المؤلفون: Campbell, Rianne R, Domingo, Racquel D, Williams, Amy R, Wroten, Melissa G, McGregor, Hadley A, Waltermire, Ryan S, Greentree, Daniel I, Goulding, Scott P, Thompson, Andrew B, Lee, Kaziya M, Quadir, Sema G, Chavez, C Leonardo Jimenez, Coelho, Michal A, Gould, Adam T, von Jonquieres, Georg, Klugmann, Matthias, Worley, Paul F, Kippin, Tod E, Szumlinski, Karen K

المصدر: Journal of Neuroscience. 39(14)

مصطلحات موضوعية: Behavioral and Social Science, Alcoholism, Alcohol Use and Health, Brain Disorders, Substance Misuse, Pediatric, Basic Behavioral and Social Science, Neurosciences, Underage Drinking, Stroke, Oral and gastrointestinal, Cardiovascular, Good Health and Well Being, Alcohol Drinking, Animals, Female, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Phosphorylation, Receptor, Metabotropic Glutamate 5, Septal Nuclei, anxiety, bed nucleus of the stria terminalis, binge-drinking, extracellular signal-regulated kinase, Homer protein, mGlu5 receptor, Medical and Health Sciences, Psychology and Cognitive Sciences, Neurology & Neurosurgery

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8jc4z0zr

المؤلفون: Aaron Dexter, Annika Lüttjohann, Gilles van Luijtelaar, Richard Ngomba, Swagat Ray

مصطلحات موضوعية: B230 - Pharmacy, epilepsy and sleep, metabotropic glutamate receptor 5, mGlu5 receptor allosteric modulators, sleep and wakefulness, thalamocortical oscillations

Relation: 10779/lincoln.24876600.v1; https://figshare.com/articles/journal_contribution/The_Metabotropic_Glutamate_5_Receptor_in_Sleep_and_Wakefulness_Focus_on_the_Cortico-Thalamo-Cortical_Oscillations/24876600

الاتاحة: https://figshare.com/articles/journal_contribution/The_Metabotropic_Glutamate_5_Receptor_in_Sleep_and_Wakefulness_Focus_on_the_Cortico-Thalamo-Cortical_Oscillations/24876600

المؤلفون: Torazza, Carola, Provenzano, Francesca, Gallia, Elena, Cerminara, Maria, Balbi, Matilde, Bonifacino, Tiziana, Tessitore, Sara, Ravera, Silvia, Usai, Cesare, Musante, Ilaria, Puliti, Aldamaria, Van Den Bosch, Ludo, Jafar-Nejad, Paymaan, Rigo, Frank, Milanese, Marco, Bonanno, Giambattista

المساهمون: Torazza, Carola, Provenzano, Francesca, Gallia, Elena, Cerminara, Maria, Balbi, Matilde, Bonifacino, Tiziana, Tessitore, Sara, Ravera, Silvia, Usai, Cesare, Musante, Ilaria, Puliti, Aldamaria, Van Den Bosch, Ludo, Jafar-Nejad, Paymaan, Rigo, Frank, Milanese, Marco, Bonanno, Giambattista

مصطلحات موضوعية: Grm5 genetic ablation, SOD1G93A mice, adult mouse spinal cord astrocyte, amyotrophic lateral sclerosi, mGlu5 receptor

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/37566031; info:eu-repo/semantics/altIdentifier/wos/WOS:001046187300001; volume:12:1952; firstpage:1; lastpage:28; numberofpages:28; journal:CELLS; https://hdl.handle.net/11567/1137558

الاتاحة: https://hdl.handle.net/11567/1137558
https://doi.org/10.3390/cells12151952

المؤلفون: Richard Teke Ngomba, Annika Lüttjohann, Aaron Dexter, Swagat Ray, Gilles van Luijtelaar

المصدر: Cells; Volume 12; Issue 13; Pages: 1761

مصطلحات موضوعية: sleep and wakefulness, metabotropic glutamate receptor 5, thalamocortical oscillations, epilepsy and sleep, mGlu5 receptor allosteric modulators

وصف الملف: application/pdf

Relation: Cellular Metabolism; https://dx.doi.org/10.3390/cells12131761

الاتاحة: https://doi.org/10.3390/cells12131761

المؤلفون: Matilde Balbi, Giambattista Bonanno, Tiziana Bonifacino, Marco Milanese

