المؤلفون: Kim, Se-Jin, Ho Hur, Joon, Park, Channy, Kim, Hyung-Jin, Oh, Gi-Su, Lee, Joon No, Yoo, Su-Jin, Choe, Seong-Kyu, So, Hong-Seob, Lim, David J, Moon, Sung K, Park, Raekil

المصدر: Experimental & molecular medicine. 47(2)

مصطلحات موضوعية: Organ of Corti, Cell Line, Intracellular Space, Animals, Mice, Rats, Cisplatin, Nitric Oxide, Reactive Oxygen Species, Cysteine, Superoxide Dismutase, Glutathione, Antioxidants, Apoptosis, Gene Expression Regulation, RNA Interference, Male, Metabolic Detoxication, Phase II, NF-E2-Related Factor 2, Heme Oxygenase-1, Caspase 8, Caspase 3, Gene Knockdown Techniques, Metabolic Detoxication, Phase II, Medicinal and Biomolecular Chemistry, Biochemistry & Molecular Biology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8dn6x51w

المؤلفون: Sagri, Efthimia, Reczko, Martin, Gregoriou, Maria-Eleni, Tsoumani, Konstantina T, Zygouridis, Nikolaos E, Salpea, Klelia D, Zalom, Frank G, Ragoussis, Jiannis, Mathiopoulos, Kostas D

المصدر: BMC genomics. 15(1)

مصطلحات موضوعية: Animals, Tephritidae, Macrolides, Cytochrome P-450 Enzyme System, Receptors, Nicotinic, Protein Subunits, Drug Combinations, Insecticides, Cloning, Molecular, Computational Biology, Immunity, Gene Expression Regulation, Amino Acid Sequence, Energy Metabolism, Drug Resistance, Polymorphism, Single Nucleotide, Quantitative Trait Loci, Molecular Sequence Data, Female, Male, Metabolic Detoxication, Phase I, Gene Regulatory Networks, Stress, Physiological, Molecular Sequence Annotation, Transcriptome, Insecticide tolerance, Spinosyns, Next generation sequencing, Expression analysis, Receptors, Nicotinic, Cloning, Molecular, Polymorphism, Single Nucleotide, Metabolic Detoxication, Phase I, Stress, Physiological, Biological Sciences, Information and Computing Sciences, Medical and Health Sciences, Bioinformatics

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3848d843

المؤلفون: Jiali Liu, Rongrong Gao, Xuejing Gu, Bin Yu, Yan Wu, Qiushi Li, Ping Xiang, Hui Xu

المصدر: Molecules; Volume 27; Issue 6; Pages: 1797

مصطلحات موضوعية: colchicine analogues, gastrointestinal toxicity, intestinal tight junction protein ZO-1, molecular docking, structure–toxicity relationship, metabolic detoxication

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/molecules27061797

الاتاحة: https://doi.org/10.3390/molecules27061797

المؤلفون: Díaz Díaz, David, Recacha, Esther, García-Duque, Ana, Docobo-Pérez, Fernando, Blázquez Gómez, Jesús, Pascual, Álvaro, Rodríguez-Martínez, José-Manuel

المساهمون: Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (España), Comisión Asesora de Investigación Científica y Técnica, CAICYT (España), European Commission

مصطلحات موضوعية: Antibiotic resistance, Bacterial, Ciprofloxacin, Detoxification therapy, Fluoroquinolones, Genes, Metabolic detoxication, Drug, Reactive oxygen species, Sos response (genetics), Antimicrobials, Escherichia coli, Multi-antibiotic resistance, Soft drinks, Prevention

وصف الملف: application/pdf

Relation: Publisher's version; https://doi.org/10.1093/jac/dkab445; Sí; Journal of Antimicrobial Chemotherapy 77(3): 641-645 (2022); http://hdl.handle.net/10261/305646; http://dx.doi.org/10.13039/501100004587; http://dx.doi.org/10.13039/501100007272; http://dx.doi.org/10.13039/501100000780; 2-s2.0-85125211784; https://api.elsevier.com/content/abstract/scopus_id/85125211784

الاتاحة: http://hdl.handle.net/10261/305646
https://doi.org/10.1093/jac/dkab445
https://doi.org/10.13039/501100004587
https://doi.org/10.13039/501100007272
https://doi.org/10.13039/501100000780
https://api.elsevier.com/content/abstract/scopus_id/85125211784

