المؤلفون: Vázquez Torres, Susana, Benard Valle, Melisa, Mackessy, Stephen P., Menzies, Stefanie K., Casewell, Nicholas R., Ahmadi, Shirin, Burlet, Nick J., Muratspahić, Edin, Sappington, Isaac, Overath, Max D., Rivera-de-Torre, Esperanza, Ledergerber, Jann, Laustsen, Andreas H., Boddum, Kim, Bera, Asim K., Kang, Alex, Brackenbrough, Evans, Cardoso, Iara A., Crittenden, Edouard P., Edge, Rebecca J., Decarreau, Justin, Ragotte, Robert J., Pillai, Arvind S., Abedi, Mohamad, Han, Hannah L., Gerben, Stacey R., Murray, Analisa, Skotheim, Rebecca, Stuart, Lynda, Stewart, Lance, Fryer, Thomas J. A., Jenkins, Timothy P., Baker, David

المصدر: Nature ; ISSN 0028-0836 1476-4687

الاتاحة: https://doi.org/10.1038/s41586-024-08393-x
https://www.nature.com/articles/s41586-024-08393-x.pdf
https://www.nature.com/articles/s41586-024-08393-x

المؤلفون: Solano, Gabriela, Cunningham, Sinead, Edge, Rebecca J., Duran, Gina, Sanchez, Adriana, Villalta, Mauren, Clare, Rachel H., Wilkinson, Mark C., Marriott, Amy E., Abada, Camille, Menzies, Stefanie K., Keen, Molly, Lalloo, David G., Stienstra, Ymkje, Abouyannis, Michael, Casewell, Nicholas R., León, Guillermo, Ainsworth, Stuart

المصدر: Solano , G , Cunningham , S , Edge , R J , Duran , G , Sanchez , A , Villalta , M , Clare , R H , Wilkinson , M C , Marriott , A E , Abada , C , Menzies , S K , Keen , M , Lalloo , D G , Stienstra , Y , Abouyannis , M , Casewell , N R , León , G & Ainsworth , S 2024 , ' African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry : ....

مصطلحات موضوعية: Snake bite, stings and other envenoming

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/e18cf99d-5c4e-4945-8659-8bfaf4641b8f
https://research.rug.nl/en/publications/e18cf99d-5c4e-4945-8659-8bfaf4641b8f
https://doi.org/10.1136/bmjgh-2023-014813
https://pure.rug.nl/ws/files/963018804/e014813.full.pdf
http://www.scopus.com/inward/record.url?scp=85188010483&partnerID=8YFLogxK

المؤلفون: Edge, Rebecca J., Marriott, Amy E., Keen, Molly, Xie, Tiffany, Crittenden, Edouard, Dawson, Charlotte A., Wilkinson, Mark C., Wüster, Wolfgang, Casewell, Nicholas R., Ainsworth, Stuart, Menzies, Stefanie K.

المصدر: Edge , R J , Marriott , A E , Keen , M , Xie , T , Crittenden , E , Dawson , C A , Wilkinson , M C , Wüster , W , Casewell , N R , Ainsworth , S & Menzies , S K 2024 ' Preclinical Evaluation of the Neutralising Efficacy of Three Monospecific Antivenoms Against the Venoms of Five African Echis Species, Including the Recently Partitioned E. ocellatus and E. romani ' pp. 1 . https://doi.org/10.2139/ssrn.4763108

مصطلحات موضوعية: Snakebite envenoming, Antivenom, Echis, Venom, Preclinical

وصف الملف: application/pdf

الاتاحة: https://research.bangor.ac.uk/portal/en/researchoutputs/preclinical-evaluation-of-the-neutralising-efficacy-of-three-monospecific-antivenoms-against-the-venoms-of-five-african-echis-species-including-the-recently-partitioned-e-ocellatus-and-e-romani(b1c53f6e-a2a9-43e1-a3b0-2f3c7293e9e6).html
https://doi.org/10.2139/ssrn.4763108
https://research.bangor.ac.uk/ws/files/71608214/SSRN-id4763108.pdf

المؤلفون: Menzies, Stefanie K., Arinto-Garcia, Raquel, Gobbi Amorim, Fernanda, Cardoso, Iara Aimê, Abada, Camille, Crasset, Thomas, Durbesson, Fabien, Edge, Rebecca J., El-Kazzi, Priscila, Hall, Sophie, Redureau, Damien, Stenner, Richard, Boldrini-França, Johara, Sun, Huan, Roldão, António, Alves, Paula M., Harrison, Robert A., Vincentelli, Renaud, Berger, Imre, Quinton, Loïc, Casewell, Nicholas R., Schaffitzel, Christiane

