المؤلفون: de Vries, Sieta T, de Vos, Stijn, Oktora, Monika P, Denig, Petra

المصدر: de Vries , S T , de Vos , S , Oktora , M P & Denig , P 2024 , ' Sex disparities in medication changes after metformin initiation are associated with small, clinically non-relevant, sex differences in HbA1c levels during follow-up ' , Pharmacoepidemiology and Drug Safety , vol. 33 , no. 5 , e5802 . https://doi.org/10.1002/pds.5802

مصطلحات موضوعية: Humans, Metformin/administration & dosage, Glycated Hemoglobin/analysis, Female, Hypoglycemic Agents/administration & dosage, Male, Diabetes Mellitus, Type 2/drug therapy, Sex Factors, Follow-Up Studies, Middle Aged, Aged

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/77b9c9ee-080a-4fc3-8f22-6568c1011d6c
https://research.rug.nl/en/publications/77b9c9ee-080a-4fc3-8f22-6568c1011d6c
https://doi.org/10.1002/pds.5802
https://pure.rug.nl/ws/files/1004812379/Pharmacoepidemiology_and_Drug_-_2024_-_Vries_-_Sex_disparities_in_medication_changes_after_metformin_initiation_are.pdf

المؤلفون: Chaudhari, Kiran, Wang, Jianmei, Xu, Yong, Winters, Ali, Wang, Linshu, Dong, Xiaowei, Cheng, Eric Y., Liu, Ran, Yang, Shaohua

المصدر: PLoS One

مصطلحات موضوعية: Animals, Brain / metabolism, Chromatography, Liquid, Female, Kidney / metabolism, Liver / metabolism, Male, Metformin / administration & dosage, Metformin / blood, Metformin / pharmacokinetics, Mice, Inbred C57BL, Muscles / metabolism, Tandem Mass Spectrometry, Tissue Distribution

وصف الملف: application/pdf

Relation: https://doi.org/10.1371/journal.pone.0234571; Chaudhari, K., Wang, J., Xu, Y., Winters, A., Wang, L., Dong, X., Cheng, E. Y., Liu, R., & Yang, S. H. (2020). Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm. PloS one, 15(6), e0234571. https://doi.org/10.1371/journal.pone.0234571; https://hdl.handle.net/20.500.12503/31984; 15

الاتاحة: https://hdl.handle.net/20.500.12503/31984

المؤلفون: Raggi, Chiara, Taddei, Maria Letizia, Sacco, Elena, Navari, Nadia, Correnti, Margherita, Piombanti, Benedetta, Pastore, Mirella, Campani, Claudia, Pranzini, Erica, Iorio, Jessica, Lori, Giulia, Lottini, Tiziano, Peano, Clelia, Cibella, Javier, Lewinska, Monika, Andersen, Jesper B, di Tommaso, Luca, Viganò, Luca, Di Maira, Giovanni, Madiai, Stefania, Ramazzotti, Matteo, Orlandi, Ivan, Arcangeli, Annarosa, Chiarugi, Paola, Marra, Fabio

المصدر: Raggi , C , Taddei , M L , Sacco , E , Navari , N , Correnti , M , Piombanti , B , Pastore , M , Campani , C , Pranzini , E , Iorio , J , Lori , G , Lottini , T , Peano , C , Cibella , J , Lewinska , M , Andersen , J B , di Tommaso , L , Viganò , L , Di Maira , G , Madiai , S , Ramazzotti , M , Orlandi , I , Arcangeli , A , Chiarugi , P ....

مصطلحات موضوعية: Animals, Bile Duct Neoplasms/drug therapy, Carcinogenesis/drug effects, Cell Line, Tumor, Cholangiocarcinoma/drug therapy, Electron Transport Complex II/metabolism, Epithelial-Mesenchymal Transition/drug effects, Gene Silencing, Humans, Indoles/administration & dosage, Male, Metformin/administration & dosage, Mice, Inbred NOD, SCID, Mitochondria/metabolism, Neoplastic Stem Cells/metabolism, Oxidative Phosphorylation/drug effects, Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/antagonists & inhibitors, Phenotype, Progression-Free Survival, Propanols/administration & dosage, Signal Transduction/drug effects, Transfection, Treatment Outcome, Tumor Burden/drug effects, Xenograft Model Antitumor Assays