المؤلفون: Ma, Xiaocui, Duan, Yuyou, Tschudy-Seney, Benjamin, Roll, Garrett, Behbahan, Iman Saramipoor, Ahuja, Tijess P, Tolstikov, Vladimir, Wang, Charles, McGee, Jeannine, Khoobyari, Shiva, Nolta, Jan A, Willenbring, Holger, Zern, Mark A

المصدر: Stem Cells Translational Medicine. 2(6)

مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, Stem Cell Research, Regenerative Medicine, Biotechnology, Stem Cell Research - Induced Pluripotent Stem Cell, Digestive Diseases, Liver Disease, Stem Cell Research - Induced Pluripotent Stem Cell - Human, 1.1 Normal biological development and functioning, Oral and gastrointestinal, Generic health relevance, Adrenergic beta-Antagonists, Albumins, Animals, Biomarkers, Cell Differentiation, Cells, Cultured, Chromatography, Liquid, Cytochrome P-450 Enzyme System, Ethanolamines, Gene Expression, Hepatocytes, Humans, Immunocompromised Host, Induced Pluripotent Stem Cells, Liver, Metabolic Detoxication, Phase I, Metabolic Detoxication, Phase II, Mice, Mice, SCID, Receptors, Cytoplasmic and Nuclear, Tandem Mass Spectrometry, Transplantation, Heterologous, Induced pluripotent stem cells, Hepatocyte differentiation, Stem cell transplantation, Liver regeneration, Biochemistry and Cell Biology, Clinical Sciences, Medical biotechnology, Biomedical engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/8bn1t3hb
https://escholarship.org/content/qt8bn1t3hb/qt8bn1t3hb.pdf

المؤلفون: Lavado, Ramon, Aparicio-Fabre, Rosaura, Schlenk, Daniel

المصدر: Fish Physiology and Biochemistry. 40(1)

مصطلحات موضوعية: Agricultural, Veterinary and Food Sciences, Fisheries Sciences, Digestive Diseases, Liver Disease, Acclimatization, Animals, Biometry, Cytochrome P-450 Enzyme System, Immunoblotting, Metabolic Detoxication, Phase I, Oncorhynchus kisutch, Oxygenases, Salinity, Salmonids, Salinity acclimation, Pesticide biotransformation, CYP450, FMO, Ecology, Fisheries, Fisheries sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/1pf3d72z

المؤلفون: Morrissey, Kari M, Stocker, Sophie L, Wittwer, Matthias B, Xu, Lu, Giacomini, Kathleen M

المصدر: Annual review of pharmacology and toxicology. 53(1)

مصطلحات موضوعية: Kidney Tubules, Animals, Humans, Pharmaceutical Preparations, Xenobiotics, Biological Transport, Pharmacokinetics, Inactivation, Metabolic, renal clearance, SLC transporters, ABC transporters, drug metabolism, nephrotoxicity, pharmacokinetics, Inactivation, Metabolic, Metabolic Detoxication, Drug, Pharmacology & Pharmacy, Medical and Health Sciences, Biological Sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/189450bf

المؤلفون: Masson, Carmen L, Barnett, Paul G, Sees, Karen L, Delucchi, Kevin L, Rosen, Amy, Wong, Wynnie, Hall, Sharon M

المصدر: Addiction (Abingdon, England). 99(6)

مصطلحات موضوعية: Adult, Cost-Benefit Analysis, Female, Humans, Male, Metabolic Detoxication, Drug, Methadone, Narcotics, Opioid-Related Disorders, Treatment Outcome

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2p97h3rx

المؤلفون: Canet, Luz M, Sánchez-Maldonado, Jose M, Cáliz, Rafael, Rodríguez-Ramos, Ana, Lupiañez, Carmen B, Canhão, Helena, Martínez-Bueno, Manuel, Escudero, Alejandro, Segura-Catena, Juana, Sorensen, Signe B, Hetland, Merete L, Soto-Pino, María José, Ferrer, Miguel A, García, Antonio, Glintborg, Bente, Filipescu, Ileana, Pérez-Pampin, Eva, González-Utrilla, Alfonso, Nevot, Miguel Ángel López, Conesa-Zamora, Pablo, Broeder, Alfons den, De Vita, Salvatore, Jacobsen, Sven Erik Hobe, Collantes-Estevez, Eduardo, Quartuccio, Luca, Canzian, Federico, Fonseca, João E, Coenen, Marieke J H, Andersen, Vibeke, Sainz, Juan

المصدر: Canet , L M , Sánchez-Maldonado , J M , Cáliz , R , Rodríguez-Ramos , A , Lupiañez , C B , Canhão , H , Martínez-Bueno , M , Escudero , A , Segura-Catena , J , Sorensen , S B , Hetland , M L , Soto-Pino , M J , Ferrer , M A , García , A , Glintborg , B , Filipescu , I , Pérez-Pampin , E , González-Utrilla , A , Nevot , M Á L , Conesa-Zamora , P , Broeder , A D , De Vita , S , ....

