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1Academic Journal
المؤلفون: Phillip C C Liu, Holly Koblish, Liangxing Wu, Kevin Bowman, Sharon Diamond, Darlise DiMatteo, Yue Zhang, Michael Hansbury, Mark Rupar, Xiaoming Wen, Paul Collier, Patricia Feldman, Ronald Klabe, Krista A Burke, Maxim Soloviev, Christine Gardiner, Xin He, Alla Volgina, Maryanne Covington, Bruce Ruggeri, Richard Wynn, Timothy C Burn, Peggy Scherle, Swamy Yeleswaram, Wenqing Yao, Reid Huber, Gregory Hollis
المصدر: PLoS ONE, Vol 15, Iss 4, p e0231877 (2020)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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2
المؤلفون: Qian Wang, Sybil O'Connor, Alan Roberts, Brian W. Metcalf, Leslie Hall, Maxim Soloviev, Michael Hansbury, Greg Hollis, Xin He, Matthew C. Stubbs, Niu Shin, Wenqing Yao, Kamna Katiyar, Phillip C.C. Liu, Kathy Wang, Sharon Diamond, Brent Douty, Gengjie Yang, Dana Shuey, Maryanne B. Covington, Paul Collier, Mingming Gao, Patricia Feldman, Peggy Scherle, Timothy Burn, Andrew P. Combs, Yun-Long Li, Lynn Leffet, Robert C. Newton, Paul Waeltz, Holly Koblish, Jin Lu, Swamy Yeleswaram, Yanlong Li, Reid Huber, Robert Collins, Eddy W. Yue
المصدر: Journal of Pharmacology and Experimental Therapeutics. 374:211-222
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Phosphoinositide 3-kinase, biology, Cell growth, business.industry, medicine.disease, In vitro, Lymphoma, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Mechanism of action, In vivo, Cell culture, biology.protein, Cancer research, Molecular Medicine, Medicine, medicine.symptom, business, 030217 neurology & neurosurgery, PI3K/AKT/mTOR pathway
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3
المؤلفون: Diana A. Arias, Stephen Douglass, Lisa Truong, Qian Wang, Kathy H. Wang, Gengjie Yang, Michael Hansbury, Sybil O’Connor, Kevin Bowman, Robert Collins, Matthew Stubbs, Leslie Hall, Christina Stevens, Christopher Maddage, Brent Douty, Maryanne Covington, Lynn Leffet, Eddy Yue, Andrew Combs, Sunkyu Kim, Niu Shin, Holly Koblish, Rodrigo Hess
المصدر: Cancer Research. 83:5162-5162
مصطلحات موضوعية: Cancer Research, Oncology
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4
المؤلفون: Brian M. Glass, Padmaja Polam, Tom Emm, Kevin Bowman, Jordan S. Fridman, Holly Koblish, Richard Wynn, Michael Hansbury, Yanlong Li, Eddy W. Yue, Brian Metcalf, Michael J. Bower, Min Wei, Richard B. Sparks, Peggy Scherle, Xiangdong Liu, Andrew P. Combs, Timothy Burn, Dilip P. Modi, Brian Wayland, Qian Wang, Lynn Leffet, Brent Douty, Wenyu Zhu, Amy Takvorian, Joseph Glenn
المصدر: ACS Medicinal Chemistry Letters
مصطلحات موضوعية: 0301 basic medicine, Letter, Organic Chemistry, data-centric medicinal chemistry, Pembrolizumab, Pharmacology, Furazan, Biochemistry, Small molecule, In vitro, Bioavailability, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, IDO1, chemistry, INCB24360, 030220 oncology & carcinogenesis, Drug Discovery, Epacadostat, Indoleamine 2,3-dioxygenase, immuno-oncology, Sulfamide, ADME
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5