المصدر: Toxins, 15 (12), 673 (2023-11-28)

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Toxicology, Life sciences, Biochemistry, biophysics & molecular biology, Sciences du vivant, Biochimie, biophysique & biologie moléculaire

Relation: info:eu-repo/grantAgreement/EC/H2020/899670; https://www.mdpi.com/2072-6651/15/12/673/pdf; urn:issn:2072-6651

URL الوصول: https://orbi.uliege.be/handle/2268/311532

المؤلفون: Gobbi Amorim, Fernanda, Redureau, Damien, Crasset, Thomas, Freuville, Lou, Baiwir, Dominique, Mazzucchelli, Gabriel, Menzies, Stefanie K., Casewell, Nicholas R., Quinton, Loïc

المصدر: Toxins, 15 (6), 357 (2023-05-25)

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, Toxicology, Physical, chemical, mathematical & earth Sciences, Chemistry, Physique, chimie, mathématiques & sciences de la terre, Chimie

Relation: https://www.mdpi.com/2072-6651/15/6/357/pdf; urn:issn:2072-6651

URL الوصول: https://orbi.uliege.be/handle/2268/304320

المؤلفون: Menzies, Stefanie K, Arinto-Garcia, Raquel, Amorim, Fernanda Gobbi, Cardoso, Iara Aimê, Abada, Camille, Crasset, Thomas, Durbesson, Fabien, Edge, Rebecca J, El-Kazzi, Priscila, Hall, Sophie, Redureau, Damien, Stenner, Richard, Boldrini-França, Johara, Sun, Huan, Roldão, António, Alves, Paula M, Harrison, Robert A, Vincentelli, Renaud, Berger, Imre, Quinton, Loïc, Casewell, Nicholas R, Schaffitzel, Christiane

المصدر: Menzies , S K , Arinto-Garcia , R , Amorim , F G , Cardoso , I A , Abada , C , Crasset , T , Durbesson , F , Edge , R J , El-Kazzi , P , Hall , S , Redureau , D , Stenner , R , Boldrini-França , J , Sun , H , Roldão , A , Alves , P M , Harrison , R A , Vincentelli , R , Berger , I , Quinton , L , Casewell , N R & Schaffitzel , C 2023 , ' ADDovenom : ....

مصطلحات موضوعية: /dk/atira/pure/core/keywords/biodesign_SRI, name=Bristol BioDesign Institute, /dk/atira/pure/core/keywords/max_planck_bristol_, name=Max Planck Bristol, Animals, Humans, Snake Bites/drug therapy, Antivenins, Toxins, Biological, Binding Sites, Plasma

Relation: https://research-information.bris.ac.uk/en/publications/76a59023-2d16-46c8-9fd6-b77b4e41a7ca

الاتاحة: https://hdl.handle.net/1983/76a59023-2d16-46c8-9fd6-b77b4e41a7ca
https://research-information.bris.ac.uk/en/publications/76a59023-2d16-46c8-9fd6-b77b4e41a7ca
https://doi.org/10.3390/toxins15120673

المؤلفون: Solano, Gabriela, Cunningham, Sinead, Edge, Rebecca J., Duran, Gina, Sanchez, Adriana, Villalta, Mauren, Clare, Rachel H., Wilkinson, Mark C., Marriott, Amy E., Abada, Camille, Menzies, Stefanie K., Keen, Molly, Lalloo, David G., Stienstra, Ymkje, Abouyannis, Michael, Casewell, Nicholas R., León, Guillermo, Ainsworth, Stuart

مصطلحات الفهرس: Journal Article, PeerReviewed

URL: https://eprints.lancs.ac.uk/id/eprint/219871/
https://eprints.lancs.ac.uk/id/eprint/219871

المؤلفون: Menzies, Stefanie K., Clare, Rachel H., Xie, Chunfang, Westhorpe, Adam, Hall, Steven R., Edge, Rebecca J., Alsolaiss, Jaffer, Crittenden, Edouard, Marriott, Amy E., Harrison, Robert A., Kool, Jeroen, Casewell, Nicholas R.