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/mitochondrial-oxidative-metabolism-contributes-to-a-cancer-stem-cell-phenotype-in-cholangiocarcinoma(ffe0465b-8987-4d6c-a47c-694d81d5a369).html
https://doi.org/10.1016/j.jhep.2020.12.031
https://curis.ku.dk/ws/files/333036705/mitochondrial_oxidative_metabolism_in_cca.pdf

المؤلفون: Lauritzen, Elisabeth, Hebbelstrup Jensen, David, Bonde, Christian, Beck-Nielsen, Henning

المصدر: Ugeskrift for Laeger. 181(17):1618

المؤلفون: Stage, Tore Bjerregaard, Wellhagen, Gustaf, Christensen, Mette Marie Hougaard, Guiastrennec, Benjamin, Brøsen, Kim, Kjellsson, Maria C

المصدر: Stage , T B , Wellhagen , G , Christensen , M M H , Guiastrennec , B , Brøsen , K & Kjellsson , M C 2019 , ' Using a semi-mechanistic model to identify the main sources of variability of metformin pharmacokinetics ' , Basic & Clinical Pharmacology & Toxicology , vol. 124 , no. 1 , pp. 105-114 . https://doi.org/10.1111/bcpt.13139

مصطلحات موضوعية: Acidosis, Lactic/chemically induced, Administration, Oral, Adult, Biological Availability, Biological Variation, Individual, Population/physiology, Clinical Trials as Topic, Gastrointestinal Absorption/physiology, Gastrointestinal Transit/physiology, Healthy Volunteers, Humans, Hypoglycemic Agents/administration & dosage, Metformin/administration & dosage, Middle Aged, Models, Biological, Organic Cation Transport Proteins/genetics, Pharmacogenomic Variants, Polymorphism, Single Nucleotide, Time Factors, Young Adult

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/a1815011-6077-4490-9fa7-b37e5f715afb

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/a1815011-6077-4490-9fa7-b37e5f715afb
https://doi.org/10.1111/bcpt.13139
https://findresearcher.sdu.dk/ws/files/146453151/Using_a_semi_mechanistic_model_to_identify_the_main_sources_of_variability_of_metformin_pharmacokinetics.pdf

المؤلفون: Sterner, Gunnar, Frid, Anders

المصدر: Läkartidningen. 115(15):656

المؤلفون: Underdal, Maria Othelie, Stridsklev, Solhild, Oppen, Ingrid Hennum, Høgetveit, Kristin, Andersen, Marianne Skovsager, Vanky, Eszter

المصدر: Underdal , M O , Stridsklev , S , Oppen , I H , Høgetveit , K , Andersen , M S & Vanky , E 2018 , ' Does Metformin Treatment during Pregnancy Modify the Future Metabolic Profile in Women with PCOS? ' , The Journal of Clinical Endocrinology & Metabolism , vol. 103 , no. 6 , pp. 2408–2413 . https://doi.org/10.1210/jc.2018-00485

مصطلحات موضوعية: Adult, Blood Glucose, Blood Pressure/drug effects, Body Mass Index, Female, Follow-Up Studies, Humans, Hypoglycemic Agents/administration & dosage, Insulin Resistance/physiology, Insulin/blood, Lipids/blood, Metformin/administration & dosage, Polycystic Ovary Syndrome/blood, Pregnancy, Pregnancy Complications/blood, Pregnancy Trimester, First, Waist Circumference/drug effects

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/81fc7a35-1e2a-4cb8-9b18-d8961f6e4f11

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/81fc7a35-1e2a-4cb8-9b18-d8961f6e4f11
https://doi.org/10.1210/jc.2018-00485
https://findresearcher.sdu.dk/ws/files/140659276/Does_metformin_treatment_during_pregnancy_modify_future_metabolic_profile_in_women_with_PCOS.pdf

المؤلفون: Athanasiou, Dimitra, Aguila, Monica, Opefi, Chikwado A, South, Kieron, Bellingham, James, Bevilacqua, Dalila, Munro, Peter M, Kanuga, Naheed, Mackenzie, Francesca E, Dubis, Adam M, Georgiadis, Anastasios, Graca, Anna B, Pearson, Rachael A, Ali, Robin R, Sakami, Sanae, Palczewski, Krzysztof, Sherman, Michael Y, Reeves, Philip J, Cheetham, Michael E

المصدر: Athanasiou , D , Aguila , M , Opefi , C A , South , K , Bellingham , J , Bevilacqua , D , Munro , P M , Kanuga , N , Mackenzie , F E , Dubis , A M , Georgiadis , A , Graca , A B , Pearson , R A , Ali , R R , Sakami , S , Palczewski , K , Sherman , M Y , Reeves , P J & Cheetham , M E 2017 , ' Rescue of mutant rhodopsin traffic by metformin-induced AMPK activation accelerates photoreceptor ....