المؤلفون: Niu, Shin, Matthew, Stubbs, Holly, Koblish, Eddy W, Yue, Maxim, Soloviev, Brent, Douty, Kathy He, Wang, Qian, Wang, Mingming, Gao, Patricia, Feldman, Gengjie, Yang, Leslie, Hall, Michael, Hansbury, Sybil, O'Connor, Lynn, Leffet, Robert, Collins, Kamna, Katiyar, Xin, He, Paul, Waeltz, Paul, Collier, Jin, Lu, Yun-Long, Li, Yanlong, Li, Phillip C C, Liu, Timothy, Burn, Maryanne, Covington, Sharon, Diamond, Dana, Shuey, Alan, Roberts, Swamy, Yeleswaram, Greg, Hollis, Brian, Metcalf, Wenqing, Yao, Reid, Huber, Andrew, Combs, Robert, Newton, Peggy, Scherle
المصدر: The Journal of pharmacology and experimental therapeutics. 374(1)
مصطلحات موضوعية: Pyrrolidines, Lymphoma, Antineoplastic Agents, Xenograft Model Antitumor Assays, Disease Models, Animal, Mice, Phosphatidylinositol 3-Kinases, Pyrimidines, Liver, Cell Line, Tumor, Animals, Humans, Immunologic Factors, Pyrazoles, Female, Phosphoinositide-3 Kinase Inhibitors
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6
المؤلفون: Peggy Scherle, Timothy Burn, Sharon Diamond, Ronald M. Klabe, Wenqing Yao, Liangxing Wu, Reid Huber, Darlise DiMatteo, Alla Volgina, Kevin Bowman, Holly Koblish, Bruce Ruggeri, Xin He, Krista A. Burke, Yue Zhang, Swamy Yeleswaram, Christine Gardiner, Richard Wynn, Maxim Soloviev, Maryanne B. Covington, Gregory Hollis, Mark Rupar, Xiaoming Wen, Patricia Feldman, Michael Hansbury, Phillip C.C. Liu, Paul Collier
المصدر: PLoS ONE, Vol 15, Iss 4, p e0231877 (2020)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, Fibroblast Growth Factor, Physiology, Kinase Inhibitors, Cancer Treatment, Administration, Oral, Mice, SCID, Fibroblast growth factor, Biochemistry, Cell Fusion, Cholangiocarcinoma, Mice, Endocrinology, 0302 clinical medicine, Neoplasms, Adenocarcinomas, Medicine and Health Sciences, Enzyme Inhibitors, Receptor, Multidisciplinary, Chemistry, Kinase, Body Fluids, Bioassays and Physiological Analysis, Blood, Oncology, Fibroblast growth factor receptor, 030220 oncology & carcinogenesis, Medicine, Female, Anatomy, Half-Life, Research Article, Cell Physiology, Morpholines, Science, Mice, Nude, Research and Analysis Methods, Carcinomas, Blood Plasma, Rats, Nude, 03 medical and health sciences, In vivo, Cell Line, Tumor, Growth Factors, Gastrointestinal Tumors, Animals, Humans, Receptor, Fibroblast Growth Factor, Type 3, Pyrroles, Pharmacokinetics, Receptor, Fibroblast Growth Factor, Type 1, Receptor, Fibroblast Growth Factor, Type 2, Protein Kinase Inhibitors, Enzyme Assays, Pharmacology, Endocrine Physiology, Fibroblast growth factor receptor 1, Biology and Life Sciences, Cancers and Neoplasms, Cell Biology, Fibroblast growth factor receptor 4, Xenograft Model Antitumor Assays, Rats, Mice, Inbred C57BL, Pyrimidines, 030104 developmental biology, Cell culture, Enzymology, Cancer research, Biochemical Analysis
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7
المؤلفون: Kristine Stump, Gengjie Yang, Luping Lin, Pramod Thekkat, Mingming Gao, Hui Wang, Swamy Yeleswaram, Susan Wee, Yingnan Chen, Jennifer Harris, Xiaozhao Wang, Sunkyu Kim, Chao Qi, Christina Stevens, Xiaodi Ren, Holly Koblish, Jennifer Mason, Maryanne Covington, Christopher Maddage, Kerri Kurzeja-Lipinski, Wenqing Yao, Michael Hansbury, Patricia Conlen, Alexandra Alexandra, Patricia Feldman
المصدر: Cancer Research. 81:LB157-LB157
مصطلحات موضوعية: Cancer Research, Tumor microenvironment, Chemistry, medicine.medical_treatment, T cell, Immunotherapy, Adenosine receptor antagonist, Adenosine, Adenosine receptor, medicine.anatomical_structure, Oncology, Cancer immunotherapy, medicine, Cancer research, Receptor, medicine.drug