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5240

مصطلحات موضوعية: microglia, reactive phenotype, group I metabotropic glutamate receptors, mGlu5 receptor, mGlu1 receptor, mGluR5, mGluR1, amyotrophic lateral sclerosis, disease-associated microglia, DAM

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms24065240

الاتاحة: https://doi.org/10.3390/ijms24065240

المؤلفون: Cinzia Mallozzi, Rita Pepponi, Lucia Gaddini, Ida Casella, Valentina Chiodi, Patrizia Popoli, Maria Rosaria Domenici

المصدر: Biomolecules, Vol 13, Iss 9, p 1350 (2023)

مصطلحات موضوعية: adenosine A2A receptor, mGlu5 receptor, striatal-enriched protein tyrosine phosphatase (STEP), SH-SY5Y neuroblastoma cells, hippocampus, Microbiology, QR1-502

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2218-273X/13/9/1350; https://doaj.org/toc/2218-273X

URL الوصول: https://doaj.org/article/b3f21d9ad85b481b8f6bcae6ab01c4f2

المؤلفون: ANA ELENA TELEUCA, Giovanni Sebastiano Alemà, Paola Casolini, Ilaria Barberis, Francesco Ciabattoni, Rosamaria Orlando, Luisa Di Menna, Luisa Iacovelli, Maria Rosaria Scioli, Ferdinando Nicoletti, Anna Rita Zuena

المساهمون: Teleuca, ANA ELENA, Alema', Giovanni Sebastiano, Casolini, Paola, Barberis, Ilaria, Ciabattoni, Francesco, Orlando, Rosamaria, Di Menna, Luisa, Iacovelli, Luisa, Rosaria Scioli, Maria, Nicoletti, Ferdinando, Zuena, Anna Rita

مصطلحات موضوعية: Gαq, PLC-β, VU0360172, extinction, hippocampu, mGlu5 receptor, norbin, polyphosphoinositide hydrolysi, prefrontal cortex, spatial learning

Relation: info:eu-repo/semantics/altIdentifier/pmid/35330215; info:eu-repo/semantics/altIdentifier/wos/WOS:000774982700001; volume:12; issue:3; firstpage:463; numberofpages:16; journal:LIFE; http://hdl.handle.net/11573/1626466; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85127655864

الاتاحة: http://hdl.handle.net/11573/1626466
https://doi.org/10.3390/life12030463

المؤلفون: B. Di Marco, P. Dell'Albani, S. D'Antoni, M. Spatuzza, C.M. Bonaccorso, S.A. Musumeci, F. Drago, B. Bardoni, M.V. Catania

المصدر: Neurobiology of Disease, Vol 154, Iss , Pp 105338- (2021)

مصطلحات موضوعية: Stress granules, mGlu5 receptor, FMRP, Fragile X syndrome, eIF2alpha, Astrocytes, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996121000875; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/83288b34eb854add9bef0a55dd8d54c4

المؤلفون: Milanese, Marco, Bonifacino, Tiziana, Bertola, Nadia, Ferrando, Sara, Viale, Maurizio, Profumo, Aldo, Bonanno, Giambattista, Torazza, Carola, Provenzano, Francesca, Kumar, Mandeep, Ravera, Silvia, Zerbo, Arianna Roberta, Frumento, Giulia, Balbi, Matilde, Nguyen, Quynh Tram Julia

المصدر: British journal of pharmacology 178(18), 3747-3764 (2021). doi:10.1111/bph.15515

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Amyotrophic Lateral Sclerosis: drug therapy, Animals, Disease Models, Animal, Disease Progression, Female, Glutamic Acid, Male, Mice, Transgenic, Receptor, Metabotropic Glutamate 5, Spinal Cord, Superoxide Dismutase, Superoxide Dismutase-1: genetics, 2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine (CTEP), SOD1G93A mice, amyotrophic lateral sclerosis (ALS), in vivo pharmacological treatment, metabotropic glutamate receptor 5 (mGlu5 receptor)