مصطلحات موضوعية: AMP-Activated Protein Kinases/biosynthesis, Animals, Disease Models, Animal, Humans, Metformin/administration & dosage, Mice, Mutant Proteins/genetics, Photoreceptor Cells/drug effects, Protein Folding/drug effects, Proteostasis Deficiencies/genetics, Rats, Retinal Degeneration/drug therapy, Retinal Rod Photoreceptor Cells/drug effects, Retinitis Pigmentosa/drug therapy, Rhodopsin/chemistry, Rod Cell Outer Segment/drug effects, Transcriptional Activation/drug effects

الاتاحة: https://research.manchester.ac.uk/en/publications/218031a6-b879-4f29-a8c6-81badd63c376
https://doi.org/10.1093/hmg/ddw387

المؤلفون: Frandsen, Stine Krog, Gehl, Julie

المصدر: Frandsen , S K & Gehl , J 2017 , ' Effect of calcium electroporation in combination with metformin in vivo and correlation between viability and intracellular ATP level after calcium electroporation in vitro ' , PLOS ONE , vol. 12 , no. 7 , e0181839 . https://doi.org/10.1371/journal.pone.0181839

مصطلحات موضوعية: Adenosine Triphosphate/analysis, Animals, Antineoplastic Agents/administration & dosage, Calcium/administration & dosage, Cell Line, Tumor, Cell Survival, Electrochemotherapy/methods, Female, HT29 Cells, Humans, In Vitro Techniques, Male, Metformin/administration & dosage, Mice, Neoplasms, Experimental/drug therapy

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/effect-of-calcium-electroporation-in-combination-with-metformin-in-vivo-and-correlation-between-viability-and-intracellular-atp-level-after-calcium-electroporation-in-vitro(dce6c2ca-ea31-4865-aa65-c8e43229a0ab).html
https://doi.org/10.1371/journal.pone.0181839
https://curis.ku.dk/ws/files/195961719/journal.pone.0181839.pdf

المؤلفون: Petrie, John R, Chaturvedi, Nish, Ford, Ian, Hramiak, Irene, Hughes, Alun D, Jenkins, Alicia J, E Klein, Barbara, Klein, Ron, Ooi, Teik Chye, Rossing, Peter, Sattar, Naveed, Stehouwer, Coen D A, Colhoun, Helen M

المصدر: Petrie , J R , Chaturvedi , N , Ford , I , Hramiak , I , Hughes , A D , Jenkins , A J , E Klein , B , Klein , R , Ooi , T C , Rossing , P , Sattar , N , Stehouwer , C D A , Colhoun , H M & REMOVAL Trial Team 2017 , ' Metformin in adults with type 1 diabetes : Design and methods of REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL): An international multicentre trial ' , Diabetes, Obesity and Metabolism , vol. 19 , ....

مصطلحات موضوعية: Adult, Atherosclerosis/drug therapy, Blood Glucose/drug effects, Body Weight/drug effects, Carotid Intima-Media Thickness, Cholesterol, LDL/blood, Clinical Protocols, Diabetes Mellitus, Type 1/blood, Disease Progression, Double-Blind Method, Drug Therapy, Combination, Female, Glycated Hemoglobin A/drug effects, Humans, Hypoglycemia/chemically induced, Hypoglycemic Agents/administration & dosage, Insulin/administration & dosage, Male, Metformin/administration & dosage, Middle Aged, Risk Factors, Single-Blind Method

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/metformin-in-adults-with-type-1-diabetes(1161e9b3-7bc1-4dd5-ad1f-1e860840068b).html
https://doi.org/10.1111/dom.12840
https://curis.ku.dk/ws/files/193963659/Petrie_et_al_2017_Diabetes_Obesity_and_Metabolism.pdf

المؤلفون: Nyberg, Gunnar F

المصدر: Medicinsk Access. 12(1):34

المؤلفون: van der Aa, M P, Elst, M A J, van de Garde, E M W, van Mil, E G A H, Knibbe, C A J, van der Vorst, M M J