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8
المؤلفون: Sharon Diamond, Gregory Hollis, Yue Zhang, Reid Huber, Christina Stevens, Liangxing Wu, Sybil O'Connor, Ashwini Kulkarni, Krista Burke, Peggy Scherle, Kaijiong Xiao, Jingwei Li, Karen Gallagher, Maryanne Covington, Yan-ou Yang, Michael Hansbury, Wenqing Yao, Gengjie Yang, Jonathan Rios-Doria, Holly Koblish, Liang-Chuan S. Wang
المصدر: Cancer Research. 79:4480-4480
مصطلحات موضوعية: Cancer Research, Effector, medicine.drug_class, Chemistry, media_common.quotation_subject, Immunogenicity, T cell, Monoclonal antibody, Small molecule, In vitro, Blockade, medicine.anatomical_structure, Oncology, medicine, Cancer research, Internalization, media_common
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9
المؤلفون: Qian Wang, Holly Koblish, Andrew P. Combs, Richard Wynn, Lynn Leffet, Robert C. Newton, Padmaja Polam, Kevin Bowman, Xiangdong Liu, Eddy W. Yue, Richard B. Sparks, Paul Waeltz, Peggy Scherle, Timothy Burn, Niu Shin, Gengjie Yang, Mark Rupar, Michael Hansbury, Jordan S. Fridman, Beth Thomas, Yanlong Li, Kathy Wang
المصدر: Blood. 115:3520-3530
مصطلحات موضوعية: Cellular immunity, T-Lymphocytes, medicine.medical_treatment, Immunology, Mice, Nude, Apoptosis, Biology, Biochemistry, Mice, chemistry.chemical_compound, Immune system, Neoplasms, medicine, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Enzyme Inhibitors, CD86, Immunity, Cellular, Mice, Inbred BALB C, Dose-Response Relationship, Drug, Cell growth, Dendritic Cells, Cell Biology, Hematology, Coculture Techniques, Tryptophan Oxygenase, In vitro, Cytokine, chemistry, Cancer research, B7-2 Antigen, Kynurenine, HeLa Cells
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10
المؤلفون: Jordan S. Fridman, Michael Hansbury, Richard B. Sparks, Andrew P. Combs, Gengjie Yang, Kevin Bowman, Holly Koblish, Paul Waeltz, Patrick J. Haley, Peggy Scherle, Timothy Burn, Kris Vaddi, Eddy W. Yue, Claire L. Neilan
المصدر: Molecular Cancer Therapeutics. 9:489-498
مصطلحات موضوعية: Cancer Research, Amidines, Pharmacology, Biology, Mice, chemistry.chemical_compound, Dogs, Immune system, In vivo, Cell Line, Tumor, Neoplasms, medicine, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Lymphocytes, Enzyme Inhibitors, Indoleamine 2,3-dioxygenase, Kynurenine, Mice, Inbred BALB C, Catabolism, Tryptophan, Cancer, medicine.disease, In vitro, Oncology, chemistry, Immune System, Female, Immunotherapy, Lymph Nodes, Lymph
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11
المؤلفون: Jim Winkler, Jerry L. Adams, Yanhong Feng, Johnson Neil W, Michael Hansbury, Marcus Semones
المصدر: Bioorganic & Medicinal Chemistry Letters. 17:4756-4760
مصطلحات موضوعية: Models, Molecular, Pyridines, Angiogenesis, p38 mitogen-activated protein kinases, Clinical Biochemistry, Pharmaceutical Science, p38 Mitogen-Activated Protein Kinases, Biochemistry, Inhibitory Concentration 50, Mice, Growth factor receptor, immune system diseases, In vivo, Cell Line, Tumor, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Molecular Biology, biology, Chemistry, Kinase, Organic Chemistry, Imidazoles, Receptor, TIE-2, Angiopoietin receptor, Models, Chemical, Enzyme inhibitor, Drug Design, biology.protein, Cancer research, Molecular Medicine, Signal transduction, Neoplasm Transplantation, Plasmacytoma
