المؤلفون: Borda, Victor, Loesch, Douglas, Guo, Bing, Laboulaye, Roland, Veliz-Otani, Diego, French, Jennifer, Leal, Thiago, Gogarten, Stephanie, Ikpe, Sunday, Gouveia, Mateus, Mendes, Marla, Abecasis, Gonçalo, Alvim, Isabela, Arboleda-Bustos, Carlos, Arboleda, Gonzalo, Arboleda, Humberto, Barreto, Mauricio, Barwick, Lucas, Bezzera, Marcos, Blangero, John, Borges, Vanderci, Caceres, Omar, Cai, Jianwen, Chana-Cuevas, Pedro, Chen, Zhanghua, Custer, Brian, Dean, Michael, Dinardo, Carla, Domingos, Igor, Duggirala, Ravindranath, Dieguez, Elena, Fernandez, Willian, Ferraz, Henrique, Gilliland, Frank, Guio, Heinner, Horta, Bernardo, Curran, Joanne, Johnsen, Jill, Kaplan, Robert, Kelly, Shannon, Kenny, Eimear, Konkle, Barbara, Kooperberg, Charles, Lescano, Andres, Lima-Costa, M, Loos, Ruth, Manichaikul, Ani, Meyers, Deborah, Naslavsky, Michel, Nickerson, Deborah, North, Kari, Padilla, Carlos, Preuss, Michael, Raggio, Victor, Reiner, Alexander, Rich, Stephen, Rieder, Carlos, Rienstra, Michiel, Rotter, Jerome, Rundek, Tatjana, Sacco, Ralph, Sanchez, Cesar, Sankaran, Vijay, Santos-Lobato, Bruno, Schumacher-Schuh, Artur, Scliar, Marilia, Silverman, Edwin, Sofer, Tamar, Lasky-Su, Jessica, Tumas, Vitor, Weiss, Scott, Mata, Ignacio, Hernandez, Ryan, Tarazona-Santos, Eduardo, OConnor, Timothy

المصدر: Cell Genomics. 4(11)

مصطلحات موضوعية: GLAD-match, GWAS, Latin America, identity-by-descent, imputation, local ancestry, migration, population structure, Humans, Latin America, Genetics, Population, Genome-Wide Association Study, Haplotypes, Algorithms, Genetic Variation, Software

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5dk8d1kt
https://escholarship.org/content/qt5dk8d1kt/qt5dk8d1kt.pdf

المؤلفون: Keener, Rebecca, Chhetri, Surya B, Connelly, Carla J, Taub, Margaret A, Conomos, Matthew P, Weinstock, Joshua, Ni, Bohan, Strober, Benjamin, Aslibekyan, Stella, Auer, Paul L, Barwick, Lucas, Becker, Lewis C, Blangero, John, Bleecker, Eugene R, Brody, Jennifer A, Cade, Brian E, Celedon, Juan C, Chang, Yi-Cheng, Cupples, L Adrienne, Custer, Brian, Freedman, Barry I, Gladwin, Mark T, Heckbert, Susan R, Hou, Lifang, Irvin, Marguerite R, Isasi, Carmen R, Johnsen, Jill M, Kenny, Eimear E, Kooperberg, Charles, Minster, Ryan L, Naseri, Take, Viali, Satupa’itea, Nekhai, Sergei, Pankratz, Nathan, Peyser, Patricia A, Taylor, Kent D, Telen, Marilyn J, Wu, Baojun, Yanek, Lisa R, Yang, Ivana V, Albert, Christine, Arnett, Donna K, Ashley-Koch, Allison E, Barnes, Kathleen C, Bis, Joshua C, Blackwell, Thomas W, Boerwinkle, Eric, Burchard, Esteban G, Carson, April P, Chen, Zhanghua, Chen, Yii-Der Ida, Darbar, Dawood, de Andrade, Mariza, Ellinor, Patrick T, Fornage, Myriam, Gelb, Bruce D, Gilliland, Frank D, He, Jiang, Islam, Talat, Kaab, Stefan, Kardia, Sharon LR, Kelly, Shannon, Konkle, Barbara A, Kumar, Rajesh, Loos, Ruth JF, Martinez, Fernando D, McGarvey, Stephen T, Meyers, Deborah A, Mitchell, Braxton D, Montgomery, Courtney G, North, Kari E, Palmer, Nicholette D, Peralta, Juan M, Raby, Benjamin A, Redline, Susan, Rich, Stephen S, Roden, Dan, Rotter, Jerome I, Ruczinski, Ingo, Schwartz, David, Sciurba, Frank, Shoemaker, M Benjamin, Silverman, Edwin K, Sinner, Moritz F, Smith, Nicholas L, Smith, Albert V, Tiwari, Hemant K, Vasan, Ramachandran S, Weiss, Scott T, Williams, L Keoki, Zhang, Yingze, Ziv, Elad, Raffield, Laura M, Reiner, Alexander P, Arvanitis, Marios, Greider, Carol W, Mathias, Rasika A, Battle, Alexis

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Biological Sciences, Genetics, Human Genome, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Generic health relevance, Humans, Genome-Wide Association Study, Telomere, K562 Cells, Telomere Homeostasis, Polymorphism, Single Nucleotide, Gene Expression Regulation, CRISPR-Cas Systems, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Hematology and Hemostasis Working Group, TOPMed Structural Variation Working Group