مصطلحات موضوعية: Antirheumatic Agents/therapeutic use, Arthritis, Rheumatoid/drug therapy, Case-Control Studies, Cytochrome P-450 CYP2C9/genetics, Cytochrome P-450 CYP3A/genetics, Estrogen Receptor beta/genetics, Female, Gonadal Steroid Hormones/genetics, Haplotypes/genetics, Humans, Male, Metabolic Detoxication, Phase I/genetics, Polymorphism, Single Nucleotide/genetics, Tumor Necrosis Factor-alpha/antagonists & inhibitors, Ubiquitin-Protein Ligases/genetics

وصف الملف: application/pdf

الاتاحة: https://researchprofiles.ku.dk/da/publications/polymorphisms-at-phase-imetabolizing-enzyme-and-hormone-receptor-loci-influence-the-response-to-antitnf-therapy-in-rheumatoid-arthritis-patients(afccbe1e-8204-49e7-87d5-660523d4eb03).html
https://doi.org/10.1038/s41397-018-0057-x
https://curis.ku.dk/ws/files/255840061/Polymorphisms_at_phase_I_metabolizing_enzyme_and_hormone_receptor_loci_influence_the_response_to_anti_TNF_therapy_in_rheumatoid_arthritis_patients.pdf

المساهمون: Deng, Y, Wang, Yaling, Sun, L, Lu, P, Wang, R, Ye, L, Xu, D, Ye, Riying, Liu, Y, Bi, S, Gooneratne, SR

وصف الملف: pp.113-122; Print-Electronic

Relation: The original publication is available from Taylor & Francis Group - https://doi.org/10.1080/01480545.2017.1320407 - http://dx.doi.org/10.1080/01480545.2017.1320407; Drug and Chemical Toxicology

الاتاحة: http://api.digitalnz.org/records/56053030/source

المؤلفون: Peile Wang, Xin-Sheng Yao, Frank J. Gonzalez, Han Xing, Zhihong Yao, Kaidi Ren, Xiaojian Zhang, Zifei Qin, Jing Yang

المصدر: J Pharm Pharmacol

مصطلحات موضوعية: Male, CYP2B6, Psoralea corylifolia, Glucuronidation, Pharmaceutical Science, Pharmacology, digestive system, 030226 pharmacology & pharmacy, Article, Psoralea, Mice, 03 medical and health sciences, Glucuronides, 0302 clinical medicine, Species Specificity, In vivo, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Enzyme Inhibitors, Glucuronosyltransferase, Flavonoids, biology, Plant Extracts, Chemistry, CYP1A2, Metabolism, biology.organism_classification, Metabolic Detoxication, Phase II, Isoenzymes, Kinetics, 030220 oncology & carcinogenesis, Microsomes, Liver, Microsome, Metabolic Detoxication, Phase I, Oxidation-Reduction, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981dc42dda19e239283f5bd5f3f6b438
https://doi.org/10.1111/jphp.13337

المؤلفون: Xin-Sheng Yao, Shishi Li, Zifei Qin, Jinjin Xu, Liufang Hu, Yang Li, Frank J. Gonzalez, Chunxia Xu, Zhihong Yao

المصدر: J Pharm Pharmacol

مصطلحات موضوعية: Swine, Flavonoid, Glucuronidation, Pharmaceutical Science, Pharmacology, Isozyme, Article, Substrate Specificity, Mice, 03 medical and health sciences, Dogs, Glucuronides, 0302 clinical medicine, Cytochrome P-450 Enzyme System, ATP Binding Cassette Transporter, Subfamily G, Member 2, Animals, Humans, Glucuronosyltransferase, CYP2C9, 030304 developmental biology, Flavonoids, chemistry.chemical_classification, 0303 health sciences, Biological Transport, Haplorhini, Metabolism, Metabolic Detoxication, Phase II, Neoplasm Proteins, Rats, Isoenzymes, Kinetics, chemistry, 030220 oncology & carcinogenesis, Microsomes, Liver, Microsome, Swine, Miniature, Metabolic Detoxication, Phase I, Rabbits, Multidrug Resistance-Associated Proteins, Glucuronide, Drug metabolism, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d91446ed5c4eae1ed3305f638b813a0
https://doi.org/10.1111/jphp.13324