جغرافية الموضوع: DE

Relation: info:eu-repo/semantics/altIdentifier/pmid/pmid:33931856; info:eu-repo/semantics/altIdentifier/issn/2056-8177; info:eu-repo/semantics/altIdentifier/issn/1476-5381; info:eu-repo/semantics/altIdentifier/issn/0007-1188; info:eu-repo/semantics/altIdentifier/issn/0366-0826; https://pub.dzne.de/record/155465; https://pub.dzne.de/search?p=id:%22DZNE-2021-00664%22

الاتاحة: https://pub.dzne.de/record/155465
https://pub.dzne.de/search?p=id:%22DZNE-2021-00664%22

المؤلفون: Isaias Lans, Óscar Díaz, James A. R. Dalton, Jesús Giraldo

المصدر: Frontiers in Molecular Biosciences, Vol 7 (2020)

مصطلحات موضوعية: G protein-coupled receptors, mGlu5 receptor, molecular dynamics computer simulation, potential of mean force calculations, free energies, mGlu, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fmolb.2020.00038/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/1e8feb3199bf4434bfe33b9803350628

المؤلفون: Simone Bossi, Ilaria Musante, Tommaso Bonfiglio, Tiziana Bonifacino, Laura Emionite, Maria Cerminara, Chiara Cervetto, Manuela Marcoli, Giambattista Bonanno, Roberto Ravazzolo, Anna Pittaluga, Aldamaria Puliti

المصدر: Neurobiology of Disease, Vol 109, Iss , Pp 44-53 (2018)

مصطلحات موضوعية: mGlu1 receptor, mGlu5 receptor, Grm1crv4 mouse, Ataxia, Evoked glutamate release, AMPA receptors, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996117302218; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/76f50a0b7ff949488e92e057707afacb

المؤلفون: Ricart-Ortega, Maria, Berizzi, Alice, Catena, Juanlo, Malhaire, Fanny, Muñoz, Lourdes, Serra, Carmen, Lebon, Guillaume, Goudet, Cyril, Llebaria, Amadeu

المساهمون: Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Institut de Química Avançada de Catalunya CSIC = Instituto de Química Avanzada de Cataluña CSIC = Institute of Advanced Chemistry of Catalonia CSIC (IQAC CSIC ), Consejo Superior de Investigaciones Cientificas España = Spanish National Research Council Spain (CSIC), ANR-10-LABX-0012,EpiGenMed,From Genome and Epigenome to Molecular Medicine: turning new paradigms in biology into the therapeutic strategies of tomorrow(2010), ANR-17-NEU3-0001,MAGNOLIA,Mglu4 AmyGdala NeurOmoduLatIon Autism(2017)

المصدر: ISSN: 1618-2642.

مصطلحات موضوعية: MPEP, MS binding assays, Radioligand binding assays, Saturation assay, mGlu5 receptor, [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biochemistry [q-bio.BM]

Relation: info:eu-repo/semantics/altIdentifier/pmid/32564119; PUBMED: 32564119

الاتاحة: https://hal.science/hal-02884945
https://hal.science/hal-02884945v1/document
https://hal.science/hal-02884945v1/file/Ricart-Ortega%20et%20al.%20Anal%20Bioanal%20Chemistry%202020.pdf
https://doi.org/10.1007/s00216-020-02772-9

المؤلفون: Celli R., Wall M. J., Santolini I., Vergassola M., Di Menna L., Mascio G., Cannella M., van Luijtelaar G., Pittaluga A., Ciruela F., Bruno V., Nicoletti F., Ngomba R. T.

المساهمون: Celli, R., Wall, M. J., Santolini, I., Vergassola, M., Di Menna, L., Mascio, G., Cannella, M., van Luijtelaar, G., Pittaluga, A., Ciruela, F., Bruno, V., Nicoletti, F., Ngomba, R. T.