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6gg7t188
https://escholarship.org/content/qt6gg7t188/qt6gg7t188.pdf

المؤلفون: Everman, Jamie L, Sajuthi, Satria P, Liegeois, Maude A, Jackson, Nathan D, Collet, Erik H, Peters, Michael C, Chioccioli, Maurizio, Moore, Camille M, Patel, Bhavika B, Dyjack, Nathan, Powell, Roger, Rios, Cydney, Montgomery, Michael T, Eng, Celeste, Elhawary, Jennifer R, Mak, Angel CY, Hu, Donglei, Huntsman, Scott, Salazar, Sandra, Feriani, Luigi, Fairbanks-Mahnke, Ana, Zinnen, Gianna L, Michel, Cole R, Gomez, Joe, Zhang, Xing, Medina, Vivian, Chu, Hong Wei, Cicuta, Pietro, Gordon, Erin D, Zeitlin, Pamela, Ortega, Victor E, Reisdorph, Nichole, Dunican, Eleanor M, Tang, Monica, Elicker, Brett M, Henry, Travis S, Bleecker, Eugene R, Castro, Mario, Erzurum, Serpil C, Israel, Elliot, Levy, Bruce D, Mauger, David T, Meyers, Deborah A, Sumino, Kaharu, Gierada, David S, Hastie, Annette T, Moore, Wendy C, Denlinger, Loren C, Jarjour, Nizar N, Schiebler, Mark L, Wenzel, Sally E, Woodruff, Prescott G, Rodriguez-Santana, Jose, Pearson, Chad G, Burchard, Esteban G, Fahy, John V, Seibold, Max A

المصدر: Nature Communications. 15(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Asthma, Lung, Clinical Research, Genetics, 2.1 Biological and endogenous factors, Respiratory, Child, Humans, Cytokines, Epithelial Cells, GPI-Linked Proteins, Interleukin-13, Lectins, Mucin 5AC, Mucus, Nasal Mucosa, Polymorphism, Genetic, Respiratory Mucosa

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/21p3n4qj
https://escholarship.org/content/qt21p3n4qj/qt21p3n4qj.pdf

المؤلفون: Li, Xingnan, Li, Huashi, Christenson, Stephanie, Castro, Mario, Denlinger, Loren, Erzurum, Serpil, Fahy, John, Gaston, Benjamin, Israel, Elliot, Jarjour, Nizar, Levy, Bruce, Mauger, David, Moore, Wendy, Zein, Joe, Kaminski, Naftali, Wenzel, Sally, Woodruff, Prescott, Bleecker, Eugene, Meyers, Deborah

المصدر: The Journal of asthma research. 60(10)

مصطلحات موضوعية: Asthma susceptibility, MUC5AC, MUC5B, asthma severity, eQTL, gene expression, genetic association, Humans, Asthma, Genome-Wide Association Study, Cross-Sectional Studies, Phenotype, RNA, Messenger, Mucin-5B, Mucin 5AC

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1vt7f538
https://escholarship.org/content/qt1vt7f538/qt1vt7f538.pdf

المؤلفون: Li, Huashi, Castro, Mario, Denlinger, Loren, Erzurum, Serpil, Fahy, John, Gaston, Benjamin, Israel, Elliot, Jarjour, Nizar, Levy, Bruce, Mauger, David, Moore, Wendy, Wenzel, Sally, Zein, Joe, Bleecker, Eugene, Meyers, Deborah, Chen, Yin, Li, Xingnan

المصدر: The Journal of asthma research. 60(10)

مصطلحات موضوعية: Age of asthma onset, GSDMB, asthma subphenotypes, atopic asthma with fungal sensitization, non-atopic asthma, severe asthma, Child, Adult, Humans, Asthma, Hypersensitivity, Immediate, Longitudinal Studies, Biomarkers, Respiratory Function Tests

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6v09v2wf
https://escholarship.org/content/qt6v09v2wf/qt6v09v2wf.pdf

المؤلفون: Izquierdo, Manuel, Marion, Chad, Genese, Frank, Newell, John, ONeal, Wanda, Li, Xingnan, Hawkins, Gregory, Barjaktarevic, Igor, Barr, R, Christenson, Stephanie, Cooper, Christopher, Couper, David, Curtis, Jeffrey, Han, Meilan, Hansel, Nadia, Kanner, Richard, Martinez, Fernando, Paine, Robert, Tejwani, Vickram, Woodruff, Prescott, Zein, Joe, Hoffman, Eric, Peters, Stephen, Meyers, Deborah, Bleecker, Eugene, Ortega, Victor

المصدر: Chronic obstructive pulmonary diseases (Miami, Fla.). 10(3)