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12
المؤلفون: Kris Vaddi, Jordan S. Fridman, Jincong Zhuo, Qian Wang, Genjie Yang, Sufi M. Thomas, Bin-Bing S. Zhou, Maxwell Pan, Wenqing Yao, Steven Friedman, Xiangdong Liu, Robert C. Newton, Eian Caulder, Peggy Scherle, Michael Hansbury, Yvonne Lo, Jennifer R. Grandis
المصدر: Clinical Cancer Research. 13:1892-1902
مصطلحات موضوعية: Cancer Research, Proteases, Mice, Nude, CHO Cells, Biology, Matrix metalloproteinase, Models, Biological, Mice, Cricetulus, ErbB, Cricetinae, Neoplasms, medicine, Animals, Humans, Protein kinase B, Cells, Cultured, Mice, Inbred BALB C, Metalloproteinase, Cancer, Oncogene Proteins v-erbB, medicine.disease, Xenograft Model Antitumor Assays, Rats, ADAM Proteins, Oncology, Biochemistry, Ectodomain, Cancer research, Phosphorylation, Signal Transduction
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13
المؤلفون: Paul Waeltz, Liang-Chuan S. Wang, Gregory Hollis, Yue Zhang, Eddy W. Yue, Nikoo Falahatpisheh, Reid Huber, Peggy Scherle, Timothy Burn, Thomas Maduskuie, Brent Douty, Yun-Long Li, Gengjie Yang, Andrew P. Combs, Holly Koblish, Mark Rupar, Michael Hansbury
المصدر: Journal for Immunotherapy of Cancer
مصطلحات موضوعية: Pharmacology, Cancer Research, Tumor microenvironment, T cell, medicine.medical_treatment, Immunology, FOXP3, Immunotherapy, Biology, Immune system, medicine.anatomical_structure, Oncology, Poster Presentation, medicine, Molecular Medicine, Immunology and Allergy, Cytotoxic T cell, IL-2 receptor, CD8
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14
المؤلفون: Sharon Diamond-Fosbenner, Maryanne B. Covington, Gregory Hollis, Wenqing Yao, Liangxing Wu, Peggy Scherle, Timothy Burn, Sindy Condon, Karen Gallagher, Darlise DiMatteo, Xiaoming Wen, Yan-ou Yang, Michael Hansbury, Richard Wynn, Liang Lu, Phillip C.C. Liu, Swamy Yeleswaram, Ding-Quan Qian, Xin He, Bruce Ruggeri, Matthew C. Stubbs, Ronald M. Klabe, Reid Huber, Kevin Bowman, Paul Collier
المصدر: Cancer Research. 77:2100-2100
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Kinase, Chemistry, Autophosphorylation, Fibroblast growth factor, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Oncology, Fibroblast growth factor receptor, Cancer research, Signal transduction, Growth inhibition, Autocrine signalling, Receptor
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15
المؤلفون: Yue Zhang, Thomas F. Gajewski, Sybil O'Connor, Christina Stevens, Kerri Lasky, Thomas Condamine, Reid Huber, Leslie Hall, Liang-Chuan Wang, Peggy A. Scherle, Gregory F. Hollis, Michael Hansbury, Horacio Nastri, Brendan Horton, Holly Koblish
المصدر: Cancer Research. 77:2618-2618
مصطلحات موضوعية: Agonist, Cancer Research, Oncology, biology, business.industry, medicine.drug_class, biology.protein, Medicine, Epacadostat, Pharmacology, Antibody, business
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16
المؤلفون: Holly K. Koblish, Michael Hansbury, Leslie Hall, Liang-Chuan Wang, Yue Zhang, Maryanne Covington, Timothy Burn, Mark Rupar, Christine Gardiner, Thomas Condamine, Kerri Lasky, Matthew C. Stubbs, Eddy Yue, Richard Sparks, Thomas Maduskuie, Andrew P. Combs, Gregory Hollis, Reid Huber, Phillip CC Liu, Peggy Scherle