مصطلحات موضوعية: GABA uptake, GAT-1, mGlu5 receptor, Somatosensory cortex, Tonic inhibition, Ventrobasal thalamus

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/32768418; info:eu-repo/semantics/altIdentifier/wos/WOS:000579490400003; volume:178; firstpage:108240; lastpage:108248; numberofpages:9; journal:NEUROPHARMACOLOGY; https://hdl.handle.net/11567/1036009; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85089702834

الاتاحة: https://hdl.handle.net/11567/1036009
https://doi.org/10.1016/j.neuropharm.2020.108240

المؤلفون: Lans, Isaias, Díaz Sanzo, Óscar, Dalton, James A. R., Giraldo, Jesús

مصطلحات موضوعية: G protein-coupled receptors, Mglu5 receptor, Molecular dynamics computer simulation, Potential of mean force calculations, Free energies, Mglu, Class C GPCR

وصف الملف: application/pdf

Relation: Ministerio de Economía y Competitividad SAF2014-58396-R; Ministerio de Ciencia e Innovación SAF2017-87199-R; Frontiers in Molecular Biosciences; Vol. 7 (march 2020); https://ddd.uab.cat/record/227685; urn:10.3389/fmolb.2020.00038; urn:oai:ddd.uab.cat:227685; urn:pmid:32211419; urn:pmcid:PMC7069277; urn:pmc-uid:7069277; urn:oai:pubmedcentral.nih.gov:7069277; urn:oai:egreta.uab.cat:publications/e83fe491-b974-48b7-921f-daa63200ca3a; urn:scopus_id:85082667516

الاتاحة: https://ddd.uab.cat/record/227685

المؤلفون: Marta Marszalek-Grabska, Kinga Gawel, Dariusz Matosiuk, Ewa Gibula-Tarlowska, Joanna Listos, Jolanta H. Kotlinska

المصدر: Biomolecules; Volume 10; Issue 5; Pages: 793

مصطلحات موضوعية: VU-29, mGlu5 receptor, positive allosteric modulator, conditioned place preference, ethanol, reward, memory

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/biom10050793

الاتاحة: https://doi.org/10.3390/biom10050793

المؤلفون: Giambattista Bonanno, Nadia Bertola, Giulia Frumento, Mandeep Kumar, T P Nhung Nguyen, Tiziana Bonifacino, Arianna Roberta Zerbo, Carola Torazza, Matilde Balbi, Maurizio Viale, Aldo Profumo, Sara Ferrando, Francesca Provenzano, Marco Milanese, Silvia Ravera

المصدر: British Journal of Pharmacology
British journal of pharmacology 178(18), 3747-3764 (2021). doi:10.1111/bph.15515

مصطلحات موضوعية: Male, amyotrophic lateral sclerosis (ALS), Allosteric modulator, 2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine (CTEP), Receptor, Metabotropic Glutamate 5, SOD1, Glutamic Acid, Mice, Transgenic, Pharmacology, Mice, Superoxide Dismutase-1, medicine, Animals, ddc:610, Amyotrophic lateral sclerosis, Receptor, 2‐chloro‐4‐((2,5‐dimethyl‐1‐(4‐(trifluoromethoxy)phenyl)‐1H‐imidazol‐4‐yl)ethynyl)pyridine (CTEP), metabotropic glutamate receptor 5 (mGlu5 receptor), drug therapy [Amyotrophic Lateral Sclerosis], Superoxide Dismutase, business.industry, Amyotrophic Lateral Sclerosis, 5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine (CTEP), Glutamate receptor, in vivo pharmacological treatment, Motor neuron, medicine.disease, Research Papers, genetics [Superoxide Dismutase-1], Disease Models, Animal, 2-chloro-4-((2, medicine.anatomical_structure, Spinal Cord, Metabotropic glutamate receptor, Disease Progression, Female, SOD1G93A mice, business, Research Paper, 2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine (CTEP), amyotrophic lateral sclerosis (ALS), in vivo pharmacological treatment, metabotropic glutamate receptor 5 (mGlu5 receptor), SOD1G93A mice, Astrocyte

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::805959c366c7fb322120e653e595c2b8
https://doi.org/10.1111/bph.15515

المؤلفون: Zuena Anna Rita, Iacovelli Luisa, Orlando Rosamaria, Di Menna Luisa, Casolini Paola, Alemà Giovanni Sebastiano, Di Cicco Gabriele, Battaglia Giuseppe, Nicoletti Ferdinando.

المساهمون: Zuena, Anna Rita, Iacovelli, Luisa, Orlando, Rosamaria, DI MENNA, Luisa, Casolini, Paola, Alema', Giovanni Sebastiano, DI CICCO, Gabriele, Battaglia, Giuseppe, Nicoletti, Ferdinando.