مصطلحات موضوعية: COPD, alpha-1 antitrypsin, bronchiectasis, lung function

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6pq2v8tf

المؤلفون: Weinstock, Joshua S, Laurie, Cecelia A, Broome, Jai G, Taylor, Kent D, Guo, Xiuqing, Shuldiner, Alan R, O’Connell, Jeffrey R, Lewis, Joshua P, Boerwinkle, Eric, Barnes, Kathleen C, Chami, Nathalie, Kenny, Eimear E, Loos, Ruth JF, Fornage, Myriam, Redline, Susan, Cade, Brian E, Gilliland, Frank D, Chen, Zhanghua, Gauderman, W James, Kumar, Rajesh, Grammer, Leslie, Schleimer, Robert P, Psaty, Bruce M, Bis, Joshua C, Brody, Jennifer A, Silverman, Edwin K, Yun, Jeong H, Qiao, Dandi, Weiss, Scott T, Lasky-Su, Jessica, DeMeo, Dawn L, Palmer, Nicholette D, Freedman, Barry I, Bowden, Donald W, Cho, Michael H, Vasan, Ramachandran S, Johnson, Andrew D, Yanek, Lisa R, Becker, Lewis C, Kardia, Sharon, He, Jiang, Kaplan, Robert, Heckbert, Susan R, Smith, Nicholas L, Wiggins, Kerri L, Arnett, Donna K, Irvin, Marguerite R, Tiwari, Hemant, Correa, Adolfo, Raffield, Laura M, Gao, Yan, de Andrade, Mariza, Rotter, Jerome I, Rich, Stephen S, Manichaikul, Ani W, Konkle, Barbara A, Johnsen, Jill M, Wheeler, Marsha M, Custer, Brian S, Duggirala, Ravindranath, Curran, Joanne E, Blangero, John, Gui, Hongsheng, Xiao, Shujie, Williams, L Keoki, Meyers, Deborah A, Li, Xingnan, Ortega, Victor, McGarvey, Stephen, Gu, C Charles, Chen, Yii-Der Ida, Lee, Wen-Jane, Shoemaker, M Benjamin, Darbar, Dawood, Roden, Dan, Albert, Christine, Kooperberg, Charles, Desai, Pinkal, Blackwell, Thomas W, Abecasis, Goncalo R, Smith, Albert V, Kang, Hyun M, Mathias, Rasika, Natarajan, Pradeep, Jaiswal, Siddhartha, Reiner, Alexander P, Bick, Alexander G, Consortium, NHLBI Trans-Omics for Precision Medicine

المصدر: Science Advances. 9(17)

مصطلحات موضوعية: Biological Sciences, Biomedical and Clinical Sciences, Genetics, Lung, Genetic Testing, Clinical Research, Biotechnology, Human Genome, 2.1 Biological and endogenous factors, Aetiology, Good Health and Well Being, Humans, Middle Aged, Hematopoiesis, Mutation, Germ-Line Mutation, Mutation, Missense, Phenotype, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1496g128
https://escholarship.org/content/qt1496g128/qt1496g128.pdf

المؤلفون: Fortis, Spyridon, Quibrera, Pedro M, Comellas, Alejandro P, Bhatt, Surya P, Tashkin, Donald P, Hoffman, Eric A, Criner, Gerard J, Han, MeiLan K, Barr, R Graham, Arjomandi, Mehrdad, Dransfield, Mark B, Peters, Stephen P, Dolezal, Brett A, Kim, Victor, Putcha, Nirupama, Rennard, Stephen I, Paine, Robert, Kanner, Richard E, Curtis, Jeffrey L, Bowler, Russell P, Martinez, Fernando J, Hansel, Nadia N, Krishnan, Jerry A, Woodruff, Prescott G, Barjaktarevic, Igor Z, Couper, David, Anderson, Wayne H, Cooper, Christopher B, Investigators, Subpopulations and Intermediate Outcome Measures in COPD Study, Alexis, Neil E, Barjaktarevic, Igor, Basta, Patricia, Bateman, Lori A, Bleecker, Eugene R, Boucher, Richard C, Christenson, Stephanie A, Couper, David J, Crystal, Ronald G, Doerschuk, Claire M, Dransfield, Mark T, Drummond, Brad, Freeman, Christine M, Galban, Craig, Hastie, Annette T, Huang, Yvonne, Kaner, Robert J, Kleerup, Eric C, LaVange, Lisa M, Lazarus, Stephen C, Meyers, Deborah A, Moore, Wendy C, Newell, John D, Paulin, Laura, Pirozzi, Cheryl, Oelsner, Elizabeth C, O’Neal, Wanda K, Ortega, Victor E, Raman, Sanjeev, Wells, J Michael, Wise, Robert A

المصدر: CHEST Journal. 163(3)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Asthma, Lung, Clinical Research, Chronic Obstructive Pulmonary Disease, Respiratory, Good Health and Well Being, Humans, Bronchodilator Agents, Retrospective Studies, Forced Expiratory Volume, Pulmonary Disease, Chronic Obstructive, Vital Capacity, Tobacco Products, bronchodilator, bronchodilator response, bronchodilator responsiveness, bronchodilator reversibility, COPD, Subpopulations and Intermediate Outcome Measures in COPD Study Investigators, Respiratory System, Cardiovascular medicine and haematology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5r25k2b6
https://escholarship.org/content/qt5r25k2b6/qt5r25k2b6.pdf