المؤلفون: Shane K. Eagles, Andrew J. McLachlan, Annette S. Gross

المصدر: Clinical Pharmacology & Therapeutics. 108:212-227

مصطلحات موضوعية: Drug, media_common.quotation_subject, Physiology, Context (language use), Risk Assessment, Substrate Specificity, Food-Drug Interactions, Pharmacotherapy, Cytochrome P-450 CYP1A2, Risk Factors, Vegetables, Humans, Medicine, Ingestion, Pharmacology (medical), Clinical significance, Glutathione Transferase, media_common, Pharmacology, Clinical Trials as Topic, business.industry, Cruciferous vegetables, Metabolic Detoxication, Phase II, Diet, Isoenzymes, Pharmaceutical Preparations, Meta-analysis, Brassicaceae, Metabolic Detoxication, Phase I, business, Nutritive Value, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b914e383adfaab5dfa8d1eba32fafe70
https://doi.org/10.1002/cpt.1811

المؤلفون: Ostergaard, Mathias, Jatzkowski, Leonie, Seitz, Raffaela, Speidel, Samantha, Weber, Tanja, Lübke, Norbert, Höcker, Wolfgang, Odenwald, Michael

المصدر: Alcohol and Alcoholism. 2018, 53(6), pp. 719-727. ISSN 0735-0414. eISSN 1464-3502. Available under: doi:10.1093/alcalc/agy066

مصطلحات موضوعية: ethanol, detoxification therapy, comorbidity, depressive disorders, diagnosis dual (psychiatry), inpatients, mental disorders, metabolic detoxication drug, motivation, patient readmission, post-traumatic stress disorder, wounds and injuries, integrated treatment, ddc:150

وصف الملف: application/pdf

Relation: http://nbn-resolving.de/urn:nbn:de:bsz:352-2-kyzpqhx8n8gx8; http://dx.doi.org/10.1093/alcalc/agy066; 513722424

الاتاحة: http://nbn-resolving.de/urn:nbn:de:bsz:352-2-kyzpqhx8n8gx8
https://doi.org/10.1093/alcalc/agy066

المؤلفون: Alfonso Narváez, Yelko Rodríguez-Carrasco, Alberto Ritieni, Giulia Graziani, Luana Izzo, Anna Gaspari

المساهمون: Rodriguez-Carrasco, Y., Narvaez, A., Izzo, L., Gaspari, A., Graziani, G., Ritieni, A.

المصدر: Toxins
Toxins, Vol 12, Iss 415, p 415 (2020)
Volume 12
Issue 6

مصطلحات موضوعية: Fusarium, Adult, Male, Spectrometry, Mass, Electrospray Ionization, high resolution mass spectrometry (HRMS), Health, Toxicology and Mutagenesis, Population, lcsh:Medicine, Urine, Urinalysis, Toxicology, 01 natural sciences, Article, chemistry.chemical_compound, 0404 agricultural biotechnology, Metabolomics, Limit of Detection, Tandem Mass Spectrometry, High resolutionmass spectrometry (HRMS), Depsipeptides, Biomonitoring, Humans, education, Mycotoxin, Chromatography, High Pressure Liquid, Enniatin B1, education.field_of_study, Chromatography, biology, Chemistry, 010401 analytical chemistry, lcsh:R, In vivo analysis, 04 agricultural and veterinary sciences, Middle Aged, biology.organism_classification, 040401 food science, metabolomics, 0104 chemical sciences, in vivo, biomonitoring, Female, Metabolic Detoxication, Phase I, Enniatin, Biomarkers, Biological Monitoring

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8497ca7ea78e4286fa2f0180aeb64829
https://doi.org/10.9734/bpi/mono/978-93-5547-768-2/ch8

المؤلفون: Jeffrey P. Jones, John T. Rodgers

المصدر: Drug Metab Dispos

مصطلحات موضوعية: Time Factors, N-Methyl-3,4-methylenedioxyamphetamine, Pharmaceutical Science, Numerical modeling, In Vitro Techniques, Kinetic inhibition, Models, Biological, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Cytochrome P-450 CYP2D6 Inhibitors, medicine, Humans, Computer Simulation, Reversible inhibition, Liver microsomes, Pharmacology, Human liver, Chemistry, MDMA, Articles, Metabolic Detoxication, Phase II, Cytochrome P-450 CYP2D6, 030220 oncology & carcinogenesis, Microsomes, Liver, Biophysics, Metabolic Detoxication, Phase I, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ee8c85e6d97d59b7b804a31027b66b
https://doi.org/10.1124/dmd.119.089268