المصدر: Menzies , S K , Clare , R H , Xie , C , Westhorpe , A , Hall , S R , Edge , R J , Alsolaiss , J , Crittenden , E , Marriott , A E , Harrison , R A , Kool , J & Casewell , N R 2022 , ' In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus ' , Toxicon: X , vol. 14 , 100118 , pp. 1-10 . https://doi.org/10.1016/j.toxcx.2022.100118

مصطلحات موضوعية: Boomslang, Drugs, Small molecules, Snakebite, SVMP

الاتاحة: https://research.vu.nl/en/publications/b34fa0aa-98b1-415c-a1a3-aed9373c9727
https://doi.org/10.1016/j.toxcx.2022.100118
https://hdl.handle.net/1871.1/b34fa0aa-98b1-415c-a1a3-aed9373c9727
http://www.scopus.com/inward/record.url?scp=85126634399&partnerID=8YFLogxK
http://www.scopus.com/inward/citedby.url?scp=85126634399&partnerID=8YFLogxK

المؤلفون: Menzies, Stefanie K., Dawson, Charlotte A., Crittenden, Edouard, Edge, Rebecca J., Hall, Steven R., Alsolaiss, Jaffer, Wilkinson, Mark C., Casewell, Nicholas R., Harrison, Robert A., Ainsworth, Stuart

المساهمون: Department for International Development, UK Government, Medical Research Council, Horizon 2020, UK Research and Innovation, Wellcome Trust

المصدر: Scientific Reports ; volume 12, issue 1 ; ISSN 2045-2322

الاتاحة: http://dx.doi.org/10.1038/s41598-022-13376-x
https://www.nature.com/articles/s41598-022-13376-x.pdf
https://www.nature.com/articles/s41598-022-13376-x

المؤلفون: Menzies, Stefanie K., Litschka-Koen, Thea, Edge, Rebecca J., Alsolaiss, Jaffer, Crittenden, Edouard, Hall, Steven R., Westhorpe, Adam, Thomas, Brent, Murray, James, Shongwe, Nondusimo, Padidar, Sara, Lalloo, David G., Casewell, Nicholas R., Pons, Jonathan, Harrison, Robert A.

المساهمون: Maduwage, Kalana Prasad, Wellcome Trust, Royal Society

المصدر: PLOS Neglected Tropical Diseases ; volume 16, issue 9, page e0010496 ; ISSN 1935-2735

الاتاحة: http://dx.doi.org/10.1371/journal.pntd.0010496
https://dx.plos.org/10.1371/journal.pntd.0010496

المؤلفون: Khalek, Irene S., Laxme, R. R.Senji, Nguyen, Yen Thi Kim, Khochare, Suyog, Patel, Rohit N., Woehl, Jordan, Smith, Jessica M., Saye-Francisco, Karen, Kim, Yoojin, Mindrebo, Laetitia Misson, Tran, Quoc, Kędzior, Mateusz, Boré, Evy, Limbo, Oliver, Verma, Megan, Stanfield, Robyn L., Menzies, Stefanie K., Ainsworth, Stuart, Harrison, Robert A., Burton, Dennis R., Sok, Devin, Wilson, Ian A., Casewell, Nicholas R., Sunagar, Kartik, Jardine, Joseph G.

Relation: Khalek, Irene S. and Laxme, R. R.Senji and Nguyen, Yen Thi Kim and Khochare, Suyog and Patel, Rohit N. and Woehl, Jordan and Smith, Jessica M. and Saye-Francisco, Karen and Kim, Yoojin and Mindrebo, Laetitia Misson and Tran, Quoc and Kędzior, Mateusz and Boré, Evy and Limbo, Oliver and Verma, Megan and Stanfield, Robyn L. and Menzies, Stefanie K. and Ainsworth, Stuart and Harrison, Robert A. and Burton, Dennis R. and Sok, Devin and Wilson, Ian A. and Casewell, Nicholas R. and Sunagar, Kartik and Jardine, Joseph G. (2024) Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins. Science Translational Medicine, 16 (735): eadk1867. ISSN 1946-6234

الاتاحة: https://eprints.lancs.ac.uk/id/eprint/219868/

المؤلفون: Menzies, Stefanie K., Thomas, Aniekan O., Tianyi, Frank-Leonel, Abubakar, Saidu B., Nasidi, Abdulsalami, Durfa, Nandul, Patel, Rohit, Trelfa, Anna, Lalloo, David G., Habib, Abdulrazaq G., Harrison, Robert A.