المؤلفون: Shrine, Nick, Izquierdo, Abril G., Chen, Jing, Packer, Richard, Hall, Robert J., Guyatt, Anna L., Batini, Chiara, Thompson, Rebecca J., Pavuluri, Chandan, Malik, Vidhi, Hobbs, Brian D., Moll, Matthew, Kim, Wonji, Tal-Singer, Ruth, Bakke, Per, Fawcett, Katherine A., John, Catherine, Coley, Kayesha, Piga, Noemi Nicole, Pozarickij, Alfred, Lin, Kuang, Millwood, Iona Y., Chen, Zhengming, Li, Liming, Wijnant, Sara R. A., Lahousse, Lies, Brusselle, Guy, Uitterlinden, Andre G., Manichaikul, Ani, Oelsner, Elizabeth C., Rich, Stephen S., Barr, R. Graham, Kerr, Shona M., Vitart, Veronique, Brown, Michael R., Wielscher, Matthias, Imboden, Medea, Jeong, Ayoung, Bartz, Traci M., Gharib, Sina A., Flexeder, Claudia, Karrasch, Stefan, Gieger, Christian, Peters, Annette, Stubbe, Beate, Hu, Xiaowei, Ortega, Victor E., Meyers, Deborah A., Bleecker, Eugene R., Gabriel, Stacey B., Gupta, Namrata, Smith, Albert Vernon, Luan, Jian'an, Zhao, Jing-Hua, Hansen, Ailin F., Langhammer, Arnulf, Willer, Cristen, Bhatta, Laxmi, Porteous, David, Smith, Blair H., Campbell, Archie, Sofer, Tamar, Lee, Jiwon, Daviglus, Martha L., Yu, Bing, Lim, Elise, Xu, Hanfei, O'Connor, George T., Thareja, Gaurav, Albagha, Omar M. E., Ismail, Said I., Al-Muftah, Wadha, Badji, Radja, Mbarek, Hamdi, Darwish, Dima, Fadl, Tasnim, Yasin, Heba, Ennaifar, Maryem, Abdellatif, Rania, Alkuwari, Fatima, Alvi, Muhammad, Al-Sarraj, Yasser, Saad, Chadi, Althani, Asmaa, Fethnou, Eleni, Qafoud, Fatima, Alkhayat, Eiman, Afifi, Nahla, Tomei, Sara, Liu, Wei, Lorenz, Stephan, Syed, Najeeb, Almabrazi, Hakeem, Vempalli, Fazulur Rehaman, Temanni, Ramzi, Abu Saqri, Tariq, Khatib, Mohammedhusen, Hamza, Mehshad, Abu Zaid, Tariq, El Khouly, Ahmed, Pathare, Tushar, Poolat, Shafeeq, Al-Ali, Rashid, Al-Khodor, Souhaila, Alshafai, Mashael, Badii, Ramin, Chouchane, Lotfi, Estivill, Xavier, Fakhro, Khalid, Mokrab, Younes, Puthen, Jithesh, V, Tatari, Zohreh, Suhre, Karsten, Granell, Raquel, Faquih, Tariq O., Hiemstra, Pieter S., Slats, Annelies M., Mullin, Benjamin H., Hui, Jennie, James, Alan, Beilby, John, Patasova, Karina, Hysi, Pirro, Koskela, Jukka T., Wyss, Annah B., Jin, Jianping, Sikdar, Sinjini, Lee, Mikyeong, May-Wilson, Sebastian, Pirastu, Nicola, Kentistou, Katherine A., Joshi, Peter K., Timmers, Paul R. H. J., Williams, Alexander T., Free, Robert C., Wang, Xueyang, Morrison, John L., Gilliland, Frank D., Chen, Zhanghua, Wang, Carol A., Foong, Rachel E., Harris, Sarah E., Taylor, Adele, Redmond, Paul, Cook, James P., Mahajan, Anubha, Lind, Lars, Palviainen, Teemu, Lehtimaki, Terho, Raitakari, Olli T., Kaprio, Jaakko, Rantanen, Taina, Pietilainen, Kirsi H., Cox, Simon R., Pennell, Craig E., Hall, Graham L., Gauderman, W. James, Brightling, Chris, Wilson, James F., Vasankari, Tuula, Laitinen, Tarja, Salomaa, Veikko, Mook-Kanamori, Dennis O., Timpson, Nicholas J., Zeggini, Eleftheria, Dupuis, Josee, Hayward, Caroline, Brumpton, Ben, Langenberg, Claudia, Weiss, Stefan, Homuth, Georg, Schmidt, Carsten Oliver, Probst-Hensch, Nicole, Jarvelin, Marjo-Riitta, Morrison, Alanna C., Polasek, Ozren, Rudan, Igor, Lee, Joo-Hyeon, Sayers, Ian, Rawlins, Emma L., Dudbridge, Frank, Silverman, Edwin K., Strachan, David P., Walters, Robin G., Morris, Andrew P., London, Stephanie J., Cho, Michael H., Wain, Louise V., Hall, Ian P., Tobin, Martin

المصدر: Nature Genetics. 55(3):410-422

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-509448
https://doi.org/10.1038/s41588-023-01314-0
https://uu.diva-portal.org/smash/get/diva2:1789381/FULLTEXT01.pdf

المؤلفون: Li, Xingnan, Guerra, Stefano, Ledford, Julie, Kraft, Monica, Li, Huashi, Hastie, Annette, Castro, Mario, Denlinger, Loren, Erzurum, Serpil, Fahy, John, Gaston, Benjamin, Israel, Elliot, Jarjour, Nizar, Levy, Bruce, Mauger, David, Moore, Wendy, Zein, Joe, Kaminski, Naftali, Wenzel, Sally, Woodruff, Prescott, Meyers, Deborah, Bleecker, Eugene