مصطلحات موضوعية: mGlu5 receptor, receptor signaling, polyphosphoinositide hydrolysi, InsP level, VU0360172, MTEP

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/30108503; info:eu-repo/semantics/altIdentifier/wos/WOS:000440317700002; volume:9; numberofpages:8; journal:FRONTIERS IN PHARMACOLOGY; http://hdl.handle.net/11573/1152789; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85070907351

الاتاحة: http://hdl.handle.net/11573/1152789
https://doi.org/10.3389/fphar.2018.00804

المؤلفون: Joan Font, Marc López-Cano, Serena Notartomaso, Pamela Scarselli, Paola Di Pietro, Roger Bresolí-Obach, Giuseppe Battaglia, Fanny Malhaire, Xavier Rovira, Juanlo Catena, Jesús Giraldo, Jean-Philippe Pin, Víctor Fernández-Dueñas, Cyril Goudet, Santi Nonell, Ferdinando Nicoletti, Amadeu Llebaria, Francisco Ciruela

المصدر: eLife, Vol 6 (2017)

مصطلحات موضوعية: analgesia, optopharmacology, pain neuraxis, mGlu5 receptor, allosteric modulation, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/23545; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/204af3c7e82a4250a352bd8ccbee7236

المؤلفون: Brambilla, Cláudia Régio

المساهمون: Neuner, Irene, Shah, Nadim Joni

المصدر: Aachen : RWTH Aachen University 1 Online-Ressource : Illustrationen (2022). doi:10.18154/RWTH-2022-02516 = Dissertation, Rheinisch-Westfälische Technische Hochschule Aachen, 2022

مصطلحات موضوعية: schizophrenia, schizophrenia , mGlu5 receptor , PET imaging , multimodal approach , mismatch negativity, mGlu5 receptor, PET imaging, mismatch negativity, multimodal approach, ddc:610

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd26ff8ff264a67bb2416935b7c30b9e

المؤلفون: Font, Joan, López-Cano, Marc, Notartomaso, Serena, Scarselli, Pamela, Di Pietro, Paola, Bresolí-Obach, Roger, Battaglia, Giuseppe, Malhaire, Fanny, Rovira, Xavier, Catena, Juanlo, Giraldo, Jesús, Pin, Jean-Philippe, Fernández-Dueñas, Víctor, Goudet, Cyril, Nonell, Santi, Nicoletti, Ferdinando, Llebaria, Amadeu, Ciruela, Francisco

المساهمون: Institut de Química Avançada de Catalunya CSIC = Instituto de Química Avanzada de Cataluña CSIC = Institute of Advanced Chemistry of Catalonia CSIC (IQAC CSIC ), Consejo Superior de Investigaciones Cientificas España = Spanish National Research Council Spain (CSIC), Universitat Autònoma de Barcelona = Autonomous University of Barcelona = Universidad Autónoma de Barcelona (UAB), Universitat de Barcelona (UB), Istituto Neurologico Mediterraneo (NEUROMED I.R.C.C.S.), Università degli Studi di Roma "La Sapienza" = Sapienza University Rome (UNIROMA)-University of Naples Federico II = Università degli studi di Napoli Federico II, Universitat Ramon Llull Barcelona (URL), Institut de Génomique Fonctionnelle (IGF), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Instituto de Salud Carlos III Madrid (ISCIII), Università degli Studi di Roma "La Sapienza" = Sapienza University Rome (UNIROMA)

المصدر: EISSN: 2050-084X ; eLife ; https://hal.science/hal-03549950 ; eLife, 2017, 6, ⟨10.7554/elife.23545.001⟩

مصطلحات موضوعية: allosteric modulation, analgesia, mGlu5 receptor, mouse, neuroscience, optopharmacology, pain neuraxis, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]

Relation: info:eu-repo/semantics/altIdentifier/pmid/28395733; PUBMED: 28395733; PUBMEDCENTRAL: PMC5388536

الاتاحة: https://hal.science/hal-03549950
https://hal.science/hal-03549950v1/document
https://hal.science/hal-03549950v1/file/2017%20Font%20et%20al%20eLIFE%20optical%20control%20of%20pain%20with%20a%20photoactive%20mGlu5%20NAM.pdf
https://doi.org/10.7554/elife.23545.001