المؤلفون: Andrew J. Kassick (5737691), Mariah Wu (11338099), Diego Luengas (11338102), Mohammad Ebqa’ai (11338105), L. P. Tharika Nirmani (11338108), Nestor Tomycz (11338111), Toby L. Nelson (2480176), Marco Pravetoni (491897), Michael D. Raleigh (11210435), Saadyah Averick (1247019)

مصطلحات موضوعية: Biophysics, Biochemistry, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Immunology, Mental Health, Chemical Sciences not elsewhere classified, mu opioid receptor antagonist naloxone, elimination half-life, c NLX-NP, naloxone chain end, nanoparticle-based naloxone formulation, OUD, Long-Acting Medical Countermeasure, Covalently Loaded Naloxone Nanopart., opioid use disorders

Relation: https://figshare.com/articles/journal_contribution/Covalently_Loaded_Naloxone_Nanoparticles_as_a_Long-Acting_Medical_Countermeasure_to_Opioid_Poisoning/16455190

الاتاحة: https://doi.org/10.1021/acsptsci.1c00168.s001

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/Measurement_of_ATI-1013_affinity_for_S-Nicotine_/15083051

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g001

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/Single_dose_nicotine_pharmacokinetics_in_rats_pre-treated_with_ATI-1012_or_ATI-1013_/15083057

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g003

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/Functional_i_in_vivo_i_activity_of_the_4_nic_mAbs_with_highest_affinity_for_nicotine_/15083054

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g002

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/Pharmacokinetics_of_ATI-1012_and_ATI-1013_in_rats_/15083060

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g004

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/Nicotine_self-administration_in_rats_treated_with_ATI-1013_/15083066

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g006

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/ATI-1013_alters_nicotine_distribution_to_serum_and_brain_following_repeated_administration_of_nicotine_/15083063

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g005

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/Distribution_of_ATI-1013_after_weekly_repeated_dosing_in_rats_/15083069

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g007

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/figure/Body_weight_over_time_in_toxicology_study_/15083072

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.g008

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/dataset/Affinity_of_the_10_most_potent_nicotine_binding_IgG1_mAbs_and_the_name_of_their_IgG4_isotype_counterparts_/15083075

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.t001

المؤلفون: Michael D. Raleigh (11210435), Nicola Beltraminelli (11210438), Stephanie Fallot (11210441), Mark G. LeSage (11210444), Amy Saykao (11210447), Paul R. Pentel (491898), Steve Fuller (7026716), Thomas Thisted (11210450), Zuzanna Biesova (11210453), Stephen Horrigan (11210456), Darryl Sampey (5435783), Bin Zhou (84959), Matthew W. Kalnik (11210459)

مصطلحات موضوعية: Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, binding affinity constants, nicotine binding antibodies, tobacco use disorder, Genes encoding 32, antibody, ATI, nicotine addiction, nicotine dosing experiment simulating, nicotine distribution, surface plasmon resonance, brain nicotine levels, nicotine pharmacokinetic experiments

Relation: https://figshare.com/articles/dataset/Antigen_selectivity_of_the_4_nic_mAbs_sup_A_sup_with_highest_affinity_for_S-_-nicotine_/15083078

الاتاحة: https://doi.org/10.1371/journal.pone.0254247.t002