المصدر: American Journal of Respiratory and Critical Care Medicine. 207(4)

مصطلحات موضوعية: CC16, T2 inflammation, asthma exacerbations, asthma severity, bronchial epithelial cells, Humans, Asthma, Biomarkers, Epithelial Cells, Inflammation, Prospective Studies, Retrospective Studies, RNA, Messenger, Uteroglobin

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/29w7m351
https://escholarship.org/content/qt29w7m351/qt29w7m351.pdf

المؤلفون: Hill, Andrew C, Guo, Claire, Litkowski, Elizabeth M, Manichaikul, Ani W, Yu, Bing, Konigsberg, Iain R, Gorbet, Betty A, Lange, Leslie A, Pratte, Katherine A, Kechris, Katerina J, DeCamp, Matthew, Coors, Marilyn, Ortega, Victor E, Rich, Stephen S, Rotter, Jerome I, Gerzsten, Robert E, Clish, Clary B, Curtis, Jeffrey L, Hu, Xiaowei, Obeidat, Ma-en, Morris, Melody, Loureiro, Joseph, Ngo, Debby, O’Neal, Wanda K, Meyers, Deborah A, Bleecker, Eugene R, Hobbs, Brian D, Cho, Michael H, Banaei-Kashani, Farnoush, Bowler, Russell P

المصدر: Scientific Reports. 13(1)

مصطلحات موضوعية: Epidemiology, Biological Sciences, Health Sciences, Genetics, Atherosclerosis, Cardiovascular, Minority Health, Health Disparities, Human Genome, Biotechnology, Generic health relevance, Humans, Proteome, Bayes Theorem, Privacy, Genome-Wide Association Study, Polymorphism, Single Nucleotide

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6jt046f6
https://escholarship.org/content/qt6jt046f6/qt6jt046f6.pdf

المؤلفون: Peters, Michael C, Schiebler, Mark L, Cardet, Juan Carlos, Johansson, Mats W, Sorkness, Ronald, DeBoer, Mark D, Bleecker, Eugene R, Meyers, Deborah A, Castro, Mario, Sumino, Kaharu, Erzurum, Serpil C, Tattersall, Matthew C, Zein, Joe G, Hastie, Annette T, Moore, Wendy, Levy, Bruce D, Israel, Elliot, Duvall, Melody G, Phillips, Brenda R, Mauger, David T, Wenzel, Sally E, Fajt, Merritt L, Koliwad, Suneil K, Denlinger, Loren C, Woodruff, Prescott G, Jarjour, Nizar N, Fahy, John V, Schiebler, Mark, Carlos Cardet, Juan, Duvall, Melody

المصدر: American Journal of Respiratory and Critical Care Medicine. 206(9)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Clinical Trials and Supportive Activities, Clinical Research, Lung, Asthma, Obesity, Respiratory, Humans, Insulin Resistance, Cross-Sectional Studies, Bronchodilator Agents, Adrenal Cortex Hormones, Forced Expiratory Volume, asthma, obesity, insulin resistance, lung function, National Heart, Lung, and Blood Institute Severe Asthma Research Program-3, Medical and Health Sciences, Respiratory System, Cardiovascular medicine and haematology, Clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6h28g1dv

المؤلفون: Jang, Seon-Kyeong, Evans, Luke, Fialkowski, Allison, Arnett, Donna K, Ashley-Koch, Allison E, Barnes, Kathleen C, Becker, Diane M, Bis, Joshua C, Blangero, John, Bleecker, Eugene R, Boorgula, Meher Preethi, Bowden, Donald W, Brody, Jennifer A, Cade, Brian E, Jenkins, Brenda W Campbell, Carson, April P, Chavan, Sameer, Cupples, L Adrienne, Custer, Brian, Damrauer, Scott M, David, Sean P, de Andrade, Mariza, Dinardo, Carla L, Fingerlin, Tasha E, Fornage, Myriam, Freedman, Barry I, Garrett, Melanie E, Gharib, Sina A, Glahn, David C, Haessler, Jeffrey, Heckbert, Susan R, Hokanson, John E, Hou, Lifang, Hwang, Shih-Jen, Hyman, Matthew C, Judy, Renae, Justice, Anne E, Kaplan, Robert C, Kardia, Sharon LR, Kelly, Shannon, Kim, Wonji, Kooperberg, Charles, Levy, Daniel, Lloyd-Jones, Donald M, Loos, Ruth JF, Manichaikul, Ani W, Gladwin, Mark T, Martin, Lisa Warsinger, Nouraie, Mehdi, Melander, Olle, Meyers, Deborah A, Montgomery, Courtney G, North, Kari E, Oelsner, Elizabeth C, Palmer, Nicholette D, Payton, Marinelle, Peljto, Anna L, Peyser, Patricia A, Preuss, Michael, Psaty, Bruce M, Qiao, Dandi, Rader, Daniel J, Rafaels, Nicholas, Redline, Susan, Reed, Robert M, Reiner, Alexander P, Rich, Stephen S, Rotter, Jerome I, Schwartz, David A, Shadyab, Aladdin H, Silverman, Edwin K, Smith, Nicholas L, Smith, J Gustav, Smith, Albert V, Smith, Jennifer A, Tang, Weihong, Taylor, Kent D, Telen, Marilyn J, Vasan, Ramachandran S, Gordeuk, Victor R, Wang, Zhe, Wiggins, Kerri L, Yanek, Lisa R, Yang, Ivana V, Young, Kendra A, Young, Kristin L, Zhang, Yingze, Liu, Dajiang J, Keller, Matthew C, Vrieze, Scott