المصدر: van der Aa , M P , Elst , M A J , van de Garde , E M W , van Mil , E G A H , Knibbe , C A J & van der Vorst , M M J 2016 , ' Long-term treatment with metformin in obese, insulin-resistant adolescents : results of a randomized double-blinded placebo-controlled trial ' , Nutrition & Diabetes , vol. 6 , no. 8 , pp. e228 . https://doi.org/10.1038/nutd.2016.37

مصطلحات موضوعية: Adolescent, Body Composition/drug effects, Child, Double-Blind Method, Exercise, Female, Humans, Hypoglycemic Agents/administration & dosage, Insulin Resistance/physiology, Life Style, Male, Metformin/administration & dosage, Obesity/drug therapy, Treatment Outcome

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/50e4c9c6-8e40-4e2c-b5e6-4c68bb62b703
https://doi.org/10.1038/nutd.2016.37

المؤلفون: Lundby-Christensen, Louise, Vaag, Allan, Tarnow, Lise, Almdal, Thomas P., Lund, Søren S., Wetterslev, Jørn, Gluud, Christian, Boesgaard, Trine W., Wiinberg, Niels, Perrild, Hans, Krarup, Thure, Snorgaard, Ole, Gade-Rasmussen, Birthe, Thorsteinsson, Birger, Røder, Michael, Mathiesen, Elisabeth R., Jensen, Tonny, Vestergaard, Henrik, Hedetoft, Christoffer, Breum, Leif, Duun, Elsebeth, Sneppen, Simone B., Pedersen, Oluf, Hemmingsen, Bianca, Carstensen, Bendix, Madsbad, Sten

المصدر: Lundby-Christensen , L , Vaag , A , Tarnow , L , Almdal , T P , Lund , S S , Wetterslev , J , Gluud , C , Boesgaard , T W , Wiinberg , N , Perrild , H , Krarup , T , Snorgaard , O , Gade-Rasmussen , B , Thorsteinsson , B , Røder , M , Mathiesen , E R , Jensen , T , Vestergaard , H , Hedetoft , C , Breum , L , Duun , E , Sneppen , S B , Pedersen , O , Hemmingsen , ....

مصطلحات موضوعية: Blood Glucose/drug effects, Body Weight/drug effects, Carotid Intima-Media Thickness, Denmark, Diabetes Mellitus, Type 2/drug therapy, Drug Administration Schedule, Female, Glycated Hemoglobin A/drug effects, Humans, Hypoglycemia/drug therapy, Hypoglycemic Agents/administration & dosage, Insulin Aspart/administration & dosage, Insulin Detemir/administration & dosage, Insulin/administration & dosage, Male, Metformin/administration & dosage, Middle Aged, Treatment Outcome

وصف الملف: application/pdf

Relation: https://portal.findresearcher.sdu.dk/da/publications/36a62136-7957-41f0-b5d8-9bac4525ce6d

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/36a62136-7957-41f0-b5d8-9bac4525ce6d
https://doi.org/10.1136/bmjopen-2015-008377
https://findresearcher.sdu.dk/ws/files/204527207/e008377.full_1_.pdf

المؤلفون: Forsen, Kent

المصدر: Svensk Cardiologi. (4):32

المؤلفون: Hexeberg, S, Lindberg, F

المصدر: Tidsskrift for Den Norske Laegeforening. 128(4):443

المساهمون: Kyong-Hwa Jun, Jung Eun Lee, Se Hoon Kim, Ji-Han Jung, Hyun�멙oo Choi, Young Il Kim, Hyung-Min Chin, Seung-Ho Yang, Kim, Se Hoon

مصطلحات موضوعية: Adult, Aged, 80 and over, Animals, Antigens, CD/metabolism, Brain Neoplasms/drug therapy, Brain Neoplasms/metabolism, Brain Neoplasms/pathology, Brain Neoplasms/secondary, Cadherins/metabolism, Case-Control Studies, Cell Line, Tumor, Epithelial-Mesenchymal Transition/drug effects, Female, Gene Expression Regulation, Neoplastic/drug effects, Humans, Male, Metformin/administration & dosage, Metformin/pharmacology, Mice, Middle Aged, Stomach Neoplasms/drug therapy, Stomach Neoplasms/metabolism, Stomach Neoplasms/pathology, Vascular Endothelial Growth Factor A/metabolism, Xenograft Model Antitumor Assays