المساهمون: Chippaux, Jean-Philippe

المصدر: PLOS Neglected Tropical Diseases ; volume 15, issue 8, page e0009518 ; ISSN 1935-2735

الاتاحة: http://dx.doi.org/10.1371/journal.pntd.0009518
https://dx.plos.org/10.1371/journal.pntd.0009518

المؤلفون: Ainsworth, Stuart, Menzies, Stefanie K., Casewell, Nicholas R., Harrison, Robert A.

المساهمون: Calvete, Juan J.

المصدر: PLOS Neglected Tropical Diseases ; volume 14, issue 8, page e0008579 ; ISSN 1935-2735

الاتاحة: http://dx.doi.org/10.1371/journal.pntd.0008579
https://dx.plos.org/10.1371/journal.pntd.0008579

المؤلفون: Amorim, Fernanda Gobbi, Redureau, Damien, Crasset, Thomas, Freuville, Lou, Baiwir, Dominique, Mazzucchelli, Gabriel, Menzies, Stefanie K., Casewell, Nicholas R., Quinton, Loïc

مصطلحات الفهرس: Journal Article, PeerReviewed

URL: https://eprints.lancs.ac.uk/id/eprint/219869/
https://eprints.lancs.ac.uk/id/eprint/219869

المؤلفون: Zacharova, Marija K., Tulloch, Lindsay B., Gould, Eoin R., Fraser, Andrew L., King, Elizabeth F., Menzies, Stefanie K., Smith, Terry K., Florence, Gordon J.

المصدر: Zacharova , M K , Tulloch , L B , Gould , E R , Fraser , A L , King , E F , Menzies , S K , Smith , T K & Florence , G J 2019 , ' Structure‐based design, synthesis and biological evaluation of bis‐tetrahydropyran furan acetogenin mimics targeting the trypanosomatid F1 component of ATP synthase ' , European Journal of Organic Chemistry , vol. 2019 , no. 31-32 , pp. 5434-5440 . https://doi.org/10.1002/ejoc.201900541

مصطلحات موضوعية: Biological activity, Drug design, FoF1-ATP synthase, Homogeneous catalysis, Trypanosomatid, /dk/atira/pure/subjectarea/asjc/1600/1606, name=Physical and Theoretical Chemistry, /dk/atira/pure/subjectarea/asjc/1600/1605, name=Organic Chemistry

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/777c3053-aa2f-4aa1-8fdd-1301e4705713

الاتاحة: https://discovery.dundee.ac.uk/en/publications/777c3053-aa2f-4aa1-8fdd-1301e4705713
https://doi.org/10.1002/ejoc.201900541
https://discovery.dundee.ac.uk/ws/files/35607908/Zacharova_et_al_2019_European_Journal_of_Organic_Chemistry.pdf
http://www.scopus.com/inward/record.url?scp=85066630767&partnerID=8YFLogxK

المؤلفون: Fraser, Andrew L., Menzies, Stefanie K., King, Elizabeth F. B., Tulloch, Lindsay, Gould, Eoin R., Zacharova, Marija, Smith, Terry K., Florence, Gordon J.

المصدر: Fraser , A L , Menzies , S K , King , E F B , Tulloch , L , Gould , E R , Zacharova , M , Smith , T K & Florence , G J 2018 , ' Design and synthesis of broad spectrum trypanosomatid selective inhibitors ' , ACS Infectious Diseases , vol. 4 , no. 4 , pp. 560-567 . https://doi.org/10.1021/acsinfecdis.7b00187

مصطلحات موضوعية: Trypanosomatid, Natural Products, Drug Design, Chemical Tools, Photo-affinity

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/design-and-synthesis-of-broad-spectrum-trypanosomatid-selective-inhibitors(91d55cba-4bf2-44ac-9d02-aeb5dd7d5e4d).html
https://doi.org/10.1021/acsinfecdis.7b00187
https://research-repository.st-andrews.ac.uk/bitstream/10023/16803/1/ID_2017_001875_revised.pdf

المؤلفون: Tulloch, Lindsay B., Menzies, Stefanie K., Coron, Ross P., Roberts, Matthew D., Florence, Gordon J., Smith, Terry K.