المصدر: Nature human behaviour. 6(11)

مصطلحات موضوعية: Smoking, Gene Frequency, Phenotype, Polymorphism, Single Nucleotide, Genome-Wide Association Study, Tobacco, Genetics, Tobacco Smoke and Health, Human Genome, Cancer

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3v26257d

المؤلفون: Cardet, Juan, Kim, Donghwa, Bleecker, Eugene, Casale, Thomas, Israel, Elliot, Mauger, David, Meyers, Deborah, Ampleford, Elizabeth, Hawkins, Gregory, Tu, Yaping, Liggett, Stephen, Ortega, Victor

المصدر: Journal of Allergy and Clinical Immunology. 150(3)

مصطلحات موضوعية: G protein–coupled receptors, Regulator of G protein signaling, airway hyperresponsiveness, airway smooth muscle, asthma exacerbations, bronchoconstriction, endotype, genomics, genotype, phenotype, Animals, Asthma, Histamine, Humans, Mice, Polymorphism, Single Nucleotide, Promoter Regions, Genetic, Prospective Studies, RGS Proteins, RNA, Small Interfering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2ch7v85h

المؤلفون: Izquierdo, Manuel E, Marion, Chad R, Moore, Wendy C, Raraigh, Karen S, Taylor-Cousar, Jennifer L, Cutting, Gary R, Ampleford, E, Hawkins, Gregory A, Zein, Joe, Castro, M, Denlinger, Loren C, Erzurum, Serpil C, Fahy, John V, Israel, Elliot, Jarjour, Nizar N, Mauger, David, Levy, Bruce D, Wenzel, Sally E, Woodruff, Prescott, Bleecker, Eugene R, Meyers, Deborah A, Ortega, Victor E

المصدر: Pediatric Pulmonology. 57(7)

مصطلحات موضوعية: Paediatrics, Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Asthma, Lung, Rare Diseases, Cystic Fibrosis, Genetics, Aetiology, 2.1 Biological and endogenous factors, Congenital, Good Health and Well Being, Cystic Fibrosis Transmembrane Conductance Regulator, Humans, Mutation, Sequence Analysis, DNA, CF-Asthma Overlap, CFTR, cystic fibrosis, heterozygote carriers, Paediatrics and Reproductive Medicine, Respiratory System, Cardiovascular medicine and haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1hg0z69r

المؤلفون: Hu, Xiaowei, Qiao, Dandi, Kim, Wonji, Moll, Matthew, Balte, Pallavi P, Lange, Leslie A, Bartz, Traci M, Kumar, Rajesh, Li, Xingnan, Yu, Bing, Cade, Brian E, Laurie, Cecelia A, Sofer, Tamar, Ruczinski, Ingo, Nickerson, Deborah A, Muzny, Donna M, Metcalf, Ginger A, Doddapaneni, Harshavardhan, Gabriel, Stacy, Gupta, Namrata, Dugan-Perez, Shannon, Cupples, L Adrienne, Loehr, Laura R, Jain, Deepti, Rotter, Jerome I, Wilson, James G, Psaty, Bruce M, Fornage, Myriam, Morrison, Alanna C, Vasan, Ramachandran S, Washko, George, Rich, Stephen S, O’Connor, George T, Bleecker, Eugene, Kaplan, Robert C, Kalhan, Ravi, Redline, Susan, Gharib, Sina A, Meyers, Deborah, Ortega, Victor, Dupuis, Josée, London, Stephanie J, Lappalainen, Tuuli, Oelsner, Elizabeth C, Silverman, Edwin K, Barr, R Graham, Thornton, Timothy A, Wheeler, Heather E, Group, TOPMed Lung Working, Cho, Michael H, Im, Hae Kyung, Manichaikul, Ani

المصدر: American Journal of Human Genetics. 109(5)

مصطلحات موضوعية: Epidemiology, Biological Sciences, Health Sciences, Genetics, Clinical Research, Lung, Prevention, Tobacco, Chronic Obstructive Pulmonary Disease, Tobacco Smoke and Health, Respiratory, Good Health and Well Being, Humans, National Heart, Lung, and Blood Institute (U.S.), Pulmonary Disease, Chronic Obstructive, Risk Factors, Transcriptome, United States, TOPMed Lung Working Group, cross-ethnic portability, gene expression, integrative analysis, polygenic transcriptome risk score, pulmonary disease, risk prediction, Medical and Health Sciences, Genetics & Heredity, Biological sciences, Biomedical and clinical sciences, Health sciences

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URL الوصول: https://escholarship.org/uc/item/6vn9w4g7