وصف الملف: 2047~2053

Relation: ONCOLOGY REPORTS; J02419; OAK-2015-01791; https://ir.ymlib.yonsei.ac.kr/handle/22282913/140951; http://www.spandidos-publications.com/or/34/4/2047; T201503089; ONCOLOGY REPORTS, Vol.34(4) : 2047-2053, 2015

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/140951
https://doi.org/10.3892/or.2015.4191
http://www.spandidos-publications.com/or/34/4/2047

المؤلفون: Rabbum, Torkil

المصدر: Diabetesforum. 28(4):26

المساهمون: Donghwan Lee, Hyerang Roh, Hankil Son, Seong Bok Jang, Seoungoh Lee, Su Youn Nam, Kyungsoo Park, Roh, Hye Rang, Park, Kyung Soo, Son, Han kil, Lee, Dong Hwan

مصطلحات موضوعية: Administration, Oral, Adult, Area Under Curve, Asian Continental Ancestry Group, Cross-Over Studies, Drug Interactions, Drug Therapy, Combination/adverse effects, Healthy Volunteers, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage, Hydroxymethylglutaryl-CoA Reductase Inhibitors/adverse effects, Hydroxymethylglutaryl-CoA Reductase Inhibitors/pharmacokinetics, Hypoglycemic Agents/administration & dosage, Hypoglycemic Agents/adverse effects, Hypoglycemic Agents/pharmacokinetics, Male, Metformin/administration & dosage, Metformin/adverse effects, Metformin/pharmacokinetics, Middle Aged, Republic of Korea, Rosuvastatin Calcium/administration & dosage, Rosuvastatin Calcium/adverse effects, Rosuvastatin Calcium/pharmacokinetics, Young Adult, Drug�밺rug interaction, metformin, pharmacokinetics

وصف الملف: 1171~1181

Relation: CLINICAL THERAPEUTICS; J00614; OAK-2014-01725; https://ir.ymlib.yonsei.ac.kr/handle/22282913/99645; http://www.sciencedirect.com/science/article/pii/S0149291814003609; T201402949; CLINICAL THERAPEUTICS, Vol.36(8) : 1171-1181, 2014

الاتاحة: https://ir.ymlib.yonsei.ac.kr/handle/22282913/99645
https://doi.org/10.1016/j.clinthera.2014.06.004
http://www.sciencedirect.com/science/article/pii/S0149291814003609

المؤلفون: van der Aa, Marloes P, Elst, Marieke A J, van Mil, Edgar G A H, Knibbe, Catherijne A J, van der Vorst, Marja M J

المصدر: van der Aa , M P , Elst , M A J , van Mil , E G A H , Knibbe , C A J & van der Vorst , M M J 2014 , ' METFORMIN : an efficacy, safety and pharmacokinetic study on the short-term and long-term use in obese children and adolescents - study protocol of a randomized controlled study ' , Trials , vol. 15 , pp. 207 . https://doi.org/10.1186/1745-6215-15-207

مصطلحات موضوعية: Adolescent, Body Composition/drug effects, Child, Double-Blind Method, Female, Follow-Up Studies, Humans, Hypoglycemic Agents/administration & dosage, Insulin Resistance, Male, Metformin/administration & dosage, Obesity/complications, Physical Fitness, Prediabetic State/drug therapy, Prospective Studies, Research Design, Vascular Stiffness/drug effects

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/e46f6798-9f09-4db8-9c80-3dc97c36a479
https://doi.org/10.1186/1745-6215-15-207

المؤلفون: Cardel, Majken, Jensen, S. M., Pottegård, Anton, Jorgensen, T. L., Hallas, J.

المصدر: Cardel , M , Jensen , S M , Pottegård , A , Jorgensen , T L & Hallas , J 2014 , ' Long-term use of metformin and colorectal cancer risk in type II diabetics : a population-based case-control study ' , Cancer Medicine , vol. 3 , no. 5 , pp. 1458-1466 . https://doi.org/10.1002/cam4.306

مصطلحات موضوعية: Aged, 80 and over, Case-Control Studies, Colorectal Neoplasms/epidemiology, Diabetes Mellitus, Type 2/complications, Female, Humans, Hypoglycemic Agents/administration & dosage, Male, Metformin/administration & dosage, Middle Aged, Odds Ratio, Population Surveillance, Registries

Relation: https://portal.findresearcher.sdu.dk/da/publications/0ed3b9bd-5d2a-4990-81eb-551881e42c1b

الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/0ed3b9bd-5d2a-4990-81eb-551881e42c1b
https://doi.org/10.1002/cam4.306