطلحات موضوعية: Chromatography, Autoanalysis, Chemistry, Interface (computing), Automated data processing, Analytical chemistry, Mass spectrometry, High-performance liquid chromatography, Mass Spectrometry, Recombinant Proteins, Analytical Chemistry, High throughput analysis, Liquid chromatography–mass spectrometry, Indicators and Reagents, Spectrophotometry, Ultraviolet, Throughput (business), Communication channel, Chromatography, Liquid
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المؤلفون: M.W. Lark, Chao-Pin Lee, L.D Davis, M. E. Hemling, Ian E. James, G Trescher, Antonia Marzulli, Dennis S. Yamashita, B.R. Bradley, Thaddeus A. Tomaszek, H.-J. Oh, Kevin L. Salyers, B. Wang, R. C. Haltiwanger, Mark A. Levy, Cheryl A. Janson, R.A. Dodds, F Lin, H.-Y. Cheng, M. Gowen, Jin Zeng, S M Hwang, Catherine J. Gress, David G. Tew, Stephen M. LoCastro, J. W. Proksch, Beverley Smith, Ward W. Smith, Chad Quinn, Robert W. Marquis, Karl F. Erhard, Karla J. D'Alessio, Baoguang Zhao, Simon M. Blake, Michael S. McQueney, Cummings Maxwell D, Daniel F. Veber, Keith W. Ward, Ru Yu
المصدر: Journal of medicinal chemistry. 44(9)
مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, Cathepsin K, Administration, Oral, Biological Availability, Osteoclasts, In Vitro Techniques, Crystallography, X-Ray, Chemical synthesis, Mass Spectrometry, Structure-Activity Relationship, Leucine, Drug Discovery, Hydrolase, Animals, Humans, Enzyme Inhibitors, Chromatography, High Pressure Liquid, Cathepsin, biology, Molecular Structure, Chemistry, Active site, Stereoisomerism, Azepines, Cysteine protease, Cathepsins, Rats, Enzyme inhibitor, biology.protein, Molecular Medicine, Protein Binding
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المؤلفون: Andrew D. Gribble, Daniel F. Veber, Thaddeus A. Tomaszek, Stephen M. LoCastro, Robert W. Marquis, Michael S. McQueney, Chad Quinn, Cheryl A. Janson, Robert E. Lee Trout, Baoguang Zhao, Jin Zeng, Ward W. Smith, Ru Yu, Karla J. D'Alessio, David G. Tew, Jason Witherington, Benedicte Garnier, Mark E. Hemling, Ashley E. Fenwick
المصدر: Journal of medicinal chemistry. 44(5)
مصطلحات موضوعية: Models, Molecular, Ketone, Stereochemistry, Cathepsin K, Crystallography, X-Ray, Mass Spectrometry, chemistry.chemical_compound, Structure-Activity Relationship, Piperidines, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Furans, Pyrans, chemistry.chemical_classification, Binding Sites, biology, Molecular Structure, Diastereomer, Active site, Stereoisomerism, Ketones, Cysteine protease, Cathepsins, Pyrrolidinones, Rats, Papain, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Chromatography, Liquid
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المصدر: Biochemistry. 39(15)
مصطلحات موضوعية: S-Adenosylmethionine, Stereochemistry, Kinetics, Oxygen Isotopes, Ligands, Biochemistry, Pyrophosphate, Catalysis, Fluorescence, Phosphates, Hydrolysis, chemistry.chemical_compound, Reaction rate constant, Adenosine Triphosphate, Methionine, Biosynthesis, Isomerism, Polyphosphates, Escherichia coli, Computer Simulation, Amino Acid Sequence, Binding Sites, Titrimetry, Substrate (chemistry), Water, Methionine Adenosyltransferase, Phosphate, Diphosphates, Oxygen, chemistry, Solvents, Thermodynamics
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