المؤلفون: Esther, Charles R, O’Neal, Wanda K, Anderson, Wayne H, Kesimer, Mehmet, Ceppe, Agathe, Doerschuk, Claire M, Alexis, Neil E, Hastie, Annette T, Barr, R Graham, Bowler, Russell P, Wells, J Michael, Oelsner, Elizabeth C, Comellas, Alejandro P, Tesfaigzi, Yohannes, Kim, Victor, Paulin, Laura M, Cooper, Christopher B, Han, MeiLan K, Huang, Yvonne J, Labaki, Wassim W, Curtis, Jeffrey L, Boucher, Richard C, Study, Subpopulations and Intermediate Outcome Measures in COPD, Arjomandi, Mehrdad, Barjaktarevic, Igor, Bateman, Lori A, Bhatt, Surya P, Bleecker, Eugene R, Christenson, Stephanie A, Couper, David J, Criner, Gerard J, Crystal, Ronald G, Dransfield, Mark T, Drummond, Brad, Freeman, Christine M, Galban, Craig, Hansel, Nadia N, Hoffman, Eric A, Huang, Yvonne, Kaner, Robert J, Kanner, Richard E, Kleerup, Eric C, Krishnan, Jerry A, LaVange, Lisa M, Lazarus, Stephen C, Martinez, Fernando J, Meyers, Deborah A, Moore, Wendy C, Newell, John D, Paine, Robert, Paulin, Laura, Peters, Stephen P, Pirozzi, Cheryl, Putcha, Nirupama, Ortega, Victor E, Raman, Sanjeev, Rennard, Stephen I, Tashkin, Donald P, Wise, Robert A, Woodruff, Prescott G

المصدر: CHEST Journal. 161(5)

مصطلحات موضوعية: Lung, Chronic Obstructive Pulmonary Disease, Clinical Research, Respiratory, Good Health and Well Being, Biomarkers, Humans, Hypoxanthines, N-Acetylneuraminic Acid, Pulmonary Disease, Chronic Obstructive, Sputum, adenosine, glutathione, inflammation, metabolomics, methionine salvage, mucus, Subpopulations and Intermediate Outcome Measures in COPD Study, Clinical Sciences, Respiratory System

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URL الوصول: https://escholarship.org/uc/item/1h68k61b

المؤلفون: Nakao, Tetsushi, Bick, Alexander G, Taub, Margaret A, Zekavat, Seyedeh M, Uddin, Md M, Niroula, Abhishek, Carty, Cara L, Lane, John, Honigberg, Michael C, Weinstock, Joshua S, Pampana, Akhil, Gibson, Christopher J, Griffin, Gabriel K, Clarke, Shoa L, Bhattacharya, Romit, Assimes, Themistocles L, Emery, Leslie S, Stilp, Adrienne M, Wong, Quenna, Broome, Jai, Laurie, Cecelia A, Khan, Alyna T, Smith, Albert V, Blackwell, Thomas W, Codd, Veryan, Nelson, Christopher P, Yoneda, Zachary T, Peralta, Juan M, Bowden, Donald W, Irvin, Marguerite R, Boorgula, Meher, Zhao, Wei, Yanek, Lisa R, Wiggins, Kerri L, Hixson, James E, Gu, C Charles, Peloso, Gina M, Roden, Dan M, Reupena, Muagututi’a S, Hwu, Chii-Min, DeMeo, Dawn L, North, Kari E, Kelly, Shannon, Musani, Solomon K, Bis, Joshua C, Lloyd-Jones, Donald M, Johnsen, Jill M, Preuss, Michael, Tracy, Russell P, Peyser, Patricia A, Qiao, Dandi, Desai, Pinkal, Curran, Joanne E, Freedman, Barry I, Tiwari, Hemant K, Chavan, Sameer, Smith, Jennifer A, Smith, Nicholas L, Kelly, Tanika N, Hidalgo, Bertha, Cupples, L Adrienne, Weeks, Daniel E, Hawley, Nicola L, Minster, Ryan L, Deka, Ranjan, Naseri, Take T, de las Fuentes, Lisa, Raffield, Laura M, Morrison, Alanna C, Vries, Paul S, Ballantyne, Christie M, Kenny, Eimear E, Rich, Stephen S, Whitsel, Eric A, Cho, Michael H, Shoemaker, M Benjamin, Pace, Betty S, Blangero, John, Palmer, Nicholette D, Mitchell, Braxton D, Shuldiner, Alan R, Barnes, Kathleen C, Redline, Susan, Kardia, Sharon LR, Abecasis, Gonçalo R, Becker, Lewis C, Heckbert, Susan R, He, Jiang, Post, Wendy, Arnett, Donna K, Vasan, Ramachandran S, Darbar, Dawood, Weiss, Scott T, McGarvey, Stephen T, de Andrade, Mariza, Chen, Yii-Der Ida, Kaplan, Robert C, Meyers, Deborah A, Custer, Brian S, Correa, Adolfo

المصدر: Science Advances. 8(14)

مصطلحات موضوعية: Cardiovascular, Genetics, Aging, Heart Disease, Heart Disease - Coronary Heart Disease, Human Genome, Atherosclerosis, Aetiology, 2.1 Biological and endogenous factors, Good Health and Well Being, Samoan Obesity, Lifestyle and Genetic Adaptations Study (OLaGA) Group, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium

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URL الوصول: https://escholarship.org/uc/item/8qf1z3bm