المصدر: Cancer Research. 76:4904-4904
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Tumor microenvironment, medicine.medical_treatment, T cell, Cancer, Immunotherapy, Biology, medicine.disease, BET inhibitor, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Immune system, medicine.anatomical_structure, Oncology, In vivo, 030220 oncology & carcinogenesis, Immunology, medicine, Cancer research, BET Inhibitor INCB054329
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17
المؤلفون: Xiangdong Liu, Andrew P. Combs, Min Wei, Changnian Liu, Peggy Scherle, Kevin Bowman, Timothy Burn, Jordan S. Fridman, Yanlong Li, Brian Wayland, Richard Wynn, Brent Douty, Holly Koblish, Brian Metcalf, Michael J. Bower, Lynn Leffet, Michael Hansbury, Qian Wang, Eddy W. Yue
المصدر: Journal of medicinal chemistry. 52(23)
مصطلحات موضوعية: Models, Molecular, Amidines, Molecular Conformation, Pharmacology, Binding, Competitive, HeLa, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Non-competitive inhibition, In vivo, Drug Discovery, Animals, Humans, Indoleamine-Pyrrole 2,3,-Dioxygenase, Enzyme Inhibitors, Indoleamine 2,3-dioxygenase, IC50, Melanoma, biology, Chemistry, biology.organism_classification, Gene Expression Regulation, Neoplastic, Disease Models, Animal, Biochemistry, Enzyme inhibitor, biology.protein, Disease Progression, Molecular Medicine, Pharmacophore, Kynurenine, HeLa Cells
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18
المؤلفون: Johnson Neil W, Michael Hansbury, Jerry L. Adams, Jim Winkler, Marcus Semones
المصدر: Bioorganicmedicinal chemistry letters. 17(20)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Ether, Biochemistry, Chemical synthesis, Methylation, Sensitivity and Specificity, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, In vivo, Drug Discovery, Potency, Imidazole, Molecular Biology, Protein Kinase Inhibitors, biology, Aryl, Organic Chemistry, Imidazoles, Sulfoxide, Receptor, TIE-2, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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19
المؤلفون: Peggy Scherle, Timothy Burn, Eddy W. Yue, Brent Douty, Yue Zhang, Yun-Long Li, Gengjie Yang, Liang-Chuan Wang, Michael Hansbury, Reid Huber, Gregory Hollis, Paul Waeltz, Nikoo Falahatpisheh, Holly Koblish, Thomas Maduskuie, Mark Rupar, Andrew P. Combs
المصدر: Molecular Cancer Therapeutics. 14:C103-C103
مصطلحات موضوعية: Cancer Research, business.industry, medicine.medical_treatment, T cell, FOXP3, Immunotherapy, Pharmacology, medicine.disease, Immune system, medicine.anatomical_structure, Oncology, Pancreatic cancer, medicine, Cytotoxic T cell, IL-2 receptor, business, CD8
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20
المؤلفون: Chu-Biao Xue, Holly Koblish, Peggy Scherle, Yun-Long Li, Michael Hansbury, Eddy W. Yue, Andrew P. Combs, Liang-Chuan S. Wang, Gengjie Yang, Reid Huber, Wenqing Yao, Taisheng Huang
المصدر: Cancer Research. 75:1336-1336
مصطلحات موضوعية: Cancer Research, Tumor microenvironment, Stromal cell, business.industry, medicine.medical_treatment, T cell, Immunotherapy, Pharmacology, medicine.disease, Immune checkpoint, Immune system, medicine.anatomical_structure, Oncology, Pancreatic cancer, Myeloid-derived Suppressor Cell, Medicine, business
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