المؤلفون: S Q Jiang, W Chen, Yongwen Zhu, D Ruan, S J Yan, W G Xia, C T Zheng, Lin Yang, Y N Zhang, A.M. Fouad, S Wang

المصدر: Poultry Science. 98:3705-3714

مصطلحات موضوعية: Male, Curcumin, Antioxidant, medicine.medical_treatment, Gene Expression, Detoxification enzymes, Antioxidants, Random Allocation, 03 medical and health sciences, chemistry.chemical_compound, Basal (phylogenetics), Gene expression, medicine, Animals, Food science, Tissue distribution, 030304 developmental biology, 0303 health sciences, biology, 0402 animal and dairy science, Cytochrome P450, 04 agricultural and veterinary sciences, General Medicine, Animal Feed, 040201 dairy & animal science, Metabolic Detoxication, Phase II, Diet, Intestines, Antioxidant capacity, Ducks, chemistry, Dietary Supplements, biology.protein, Metabolic Detoxication, Phase I, Animal Science and Zoology, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4afb3e6e35a3464c4250b16316233649
https://doi.org/10.3382/ps/pez058

المؤلفون: Sowada, Juliane, Lemoine, Lisa, Schön, Karsten, Hutzler, Christoph, Luch, Andreas, Tralau, Tewes

مصطلحات موضوعية: Benzo[a]pyrene, Cytotoxicity, Genotoxicity, Microbiome, PAHs, Polycyclic aromatic hydrocarbons, Toxification, Bacillus licheniformis, Cell Line, Cell Survival, Comet Assay, DNA Damage, Gas Chromatography-Mass Spectrometry, Humans, Keratinocytes, Metabolic Detoxication, Phase I, Microbiota, Micrococcus luteus, Skin

وصف الملف: Print-Electronic; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/301653

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/301653
https://doi.org/10.17863/CAM.48724

المؤلفون: Zifei Qin, Liufang Hu, Xin-Sheng Yao, Yi Dai, Xiaojun Song, Zhihong Yao, Haruki Yamada, Hiroaki Kiyohara, Liyin Liu

المصدر: Journal of Pharmaceutical and Biomedical Analysis. 171:81-98

مصطلحات موضوعية: Male, Clinical Biochemistry, Glucuronidation, Administration, Oral, Pharmaceutical Science, Traditional Chinese medicine, Tandem mass spectrometry, 01 natural sciences, Analytical Chemistry, Rats, Sprague-Dawley, Feces, Lactones, Sulfation, Pharmacokinetics, Tandem Mass Spectrometry, In vivo, Drug Discovery, Animals, Radix, Chromatography, High Pressure Liquid, Spectroscopy, Flavonoids, Chromatography, Molecular Structure, 010405 organic chemistry, Chemistry, 010401 analytical chemistry, Metabolic Detoxication, Phase II, Triterpenes, 0104 chemical sciences, Metabolic pathway, Metabolome, Metabolic Detoxication, Phase I, Sesquiterpenes, Drugs, Chinese Herbal

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f5844007d28c6d5d4e8a66c231f35f
https://doi.org/10.1016/j.jpba.2019.04.001

المؤلفون: Marc Elskens, Adrian Covaci, Philippe Vervliet, Kirsten Van Landuyt, Jens Van Den Plas, Imke Boonen, Siemon De Nys, Radu Corneliu Duca

المساهمون: Faculty of Sciences and Bioengineering Sciences, Chemistry, Analytical, Environmental & Geo-Chemistry, Biology

المصدر: Toxicology

مصطلحات موضوعية: Male, 0301 basic medicine, Spectrometry, Mass, Electrospray Ionization, Dental resins, Polyurethanes, Glucuronates, Cytosolic fractions, Hydroxylation, Toxicology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Biotransformation, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Human liver microsomes, Humans, Bisphenol A-Glycidyl Methacrylate, Liquid chromatography-mass spectrometry, Acrylic acid, Chromatography, Sulfates, Pharmacology. Therapy, Glucuronic acid, UDMA, Metabolic Detoxication, Phase II, 030104 developmental biology, chemistry, Dealkylation, Microsomes, Liver, Microsome, In vitro biotransformation, Methacrylates, Female, Metabolic Detoxication, Phase I, Oxidation-Reduction, 030217 neurology & neurosurgery, Drug metabolism, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8649afeaf42f35430fa884c3747857
https://doi.org/10.1016/j.tox.2019.03.007