المؤلفون: O’Toole, Jacqueline, Woo, Han, Putcha, Nirupama, Cooper, Christopher B, Woodruff, Prescott, Kanner, Richard E, Paine, Robert, Bowler, Russell P, Comellas, Alejandro, Hoth, Karin F, Krishnan, Jerry A, Han, Meilan, Dransfield, Mark, Iyer, Anand S, Couper, David, Peters, Stephen P, Criner, Gerard, Kim, Victor, Barr, R Graham, Martinez, Fernando J, Hansel, Nadia N, Eakin, Michelle N, Alexis, Neil E, Anderson, Wayne H, Arjomandi, Mehrdad, Barjaktarevic, Igor, Bateman, Lori A, Bhatt, Surya P, Bleecker, Eugene R, Boucher, Richard C, Christenson, Stephanie A, Comellas, Alejandro P, Couper, David J, Criner, Gerard J, Crystal, Ronald G, Curtis, Jeffrey L, Doerschuk, Claire M, Dransfield, Mark T, Drummond, Brad, Freeman, Christine M, Galban, Craig, Han, MeiLan K, Hastie, Annette T, Hoffman, Eric A, Huang, Yvonne, Kaner, Robert J, Kleerup, Eric C, LaVange, Lisa M, Lazarus, Stephen C, Meyers, Deborah A, Moore, Wendy C, Newell, John D, Paulin, Laura, Pirozzi, Cheryl, Oelsner, Elizabeth C, O’Neal, Wanda K, Ortega, Victor E, Raman, Sanjeev, Rennard, Stephen I, Tashkin, Donald P, Wells, J Michael, Wise, Robert A, Woodruff, Prescott G

المصدر: Annals of the American Thoracic Society. 19(2)

مصطلحات موضوعية: Clinical Research, Behavioral and Social Science, Depression, Chronic Obstructive Pulmonary Disease, Mental Health, Lung, Respiratory, Good Health and Well Being, Female, Forced Expiratory Volume, Humans, Pulmonary Disease, Chronic Obstructive, Quality of Life, Respiratory Function Tests, Smoking, Surveys and Questionnaires, depression, COPD, patient reported outcome measures, SPIROMICS Investigators

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URL الوصول: https://escholarship.org/uc/item/01b8r6nx

المؤلفون: Georas, Steve N, Wright, Rosalind J, Ivanova, Anastasia, Israel, Elliot, LaVange, Lisa M, Akuthota, Praveen, Carr, Tara F, Denlinger, Loren C, Fajt, Merritt L, Kumar, Rajesh, O’Neal, Wanda K, Phipatanakul, Wanda, Szefler, Stanley J, Aronica, Mark A, Bacharier, Leonard B, Burbank, Allison J, Castro, Mario, Alexander, Laura Crotty, Bamdad, Julie, Cardet, Juan Carlos, Comhair, Suzy AA, Covar, Ronina A, DiMango, Emily A, Erwin, Kim, Erzurum, Serpil C, Fahy, John V, Gaffin, Jonathan M, Gaston, Benjamin, Gerald, Lynn B, Hoffman, Eric A, Holguin, Fernando, Jackson, Daniel J, James, John, Jarjour, Nizar N, Kenyon, Nicholas J, Khatri, Sumita, Kirwan, John P, Kraft, Monica, Krishnan, Jerry A, Liu, Andrew H, Liu, Mark C, Marquis, M Alison, Martinez, Fernando, Mey, Jacob, Moore, Wendy C, Moy, James N, Ortega, Victor E, Peden, David B, Pennington, Emily, Peters, Michael C, Ross, Kristie, Sanchez, Maria, Smith, Lewis J, Sorkness, Ronald L, Wechsler, Michael E, Wenzel, Sally E, White, Steven R, Zein, Joe, Zeki, Amir A, Noel, Patricia, Billheimer, Dean, Bleecker, Eugene R, Branch, Emily, Conway, Michelle, Daines, Cori, Deaton, Isaac, Evans, Alexandria, Field, Paige, Francisco, Dave, Hastie, Annette T, Hmieleski, Bob, Krings, Jeffrey O, Liu, Yanqin, Merchen, Janell L, Meyers, Deborah A, Narendran, Nirushan, Peters, Stephen P, Pippins, Anna, Rank, Matthew A, Schunk, Ronald, Skeps, Raymond, Wright, Benjamin, Banzon, Tina M, Bartnikas, Lisa M, Baxi, Sachin N, Betapudi, Vishwanath, Brick, Isabelle, Brockway, Conor, Casale, Thomas B, Castillo-Ruano, Kathleen, Cinelli, Maria Angeles, Crestani, Elena, Cunningham, Amparito, Day-Lewis, Megan, Diaz-Cabrera, Natalie, DiMango, Angela, Esty, Brittany, Fandozzi, Eva, Fernandez, Jesse, Fitzpatrick, Elizabeth

المصدر: Journal of Allergy and Clinical Immunology. 149(2)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Lung, Asthma, Precision Medicine, Clinical Trials and Supportive Activities, Clinical Research, Respiratory, Good Health and Well Being, Advisory Committees, Biomarkers, Clinical Protocols, Clinical Trials, Phase II as Topic, Humans, Research Design, Severity of Illness Index, Tomography, X-Ray Computed, Severe asthma, precision medicine, adaptive clinical trial design, asthma exacerbation, type 2 asthma, non-type 2 asthma, patient advisory committee, biomarker, PrecISE Study Team, non–type 2 asthma, Immunology, Allergy

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/4n8620m5
https://escholarship.org/content/qt4n8620m5/qt4n8620m5.pdf