المصدر: Tulloch , L B , Menzies , S K , Coron , R P , Roberts , M D , Florence , G J & Smith , T K 2018 , ' Direct and indirect approaches to identify drug modes of action ' , IUBMB Life , vol. 70 , no. 1 , pp. 9-22 . https://doi.org/10.1002/iub.1697

مصطلحات موضوعية: Drug mode of action, Target ID, Genomics, Transcriptomics, Proteomics, Metabolomics, Affinity chromatography, Photo-affinity labelling

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/direct-and-indirect-approaches-to-identify-drug-modes-of-action(bf16bbe6-c295-406f-a178-f6ac36c78ce3).html
https://doi.org/10.1002/iub.1697
https://research-repository.st-andrews.ac.uk/bitstream/10023/16633/1/Direct_and_indirect_approaches_to_identify_drug_modes_of_action_IUBMB_Life_author_accepted_version.pdf

المؤلفون: Menzies, Stefanie K., Tulloch, Lindsay B., Florence, Gordon J., Smith, Terry K.

المصدر: Menzies , S K , Tulloch , L B , Florence , G J & Smith , T K 2018 , ' The trypanosome alternative oxidase : a potential drug target? ' , Parasitology , vol. 145 , no. 2 , pp. 175-183 . https://doi.org/10.1017/S0031182016002109

مصطلحات موضوعية: Trypanosoma alternative oxidase, Drug discovery, Chemotherapy, Human African trypanosomiasis, Sleeping sickness, Trypanosoma brucei

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/the-trypanosome-alternative-oxidase(d385edaa-b1ae-40bb-8351-893c8752e709).html
https://doi.org/10.1017/S0031182016002109
https://research-repository.st-andrews.ac.uk/bitstream/10023/10874/1/Smith_2016_Parasitology_Trypanosome_AAM.pdf

المؤلفون: Tulloch, Lindsay B., Menzies, Stefanie K., Fraser, Andrew L., Gould, Eoin R., King, Elizabeth F., Zacharova, Marija K., Florence, Gordon J., Smith, Terry K.

المساهمون: The Leverhulme Trust, University of St Andrews. School of Chemistry, University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex, University of St Andrews. EaSTCHEM

مصطلحات موضوعية: QH301 Biology, RM Therapeutics. Pharmacology, NDAS, BDC, R2C, SDG 3 - Good Health and Well-being, QH301, RM

وصف الملف: application/pdf

Relation: PLoS Neglected Tropical Diseases; Tulloch , L B , Menzies , S K , Fraser , A L , Gould , E R , King , E F , Zacharova , M K , Florence , G J & Smith , T K 2017 , ' Photo-affinity labelling and biochemical analyses identify the target of trypanocidal simplified natural product analogues ' , PLoS Neglected Tropical Diseases , vol. 11 , no. 9 , e0005886 . https://doi.org/10.1371/journal.pntd.0005886; PURE: 251026018; PURE UUID: 7f83709f-44a1-4e30-8d20-71102ce87b31; RIS: urn:C41BC9504052E3B3093055AFE6BBAFDD; Scopus: 85030718818; ORCID: /0000-0002-8987-5561/work/36874690; ORCID: /0000-0001-7223-5106/work/42522361; ORCID: /0000-0001-9921-4399/work/56638893; WOS: 000412142800033; http://hdl.handle.net/10023/11717; https://doi.org/10.1371/journal.pntd.0005886; http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005886#sec034; RL-2012-025

الاتاحة: http://hdl.handle.net/10023/11717
https://doi.org/10.1371/journal.pntd.0005886
http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005886#sec034

المؤلفون: Gould, Eoin R., King, Elizabeth F. B., Menzies, Stefanie K., Fraser, Andrew L., Tulloch, Lindsay B., Zacharova, Marija K., Smith, Terry K., Florence, Gordon J.

المصدر: Gould , E R , King , E F B , Menzies , S K , Fraser , A L , Tulloch , L B , Zacharova , M K , Smith , T K & Florence , G J 2017 , ' Simplifying nature : towards the design of broad spectrum kinetoplastid inhibitors, inspired by acetogenins ' , Bioorganic & Medicinal Chemistry , vol. 25 , no. 22 , pp. 6126-6136 . https://doi.org/10.1016/j.bmc.2017.01.021

مصطلحات موضوعية: Tetrahydropyran, Neglected tropical diseases, Acetogenins, Natural products

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/simplifying-nature(b05f98d0-3ad9-41f7-b8b8-31c9831397b4).html
https://doi.org/10.1016/j.bmc.2017.01.021
https://research-repository.st-andrews.ac.uk/bitstream/10023/12625/1/EG_GJF_TKS_BMC_2016_256_accepteddraft.pdf